ATE540996T1 - Polymerbasierter serumalbumin-ersatzstoff - Google Patents
Polymerbasierter serumalbumin-ersatzstoffInfo
- Publication number
- ATE540996T1 ATE540996T1 AT06752773T AT06752773T ATE540996T1 AT E540996 T1 ATE540996 T1 AT E540996T1 AT 06752773 T AT06752773 T AT 06752773T AT 06752773 T AT06752773 T AT 06752773T AT E540996 T1 ATE540996 T1 AT E540996T1
- Authority
- AT
- Austria
- Prior art keywords
- substitute
- polymer based
- serum albumine
- based serum
- molecular weight
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title abstract 3
- 210000002966 serum Anatomy 0.000 title 1
- 229920000223 polyglycerol Polymers 0.000 abstract 2
- 239000004721 Polyphenylene oxide Substances 0.000 abstract 1
- 102000007562 Serum Albumin Human genes 0.000 abstract 1
- 108010071390 Serum Albumin Proteins 0.000 abstract 1
- 229920006158 high molecular weight polymer Polymers 0.000 abstract 1
- 229920000570 polyether Polymers 0.000 abstract 1
- 229920005862 polyol Polymers 0.000 abstract 1
- 150000003077 polyols Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
- C09K23/42—Ethers, e.g. polyglycol ethers of alcohols or phenols
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G2650/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterized by the type of post-polymerisation functionalisation
- C08G2650/04—End-capping
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
- C08G2650/30—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type branched
- C08G2650/32—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type branched dendritic or similar
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
- C08G2650/38—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type containing oxygen in addition to the ether group
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Materials Engineering (AREA)
- Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Polyethers (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68733605P | 2005-06-06 | 2005-06-06 | |
PCT/CA2006/000936 WO2006130978A1 (en) | 2005-06-06 | 2006-06-06 | Polymer-based serum albumin substitute |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE540996T1 true ATE540996T1 (de) | 2012-01-15 |
Family
ID=37498077
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06752773T ATE540996T1 (de) | 2005-06-06 | 2006-06-06 | Polymerbasierter serumalbumin-ersatzstoff |
Country Status (5)
Country | Link |
---|---|
US (2) | US9346029B2 (de) |
EP (1) | EP1891143B1 (de) |
AT (1) | ATE540996T1 (de) |
CA (1) | CA2653541C (de) |
WO (1) | WO2006130978A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2653541C (en) | 2005-06-06 | 2014-12-23 | The University Of British Columbia | Polymer-based serum albumin substitute |
CN101883810A (zh) * | 2007-09-11 | 2010-11-10 | 巴斯夫欧洲公司 | 聚甘油抗微生物剂和组合物 |
CA2742345A1 (en) * | 2007-11-02 | 2009-05-07 | The University Of British Columbia | Hyperbranched polyglycerol for improving heart function |
US8220643B2 (en) * | 2008-06-06 | 2012-07-17 | Fresenius Medical Care Holdings, Inc. | Urea sorbent |
CN101724147B (zh) * | 2009-12-03 | 2011-09-28 | 苏州大学 | 一种超支化聚苯醚及其制备方法 |
AU2015221541B2 (en) * | 2010-03-01 | 2017-03-09 | Centre For Drug Research And Development | Derivatized hyperbranched polyglycerols |
CA2791416C (en) | 2010-03-01 | 2018-05-15 | The University Of British Columbia | Derivatized hyperbranched polyglycerols |
