ATE442842T1 - Verwendung von urokinase-inhibitoren zur behandlung und/oder vorbeugung von amyotrophischer lateralsklerose (als) - Google Patents
Verwendung von urokinase-inhibitoren zur behandlung und/oder vorbeugung von amyotrophischer lateralsklerose (als)Info
- Publication number
- ATE442842T1 ATE442842T1 AT06754517T AT06754517T ATE442842T1 AT E442842 T1 ATE442842 T1 AT E442842T1 AT 06754517 T AT06754517 T AT 06754517T AT 06754517 T AT06754517 T AT 06754517T AT E442842 T1 ATE442842 T1 AT E442842T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibitors
- lateral sclerosis
- amyotrophic lateral
- urocinasis
- als
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69343205P | 2005-06-24 | 2005-06-24 | |
PCT/EP2006/006029 WO2006136419A2 (en) | 2005-06-24 | 2006-06-22 | Use of urokinase inhibitors for the treatment and/or prevention of neuropathological diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE442842T1 true ATE442842T1 (de) | 2009-10-15 |
Family
ID=37570795
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06754517T ATE442842T1 (de) | 2005-06-24 | 2006-06-22 | Verwendung von urokinase-inhibitoren zur behandlung und/oder vorbeugung von amyotrophischer lateralsklerose (als) |
Country Status (13)
Country | Link |
---|---|
US (1) | US8093258B2 (de) |
EP (2) | EP1893185B1 (de) |
JP (1) | JP2008543900A (de) |
KR (1) | KR20080027875A (de) |
AT (1) | ATE442842T1 (de) |
AU (1) | AU2006261099A1 (de) |
CA (1) | CA2612262A1 (de) |
DE (1) | DE602006009257D1 (de) |
ES (1) | ES2329286T3 (de) |
HK (1) | HK1109862A1 (de) |
MX (1) | MX2007016439A (de) |
RU (1) | RU2410087C2 (de) |
WO (1) | WO2006136419A2 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3967322A4 (de) * | 2019-05-10 | 2022-06-08 | Talengen International Limited | Verfahren und medizin zur behandlung von amyotropher lateralsklerose |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5340833A (en) | 1992-05-01 | 1994-08-23 | Eisai Co., Ltd. | Urokinase inhibitors |
US5550213A (en) | 1993-12-27 | 1996-08-27 | Rutgers, The State University Of New Jersey | Inhibitors of urokinase plasminogen activator |
US5952307A (en) | 1994-01-21 | 1999-09-14 | Georgia Tech Research Corp. | Basic α-aminoalkylphosphonate derivatives |
CH689611A5 (de) | 1995-03-01 | 1999-07-15 | Pentapharm Ag | Urokinase-Inhibitoren. |
AUPO227896A0 (en) | 1996-09-13 | 1996-10-03 | Fujisawa Pharmaceutical Co., Ltd. | Novel compounds and their preparation |
US6528619B1 (en) | 1997-04-11 | 2003-03-04 | Roche Diagnostics Gmbh | Inhibitors for urokinase receptor |
ZA986594B (en) | 1997-07-25 | 1999-01-27 | Abbott Lab | Urokinase inhibitors |
GB9721964D0 (en) | 1997-10-16 | 1997-12-17 | Pfizer Ltd | Isoquinolines |
EP1054886B1 (de) * | 1998-02-09 | 2002-09-04 | 3-Dimensional Pharmaceuticals, Inc. | Heteroaryl-amidinen,-methylamidinen und -guanidinen als protease inhibitoren, insbesondere als urokinase inhibitoren |
ES2189455T3 (es) | 1998-07-20 | 2003-07-01 | Wilex Ag | Nuevos agentes inhibidores de la urocinasa. |
US6576613B1 (en) | 1998-07-24 | 2003-06-10 | Corvas International, Inc. | Title inhibitors of urokinase |
WO2000005214A2 (en) | 1998-07-24 | 2000-02-03 | Pfizer Inc. | Isoquinolines as urokinase inhibitors |
ATE264678T1 (de) | 1998-07-29 | 2004-05-15 | Taiho Pharmaceutical Co Ltd | Hemmer der angiogenese und der urokinase produktion und seine medizinische anwendung |
WO2000017158A1 (de) | 1998-09-18 | 2000-03-30 | Pentapharm Ag | Urokinase-inhibitoren |
GB9908410D0 (en) | 1999-04-13 | 1999-06-09 | Pfizer Ltd | Pyridines |
