ATE551992T1 - Bioresorbierbare polymermatrizes und verfahren zu ihrer herstellung und verwendung - Google Patents

Bioresorbierbare polymermatrizes und verfahren zu ihrer herstellung und verwendung

Info

Publication number: ATE551992T1
Authority: AT; Austria
Prior art keywords: reaction mixture; production; hydrazide; reaction; polymer matrices
Prior art date: 2005-05-27

Application number

AT06771261T

Other languages

English (en)

Inventor

Garfield Royer

Original Assignee

Royer Biomedical Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-05-27

Filing date

2006-05-26

Publication date

2012-04-15

2006-05-26 Application filed by Royer Biomedical Inc filed Critical Royer Biomedical Inc

2012-04-15 Application granted granted Critical

2012-04-15 Publication of ATE551992T1 publication Critical patent/ATE551992T1/de

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/08—Solutions
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- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/34—Macromolecular materials
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
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- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
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- A—HUMAN NECESSITIES
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/426—Immunomodulating agents, i.e. cytokines, interleukins, interferons
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/438—Antigens
- A—HUMAN NECESSITIES
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
- A—HUMAN NECESSITIES
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/64—Animal cells

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Dermatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Transplantation (AREA)
Oral & Maxillofacial Surgery (AREA)
Biomedical Technology (AREA)
Dispersion Chemistry (AREA)
Physical Education & Sports Medicine (AREA)
Immunology (AREA)
Inorganic Chemistry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Neurosurgery (AREA)
Molecular Biology (AREA)
Rheumatology (AREA)
Tropical Medicine & Parasitology (AREA)
Anesthesiology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Materials For Medical Uses (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

AT06771261T 2005-05-27 2006-05-26 Bioresorbierbare polymermatrizes und verfahren zu ihrer herstellung und verwendung ATE551992T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US68497405P	2005-05-27	2005-05-27
PCT/US2006/020380 WO2006130455A2 (en)	2005-05-27	2006-05-26	Bioresorbable polymer matrices and methods of making and using the same

Publications (1)

Publication Number	Publication Date
ATE551992T1 true ATE551992T1 (de)	2012-04-15

Family

ID=37482172

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06771261T ATE551992T1 (de)	2005-05-27	2006-05-26	Bioresorbierbare polymermatrizes und verfahren zu ihrer herstellung und verwendung

Country Status (13)

Country	Link
US (4)	US8039021B2 (de)
EP (1)	EP1898881B1 (de)
JP (2)	JP5319278B2 (de)
KR (2)	KR101536897B1 (de)
CN (1)	CN101247789B (de)
AT (1)	ATE551992T1 (de)
AU (1)	AU2006252730B2 (de)
BR (1)	BRPI0610469A2 (de)
CA (1)	CA2608432C (de)
ES (1)	ES2387195T3 (de)
MX (1)	MX2007014848A (de)
PL (1)	PL1898881T3 (de)
WO (1)	WO2006130455A2 (de)

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DE102006016598A1 (de) *	2006-04-06	2007-11-15	Heraeus Kulzer Gmbh	Beschichtete Vaskulärimplantate
PT104879B (pt) *	2009-12-10	2012-10-17	Univ Do Minho	Hidrogel de dextrino para aplicações biomédicas
US8197849B2 (en)	2010-02-12	2012-06-12	National Health Research Institutes	Cross-linked oxidated hyaluronic acid for use as a vitreous substitute
US20130245549A1 (en) *	2011-09-14	2013-09-19	Royer Biomedical, Inc.	Bioresorable drug delivery matrices based on cross-linked polysaccharides, dosage forms designed for delayed/controlled release
PL221351B1 (pl) *	2012-03-14	2016-03-31	Politechnika Warszawska	Sposób otrzymywania nanocząstek polisacharydowych
US20130303983A1 (en) *	2012-05-09	2013-11-14	Cook Medical Technologies Llc	Coated medical devices including a water-insoluble therapeutic agent
GB2503949A (en) *	2012-07-14	2014-01-15	Nobel Biocare Services Ag	An agent for promoting osseointegration of implants
CN106748951B (zh)	2012-07-19	2020-07-24	开曼化学股份有限公司	作为在治疗ep4介导的疾病和病状中使用的ep4受体选择性激动剂的二氟内酰胺化合物
GB2504679A (en)	2012-08-03	2014-02-12	Nobel Biocare Services Ag	Bone substitute structure and material
ITVI20130019A1 (it) *	2013-01-29	2014-07-30	Univ Padova	Biomateriale per dispositivi medici, in particolare protesi
CN105051186B (zh)	2013-02-12	2018-11-02	复制细胞生命科学公司	治疗和修复肌腱的组合物和方法
JP2015000208A (ja) *	2013-06-17	2015-01-05	株式会社ジーシー	骨折部治療用部材
KR20160048054A (ko)	2013-07-19	2016-05-03	카이맨 케미칼 컴파니 인코포레이티드	골 성장의 촉진을 위한 방법, 시스템 및 조성물
US20150133561A1 (en)	2013-11-12	2015-05-14	Vizuri Health Sciences Llc	Aqueous based capsaicinoid formulations and methods of manufacture and use
TW201538730A (zh)	2014-02-12	2015-10-16	Replicel Life Sciences Inc	用於治療骨骼、關節及軟骨之組合物及方法
US9956190B2 (en)	2014-04-15	2018-05-01	Vizuri Health Sciences Llc	Topical compositions for pain relief, manufacture and use
DK3242869T3 (da) *	2015-01-06	2022-01-31	Cellix Bio Private Ltd	Sammensætninger og fremgangsmåder til behanding af inflammation og smerte
JP6853785B2 (ja) *	2015-11-12	2021-03-31	テルモ株式会社	徐放性局所投与剤
US11752099B2 (en)	2017-03-27	2023-09-12	W. L. Gore & Associates, Inc.	Injectable and biodegradable polymer formulations for controlled release of bioactive agents
PL424773A1 (pl) *	2018-03-06	2019-09-09	Nanovelos Spółka Akcyjna	Enkapsulowana polisacharydem antracyklina do zastosowania w leczeniu nowotworów
WO2022072930A1 (en) *	2020-10-02	2022-04-07	Petrychenko Dmitri	Extended release devices and therapeutics for long term treatment of urinary tract infection in-vivo

