ATE552280T1 - Linsen und materialien mit hohem ionen- und metabolitfluss - Google Patents

Linsen und materialien mit hohem ionen- und metabolitfluss

Info

Publication number
ATE552280T1
ATE552280T1 AT08826490T AT08826490T ATE552280T1 AT E552280 T1 ATE552280 T1 AT E552280T1 AT 08826490 T AT08826490 T AT 08826490T AT 08826490 T AT08826490 T AT 08826490T AT E552280 T1 ATE552280 T1 AT E552280T1
Authority
AT
Austria
Prior art keywords
lenses
materials
high ion
hydrogel
metabolite flow
Prior art date
Application number
AT08826490T
Other languages
English (en)
Inventor
Charles Freeman
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE552280T1 publication Critical patent/ATE552280T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
    • C08F226/10—N-Vinyl-pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
    • C08F220/36—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate containing oxygen in addition to the carboxy oxygen, e.g. 2-N-morpholinoethyl (meth)acrylate or 2-isocyanatoethyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/40—Esters of unsaturated alcohols, e.g. allyl (meth)acrylate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AT08826490T 2007-07-19 2008-07-16 Linsen und materialien mit hohem ionen- und metabolitfluss ATE552280T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95078207P 2007-07-19 2007-07-19
PCT/US2008/070176 WO2009012308A1 (en) 2007-07-19 2008-07-16 High ion and metabolite flux lenses and materials

Publications (1)

Publication Number Publication Date
ATE552280T1 true ATE552280T1 (de) 2012-04-15

Family

ID=39731768

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08826490T ATE552280T1 (de) 2007-07-19 2008-07-16 Linsen und materialien mit hohem ionen- und metabolitfluss

Country Status (14)

Country Link
US (1) US7988729B2 (de)
EP (1) EP2178931B1 (de)
JP (1) JP5415417B2 (de)
AT (1) ATE552280T1 (de)
AU (1) AU2008276088B2 (de)
CA (1) CA2693808C (de)
CY (1) CY1113358T1 (de)
DK (1) DK2178931T3 (de)
ES (1) ES2383110T3 (de)
HR (1) HRP20120332T1 (de)
PL (1) PL2178931T3 (de)
PT (1) PT2178931E (de)
SI (1) SI2178931T1 (de)
WO (1) WO2009012308A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8293858B1 (en) 2009-01-14 2012-10-23 Novartis Ag Ophthalmic and otorhinolaryngological device materials containing a reactive NVP macromer
US8148445B1 (en) 2009-01-14 2012-04-03 Novartis Ag Ophthalmic and otorhinolaryngological device materials containing a multi-arm PEG macromer
WO2014111769A1 (en) 2013-01-15 2014-07-24 Medicem Ophthalmic (Cy) Limited Bioanalogic intraocular lens
WO2017221068A1 (en) 2016-06-23 2017-12-28 Medicem Ophthalmic (Cy) Limited Light-adjustable hydrogel and bioanalogic intraocular lens

