ATE537183T1 - Hiv-fusionshemmerpeptide mit verbesserten biologischen eigenschaften - Google Patents
Hiv-fusionshemmerpeptide mit verbesserten biologischen eigenschaftenInfo
- Publication number
- ATE537183T1 ATE537183T1 AT07749903T AT07749903T ATE537183T1 AT E537183 T1 ATE537183 T1 AT E537183T1 AT 07749903 T AT07749903 T AT 07749903T AT 07749903 T AT07749903 T AT 07749903T AT E537183 T1 ATE537183 T1 AT E537183T1
- Authority
- AT
- Austria
- Prior art keywords
- biological properties
- fusion inhibitor
- improved biological
- hiv fusion
- inhibitor peptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
- G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- G01N2333/16—HIV-1, HIV-2
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76467406P | 2006-02-02 | 2006-02-02 | |
PCT/US2007/002990 WO2007097903A2 (en) | 2006-02-02 | 2007-02-02 | Hiv fusion inhibitor peptides with improved biological properties |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE537183T1 true ATE537183T1 (de) | 2011-12-15 |
Family
ID=38437849
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07749903T ATE537183T1 (de) | 2006-02-02 | 2007-02-02 | Hiv-fusionshemmerpeptide mit verbesserten biologischen eigenschaften |
Country Status (15)
Country | Link |
---|---|
US (3) | US7456251B2 (de) |
EP (1) | EP1989220B1 (de) |
JP (1) | JP4682251B2 (de) |
CN (1) | CN101415723B (de) |
AR (2) | AR059300A1 (de) |
AT (1) | ATE537183T1 (de) |
AU (1) | AU2007218025A1 (de) |
CA (1) | CA2651793C (de) |
CY (1) | CY1113115T1 (de) |
DK (1) | DK1989220T3 (de) |
ES (1) | ES2381631T3 (de) |
NZ (1) | NZ570300A (de) |
PT (1) | PT1989220E (de) |
TW (1) | TWI341844B (de) |
WO (1) | WO2007097903A2 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI341844B (en) | 2006-02-02 | 2011-05-11 | Trimeris Inc | Hiv fusion inhibitor peptides with improved biological properties |
EP2201028A2 (de) * | 2007-09-25 | 2010-06-30 | Trimeris, Inc. | Neues verfahren zur synthese therapeutischer antiviraler peptide |
US8828931B2 (en) * | 2008-05-28 | 2014-09-09 | New York Blood Center, Inc. | Bifunctional molecules for inhibiting HIV entry |
AU2009281992A1 (en) * | 2008-08-13 | 2010-02-18 | New York Blood Center | Combination therapy of HIV fusion/entry inhibitors targeting gp41 |
CA2739288A1 (en) * | 2008-10-16 | 2010-04-22 | Shibo Jiang | Immunoenhancer-linked oligomeric hiv vaccines |
WO2010047826A2 (en) * | 2008-10-24 | 2010-04-29 | Trimeris, Inc. | Dosing regimens and dosage formulations of an antiviral peptide therapeutic |
CA2751865A1 (en) * | 2009-02-09 | 2010-08-12 | New York Blood Center, Inc. | Trimeric hiv fusion inhibitors for treating or preventing hiv infection |
CN102883740B (zh) | 2010-05-03 | 2015-10-14 | 纽约血库公司 | 用于使hiv失活并阻断hiv的双功能分子 |
CN104159914A (zh) * | 2011-12-19 | 2014-11-19 | 爱尔兰詹森研发公司 | Hiv膜融合抑制剂 |
WO2013150532A1 (en) | 2012-04-04 | 2013-10-10 | Yeda Research And Development Co. Ltd. | Lipopeptide conjugates comprising sphingolipid and hiv gp41 derived peptides |
CN103724404B (zh) * | 2013-12-08 | 2016-11-02 | 北京工业大学 | 抑制hiv病毒与宿主细胞融合的非对映体多肽及其用途 |
GB201509782D0 (en) * | 2015-06-05 | 2015-07-22 | Isis Innovation | Methods and products for fusion protein synthesis |
CN109320593A (zh) * | 2018-11-05 | 2019-02-12 | 中国人民解放军军事科学院军事医学研究院 | 抑制hiv感染的螺旋多肽及其用途 |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
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US4016273A (en) | 1975-07-16 | 1977-04-05 | American Cyanamid Company | Sustained release forms of certain oxazepines for parenteral administration |
