ATE529742T1 - Siva-ubiquitinierung und/oder -abbau verbundene aktivität und modulatoren davon - Google Patents
Siva-ubiquitinierung und/oder -abbau verbundene aktivität und modulatoren davonInfo
- Publication number
- ATE529742T1 ATE529742T1 AT07700742T AT07700742T ATE529742T1 AT E529742 T1 ATE529742 T1 AT E529742T1 AT 07700742 T AT07700742 T AT 07700742T AT 07700742 T AT07700742 T AT 07700742T AT E529742 T1 ATE529742 T1 AT E529742T1
- Authority
- AT
- Austria
- Prior art keywords
- ubiquitination
- siva
- modulators
- associated activity
- degradation associated
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/9015—Ligases (6)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL173104A IL173104A0 (en) | 2006-01-12 | 2006-01-12 | Siva and ubiquintination |
PCT/IL2007/000050 WO2007080593A2 (en) | 2006-01-12 | 2007-01-11 | Siva ubiquitination and/or degradation-related activity and modulators thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE529742T1 true ATE529742T1 (de) | 2011-11-15 |
Family
ID=38008295
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07700742T ATE529742T1 (de) | 2006-01-12 | 2007-01-11 | Siva-ubiquitinierung und/oder -abbau verbundene aktivität und modulatoren davon |
Country Status (9)
Country | Link |
---|---|
US (1) | US8273545B2 (de) |
EP (1) | EP1977239B1 (de) |
JP (1) | JP5086273B2 (de) |
AT (1) | ATE529742T1 (de) |
AU (1) | AU2007205694B2 (de) |
CA (1) | CA2637412A1 (de) |
ES (1) | ES2373986T3 (de) |
IL (2) | IL173104A0 (de) |
WO (1) | WO2007080593A2 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL189405A0 (en) * | 2008-02-10 | 2008-12-29 | Yeda Res & Dev | Stabilization of siva2 |
IL189408A0 (en) | 2008-02-10 | 2009-02-11 | Yeda Res & Dev | Siva3, its preparation and pharmaceutical compositions containing it |
EP2551670A1 (de) * | 2011-07-27 | 2013-01-30 | Merck Patent GmbH | Zellenbasierte NIK-Hemmeranalyse |
US10709434B2 (en) * | 2013-07-09 | 2020-07-14 | Globus Medical, Inc. | Surgical access systems and methods |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
GB8615942D0 (en) | 1986-06-30 | 1986-08-06 | Animal & Food Research Council | Peptide production |
EP0279582A3 (de) | 1987-02-17 | 1989-10-18 | Pharming B.V. | DNA-Sequenzen die Proteine zwecks effizienter Abscheidung zur Milchdrüse leiten |
US4873316A (en) | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
GB8826446D0 (en) | 1988-11-11 | 1988-12-14 | Agricultural & Food Res | Peptide production |
US5108921A (en) | 1989-04-03 | 1992-04-28 | Purdue Research Foundation | Method for enhanced transmembrane transport of exogenous molecules |
US5073964A (en) | 1989-08-04 | 1991-12-17 | Aware, Inc. | Signal processing device and method |
AU1228592A (en) | 1991-01-11 | 1992-08-17 | American Red Cross | Expression of active human protein c in mammary tissue of transgenic animals |
DE69230789T3 (de) | 1991-01-18 | 2007-10-31 | Amgen Inc., Thousand Oaks | Methoden zur behandlung von durch den tumor nekrose faktor ausgelösten krankheiten |
UA71889C2 (uk) * | 1996-04-02 | 2005-01-17 | Йєда Рісерч Енд Дівелопмент Ко. Лтд. | Модулятори зв'язаного з рецептором tnf фактора (traf), їх одержання та застосування |
US6010853A (en) * | 1997-05-29 | 2000-01-04 | Dana-Farber Cancer Institute | Siva genes, novel genes involved in CD27-mediated apoptosis |
US5843721A (en) * | 1997-07-03 | 1998-12-01 | Tularik Inc. | Nucleic acids encoding human NIK protein |
WO2005043119A2 (en) * | 2003-10-28 | 2005-05-12 | Rigel Pharmaceuticals, Inc. | Methods and compositions for the identification of anti-poxvirus agents |
US8034340B2 (en) * | 2003-11-30 | 2011-10-11 | Yeda Research And Development Ltd. | Method for treating an immune disorder by decreasing NIK-SIVA complex formation |
-
2006
- 2006-01-12 IL IL173104A patent/IL173104A0/en unknown
-
2007
- 2007-01-11 ES ES07700742T patent/ES2373986T3/es active Active
- 2007-01-11 CA CA002637412A patent/CA2637412A1/en not_active Abandoned
- 2007-01-11 WO PCT/IL2007/000050 patent/WO2007080593A2/en active Application Filing
- 2007-01-11 US US12/160,627 patent/US8273545B2/en not_active Expired - Fee Related
- 2007-01-11 EP EP07700742A patent/EP1977239B1/de not_active Not-in-force
- 2007-01-11 AT AT07700742T patent/ATE529742T1/de not_active IP Right Cessation
- 2007-01-11 JP JP2008549987A patent/JP5086273B2/ja not_active Expired - Fee Related
- 2007-01-11 AU AU2007205694A patent/AU2007205694B2/en not_active Ceased
-
2008
- 2008-06-24 IL IL192414A patent/IL192414A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1977239A2 (de) | 2008-10-08 |
US8273545B2 (en) | 2012-09-25 |
IL173104A0 (en) | 2006-06-11 |
ES2373986T3 (es) | 2012-02-10 |
EP1977239B1 (de) | 2011-10-19 |
US20100204091A1 (en) | 2010-08-12 |
IL192414A0 (en) | 2008-12-29 |
JP2009523023A (ja) | 2009-06-18 |
CA2637412A1 (en) | 2007-07-19 |
JP5086273B2 (ja) | 2012-11-28 |
WO2007080593A2 (en) | 2007-07-19 |
AU2007205694B2 (en) | 2013-06-06 |
WO2007080593A3 (en) | 2007-11-15 |
IL192414A (en) | 2013-07-31 |
AU2007205694A1 (en) | 2007-07-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |