ATE540023T1 - NOVEL 3-AMINOALKYL-1,3-DIHYDRO-2H-INDOL-2-ON DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE - Google Patents

NOVEL 3-AMINOALKYL-1,3-DIHYDRO-2H-INDOL-2-ON DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE

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Publication number
ATE540023T1
ATE540023T1 AT09721627T AT09721627T ATE540023T1 AT E540023 T1 ATE540023 T1 AT E540023T1 AT 09721627 T AT09721627 T AT 09721627T AT 09721627 T AT09721627 T AT 09721627T AT E540023 T1 ATE540023 T1 AT E540023T1
Authority
AT
Austria
Prior art keywords
indol
aminoalkyl
dihydro
derivatives
novel
Prior art date
Application number
AT09721627T
Other languages
German (de)
Inventor
Loic Foulon
Laurent Goullieux
Brigitte Pouzet
Gal Claudine Serradeil-Le
Gerard Valette
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Application granted granted Critical
Publication of ATE540023T1 publication Critical patent/ATE540023T1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
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AT09721627T 2008-02-19 2009-02-18 NOVEL 3-AMINOALKYL-1,3-DIHYDRO-2H-INDOL-2-ON DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE ATE540023T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0800866A FR2927625B1 (en) 2008-02-19 2008-02-19 NOVEL 3-AMINOALKYL-1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
PCT/FR2009/000179 WO2009115685A1 (en) 2008-02-19 2009-02-18 Novel 3-aminoalkyl-1,3-dihydro-2h-indol-2-one derivatives, preparation thereof and therapeutic use thereof.

Publications (1)

Publication Number Publication Date
ATE540023T1 true ATE540023T1 (en) 2012-01-15

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AT09721627T ATE540023T1 (en) 2008-02-19 2009-02-18 NOVEL 3-AMINOALKYL-1,3-DIHYDRO-2H-INDOL-2-ON DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE

Country Status (15)

Country Link
US (1) US8362067B2 (en)
EP (1) EP2265582B1 (en)
JP (1) JP5602639B2 (en)
KR (1) KR20100126401A (en)
CN (1) CN102015642A (en)
AR (1) AR070438A1 (en)
AT (1) ATE540023T1 (en)
AU (1) AU2009227111A1 (en)
BR (1) BRPI0907578A2 (en)
CA (1) CA2716035A1 (en)
FR (1) FR2927625B1 (en)
IL (1) IL207629A0 (en)
MX (1) MX2010009092A (en)
RU (1) RU2010138575A (en)
WO (1) WO2009115685A1 (en)

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FR2927625B1 (en) 2008-02-19 2010-03-12 Sanofi Aventis NOVEL 3-AMINOALKYL-1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
US9376424B2 (en) 2010-07-01 2016-06-28 Azevan Pharmaceuticals, Inc. Methods for treating post traumatic stress disorder
JP7255967B2 (en) * 2014-03-28 2023-04-11 アゼヴァン ファーマスーティカルズ，インコーポレイテッド Compositions and methods for treating neurodegenerative diseases
CN104592088B (en) * 2015-01-05 2019-01-01 内蒙古工业大学 The method that laurel acid catalysis prepares 3- amine alkyl-indol
CN105061290B (en) * 2015-08-28 2017-11-10 福建品派包装有限公司 A kind of synthetic method of indole ketone compound
CN105061291B (en) * 2015-09-08 2017-08-04 江俞 A kind of synthetic method of miscellaneous thick cyclosubstituted indole ketone compound
BR112020005107A2 (en) 2017-09-15 2020-11-03 Azevan Pharmaceuticals, Inc. compositions and methods for the treatment of brain injury
CN108675945B (en) * 2018-06-22 2020-09-22 湖南科技大学 ((2-hydroxybenzyl) amido) phenylurea compound and preparation method and application thereof

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AU550845B2 (en) 1981-03-30 1986-04-10 Sumitomo Chemical Company, Limited Tetrahydrophthalimides and their starting compounds
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BRPI0907578A2 (en) 2019-09-24
JP2011512389A (en) 2011-04-21
US8362067B2 (en) 2013-01-29
AU2009227111A1 (en) 2009-09-24
WO2009115685A1 (en) 2009-09-24
EP2265582B1 (en) 2012-01-04
MX2010009092A (en) 2011-09-21
JP5602639B2 (en) 2014-10-08
FR2927625A1 (en) 2009-08-21
EP2265582A1 (en) 2010-12-29
US20110059955A1 (en) 2011-03-10
CA2716035A1 (en) 2009-09-24
IL207629A0 (en) 2010-12-30
CN102015642A (en) 2011-04-13

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