ATE530666T1 - Mikrobläschen zur affinitätstrennung - Google Patents

Mikrobläschen zur affinitätstrennung

Info

Publication number
ATE530666T1
ATE530666T1 AT05858304T AT05858304T ATE530666T1 AT E530666 T1 ATE530666 T1 AT E530666T1 AT 05858304 T AT05858304 T AT 05858304T AT 05858304 T AT05858304 T AT 05858304T AT E530666 T1 ATE530666 T1 AT E530666T1
Authority
AT
Austria
Prior art keywords
microbubbles
affinity
affinity separation
methods
coated
Prior art date
Application number
AT05858304T
Other languages
English (en)
Inventor
Thomas Adams
Edward Jablonski
Original Assignee
Iris Molecular Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iris Molecular Diagnostics Inc filed Critical Iris Molecular Diagnostics Inc
Application granted granted Critical
Publication of ATE530666T1 publication Critical patent/ATE530666T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545Synthetic resin
    • G01N33/546Synthetic resin as water suspendable particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545Synthetic resin
    • G01N33/547Synthetic resin with antigen or antibody attached to the carrier via a bridging agent
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552Glass or silica
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/76Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
    • G01N2333/765Serum albumin, e.g. HSA
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
AT05858304T 2004-11-03 2005-11-03 Mikrobläschen zur affinitätstrennung ATE530666T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62494804P 2004-11-03 2004-11-03
PCT/US2005/040162 WO2006137933A2 (en) 2004-11-03 2005-11-03 Microbubbles for affinity separation

Publications (1)

Publication Number Publication Date
ATE530666T1 true ATE530666T1 (de) 2011-11-15

Family

ID=37570908

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05858304T ATE530666T1 (de) 2004-11-03 2005-11-03 Mikrobläschen zur affinitätstrennung

Country Status (12)

