ATE523206T1 - Anthrax-impfstoff - Google Patents

Anthrax-impfstoff

Info

Publication number
ATE523206T1
ATE523206T1 AT07852377T AT07852377T ATE523206T1 AT E523206 T1 ATE523206 T1 AT E523206T1 AT 07852377 T AT07852377 T AT 07852377T AT 07852377 T AT07852377 T AT 07852377T AT E523206 T1 ATE523206 T1 AT E523206T1
Authority
AT
Austria
Prior art keywords
protective antigen
anthrax vaccine
bacillus anthracis
optimized
anthracis protective
Prior art date
Application number
AT07852377T
Other languages
English (en)
Inventor
Lada Rasochova
Philip Dao
Jamie Phelps
Original Assignee
Pfenex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfenex Inc filed Critical Pfenex Inc
Application granted granted Critical
Publication of ATE523206T1 publication Critical patent/ATE523206T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT07852377T 2006-05-30 2007-05-30 Anthrax-impfstoff ATE523206T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80953606P 2006-05-30 2006-05-30
PCT/US2007/012842 WO2008027099A2 (en) 2006-05-30 2007-05-30 Rpa optimization

Publications (1)

Publication Number Publication Date
ATE523206T1 true ATE523206T1 (de) 2011-09-15

Family

ID=39136419

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07852377T ATE523206T1 (de) 2006-05-30 2007-05-30 Anthrax-impfstoff

Country Status (5)

Country Link
US (1) US8569015B2 (de)
EP (2) EP2363495B1 (de)
CN (1) CN101495644B (de)
AT (1) ATE523206T1 (de)
WO (1) WO2008027099A2 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
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EP2363495B1 (de) 2006-05-30 2019-07-24 Pfenex Inc. Anthrax-Impfstoff
US8153391B2 (en) 2008-08-29 2012-04-10 Bunge Oils, Inc. Hydrolases, nucleic acids encoding them and methods for making and using them
US8198062B2 (en) 2008-08-29 2012-06-12 Dsm Ip Assets B.V. Hydrolases, nucleic acids encoding them and methods for making and using them
US8357503B2 (en) 2008-08-29 2013-01-22 Bunge Oils, Inc. Hydrolases, nucleic acids encoding them and methods for making and using them
UA106885C2 (uk) 2009-04-17 2014-10-27 Дау Агросайансіз Елелсі Dig-3 інсектицидні cry-токсини
UA111708C2 (uk) 2009-10-16 2016-06-10 Бандж Ойлз, Інк. Спосіб рафінування олії
UA109884C2 (uk) 2009-10-16 2015-10-26 Поліпептид, що має активність ферменту фосфатидилінозитол-специфічної фосфоліпази с, нуклеїнова кислота, що його кодує, та спосіб його виробництва і застосування
US20110110968A1 (en) * 2009-11-12 2011-05-12 Stanley Goldman Human optimized Bacillus anthracis protective antigen
JP2013514769A (ja) 2009-12-16 2013-05-02 ダウ アグロサイエンシィズ エルエルシー 害虫抵抗性管理のためのＣＲＹ１ＣａおよびＣＲＹ１Ｆａタンパク質の併用
RU2582249C2 (ru) 2010-04-23 2016-04-20 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи КОМБИНАЦИИ, ВКЛЮЧАЮЩИЕ БЕЛКИ Cry34Ab/35Ab И Cry3Aa, ДЛЯ ПРЕДОТВРАЩЕНИЯ РАЗВИТИЯ УСТОЙЧИВОСТИ У КУКУРУЗНЫХ КОРНЕВЫХ ЖУКОВ (Diabrotica spp.)
US9234208B1 (en) 2010-05-10 2016-01-12 Dow Agrosciences Llc DIG-13 insecticidal cry toxins
AR084293A1 (es) 2010-12-16 2013-05-08 Dow Agrosciences Llc Cry1FA RADIOMARCADA, BIOLOGICAMENTE ACTIVA Y METODOS DE ENSAYOS DE UNION AL RECEPTOR
US10017754B2 (en) 2012-03-30 2018-07-10 Basf Enzymes Llc Gene encoding cellulase
CN102864141A (zh) * 2012-09-13 2013-01-09 成都生物制品研究所有限责任公司 一种构建大容量同义密码库及优化基因模板的方法
WO2014134187A1 (en) * 2013-02-26 2014-09-04 The Regents Of The University Of California Compositions and methods for the treatment of cancer
GB201308828D0 (en) 2013-03-12 2013-07-03 Verenium Corp Phytase
GB201308853D0 (en) 2013-03-12 2013-07-03 Verenium Corp Genes encoding xylanase
KR101446054B1 (ko) * 2013-03-14 2014-10-01 전남대학교산학협력단 재조합 단백질의 과발현을 위한 번역속도 조절용 램프 태그 및 이용
GB201308843D0 (en) 2013-03-14 2013-07-03 Verenium Corp Phytase formulation
BR112015032838A2 (pt) 2013-07-25 2017-11-07 Basf Enzymes Llc fitase
AR099800A1 (es) 2014-03-21 2016-08-17 Agrigenetics Inc Cry1d para controlar el gusano de la mazorca del maíz
NZ726117A (en) 2014-06-20 2017-10-27 Dow Agrosciences Llc Vegetative insecticidal proteins useful for control of insect pests
EP3227455B1 (de) 2014-12-01 2023-07-12 Pfenex Inc. Fusionspartner zur herstellung von peptiden
MX2017008413A (es) 2014-12-30 2017-10-19 Dow Agrosciences Llc Toxinas cry1ca modificadas utiles para el control de plagas de insectos.
CA3038972A1 (en) 2016-09-30 2018-04-05 Dow Agrosciences Llc Binary insecticidal cry toxins
BR112020005972A2 (pt) 2017-09-26 2020-11-17 Bunge Global Innovation, Llc remoção enzimática de substratos de clorofila de óleos à base de triacilglicerol
CN108363904B (zh) * 2018-02-07 2019-06-28 南京林业大学 一种用于木本植物遗传密码子优化的CodonNX***及其优化方法
BR112021018929A2 (pt) 2019-03-27 2021-11-30 Bunge Global Innovation Llc Tratamento de sílica adsorvente para remoção de derivados de clorofila a partir de óleos à base de triacilglicerol
CN111951891B (zh) * 2019-05-16 2022-11-01 清华大学 确定优化的核苷酸序列的方法和***
CN111926040B (zh) * 2020-10-12 2021-01-26 天津中逸安健生物科技有限公司 一种新型冠状病毒rbd核苷酸序列、优化方法与应用
WO2023026292A1 (en) * 2021-08-25 2023-03-02 Ramot At Tel-Aviv University Ltd. Optimized expression in target organisms

