ATE460667T1 - Mikroarray-vorrichtungen mit steuerbarem reaktionsvolumen - Google Patents

Mikroarray-vorrichtungen mit steuerbarem reaktionsvolumen

Info

Publication number: ATE460667T1
Authority: AT; Austria
Prior art keywords: microarray; reaction volume; controllable; controllable reaction; microarray devices
Prior art date: 2003-02-20

Application number

AT03714627T

Other languages

English (en)

Inventor

Wanli Xing

Feijun Xian

Xianhua Wang

Jing Cheng

Original Assignee

Capitalbio Corp

Univ Tsinghua

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-02-20

Filing date

2003-03-28

Publication date

2010-03-15

2003-03-28 Application filed by Capitalbio Corp, Univ Tsinghua filed Critical Capitalbio Corp

2010-03-15 Application granted granted Critical

2010-03-15 Publication of ATE460667T1 publication Critical patent/ATE460667T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00504—Pins
- B01J2219/00509—Microcolumns
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00542—Alphanumeric characters
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
- B01J2219/00574—Chemical means radioactive
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
- B01J2219/00576—Chemical means fluorophore
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/0061—The surface being organic
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00657—One-dimensional arrays
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
- B01J2219/00662—Two-dimensional arrays within two-dimensional arrays
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00731—Saccharides
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0822—Slides
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/12—Libraries containing saccharides or polysaccharides, or derivatives thereof

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Analytical Chemistry (AREA)
Hematology (AREA)
Clinical Laboratory Science (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Physical Or Chemical Processes And Apparatus (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT03714627T 2003-02-20 2003-03-28 Mikroarray-vorrichtungen mit steuerbarem reaktionsvolumen ATE460667T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CN03104663.0A CN1217003C (zh)	2003-02-20	2003-02-20	一种微阵列反应装置及其应用
PCT/CN2003/000228 WO2004074835A1 (en)	2003-02-20	2003-03-28	Microarray devices having controllable reaction volume

Publications (1)

Publication Number	Publication Date
ATE460667T1 true ATE460667T1 (de)	2010-03-15

Family

ID=32874032

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03714627T ATE460667T1 (de)	2003-02-20	2003-03-28	Mikroarray-vorrichtungen mit steuerbarem reaktionsvolumen

Country Status (9)

Country	Link
US (1)	US7767438B2 (de)
EP (1)	EP1595144B1 (de)
JP (1)	JP4230460B2 (de)
CN (1)	CN1217003C (de)
AT (1)	ATE460667T1 (de)
AU (1)	AU2003218868A1 (de)
CA (1)	CA2513591A1 (de)
DE (1)	DE60331686D1 (de)
WO (1)	WO2004074835A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1289904C (zh) *	2003-08-01	2006-12-13	博奥生物有限公司	一种微阵列反应装置及其应用
CN100425990C (zh) *	2005-10-17	2008-10-15	中国人民解放军第三军医大学第一附属医院	血液检测微阵列制备方法
KR20090007173A (ko) *	2007-07-13	2009-01-16	삼성전자주식회사	웨이퍼 레벨 패키지, 바이오칩 키트 및 이들의 패키징 방법
US8680025B2 (en) *	2008-05-09	2014-03-25	Akonni Biosystems, Inc.	Microarray system
US20100056382A1 (en) *	2008-05-30	2010-03-04	Sussman Michael R	Dna millichip
CA2768617C (en) *	2009-07-24	2018-03-27	Akonni Biosystems	Flow cell device
KR101050790B1 (ko) *	2010-01-05	2011-07-20	한국과학기술연구원	살아있는 세포 활성 분석 방법
CN102243228A (zh) *	2010-05-13	2011-11-16	南京神州英诺华医疗科技有限公司	一种新型的免疫学检测方法
CN202942869U (zh)	2012-11-07	2013-05-22	博奥生物有限公司	一种微阵列反应装置
CN108212226A (zh) *	2016-12-21	2018-06-29	中国科学院化学研究所	制备微点阵芯片预制板的方法及其应用
AU2019261360A1 (en) *	2018-04-23	2020-03-05	Anpac Bio-Medical Science Co., Ltd.	New apparatus and methods for disease detection
CN108414704A (zh) *	2018-05-25	2018-08-17	济南海能仪器股份有限公司	保护壳体及食用油品质测定仪