Country Link
US (3) US8835186B2 (de)
EP (2) EP1815028B1 (de)
JP (2) JP5037350B2 (de)
KR (1) KR101281433B1 (de)
CN (2) CN103091485A (de)
AT (1) ATE530666T1 (de)
AU (1) AU2005333157B2 (de)
CA (1) CA2585675A1 (de)
DK (1) DK1815028T3 (de)
ES (2) ES2550177T3 (de)
PT (1) PT1815028E (de)
WO (1) WO2006137933A2 (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2550177T3 (es) 2004-11-03 2015-11-05 Iris Molecular Diagnostics, Inc. Microburbujas para concentración de afinidad
KR20070105967A (ko) 2004-11-03 2007-10-31 아이리스 몰레큘라 다이아그노스틱스, 인코오포레이티드 균질 분석물 탐지
CA2834432C (en) * 2011-05-23 2020-01-07 Sekisui Medical Co., Ltd. Method of inhibiting nonspecific reaction in pivka-ii assay reagent
US20140346113A1 (en) 2011-12-21 2014-11-27 3M Innovative Properties Company Bioseparation compositions and methods for making and using same
KR101462986B1 (ko) 2012-06-25 2014-11-19 대한민국 분변 중 요네균 신속분리를 위한 자석 나노입자를 이용한 검출방법
US20140288421A1 (en) * 2013-03-12 2014-09-25 The Regents Of The University Of California Gas vesicle ultrasound contrast agents and methods of using the same
CN105308437B (zh) 2013-03-15 2018-01-19 Hycor 生物医学有限责任公司 进行样本的冷光和荧光测量的装置和相关方法
US20150219636A1 (en) * 2014-01-28 2015-08-06 Targeson, Inc. Isolation of cells and biological substances using buoyant microbubbles
EP3142764B1 (de) 2014-05-10 2022-12-07 Diagnologix, LLC System und vorrichtung zur isolierung und anreicherung von wirkstoffen mittels flotation
US10195547B2 (en) 2014-12-15 2019-02-05 Akadeum Life Sciences, Inc. Method and system for buoyant separation
US11291931B2 (en) * 2014-12-15 2022-04-05 Akadeum Life Sciences, Inc. Method and system for buoyant separation
CN107614458B (zh) 2015-05-01 2021-05-11 百进生物科技公司 稳定的纳米磁性颗粒分散体
KR20190057444A (ko) 2015-08-10 2019-05-28 에센릭스 코프. 단계 간단화, 소량 샘플, 속도 가속화, 사용이 용이한 생물화학 측정장치 및 방법
JP6594528B2 (ja) 2015-09-14 2019-10-23 エッセンリックス コーポレーション 蒸気凝縮液、特に呼気凝縮液を採取し分析する装置及びシステム、並びにそれらの使用方法
EP3341728A4 (de) 2015-09-14 2019-04-17 Essenlix Corp. Vorrichtung und system zur analyse einer probe, insbesondere blut, sowie verfahren zu deren verwendung
AU2016381806B2 (en) * 2015-12-29 2021-04-15 Thermogenesis Corporation Cell separation devices, systems, and methods
WO2017190117A1 (en) * 2016-04-30 2017-11-02 BioLegend, Inc. Compositions and methods for performing magnetibuoyant separations
KR102381114B1 (ko) * 2016-10-06 2022-03-30 아이리스 인터내셔널 인크. 동적 포커스 시스템 및 방법들
EP3555267B1 (de) * 2016-12-16 2021-08-04 Diagnologix, LLC Auftriebsaktiviertes trennverfahren und vorrichtung
US10628693B2 (en) 2016-12-21 2020-04-21 Essenlix Corporation Devices and methods for authenticating a sample and use of the same
US11274996B2 (en) 2017-02-07 2022-03-15 Essenlix Corporation Compressed open flow assay and use
US11927560B2 (en) 2017-02-08 2024-03-12 Essenlix Corporation Bio/chemical material extraction and assay
CA3053132A1 (en) 2017-02-09 2018-08-16 Essenlix Corp. Assay with amplification
CN111433606A (zh) 2017-02-09 2020-07-17 Essenlix公司 采用不同间距高度的测定
EP3662259A4 (de) 2017-02-09 2021-08-25 Essenlix Corporation Kolorimetrische tests
JP7107953B2 (ja) 2017-02-16 2022-07-27 エッセンリックス コーポレーション テクスチャ表面を用いたアッセイ
US11280706B2 (en) 2017-08-01 2022-03-22 Essenlix Corporation Dilution calibration
US11243201B2 (en) 2017-08-01 2022-02-08 Essenlix Corporation Sample collection, holding and assaying
US11725227B2 (en) 2017-08-01 2023-08-15 Essenlix Corporation Devices and methods for examining drug effects on microorganisms
US11393561B2 (en) 2017-10-13 2022-07-19 Essenlix Corporation Devices and methods for authenticating a medical test and use of the same
US11609224B2 (en) 2017-10-26 2023-03-21 Essenlix Corporation Devices and methods for white blood cell analyses
US10807095B2 (en) 2017-10-26 2020-10-20 Essenlix Corporation Making and tracking assay card
US11237113B2 (en) 2017-10-26 2022-02-01 Essenlix Corporation Rapid pH measurement
WO2019118652A1 (en) 2017-12-12 2019-06-20 Essenlix Corporation Sample manipulation and assay with rapid temperature change
WO2019118936A2 (en) 2017-12-14 2019-06-20 Essenlix Corporation Devices, systems, and methods for monitoring hair
US11156606B2 (en) 2018-01-11 2021-10-26 Essenlix Corporation Homogeneous assay (II)
US11155575B2 (en) 2018-03-21 2021-10-26 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbent, devices and methods
US11350909B2 (en) 2018-04-17 2022-06-07 California Institute Of Technology Cross amplitude modulation ultrasound pulse sequence
CN112437692B (zh) 2018-07-09 2022-06-24 爱卡德姆生命科学公司 用于有浮力颗粒处理的***和方法
US11885952B2 (en) 2018-07-30 2024-01-30 Essenlix Corporation Optics, device, and system for assaying and imaging
CN109608679B (zh) * 2018-12-10 2021-09-21 天津工业大学 一种核孔复合体接枝聚合物仿生膜制备方法
CN110354523B (zh) * 2019-07-14 2024-02-06 河北龙亿环境工程有限公司 一种具有多微孔气泡罩的新型塔板
US20220334108A1 (en) * 2019-09-26 2022-10-20 3M Innovative Properties Company Compositions and methods of detecting analytes
US11819842B2 (en) 2021-08-26 2023-11-21 Akadeum Life Sciences, Inc. Method and system for buoyant separation
WO2023039400A1 (en) * 2021-09-07 2023-03-16 Triangle Biotechnology, Inc. Targeted nanodroplet and microbubble compositions and methods for enrichment, lysis, and extraction of microbial cells

