ATE489101T1 - Wiederherstellung der gelenken mit mesenchymalen stammzellen - Google Patents
Wiederherstellung der gelenken mit mesenchymalen stammzellenInfo
- Publication number
- ATE489101T1 ATE489101T1 AT01930730T AT01930730T ATE489101T1 AT E489101 T1 ATE489101 T1 AT E489101T1 AT 01930730 T AT01930730 T AT 01930730T AT 01930730 T AT01930730 T AT 01930730T AT E489101 T1 ATE489101 T1 AT E489101T1
- Authority
- AT
- Austria
- Prior art keywords
- stem cells
- mesenchymal stem
- joint
- joint restoration
- restoration
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30756—Cartilage endoprostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
- A61F2/3872—Meniscus for implantation between the natural bone surfaces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Developmental Biology & Embryology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19954900P | 2000-04-25 | 2000-04-25 | |
US23610600P | 2000-09-28 | 2000-09-28 | |
PCT/US2001/013267 WO2001080865A2 (en) | 2000-04-25 | 2001-04-24 | Joint repair using mesenchymal stem cells |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE489101T1 true ATE489101T1 (de) | 2010-12-15 |
Family
ID=26894885
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01930730T ATE489101T1 (de) | 2000-04-25 | 2001-04-24 | Wiederherstellung der gelenken mit mesenchymalen stammzellen |
Country Status (10)
Country | Link |
---|---|
US (5) | US20020005205A1 (de) |
EP (1) | EP1276486B2 (de) |
JP (4) | JP5090604B2 (de) |
AT (1) | ATE489101T1 (de) |
AU (2) | AU2001257236B2 (de) |
CA (1) | CA2405345C (de) |
DE (1) | DE60143517D1 (de) |
ES (1) | ES2353061T5 (de) |
PT (1) | PT1276486E (de) |
WO (1) | WO2001080865A2 (de) |
Families Citing this family (66)
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AU2001257236B2 (en) * | 2000-04-25 | 2006-03-09 | Mesoblast International Sarl | Joint repair using mesenchymal stem cells |
DE10139783C1 (de) * | 2001-08-14 | 2003-04-17 | Transtissue Technologies Gmbh | Zellzusammensetzungen zur Behandlung von Osteoarthrose, sowie Verfahren zu deren Herstellung |
CA2468335C (en) * | 2001-12-07 | 2014-07-08 | Geron Corporation | Chondrocyte precursors derived from human embryonic stem cells |
AR047712A1 (es) * | 2002-09-07 | 2006-02-15 | Royal Veterinary College | Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas |
JP2007508018A (ja) * | 2003-10-08 | 2007-04-05 | べト−ステム インコーポレイテッド | 新規の幹細胞組成物の調製法および使用法、ならびにこの組成物を含有するキット |
US8012693B2 (en) | 2003-12-16 | 2011-09-06 | 3M Innovative Properties Company | Analysis of chemically crosslinked cellular samples |
ES2657382T5 (es) * | 2004-03-22 | 2021-07-12 | Mesoblast Int Sarl | Células madre mesenquimales y usos de las mismas |
EP2298863B1 (de) | 2004-03-22 | 2015-07-22 | Mesoblast International Sàrl | Mesenchymale Stammzellen und deren Verwendungen |
AU2012205269B2 (en) * | 2004-03-22 | 2015-08-27 | Mesoblast International Sarl | Mesenchymal stem cells and uses therefor |
AU2015252160A1 (en) * | 2004-03-22 | 2015-11-26 | Mesoblast International Sarl | Mesenchymal stem cells and uses therefor |
US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
JP2008547005A (ja) * | 2005-06-16 | 2008-12-25 | スリーエム イノベイティブ プロパティズ カンパニー | マススペクトルを用いた化学的に架橋された細胞サンプルの分類方法 |
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EP2257289B1 (de) * | 2008-02-15 | 2018-09-19 | Bone Therapeutics | Pharmazeutische zusammensetzung zur behandlung oder verhinderung von knochengelenkserkrankungen |