JPS55154991A (en) | 1979-05-23 | 1980-12-02 | Hisamitsu Pharmaceut Co Inc | Beta-d-fructopyranoside derivative |
IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
US4530840A (en) | 1982-07-29 | 1985-07-23 | The Stolle Research And Development Corporation | Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents |
US5411951A (en) | 1984-10-04 | 1995-05-02 | Monsanto Company | Prolonged release of biologically active somatotropin |
US4629783A (en) | 1985-04-29 | 1986-12-16 | Genetic Systems Corporation | Synthetic antigen for the detection of AIDS-related disease |
US5234520A (en) | 1987-03-20 | 1993-08-10 | Morgan Adhesives Co. | Method of making an adhesive construction |
CN1030256A (zh) * | 1987-06-29 | 1989-01-11 | 日清食品株式会社 | 检测和治疗人类免疫缺陷病毒的方法和物质 |
US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
US5462863A (en) | 1989-02-09 | 1995-10-31 | Development Center For Biotechnology | Isolation of Hepatitis B surface antigen from transformed yeast cells |
US5776963A (en) | 1989-05-19 | 1998-07-07 | Hoechst Marion Roussel, Inc. | 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility |
AU2791792A (en) | 1991-10-04 | 1993-05-03 | Robert H. Cornett | Approaching emergency vehicle warning system |
NZ254640A (en) | 1992-07-20 | 1997-04-24 | Univ Duke | Hiv protein fragments of transmembrane glycoprotein gp41 (dp-107) with antiviral activity and their use |
US5728553A (en) | 1992-09-23 | 1998-03-17 | Delta Biotechnology Limited | High purity albumin and method of producing |
CN1108823C (zh) | 1993-02-23 | 2003-05-21 | 基因技术股份有限公司 | 运用赋形剂对有机溶剂处理的多肽的稳定化方法 |
US6479055B1 (en) | 1993-06-07 | 2002-11-12 | Trimeris, Inc. | Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission |
US5464933A (en) | 1993-06-07 | 1995-11-07 | Duke University | Synthetic peptide inhibitors of HIV transmission |
GB9404270D0 (en) | 1994-03-05 | 1994-04-20 | Delta Biotechnology Ltd | Yeast strains and modified albumins |
US6004549A (en) | 1994-12-14 | 1999-12-21 | Schering Corporation | Crystalline protein controlled release compositions |
WO1996040191A1 (en) | 1995-06-07 | 1996-12-19 | Trimeris, Inc. | The treatment of hiv and other viral infections using combinatory therapy |
US6413536B1 (en) | 1995-06-07 | 2002-07-02 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system and medical or surgical device |
US5747058A (en) | 1995-06-07 | 1998-05-05 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system |
ZA965368B (en) | 1995-07-14 | 1997-01-14 | Novo Nordisk As | A pharmaceutical formulation |
US20020064546A1 (en) | 1996-09-13 | 2002-05-30 | J. Milton Harris | Degradable poly(ethylene glycol) hydrogels with controlled half-life and precursors therefor |
US6191107B1 (en) | 1997-09-26 | 2001-02-20 | Takeda Chemical Industries, Ltd. | Complex of human growth hormone and zinc |
WO1999033489A1 (fr) | 1997-12-26 | 1999-07-08 | Yamanouchi Pharmaceutical Co., Ltd. | Compositions medicinales a liberation prolongee |
JPH11209456A (ja) * | 1998-01-29 | 1999-08-03 | Hitachi Chem Co Ltd | 印刷配線板用難燃性エポキシ樹脂組成物及びこれを用いたプリプレグ、金属箔張り積層板 |
US6281331B1 (en) | 1998-03-23 | 2001-08-28 | Trimeris, Inc. | Methods and compositions for peptide synthesis |
US6656906B1 (en) | 1998-05-20 | 2003-12-02 | Trimeris, Inc. | Hybrid polypeptides with enhanced pharmacokinetic properties |
US6258782B1 (en) | 1998-05-20 | 2001-07-10 | Trimeris, Inc. | Hybrid polypeptides with enhanced pharmacokinetic properties |
US6565874B1 (en) | 1998-10-28 | 2003-05-20 | Atrix Laboratories | Polymeric delivery formulations of leuprolide with improved efficacy |