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1582956A (en) * 1976-07-30 1981-01-21 Ici Ltd Composite magnetic particles
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
DE3100535A1 (de) 1981-01-10 1982-08-12 Dr. Karl Thomae Gmbh, 7950 Biberach "neue carbonsaeure-derivate, ihre herstellung und ihre verwendung als arzneimittel"
FR2571498B1 (fr) * 1984-10-04 1988-04-08 Immunotech Sa Procede de separation de cellules utilisant des anticorps et des billes de faible densite
US4618525A (en) * 1985-06-03 1986-10-21 Minnesota Mining And Manufacturing Company Coated glass microbubbles and article incorporating them
US4824776A (en) * 1985-07-25 1989-04-25 Molecular Biosystems, Inc. Method for increasing the sensitivity of nucleic acid hybridization assays
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4933447A (en) * 1987-09-24 1990-06-12 Ss Pharmaceutical Co., Ltd. Quinoline derivatives
US4957656A (en) * 1988-09-14 1990-09-18 Molecular Biosystems, Inc. Continuous sonication method for preparing protein encapsulated microbubbles
US5766849A (en) * 1989-07-11 1998-06-16 Gen-Probe Incorporated Methods of amplifying nucleic acids using promoter-containing primer sequence
SE9002480D0 (sv) * 1990-07-23 1990-07-23 Hans Lilja Assay of free and complexed prostate-specific antigen
EP0488152A3 (en) 1990-11-30 1992-11-25 Hitachi, Ltd. Method for immunoassay and apparatus therefor
WO1992015708A1 (en) * 1991-02-27 1992-09-17 Amoco Corporation Methods for improving the sensitivity of hybridization assays
IE920778A1 (en) 1991-03-12 1992-09-23 Du Pont Method for specific binding assays using a releasable ligand
US5665539A (en) * 1991-07-12 1997-09-09 The Regents Of The University Of California Immuno-polymerase chain reaction system for antigen detection
US6723303B1 (en) * 1991-09-17 2004-04-20 Amersham Health, As Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane
ATE239484T1 (de) 1991-10-24 2003-05-15 Isis Pharmaceuticals Inc Derivatisierte oligonukleotide mit verbessertem aufnahmevermögen
US5270184A (en) * 1991-11-19 1993-12-14 Becton, Dickinson And Company Nucleic acid target generation
US6172208B1 (en) * 1992-07-06 2001-01-09 Genzyme Corporation Oligonucleotides modified with conjugate groups
DE4232755A1 (de) 1992-09-26 1994-03-31 Schering Ag Mikropartikelpräparationen aus biologisch abbaubaren Mischpolymeren
WO1994016108A1 (en) * 1993-01-15 1994-07-21 The Public Health Research Institute Of The City Of New York, Inc. Sensitive nucleic acid sandwich hybridization assays and kits
US5985548A (en) * 1993-02-04 1999-11-16 E. I. Du Pont De Nemours And Company Amplification of assay reporters by nucleic acid replication
WO1994027150A1 (en) * 1993-05-10 1994-11-24 Nissui Pharmaceutical Co., Ltd. Method for assaying more than one immunological ligand, and assay reagent and kit therefor
US5635602A (en) * 1993-08-13 1997-06-03 The Regents Of The University Of California Design and synthesis of bispecific DNA-antibody conjugates
US5599677A (en) * 1993-12-29 1997-02-04 Abbott Laboratories Immunoassays for prostate specific antigen
US5648213A (en) * 1994-08-30 1997-07-15 Beckman Instruments, Inc. Compositions and methods for use in detection of analytes
JPH08178926A (ja) * 1994-10-25 1996-07-12 Sumitomo Pharmaceut Co Ltd イムノアッセイプレートおよびその用途
BR9509673A (pt) 1994-11-15 1997-09-30 Upjohn Co Compostos e uso dos mesmos
SE504798C2 (sv) 1995-06-16 1997-04-28 Ulf Landegren Immunanalys och testkit med två reagens som kan tvärbindas om de adsorberats till analyten
DE19524133A1 (de) * 1995-07-03 1997-01-09 Bayer Ag Die Verwendung von neuen und bekannten kationischen 4,5-Dihydro-1H-1,2,3-triazoliumverbindungen als Farbstoffe, neue kationische 4,5-Dihydro-1H-1,2,3-triazoliumverbindungen und deren Herstellung
NO301198B1 (no) 1995-07-14 1997-09-22 Alcatel Kabel Norge As Kabel, fremgangsmåte og impregneringsmasse
AT403803B (de) 1996-04-19 1998-05-25 Sanochemia Ltd Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln
US6165942A (en) 1996-10-03 2000-12-26 Nissan Chemical Industries, Ltd. Heterocycle-fused pyrimidinone derivative and herbicidal composition
US6083484A (en) * 1996-10-17 2000-07-04 Molecular Biosystems, Inc. Microparticles stabilized by polynuclear chromium complexes and their use as ultrasound contrast agents
US6245318B1 (en) 1997-05-27 2001-06-12 Mallinckrodt Inc. Selectively binding ultrasound contrast agents
US6086540A (en) * 1997-10-07 2000-07-11 Molecular Biosystems, Inc. Methods of ultrasound imaging using echogenically persistent contrast agents
US6531278B1 (en) * 1998-01-14 2003-03-11 Utah State University Ligand-DNA composition for capture and detection of contaminants on a solid surface
JP2002512886A (ja) * 1998-04-28 2002-05-08 ニユコメド・イメージング・アクシエセルカペト 分離方法におけるまたはこれに関する改良
US8063190B2 (en) * 1998-06-02 2011-11-22 Tom Robin Caine Boyde Nucleic acid-linked conjugates and methods for making and using them
US6214566B1 (en) * 1998-11-16 2001-04-10 The Administrators Of The Tulane Educational Fund Method for detecting anti-squalene antibodies
EP1149175A2 (de) 1999-01-11 2001-10-31 President And Fellows Of Harvard College Isothermische dns-amplifizierung
ATE312350T1 (de) * 1999-10-13 2005-12-15 Univ British Columbia Verfahren zur identifizierung von verbindungen, die die neuronale aktivität modulieren
CA2391534A1 (en) * 1999-11-15 2001-05-25 Drug Innovation & Design, Inc. Selective cellular targeting: multifunctional delivery vehicles
US7306904B2 (en) * 2000-02-18 2007-12-11 Olink Ab Methods and kits for proximity probing
US6511809B2 (en) * 2000-06-13 2003-01-28 E. I. Du Pont De Nemours And Company Method for the detection of an analyte by means of a nucleic acid reporter
US7439016B1 (en) 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
WO2002068695A2 (en) 2001-02-22 2002-09-06 Arcturus Engineering, Inc. Quantitative immunohistochemistry (qihc)
WO2002083951A1 (en) 2001-04-10 2002-10-24 Northeastern University Multiplexed ligand/protein binding assays with pna labels
EP1249500A1 (de) 2001-04-12 2002-10-16 chimera biotec GmbH Verfahren zum Nachweis einer Substanz
US6670386B2 (en) 2001-07-31 2003-12-30 Bristol-Myers Squibb Company Bicyclic modulators of androgen receptor function
EA006965B1 (ru) 2002-03-08 2006-06-30 Айдгенёссише Текнише Хохшуле Цюрих Закодированные самособирающиеся химические библиотеки
JP4836451B2 (ja) * 2002-07-18 2011-12-14 メルス ベー ヴェー 抗体混合物の組換え生産
NZ538713A (en) 2002-08-12 2007-01-26 Takeda Chemical Industries Ltd Fused benzene derivative and use
WO2004042030A2 (en) 2002-11-01 2004-05-21 Leucadia Technologies, Inc. Displacement sandwich immuno-pcr
WO2006012356A2 (en) 2004-06-23 2006-02-02 Washington University Methods for determining risk of developing regular smoking behavior
TW200624427A (en) 2004-09-20 2006-07-16 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
ES2550177T3 (es) 2004-11-03 2015-11-05 Iris Molecular Diagnostics, Inc. Microburbujas para concentración de afinidad
KR20070105967A (ko) * 2004-11-03 2007-10-31 아이리스 몰레큘라 다이아그노스틱스, 인코오포레이티드 균질 분석물 탐지
AU2009215799B2 (en) 2008-02-21 2013-08-22 Iris International Inc. Method for early determination of recurrence after therapy for prostate cancer