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WO1999046366A1 (en) * | 1998-03-13 | 1999-09-16 | Osiris Therapeutics, Inc. | Uses for humane non-autologous mesenchymal stem cells |
IT1299488B1 (it) * | 1998-06-01 | 2000-03-16 | Afatec S R L | Tubo corrugato bimetallico e procedimento per la sua realizzazione |
JP2002536386A (ja) * | 1999-02-12 | 2002-10-29 | コラジェネシス インク. | 細胞または治療薬の送達のためのコラーゲンベースの注射システム |
US6716616B1 (en) * | 1999-09-28 | 2004-04-06 | Lexicon Genetics Incorporated | Human kinase proteins and polynucleotides encoding the same |
AU2001257236B2 (en) * | 2000-04-25 | 2006-03-09 | Mesoblast International Sarl | Joint repair using mesenchymal stem cells |
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2001
- 2001-04-24 AU AU2001257236A patent/AU2001257236B2/en not_active Expired
- 2001-04-24 PT PT01930730T patent/PT1276486E/pt unknown
- 2001-04-24 US US09/841,413 patent/US20020005205A1/en not_active Abandoned
- 2001-04-24 CA CA2405345A patent/CA2405345C/en not_active Expired - Lifetime
- 2001-04-24 EP EP01930730.5A patent/EP1276486B2/de not_active Expired - Lifetime
- 2001-04-24 JP JP2001577964A patent/JP5090604B2/ja not_active Expired - Lifetime
- 2001-04-24 WO PCT/US2001/013267 patent/WO2001080865A2/en active Application Filing
- 2001-04-24 DE DE60143517T patent/DE60143517D1/de not_active Expired - Lifetime
- 2001-04-24 ES ES01930730.5T patent/ES2353061T5/es not_active Expired - Lifetime
- 2001-04-24 AU AU5723601A patent/AU5723601A/xx active Pending
- 2001-04-24 AT AT01930730T patent/ATE489101T1/de not_active IP Right Cessation
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2008
- 2008-06-03 US US12/132,290 patent/US20090041730A1/en not_active Abandoned
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2012
- 2012-02-22 US US13/402,444 patent/US20120148548A1/en not_active Abandoned
- 2012-06-22 JP JP2012141003A patent/JP5792686B2/ja not_active Expired - Lifetime
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2013
- 2013-01-16 US US13/743,004 patent/US9050178B2/en not_active Expired - Fee Related
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2015
- 2015-02-25 JP JP2015035361A patent/JP2015128633A/ja active Pending
- 2015-04-16 US US14/687,963 patent/US9814580B2/en not_active Expired - Fee Related
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Also Published As
Publication number | Publication date |
---|---|
CA2405345C (en) | 2012-09-18 |
ES2353061T5 (es) | 2014-04-07 |
US9050178B2 (en) | 2015-06-09 |
JP6382262B2 (ja) | 2018-08-29 |
US20020005205A1 (en) | 2002-01-17 |
JP2015128633A (ja) | 2015-07-16 |
JP2012210437A (ja) | 2012-11-01 |
EP1276486B1 (de) | 2010-11-24 |
JP2016216487A (ja) | 2016-12-22 |
WO2001080865A9 (en) | 2002-12-27 |
AU5723601A (en) | 2001-11-07 |
US20150216904A1 (en) | 2015-08-06 |
CA2405345A1 (en) | 2001-11-01 |
EP1276486B2 (de) | 2014-03-05 |
EP1276486A2 (de) | 2003-01-22 |
EP1276486B8 (de) | 2011-01-19 |
US9814580B2 (en) | 2017-11-14 |
ES2353061T3 (es) | 2011-02-25 |
US20130131804A1 (en) | 2013-05-23 |
WO2001080865A2 (en) | 2001-11-01 |
PT1276486E (pt) | 2011-02-07 |
DE60143517D1 (de) | 2011-01-05 |
JP5090604B2 (ja) | 2012-12-05 |
AU2001257236B2 (en) | 2006-03-09 |
US20090041730A1 (en) | 2009-02-12 |
WO2001080865A3 (en) | 2002-04-11 |
JP2004507454A (ja) | 2004-03-11 |
JP5792686B2 (ja) | 2015-10-14 |
US20120148548A1 (en) | 2012-06-14 |
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