DE19940389A1 (de) | 1999-08-25 | 2001-03-01 | Wilex Biotechnology Gmbh | Selektive Inhibitoren des Urokinase-Plasminogen Aktivators |
US20030232789A1 (en) | 1999-12-15 | 2003-12-18 | Allen Darin Arthur | Salicylamides as serine protease and factor xa inhibitors |
US6207701B1 (en) | 2000-01-28 | 2001-03-27 | Abbott Laboratories | Urokinase inhibitors |
DE10013715A1 (de) | 2000-03-20 | 2001-09-27 | Wilex Biotechnology Gmbh | Hochselektive Inhibitoren des Urokinase-Plasminogenaktivators |
DE10029014A1 (de) | 2000-06-15 | 2001-12-20 | Univ Schiller Jena | Urokinase-Hemmstoffe |
IL149042A0 (en) | 2000-08-11 | 2002-11-10 | Corvas Int Inc | Non-covalent inhibitors of urokinase and blood vessel formation |
US6586405B2 (en) | 2000-08-11 | 2003-07-01 | Corvas International, Inc. | Non-covalent inhibitors of urokinase and blood vessel formation |
DE50211672D1 (de) | 2001-03-21 | 2008-03-27 | Wilex Ag | Urokinase-inhibitoren |
WO2003048127A1 (en) | 2001-12-04 | 2003-06-12 | Corvas International, Inc. | Aromatic heterocyclic non-covalent inhibitors of urokinase and blood vessel formation |
DE50209313D1 (de) | 2001-12-12 | 2007-03-08 | Wilex Ag | Selektive arylguanidinpeptide als urokinaseinhibitoren |
JP4898091B2 (ja) | 2002-03-11 | 2012-03-14 | ザ メディシンズ カンパニー (ライプツィヒ) ゲーエムベーハー | ウロキナーゼの阻害剤、それらの製造および使用 |
DE10225876A1 (de) | 2002-06-11 | 2003-12-24 | Wilex Ag | Guanidinophenylalaninverbindungen als Urokinase-Inhibitoren |
US20080213244A1 (en) * | 2003-05-05 | 2008-09-04 | Wolfgang Sohngen | Glutamate Receptor Antagonists as Neuroprotectives |
DE10323898A1 (de) | 2003-05-26 | 2004-12-23 | Wilex Ag | Hydroxyamidin- und Hydroxyguanidin-Verbindungen als Urokinase-Hemmstoffe |
-
2006
- 2006-06-22 WO PCT/EP2006/006029 patent/WO2006136419A2/en active Application Filing
- 2006-06-22 AT AT06754517T patent/ATE442842T1/de active
- 2006-06-22 AU AU2006261099A patent/AU2006261099A1/en not_active Abandoned
- 2006-06-22 DE DE602006009257T patent/DE602006009257D1/de active Active
- 2006-06-22 ES ES06754517T patent/ES2329286T3/es active Active
- 2006-06-22 CA CA002612262A patent/CA2612262A1/en not_active Abandoned
- 2006-06-22 MX MX2007016439A patent/MX2007016439A/es active IP Right Grant
- 2006-06-22 US US11/922,774 patent/US8093258B2/en not_active Expired - Fee Related
- 2006-06-22 KR KR1020087001816A patent/KR20080027875A/ko not_active Application Discontinuation
- 2006-06-22 EP EP06754517A patent/EP1893185B1/de not_active Not-in-force
- 2006-06-22 EP EP09001466A patent/EP2087885A1/de not_active Withdrawn
- 2006-06-22 JP JP2008517418A patent/JP2008543900A/ja active Pending
- 2006-06-22 RU RU2008102730/15A patent/RU2410087C2/ru not_active IP Right Cessation
-
2008
- 2008-04-10 HK HK08104029.9A patent/HK1109862A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2006136419B1 (en) | 2007-05-31 |
WO2006136419A3 (en) | 2007-04-19 |
EP1893185A2 (de) | 2008-03-05 |
CA2612262A1 (en) | 2006-12-28 |
DE602006009257D1 (de) | 2009-10-29 |
RU2410087C2 (ru) | 2011-01-27 |
ES2329286T3 (es) | 2009-11-24 |
HK1109862A1 (en) | 2008-06-27 |
EP2087885A1 (de) | 2009-08-12 |
KR20080027875A (ko) | 2008-03-28 |
RU2008102730A (ru) | 2009-07-27 |
WO2006136419A2 (en) | 2006-12-28 |
JP2008543900A (ja) | 2008-12-04 |
MX2007016439A (es) | 2008-03-04 |
US8093258B2 (en) | 2012-01-10 |
EP1893185B1 (de) | 2009-09-16 |
US20090069251A1 (en) | 2009-03-12 |
AU2006261099A1 (en) | 2006-12-28 |
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Legal Events
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