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3220960A (en) * 1960-12-21 1965-11-30 Wichterle Otto Cross-linked hydrophilic polymers and articles made therefrom
US3532679A (en) * 1969-04-07 1970-10-06 Robert Steckler Hydrogels from cross-linked polymers of n-vinyl lactams and alkyl acrylates
US3639524A (en) * 1969-07-28 1972-02-01 Maurice Seiderman Hydrophilic gel polymer insoluble in water from polyvinylpyrrolidone with n-vinyl-2-pyrrolidone and methacrylic modifier
US3937680A (en) * 1973-05-29 1976-02-10 Global Vision, Inc. Hydrophilic gel terpolymers from hydrophilic n-vinyl monomers, hydroxyalkyl acrylates or methacrylates and polymerizable unsaturated carboxylic acids
GB1463301A (en) * 1973-07-18 1977-02-02 Highgate D J Polymer properties
US4036788A (en) * 1975-02-11 1977-07-19 Plastomedical Sciences, Inc. Anionic hydrogels based on heterocyclic N-vinyl monomers
US4123407A (en) * 1976-11-26 1978-10-31 American Optical Corporation Hydrophilic contact lens
US4123408A (en) * 1976-11-26 1978-10-31 American Optical Corporation Hydrogel contact lens
US4158089A (en) * 1977-12-27 1979-06-12 Wesley-Jessen Inc. Contact lenses of high water content
US4402887A (en) * 1978-03-14 1983-09-06 Dainippon Ink And Chemicals Inc. Sheet-like articles of polyvinyl chloride
SU1243627A3 (ru) * 1979-12-05 1986-07-07 Дзе Кендалл Компани (Фирма) Гелеобразующа композици
DE3002664C2 (de) * 1980-01-25 1989-05-18 Titmus Eurocon Kontaktlinsen Gmbh & Co Kg, 8750 Aschaffenburg Weiche Kontaktlinse
US4423099A (en) * 1980-07-28 1983-12-27 Ciba-Geigy Corporation Membrane modified hydrogels
US4430458A (en) * 1981-10-08 1984-02-07 Kelvin Lenses Limited Hydrogel-forming polymeric materials
US4440919A (en) * 1981-11-12 1984-04-03 Bausch & Lomb Incorporated Low N-vinyl lactam content based biomedical devices
US4436887A (en) * 1981-11-12 1984-03-13 Bausch & Lomb Incorporated N-Vinyl lactam based biomedical devices
JPS59195621A (ja) 1983-04-22 1984-11-06 Toyo Contact Lens Co Ltd 軟質コンタクトレンズ
US4680336A (en) * 1984-11-21 1987-07-14 Vistakon, Inc. Method of forming shaped hydrogel articles
DE3445093A1 (de) * 1984-12-11 1986-06-19 Bayer Ag, 5090 Leverkusen Hydrophile copolymere, deren verwendung als biomedizinische materialien und hieraus hergestellte kontaktoptische gegenstaende
GB8529006D0 (en) * 1985-11-25 1986-01-02 Highgate D J Hydrophilic materials
GB8601949D0 (en) * 1986-01-28 1986-03-05 Smith & Nephew Ass Hydrogel polymers
US5147394A (en) * 1987-10-09 1992-09-15 Siepser Steven B High refractive index polymeric compositions suitable for use as expansile hydrogel intraocular lenses
US5039459A (en) * 1988-11-25 1991-08-13 Johnson & Johnson Vision Products, Inc. Method of forming shaped hydrogel articles including contact lenses
GB9023498D0 (en) * 1990-10-29 1990-12-12 Biocompatibles Ltd Soft contact lens material
DK0774983T3 (da) * 1995-06-07 2003-03-03 Alcon Lab Inc Forbedrede materialer til oftalmiske linser med højt brydningsindeks
NZ331734A (en) * 1996-03-27 2000-01-28 Novartis Ag Process for manufacture of a porous polymer comprising dispersing a porogen in a monomer phase where the monomer has at least one perfluoropolyether unit and the porogen is a substituted polyalkleneglycol
NZ332034A (en) * 1996-03-27 2000-02-28 Commw Scient Ind Res Org Process for manufacture of a porous polymer and its use as an ophthalmic device or lens
CA2248045C (en) * 1996-04-04 2006-11-07 Novartis Ag High water content porous polymer
US20010018612A1 (en) 1997-08-07 2001-08-30 Carson Daniel R. Intracorneal lens
BR9811081A (pt) * 1997-08-07 2000-08-15 Alcon Lab Inc Lente de difração intracorneal
WO1999011692A1 (en) * 1997-09-03 1999-03-11 The Regents Of The University Of California Novel biomimetic hydrogel materials
TWI230712B (en) * 1998-09-15 2005-04-11 Novartis Ag Polymers
US6281319B1 (en) * 1999-04-12 2001-08-28 Surgidev Corporation Water plasticized high refractive index polymer for ophthalmic applications
SE0303365D0 (sv) * 2003-12-15 2003-12-15 Pharmacia Groningen Bv A phakic intraocular lens with improved fluid circulation properties

Also Published As

Publication number Publication date
CA2693808C (en) 2015-10-20
PT2178931E (pt) 2012-05-28
HRP20120332T1 (hr) 2012-05-31
PL2178931T3 (pl) 2012-08-31
ES2383110T3 (es) 2012-06-18
WO2009012308A1 (en) 2009-01-22
CA2693808A1 (en) 2009-01-22
US20090023835A1 (en) 2009-01-22
EP2178931B1 (de) 2012-04-04
US7988729B2 (en) 2011-08-02
JP5415417B2 (ja) 2014-02-12
SI2178931T1 (sl) 2012-06-29
AU2008276088A1 (en) 2009-01-22
DK2178931T3 (da) 2012-05-07
EP2178931A1 (de) 2010-04-28
AU2008276088B2 (en) 2014-04-03
JP2010533561A (ja) 2010-10-28
CY1113358T1 (el) 2016-06-22

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