US6143314A (en) | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
ATE443714T1 (de) | 1999-05-17 | 2009-10-15 | Conjuchem Biotechnologies Inc | Lang wirkende peptidinhibitoren der virusfusion mit körperzellen bei viralen infektionen |
US6541020B1 (en) | 1999-07-09 | 2003-04-01 | Trimeris, Inc. | Methods and compositions for administration of therapeutic reagents |
JP4361710B2 (ja) | 2000-04-19 | 2009-11-11 | ジェネンテック・インコーポレーテッド | 徐放製剤 |
US7318931B2 (en) | 2001-06-21 | 2008-01-15 | Genentech, Inc. | Sustained release formulation |
CN1100564C (zh) | 2001-08-29 | 2003-02-05 | 周根发 | 用于治疗hiv感染的药物、其组合物及其用途 |
US7045552B2 (en) | 2002-09-27 | 2006-05-16 | Trimeris, Inc. | Pharmaceutical composition for improved administration of HIV gp41-derived peptides, and its use in therapy |
KR20070006708A (ko) * | 2004-01-07 | 2007-01-11 | 트라이머리스 인코퍼레이티드 | HIV gp41 HR2-유래된 합성 펩티드 및 인간 면역결핍바이러스의 전염을 저해하는 치료에서 이들의 용도 |
WO2005089805A2 (en) | 2004-03-15 | 2005-09-29 | Nektar Therapeutics Al, Corporation | Polymer-based compositions and conjugates of hiv entry inhibitors |
CA2556032A1 (en) * | 2004-03-15 | 2005-09-29 | Trimeris, Inc. | Site-specific chemical modification of hiv gp41-derived peptides |
TWI341844B (en) | 2006-02-02 | 2011-05-11 | Trimeris Inc | Hiv fusion inhibitor peptides with improved biological properties |
-
2007
- 2007-02-02 TW TW096104190A patent/TWI341844B/zh not_active IP Right Cessation
- 2007-02-02 US US11/701,910 patent/US7456251B2/en active Active
- 2007-02-02 CA CA2651793A patent/CA2651793C/en not_active Expired - Fee Related
- 2007-02-02 WO PCT/US2007/002990 patent/WO2007097903A2/en active Application Filing
- 2007-02-02 CN CN200780011992.6A patent/CN101415723B/zh not_active Expired - Fee Related
- 2007-02-02 NZ NZ570300A patent/NZ570300A/en not_active IP Right Cessation
- 2007-02-02 ES ES07749903T patent/ES2381631T3/es active Active
- 2007-02-02 DK DK07749903.6T patent/DK1989220T3/da active
- 2007-02-02 AU AU2007218025A patent/AU2007218025A1/en not_active Abandoned
- 2007-02-02 PT PT07749903T patent/PT1989220E/pt unknown
- 2007-02-02 AR ARP070100450A patent/AR059300A1/es active IP Right Grant
- 2007-02-02 AT AT07749903T patent/ATE537183T1/de active
- 2007-02-02 JP JP2008553389A patent/JP4682251B2/ja not_active Expired - Fee Related
- 2007-02-02 EP EP07749903A patent/EP1989220B1/de active Active
-
2008
- 2008-10-20 US US12/254,259 patent/US8034899B2/en active Active
-
2011
- 2011-08-31 US US13/222,766 patent/US20120040891A1/en not_active Abandoned
-
2012
- 2012-03-14 CY CY20121100268T patent/CY1113115T1/el unknown
-
2017
- 2017-05-02 AR ARP170101125A patent/AR108277A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
CN101415723A (zh) | 2009-04-22 |
US8034899B2 (en) | 2011-10-11 |
EP1989220B1 (de) | 2011-12-14 |
EP1989220A4 (de) | 2009-05-06 |
ES2381631T3 (es) | 2012-05-30 |
US20090105143A1 (en) | 2009-04-23 |
TWI341844B (en) | 2011-05-11 |
NZ570300A (en) | 2011-08-26 |
DK1989220T3 (da) | 2012-04-02 |
US20120040891A1 (en) | 2012-02-16 |
CA2651793A1 (en) | 2007-08-30 |
CY1113115T1 (el) | 2016-04-13 |
EP1989220A2 (de) | 2008-11-12 |
WO2007097903A2 (en) | 2007-08-30 |
AR059300A1 (es) | 2008-03-26 |
US7456251B2 (en) | 2008-11-25 |
JP2009525051A (ja) | 2009-07-09 |
JP4682251B2 (ja) | 2011-05-11 |
AR108277A2 (es) | 2018-08-01 |
CN101415723B (zh) | 2014-06-25 |
WO2007097903A3 (en) | 2008-05-22 |
AU2007218025A1 (en) | 2007-08-30 |
PT1989220E (pt) | 2012-03-23 |
TW200806687A (en) | 2008-02-01 |
CA2651793C (en) | 2015-07-07 |
US20070179278A1 (en) | 2007-08-02 |
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