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US6770479B1 (en) * 1998-07-10 2004-08-03 The United States Of America As Represented By The Secretary Of The Army Anthrax vaccine
US6924365B1 (en) * 1998-09-29 2005-08-02 Transkaryotic Therapies, Inc. Optimized messenger RNA
DE10037111A1 (de) 2000-07-27 2002-02-07 Boehringer Ingelheim Int Herstellung eines rekombinanten Proteins in einer prokaryontischen Wirtszelle
AT500850B1 (de) * 2000-12-26 2007-10-15 Monsanto Technology Llc Rekombinante dna-vektoren zur expression von somatotropinen
US7261900B2 (en) * 2002-08-09 2007-08-28 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Recombinant modified Bacillus anthracis protective antigen for use in vaccines
WO2005034841A2 (en) 2003-05-14 2005-04-21 Merck & Co., Inc. Anthrax vaccine
CA2547511A1 (en) * 2003-12-01 2005-07-28 Dow Global Technolgies Inc. Recombinant icosahedral virus like particle production in pseudomonads
EP2363495B1 (de) 2006-05-30 2019-07-24 Pfenex Inc. Anthrax-Impfstoff

Also Published As

Publication number Publication date
EP2363495A1 (de) 2011-09-07
EP2021490B1 (de) 2011-09-07
CN101495644A (zh) 2009-07-29
US8569015B2 (en) 2013-10-29
WO2008027099A3 (en) 2008-12-18
WO2008027099A9 (en) 2008-04-24
US20080058262A1 (en) 2008-03-06
EP2021490A2 (de) 2009-02-11
EP2363495B1 (de) 2019-07-24
WO2008027099A2 (en) 2008-03-06
CN101495644B (zh) 2012-11-07

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