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WO1990003401A1 (en) *	1988-09-30	1990-04-05	Neorx Corporation	Targeting substance-diagnostic/therapeutic agent conjugates having schiff base linkages
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JP2000511512A (ja) *	1996-05-03	2000-09-05	イノジェネティックス・ナムローゼ・フェンノートシャップ	酸化ポリサッカライドで架橋したゼラチンを含有する新規医薬
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WO2003101425A2 (en) *	2002-06-03	2003-12-11	Alnis Biosciences, Inc.	Therapeutic agent-containing polymeric nanoarticles
DE10262176B4 (de) *	2002-06-21	2007-10-04	Heraeus Kulzer Gmbh	Verfahren zur Herstellung von antibiotisch beschichteten porösen Körpern sowie Verwendung
DE10228103A1 (de)	2002-06-24	2004-01-15	Bayer Cropscience Ag	Fungizide Wirkstoffkombinationen
EP1638530A2 (de) *	2003-06-20	2006-03-29	Royer Biomedical, INC.	Arzneimittel-polymer-komplexe
EP2514445B1 (de) *	2003-10-22	2018-07-18	Encelle, Inc.	Bioaktive Hydrogel-Zusammensetzungen zur Regeneration von Bindegewebe

2006
- 2006-05-26 AU AU2006252730A patent/AU2006252730B2/en not_active Ceased
- 2006-05-26 ES ES06771261T patent/ES2387195T3/es active Active
- 2006-05-26 KR KR1020147008571A patent/KR101536897B1/ko not_active IP Right Cessation
- 2006-05-26 EP EP06771261A patent/EP1898881B1/de not_active Not-in-force
- 2006-05-26 PL PL06771261T patent/PL1898881T3/pl unknown
- 2006-05-26 MX MX2007014848A patent/MX2007014848A/es active IP Right Grant
- 2006-05-26 JP JP2008513748A patent/JP5319278B2/ja not_active Expired - Fee Related
- 2006-05-26 WO PCT/US2006/020380 patent/WO2006130455A2/en active Application Filing
- 2006-05-26 BR BRPI0610469-0A patent/BRPI0610469A2/pt not_active IP Right Cessation
- 2006-05-26 CA CA2608432A patent/CA2608432C/en not_active Expired - Fee Related
- 2006-05-26 CN CN2006800271967A patent/CN101247789B/zh not_active Expired - Fee Related
- 2006-05-26 KR KR1020077027633A patent/KR101465994B1/ko not_active IP Right Cessation
- 2006-05-26 AT AT06771261T patent/ATE551992T1/de active
2007
- 2007-11-09 US US11/983,454 patent/US8039021B2/en not_active Expired - Fee Related
2011
- 2011-09-08 US US13/228,267 patent/US8435565B2/en not_active Expired - Fee Related
2013
- 2013-04-22 US US13/867,929 patent/US8664280B2/en not_active Expired - Fee Related
- 2013-05-20 JP JP2013106109A patent/JP5744104B2/ja not_active Expired - Fee Related
2014
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Also Published As

Publication number	Publication date
JP2013155204A (ja)	2013-08-15
AU2006252730B2 (en)	2012-01-19
US20110318416A1 (en)	2011-12-29
AU2006252730A1 (en)	2006-12-07
WO2006130455A3 (en)	2007-04-05
KR20140044950A (ko)	2014-04-15
CA2608432A1 (en)	2006-12-07
CN101247789B (zh)	2012-06-27
KR101536897B1 (ko)	2015-07-15
CN101247789A (zh)	2008-08-20
US8664280B2 (en)	2014-03-04
KR101465994B1 (ko)	2014-11-27
JP5744104B2 (ja)	2015-07-01
US9089609B2 (en)	2015-07-28
JP2008542295A (ja)	2008-11-27
KR20080016578A (ko)	2008-02-21
US20140248298A1 (en)	2014-09-04
MX2007014848A (es)	2009-02-20
WO2006130455A2 (en)	2006-12-07
ES2387195T3 (es)	2012-09-17
PL1898881T3 (pl)	2012-10-31
US20080069894A1 (en)	2008-03-20
JP5319278B2 (ja)	2013-10-16
CA2608432C (en)	2013-08-06
US8435565B2 (en)	2013-05-07
EP1898881A4 (de)	2010-12-22
US8039021B2 (en)	2011-10-18
EP1898881B1 (de)	2012-04-04
BRPI0610469A2 (pt)	2012-10-23
EP1898881A2 (de)	2008-03-19
US20130237614A1 (en)	2013-09-12

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