PE20150288A1 (es) * | 2012-04-24 | 2015-02-22 | Univ British Columbia | Dialisato a base de polimero |
US20160295856A1 (en) | 2013-11-21 | 2016-10-13 | University Of British Columbia | Polymer based transplant preservation solution |
CN105622922B (zh) * | 2016-04-06 | 2018-04-20 | 苏州博纳化学科技有限公司 | 一种亲水性双羟基化合物的制备方法 |
WO2019087084A1 (en) | 2017-11-02 | 2019-05-09 | Eman Biodiscoveries Sd. Bhd. | Extract of orthosiphon stamineus, formulations, and uses thereof |
US20180251574A1 (en) * | 2018-05-02 | 2018-09-06 | Arc Medical Devices Inc. | Fucan-dendrimer based compounds and complexes |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2601675B1 (fr) | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
US5112876A (en) | 1988-10-28 | 1992-05-12 | Takeda Chemical Industries, Ltd. | Polyether polyol and rigid polyurethane foam |
US5407528A (en) | 1992-07-28 | 1995-04-18 | The Center For Innovative Technology | Oxygen plasma resistant polymeric film and fiber forming macromolecules containing the phosphine oxide moiety |
US5407428A (en) * | 1993-06-04 | 1995-04-18 | Biotime, Inc. | Solutions for use as plasma expanders and substitutes |
US5635571A (en) * | 1995-06-30 | 1997-06-03 | Cornell Research Foundation, Inc. | Polymerizable macromonomers and polymers prepared therefrom |
US5688977A (en) | 1996-02-29 | 1997-11-18 | Napro Biotherapeutics, Inc. | Method for docetaxel synthesis |
WO1998043555A1 (en) | 1997-04-03 | 1998-10-08 | Point Biomedical Corporation | Intravesical drug delivery system |
US20020164374A1 (en) | 1997-10-29 | 2002-11-07 | John Jackson | Polymeric systems for drug delivery and uses thereof |
WO2002085337A1 (en) | 2001-04-20 | 2002-10-31 | The University Of British Columbia | Micellar drug delivery systems for hydrophobic drugs |
US6822068B2 (en) | 1998-12-22 | 2004-11-23 | Bayer Aktiengesellschaft | Method for producing highly-branched glycidol-based polyols |
WO2000077070A2 (en) | 1999-06-09 | 2000-12-21 | Ucb, S.A. | Modified hyperbranched polyester polymers, processes for preparing them and uses of them |
AUPQ259399A0 (en) | 1999-09-01 | 1999-09-23 | Lustre Investments Pte Ltd | Therapeutic agents |
US6949335B2 (en) | 1999-11-30 | 2005-09-27 | 21St Century Medicine, Inc. | Polyglycerol and lactose compositions for the protection of living systems from states of reduced metabolism |
WO2001095351A1 (fr) * | 2000-06-07 | 2001-12-13 | Nisshinbo Industries, Inc. | Composition d'electrolyte pour condensateur electrique double couche, electrolyte polymere solide, composition pour electrode polarisable, electrode polarisable et condensateur electrique double couche |
TWI246524B (en) | 2001-01-19 | 2006-01-01 | Shearwater Corp | Multi-arm block copolymers as drug delivery vehicles |
US7265186B2 (en) | 2001-01-19 | 2007-09-04 | Nektar Therapeutics Al, Corporation | Multi-arm block copolymers as drug delivery vehicles |
DE10121807A1 (de) | 2001-05-04 | 2002-11-07 | Bayer Ag | Verfahren zur Herstellung von Polyetherpolyolen |
US7063860B2 (en) | 2001-08-13 | 2006-06-20 | University Of Pittsburgh | Application of lipid vehicles and use for drug delivery |
ES2283585T3 (es) * | 2001-08-22 | 2007-11-01 | Supramol Parenteral Colloids Gmbh | Amilopectina hiperramificada para su utloizacion en procedimientos para el tratamiento quirurgico o terapeutico de mamiferos o en procedimientos de diagnostico, especialmente para su uso como extensor del volumen de plasma. |
