ATE474575T1 - Pyridinverbindungen, ihre verfahren zur herstellung und anwendung - Google Patents

Pyridinverbindungen, ihre verfahren zur herstellung und anwendung

Info

Publication number
ATE474575T1
ATE474575T1 AT00904436T AT00904436T ATE474575T1 AT E474575 T1 ATE474575 T1 AT E474575T1 AT 00904436 T AT00904436 T AT 00904436T AT 00904436 T AT00904436 T AT 00904436T AT E474575 T1 ATE474575 T1 AT E474575T1
Authority
AT
Austria
Prior art keywords
pyridine compounds
production
compounds
useful
pyridine
Prior art date
Application number
AT00904436T
Other languages
English (en)
Inventor
Robert Struck
Herbert Blatter
Anita Tiwari
Original Assignee
Southern Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Res Inst filed Critical Southern Res Inst
Application granted granted Critical
Publication of ATE474575T1 publication Critical patent/ATE474575T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT00904436T 1999-01-21 2000-01-21 Pyridinverbindungen, ihre verfahren zur herstellung und anwendung ATE474575T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11667699P 1999-01-21 1999-01-21
PCT/US2000/001337 WO2000043009A1 (en) 1999-01-21 2000-01-21 Pyridine compounds, use and preparation thereof

Publications (1)

Publication Number Publication Date
ATE474575T1 true ATE474575T1 (de) 2010-08-15

Family

ID=22368577

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00904436T ATE474575T1 (de) 1999-01-21 2000-01-21 Pyridinverbindungen, ihre verfahren zur herstellung und anwendung

Country Status (8)

Country Link
EP (1) EP1143970B1 (de)
JP (1) JP4709386B2 (de)
AT (1) ATE474575T1 (de)
AU (1) AU2619700A (de)
DE (1) DE60044708D1 (de)
ES (1) ES2348972T3 (de)
PT (1) PT1143970E (de)
WO (1) WO2000043009A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000043010A1 (en) * 1999-01-21 2000-07-27 Southern Research Institute Acyl derivatives of 4-demethylpenclomedine, use thereof and preparation thereof
CA2632618C (en) 2005-12-13 2014-04-22 Dekk-Tec, Inc. Demethylpenclomedine analogs and their use as anticancer agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3244722A (en) * 1964-01-28 1966-04-05 Dow Chemical Co Certain ethers of (trichloromethyl) pyridine compounds
US4717726A (en) * 1986-09-10 1988-01-05 The Dow Chemical Company 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)pyridine having anti-tumor activity
AU3294097A (en) * 1996-06-03 1998-01-05 Johns Hopkins University School Of Medicine, The Pyridine derivative, composition and method for treating cancer
WO2000043010A1 (en) * 1999-01-21 2000-07-27 Southern Research Institute Acyl derivatives of 4-demethylpenclomedine, use thereof and preparation thereof

Also Published As

Publication number Publication date
EP1143970B1 (de) 2010-07-21
PT1143970E (pt) 2010-10-27
DE60044708D1 (de) 2010-09-02
ES2348972T3 (es) 2010-12-20
WO2000043009A1 (en) 2000-07-27
AU2619700A (en) 2000-08-07
EP1143970A1 (de) 2001-10-17
JP2002535275A (ja) 2002-10-22
JP4709386B2 (ja) 2011-06-22
EP1143970A4 (de) 2005-07-27

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