ATE54920T1 - 2,3-diamino-2,3-didesoxyhexose-derivate, verfahren zu ihrer herstellung und ihre verwendung. - Google Patents

2,3-diamino-2,3-didesoxyhexose-derivate, verfahren zu ihrer herstellung und ihre verwendung.

Info

Publication number
ATE54920T1
ATE54920T1 AT85902023T AT85902023T ATE54920T1 AT E54920 T1 ATE54920 T1 AT E54920T1 AT 85902023 T AT85902023 T AT 85902023T AT 85902023 T AT85902023 T AT 85902023T AT E54920 T1 ATE54920 T1 AT E54920T1
Authority
AT
Austria
Prior art keywords
pct
didesoxyhexose
diamino
derivatives
preparation
Prior art date
Application number
AT85902023T
Other languages
English (en)
Inventor
Ingolf Macher
Frank Michael Unger
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19843415100 external-priority patent/DE3415100A1/de
Priority claimed from DE19843415102 external-priority patent/DE3415102A1/de
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of ATE54920T1 publication Critical patent/ATE54920T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06Aminosugars
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4162,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04Phosphates; Phosphites; Polyphosphates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06Fatty acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18Acyclic radicals, substituted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT85902023T 1984-04-21 1985-04-17 2,3-diamino-2,3-didesoxyhexose-derivate, verfahren zu ihrer herstellung und ihre verwendung. ATE54920T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19843415100 DE3415100A1 (de) 1984-04-21 1984-04-21 Neue 2,3-diamino-2,3-didesoxyhexosederivate, verfahren zu ihrer herstellung und ihre verwendung
DE19843415102 DE3415102A1 (de) 1984-04-21 1984-04-21 Neue 2,3-diamino-2,3-didesoxyhexosederivate, verfahren zu ihrer herstellung und ihre verwendung
PCT/EP1985/000171 WO1985004881A1 (en) 1984-04-21 1985-04-17 2,3-dinamo-2,3-didesoxyhexose derivatives, processes for their preparation and their use
EP85902023A EP0180608B1 (de) 1984-04-21 1985-04-17 2,3-diamino-2,3-didesoxyhexose-derivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
ATE54920T1 true ATE54920T1 (de) 1990-08-15

Family

ID=25820628

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85902023T ATE54920T1 (de) 1984-04-21 1985-04-17 2,3-diamino-2,3-didesoxyhexose-derivate, verfahren zu ihrer herstellung und ihre verwendung.

Country Status (16)

Country Link
US (1) US4698331A (de)
EP (1) EP0180608B1 (de)
AT (1) ATE54920T1 (de)
AU (1) AU580061B2 (de)
CA (1) CA1264739A (de)
DE (1) DE3578866D1 (de)
DK (1) DK600585A (de)
ES (1) ES8605531A1 (de)
FI (1) FI81807C (de)
GR (1) GR850955B (de)
HU (1) HU197584B (de)
IL (1) IL75042A (de)
NZ (1) NZ211846A (de)
PH (1) PH23127A (de)
PT (1) PT80320B (de)
WO (1) WO1985004881A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8601551A (nl) * 1985-06-28 1987-01-16 Sandoz Ag Nieuwe saccharides, hun bereiding en farmaceutische samenstellingen, die hen bevatten.
DE3731953A1 (de) 1987-09-23 1989-04-06 Sandoz Ag Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung
US5219843A (en) * 1987-09-23 1993-06-15 Sandoz Ltd. Saccharide derivatives
CN1372564A (zh) * 2000-02-10 2002-10-02 三井化学株式会社 选择性制备1-磷酸化糖衍生物端基异构体的方法和制备核苷的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR78246B (de) * 1981-01-23 1984-09-26 Ciba Geigy Ag
US4384998A (en) * 1981-03-30 1983-05-24 Merck & Co., Inc. Synthesis of thienamycin from D-glucose
DE3220426A1 (de) * 1982-05-29 1983-12-01 Behringwerke Ag, 3550 Marburg Chemische verbindung, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung der malaria
EP0143840B1 (de) * 1983-05-06 1990-08-29 Wisconsin Alumni Research Foundation Monosaccharide verbindungen mit immunostimulierender wirkung
US4481196A (en) * 1983-08-31 1984-11-06 Fujisawa Pharmaceutical Co., Ltd. Glycoside phosphate derivatives, pharmaceutical composition of the same and method of use
DE3347163A1 (de) * 1983-12-27 1985-07-04 Behringwerke Ag, 3550 Marburg Verwendung von oligosacchariden zur chemotherapie oder chemoprophylaxe der malaria
US4481198A (en) * 1984-02-13 1984-11-06 Wisconsin Alumni Research Foundation Vitamin D metabolism inhibitor

Also Published As

Publication number Publication date
AU580061B2 (en) 1988-12-22
GR850955B (de) 1985-11-25
FI855132A0 (fi) 1985-12-20
WO1985004881A1 (en) 1985-11-07
EP0180608B1 (de) 1990-07-25
HU197584B (en) 1989-04-28
CA1264739A (en) 1990-01-23
PH23127A (en) 1989-05-05
HUT42099A (en) 1987-06-29
IL75042A (en) 1989-05-15
AU4238085A (en) 1985-11-15
ES8605531A1 (es) 1986-03-16
NZ211846A (en) 1989-07-27
DE3578866D1 (de) 1990-08-30
FI81807C (fi) 1990-12-10
FI81807B (fi) 1990-08-31
ES542416A0 (es) 1986-03-16
PT80320A (en) 1985-05-01
US4698331A (en) 1987-10-06
IL75042A0 (en) 1985-08-30
EP0180608A1 (de) 1986-05-14
DK600585D0 (da) 1985-12-20
DK600585A (da) 1985-12-20
FI855132A (fi) 1985-12-20
PT80320B (en) 1987-02-16

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