PT1864660E (pt) | 2001-11-01 | 2011-03-31 | Spectrum Pharmaceuticals Inc | Composições médicas para o tratamento intravesical do cancro da bexiga |
DE10203058A1 (de) * | 2002-01-26 | 2003-07-31 | Bayer Ag | Dentritisch modifizierte Polyurethane |
KR100573289B1 (ko) | 2002-07-20 | 2006-04-24 | 대화제약 주식회사 | 방광내 투여를 통한 방광암치료용 파클리탁셀 조성물 및그의 제조 방법 |
DE10237442B4 (de) * | 2002-08-16 | 2004-08-19 | Fresenius Kabi Deutschland Gmbh | Hochverzweigte, niedrig substituierte Stärkeprodukte |
EP1663171B9 (de) | 2003-08-26 | 2009-08-19 | SmithKline Beecham Corporation | heterofunktionelle copolymere von glycerol und polyethylenglykol, ihre konjugate und zusammensetzungen |
LT1675622T (lt) | 2003-09-17 | 2017-09-11 | Nektar Therapeutics | Daugiašakio polimero provaistai |
WO2005079856A1 (en) | 2004-02-23 | 2005-09-01 | The University Of British Columbia | Drug delivery compositions comprising hydrophobic polymers and amphipathic molecules |
US7396861B2 (en) * | 2004-07-15 | 2008-07-08 | Agfa Graphics Nv | Radiation curable compositions |
US7875698B2 (en) * | 2004-07-15 | 2011-01-25 | Agfa Graphics Nv | Polymeric initiators |
CA2653541C (en) | 2005-06-06 | 2014-12-23 | The University Of British Columbia | Polymer-based serum albumin substitute |
JP2010506932A (ja) | 2006-10-20 | 2010-03-04 | シノファーム シンガポール ピーティーイー,リミテッド | 結晶性の無水ドセタキセルの製造方法 |
AU2007325631B9 (en) | 2006-11-30 | 2014-01-30 | Nektar Therapeutics | Method for preparing a polymer conjugate |
WO2008074154A1 (en) | 2006-12-18 | 2008-06-26 | The University Of British Columbia | Polymers comprising zwitterionic endgroups |
KR100878455B1 (ko) | 2007-04-10 | 2009-01-13 | 한미약품 주식회사 | 안정한 무수결정형 도세탁셀 및 이의 제조방법 |
CA2742345A1 (en) | 2007-11-02 | 2009-05-07 | The University Of British Columbia | Hyperbranched polyglycerol for improving heart function |
WO2009123934A2 (en) | 2008-03-29 | 2009-10-08 | Emory University | Branched multifunctional nanoparticle conjugates and their use |
EP2123304A1 (de) | 2008-05-23 | 2009-11-25 | Freie Universität Berlin | Verbindungen geeignet als Nanoträger für aktive Substanzen und ihre Verwendungen |
CA2791416C (en) | 2010-03-01 | 2018-05-15 | The University Of British Columbia | Derivatized hyperbranched polyglycerols |
WO2012031245A1 (en) | 2010-09-03 | 2012-03-08 | North Carolina Central University | Biodegradable liquogel and ph sensitive nanocarriers |
WO2012162789A1 (en) | 2011-06-01 | 2012-12-06 | University Of British Columbia | Polymers for reversing heparin-based anticoagulation |
PE20150288A1 (es) | 2012-04-24 | 2015-02-22 | Univ British Columbia | Dialisato a base de polimero |
-
2006
- 2006-06-06 CA CA2653541A patent/CA2653541C/en not_active Expired - Fee Related
- 2006-06-06 EP EP06752773A patent/EP1891143B1/de not_active Not-in-force
- 2006-06-06 WO PCT/CA2006/000936 patent/WO2006130978A1/en active Application Filing
- 2006-06-06 US US11/916,525 patent/US9346029B2/en active Active
- 2006-06-06 AT AT06752773T patent/ATE540996T1/de active
-
2016
- 2016-04-18 US US15/131,559 patent/US9789056B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2653541A1 (en) | 2006-12-14 |
EP1891143A1 (de) | 2008-02-27 |
US9789056B2 (en) | 2017-10-17 |
EP1891143A4 (de) | 2009-07-15 |
US9346029B2 (en) | 2016-05-24 |
US20170042804A1 (en) | 2017-02-16 |
CA2653541C (en) | 2014-12-23 |
WO2006130978A1 (en) | 2006-12-14 |
EP1891143B1 (de) | 2012-01-11 |
US20080292579A1 (en) | 2008-11-27 |
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