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1110570C (zh) *	1998-04-03	2003-06-04	东南大学	多次压印定点合成法制备化合物微阵列芯片的方法
US6159727A (en) *	1999-06-04	2000-12-12	Clontech Laboratories, Inc.	Hybridization chamber
US6258593B1 (en) *	1999-06-30	2001-07-10	Agilent Technologies Inc.	Apparatus for conducting chemical or biochemical reactions on a solid surface within an enclosed chamber
IL147227A0 (en) *	1999-07-02	2002-08-14	Clondiag Chip Tech Gmbh	Microchip matrix device for duplicating and characterizing nucleic acids
CN1261669A (zh)	1999-11-19	2000-08-02	中国人民解放军军事医学科学院放射医学研究所	一种蛋白和基因检测板及其制备方法和应用
TW513485B (en) *	2000-07-10	2002-12-11	Ind Tech Res Inst	On-spot hydrophilic enhanced slide and preparation thereof
US7112305B2 (en) *	2001-01-31	2006-09-26	Agilent Technologies, Inc.	Automation-optimized microarray package
US7407746B2 (en) *	2001-02-08	2008-08-05	Ngk Insulators, Ltd.	Biochip and method for producing the same
CN1138145C (zh) *	2001-04-27	2004-02-11	上海晶泰生物技术有限公司	多样品微阵列生物芯片
EP1373467A4 (de) *	2001-03-28	2007-06-06	Genetech Biotechnology Shangai	Vorrichtung und verfahren zum nachweis mehrerer analyte
US6485918B1 (en) *	2001-07-02	2002-11-26	Packard Bioscience Corporation	Method and apparatus for incubation of a liquid reagent and target spots on a microarray substrate
WO2003022421A2 (en) *	2001-09-07	2003-03-20	Corning Incorporated	Microcolumn-platform based array for high-throughput analysis
US20030157523A1 (en) *	2001-11-20	2003-08-21	Genentech, Inc.	Cell and tissue arrays and microarrays and methods of use
US20040126766A1 (en) *	2002-12-26	2004-07-01	Amorese Douglas A.	Breakaway seal for processing a subarray of an array

2003
- 2003-02-20 CN CN03104663.0A patent/CN1217003C/zh not_active Expired - Fee Related
- 2003-03-28 DE DE60331686T patent/DE60331686D1/de not_active Expired - Fee Related
- 2003-03-28 JP JP2004568369A patent/JP4230460B2/ja not_active Expired - Fee Related
- 2003-03-28 CA CA002513591A patent/CA2513591A1/en not_active Abandoned
- 2003-03-28 EP EP03714627A patent/EP1595144B1/de not_active Expired - Lifetime
- 2003-03-28 WO PCT/CN2003/000228 patent/WO2004074835A1/en active Application Filing
- 2003-03-28 AU AU2003218868A patent/AU2003218868A1/en not_active Abandoned
- 2003-03-28 US US10/546,226 patent/US7767438B2/en not_active Expired - Fee Related
- 2003-03-28 AT AT03714627T patent/ATE460667T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE60331686D1 (de)	2010-04-22
WO2004074835A1 (en)	2004-09-02
JP2006514285A (ja)	2006-04-27
JP4230460B2 (ja)	2009-02-25
AU2003218868A1 (en)	2004-09-09
CA2513591A1 (en)	2004-09-02
EP1595144A1 (de)	2005-11-16
EP1595144A4 (de)	2008-04-02
CN1523344A (zh)	2004-08-25
AU2003218868A8 (en)	2004-09-09
US20060141610A1 (en)	2006-06-29
CN1217003C (zh)	2005-08-31
EP1595144B1 (de)	2010-03-10
US7767438B2 (en)	2010-08-03

Legal Events

Date	Code	Title	Description
2010-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ITTO20030095A1 (it)	2003-09-08	Struttura di dispositivo antiurto.
ATE432361T1 (de)	2009-06-15	Vorrichtung mit integrierter mikromatrize
NO20053169D0 (no)	2005-06-28	Fremgangsmate for fremstilling av integrerte biosensorer.
ATE460667T1 (de)	2010-03-15	Mikroarray-vorrichtungen mit steuerbarem reaktionsvolumen
FR2844364B1 (fr)	2004-12-17	Substrat diffusant
ATE550776T1 (de)	2012-04-15	Strukturausbildung
BR0312249B1 (pt)	2012-05-15	substrato transparente.
ATE459623T1 (de)	2010-03-15	Pyridoä2,3-düpyrimidine, die sich als hcv- inhibitoren eignen und verfahren zu deren herstellung
EP1738820A4 (de)	2007-04-04	Stützeinheit für mikrofluidsystem
TW200700813A (en)	2007-01-01	Jig for substrate and method of fabricating the same
DK1962997T3 (da)	2009-08-31	Isoterm kemisk reaktor
ATE405732T1 (de)	2008-09-15	Abgasbehandlungsvorrichtung und herstellungsverfahren dafür
DK1668125T3 (da)	2014-09-08	Modificerede enzymer, fremgangsmåde til fremstilling af modificerede enzymer og anvendelser deraf
ATE425811T1 (de)	2009-04-15	Chemische und biologische detektionsarrays
ITRE20030073A1 (it)	2005-01-19	Antenna planare monostrato.
ITRM20050526A1 (it)	2006-04-26	Complesso a piastra di supporto e contrasto per un complesso a modulo di processore.
DE50311468D1 (de)	2009-06-10	Grundplatte mit Elektronikmodul
NO20052617A (no)	2006-11-13	Klekkesubstratplate,klekkesubstatmatte og metode for fremstilling av klekkesubstratmatte.
WO2010002445A3 (en)	2010-04-22	Micro-posts having improved uniformity and a method of manufacture thereof
DK1680214T3 (da)	2007-10-15	Pseudo-isotermisk analytisk reaktor
ITMO20040210A1 (it)	2004-11-06	Dispositivo di supporto.
ATE442200T1 (de)	2009-09-15	Hydrierungskatalysatoren
EE05205B1 (et)	2009-08-17	Alusplaat
ES1057528Y (es)	2004-12-01	Estructura soporte.
ES1053739Y (es)	2003-08-16	Dispositivo de soporte multiple.