ATE506370T1 - Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen - Google Patents

Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen

Info

Publication number
ATE506370T1
ATE506370T1 AT04743057T AT04743057T ATE506370T1 AT E506370 T1 ATE506370 T1 AT E506370T1 AT 04743057 T AT04743057 T AT 04743057T AT 04743057 T AT04743057 T AT 04743057T AT E506370 T1 ATE506370 T1 AT E506370T1
Authority
AT
Austria
Prior art keywords
reagents
proteins
methods
disulfide bonds
glycosylation
Prior art date
Application number
AT04743057T
Other languages
English (en)
Inventor
Benjamin Davis
David Gamblin
Anthony Fairbanks
Philippe Garnier
Original Assignee
Isis Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0314743A external-priority patent/GB0314743D0/en
Priority claimed from GB0328884A external-priority patent/GB0328884D0/en
Application filed by Isis Innovation filed Critical Isis Innovation
Application granted granted Critical
Publication of ATE506370T1 publication Critical patent/ATE506370T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/14Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/08Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium
    • C07H5/10Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium to sulfur
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT04743057T 2003-06-24 2004-06-24 Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen ATE506370T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0314743A GB0314743D0 (en) 2003-06-24 2003-06-24 Reagents and methods
GB0328884A GB0328884D0 (en) 2003-12-12 2003-12-12 Methods
PCT/GB2004/002706 WO2005000862A2 (en) 2003-06-24 2004-06-24 Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins

Publications (1)

Publication Number Publication Date
ATE506370T1 true ATE506370T1 (de) 2011-05-15

Family

ID=33554162

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04743057T ATE506370T1 (de) 2003-06-24 2004-06-24 Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen

Country Status (13)

Country Link
US (1) US8637578B2 (de)
EP (1) EP1644390B1 (de)
JP (1) JP4787155B2 (de)
KR (1) KR20060019611A (de)
AT (1) ATE506370T1 (de)
AU (1) AU2004251105B2 (de)
BR (1) BRPI0411766A (de)
CA (1) CA2529341A1 (de)
DE (1) DE602004032345D1 (de)
EA (1) EA011299B1 (de)
IL (1) IL172729A0 (de)
NZ (1) NZ544654A (de)
WO (1) WO2005000862A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0507123D0 (en) * 2005-04-08 2005-05-11 Isis Innovation Method
CN1299603C (zh) * 2005-07-01 2007-02-14 浙江大学 糖基化谷类蛋白质-硒元素复合物制备方法
GB0602352D0 (en) * 2006-02-06 2006-03-15 Glycoform Ltd Glycoconjugation
EP2291349A2 (de) 2008-04-14 2011-03-09 The Board of Regents of The University of Texas System Niedermolekulare inhibitoren der pleckstrin-homologie-domäne und verfahren zu deren anwendung
EP2598638A2 (de) 2010-07-30 2013-06-05 Glycode Künstliches hefechromosom als träger des säuger-glycosylierungssignaleweges
WO2012127045A1 (en) 2011-03-23 2012-09-27 Glycode A yeast recombinant cell capable of producing gdp-fucose
AU2013358876B2 (en) 2012-12-14 2018-05-10 Phusis Therapeutics, Inc. Methods and compositions for inhibiting CNKSR1
US11203776B2 (en) 2014-11-12 2021-12-21 Tumorend, Llc Compositions, methods and treatments for inhibiting cell adhesion and virus binding and penetration
CA2983260C (en) 2015-04-20 2024-01-23 Phusis Therapeutics, Inc. Sulfonamide compounds, compositions and methods for inhibiting cnksr1
US11931428B2 (en) * 2019-08-23 2024-03-19 Wake Forest University Health Sciences Selective hydrogen sulfide probe and uses thereof
CN112979509B (zh) * 2021-03-10 2022-04-22 江西师范大学 一种三氟甲磺酰基炔酰胺类化合物及其制备方法和用途
WO2024050809A1 (zh) * 2022-09-09 2024-03-14 四川大学 一种蛋白和/或多肽糖基化修饰的方法
EP4346356A1 (de) 2022-09-29 2024-04-03 Novaled GmbH Halbleitermaterial, verfahren zur herstellung einer schicht des halbleitermaterials, organische halbleitervorrichtung mit dem halbleitermaterial und verbindung
EP4391765A1 (de) 2022-12-23 2024-06-26 Novaled GmbH Organische lichtemittierende diode, anzeigevorrichtung damit und verbindung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61205249A (ja) 1985-03-08 1986-09-11 Wako Pure Chem Ind Ltd 有機スルフイン酸塩の新規製法
EP0256486B1 (de) 1986-08-13 1990-12-05 Seitetsu Kagaku Co. Ltd. Verfahren zur Herstellung von Alkalimetallbenzolsulfinaten
ATE193551T1 (de) * 1991-03-18 2000-06-15 Scripps Research Inst Oligosaccharide als enzymsubstrate und - inhibitoren: verfahren und zusammensetzungen
CA2072763C (en) 1992-06-29 1994-05-17 Omar Chaudhry Process for the preparation of disulfides from thiols
IL123771A (en) * 1995-09-28 2002-11-10 Redox Pharma Corp Metal complexes as cysteine protease inhibitors
WO2000001712A2 (en) * 1998-07-02 2000-01-13 Genencor International, Inc. Chemically modified proteins with a carbohydrate moiety
CA2368213C (en) * 1999-04-28 2013-08-06 Genencor International, Inc. Specifically targeted catalytic antagonists and uses thereof
US6627744B2 (en) * 1999-07-02 2003-09-30 Genencor International, Inc. Synthesis of glycodendrimer reagents

Also Published As

Publication number Publication date
IL172729A0 (en) 2006-04-10
EA011299B1 (ru) 2009-02-27
CA2529341A1 (en) 2005-01-06
US8637578B2 (en) 2014-01-28
KR20060019611A (ko) 2006-03-03
JP4787155B2 (ja) 2011-10-05
EA200600042A1 (ru) 2006-08-25
BRPI0411766A (pt) 2006-08-08
NZ544654A (en) 2009-05-31
US20070213506A1 (en) 2007-09-13
DE602004032345D1 (de) 2011-06-01
AU2004251105B2 (en) 2010-04-01
EP1644390A2 (de) 2006-04-12
JP2007527376A (ja) 2007-09-27
EP1644390B1 (de) 2011-04-20
WO2005000862A3 (en) 2005-08-18
WO2005000862A2 (en) 2005-01-06
AU2004251105A1 (en) 2005-01-06

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