Also Published As

Publication number Publication date
PT1815028E (pt) 2012-01-24
WO2006137933A3 (en) 2007-05-03
CN101065497B (zh) 2012-11-21
US8513032B2 (en) 2013-08-20
ES2376578T3 (es) 2012-03-15
CN103091485A (zh) 2013-05-08
AU2005333157A1 (en) 2006-12-28
KR101281433B1 (ko) 2013-07-02
EP2302078A1 (de) 2011-03-30
WO2006137933A2 (en) 2006-12-28
AU2005333157B2 (en) 2011-06-30
JP2012197281A (ja) 2012-10-18
EP2302078B1 (de) 2015-07-15
CA2585675A1 (en) 2006-12-28
US20090176201A1 (en) 2009-07-09
JP5037350B2 (ja) 2012-09-26
ES2550177T3 (es) 2015-11-05
EP1815028A2 (de) 2007-08-08
US8835186B2 (en) 2014-09-16
EP1815028A4 (de) 2008-09-10
JP2008518973A (ja) 2008-06-05
KR20070110484A (ko) 2007-11-19
CN101065497A (zh) 2007-10-31
DK1815028T3 (da) 2012-01-30
US20110230644A1 (en) 2011-09-22
US20110236884A1 (en) 2011-09-29
EP1815028B1 (de) 2011-10-26

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