ATE439601T1 - Funktionelles assay für protein s - Google Patents

Funktionelles assay für protein s

Info

Publication number
ATE439601T1
ATE439601T1 AT01994446T AT01994446T ATE439601T1 AT E439601 T1 ATE439601 T1 AT E439601T1 AT 01994446 T AT01994446 T AT 01994446T AT 01994446 T AT01994446 T AT 01994446T AT E439601 T1 ATE439601 T1 AT E439601T1
Authority
AT
Austria
Prior art keywords
protein
clotting time
assay
purified
functional assay
Prior art date
Application number
AT01994446T
Other languages
English (en)
Inventor
Yong Dai
Ye Biqing
Kui Chen
Pau Bruguera
Shamay Tang
Daniel Lawson
Original Assignee
Instrumentation Lab Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instrumentation Lab Co filed Critical Instrumentation Lab Co
Application granted granted Critical
Publication of ATE439601T1 publication Critical patent/ATE439601T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT01994446T 2000-12-19 2001-12-19 Funktionelles assay für protein s ATE439601T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25670300P 2000-12-19 2000-12-19
PCT/US2001/050338 WO2002052276A2 (en) 2000-12-19 2001-12-19 Protein s functional assay

Publications (1)

Publication Number Publication Date
ATE439601T1 true ATE439601T1 (de) 2009-08-15

Family

ID=22973254

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01994446T ATE439601T1 (de) 2000-12-19 2001-12-19 Funktionelles assay für protein s

Country Status (8)

Country Link
EP (1) EP1344066B1 (de)
JP (1) JP2004528534A (de)
AT (1) ATE439601T1 (de)
AU (1) AU2002246838B2 (de)
CA (1) CA2432118C (de)
DE (1) DE60139572D1 (de)
ES (1) ES2328453T3 (de)
WO (1) WO2002052276A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2922024B1 (fr) * 2007-10-04 2011-03-25 Stago Diagnostica Methode d'ajustement de la calibration de tests diagnostiques
JP2012526272A (ja) * 2009-05-07 2012-10-25 アンセルム(アンスチチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル) 血栓形成傾向の診断方法
JPWO2012124798A1 (ja) * 2011-03-14 2014-07-24 株式会社シノテスト 試料中の総プロテインsの活性測定試薬及び活性測定方法
WO2017139567A1 (en) * 2016-02-12 2017-08-17 Instrumentation Laboratory Company A two component "mix and use" liquid thromboplastin reagent, methods of making, and methods of use thereof
CN106546574A (zh) * 2016-10-28 2017-03-29 山西太钢不锈钢股份有限公司 一种钢中微量氮的光谱分析和校正方法
IL257229B (en) * 2018-01-30 2022-07-01 Reddress Ltd A blood-conducting device for tissue treatment
KR20210028668A (ko) * 2018-07-06 2021-03-12 가부시키가이샤 엘에스아이 메디엔스 리포좀을 함유하는 액상 혈액응고능력 측정시약

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1230744B (it) * 1989-07-07 1991-10-29 Instrumentation Lab Spa Metodo per la determinazione della attivita' funzionale della proteina s nel plasma umano.
DE4006634A1 (de) * 1990-03-03 1991-09-05 Behringwerke Ag Funktioneller test zur bestimmung der protein s-aktivitaet
DE4427785A1 (de) * 1994-08-08 1996-02-15 Behringwerke Ag Verfahren zum Nachweis von Störungen des Protein C/Protein S-Systems
US5780255A (en) * 1995-06-09 1998-07-14 Instrumentation Laboratory, S.P.A. Protein C pathway screening test

Also Published As

Publication number Publication date
CA2432118A1 (en) 2002-07-04
AU2002246838B2 (en) 2006-12-07
ES2328453T3 (es) 2009-11-13
WO2002052276A2 (en) 2002-07-04
JP2004528534A (ja) 2004-09-16
DE60139572D1 (de) 2009-09-24
EP1344066A2 (de) 2003-09-17
EP1344066B1 (de) 2009-08-12
WO2002052276A9 (en) 2003-07-31
CA2432118C (en) 2008-12-09
WO2002052276A3 (en) 2003-04-17

Similar Documents

Publication Publication Date Title
CA2269109C (en) Protease for activating clotting factor vii
ATE278186T1 (de) Elektrochemischer sensor zur bestimmung der blutgerinnung, ein entsprechendes blutgerinnungsmesssystem sowie ein verfahren zur bestimmung der blutgerinnung
US20020019021A1 (en) Method for determining the anticoagulatory potential of a sample
Exner et al. Testing for new oral anticoagulants with LA-resistant Russells viper venom reagents. An in vitro study
ATE185901T1 (de) Quantitativer gerinnungstest für aktivierten faktor vii
DE60139572D1 (de) Funktionelles assay für protein s
NO920125L (no) Fremgangsmaate for aa bestemme den funksjonelle aktivitetentil fritt protein s eller protein c i en plasmaproeve
CA2162531C (en) Method for specifically detecting a coagulation factor v which has an increased stability toward activated protein c in the activated state
Bader et al. Multicentric evaluation of a new PT reagent based on recombinant human tissue factor and synthetic phospholipids
ES2152531T3 (es) Prueba para determinar el riesgo de trombosis.
EP1367135A1 (de) Verbessertes Verfahren zur Beurteilung der Thrombinbildung in Blutplasma
DK1391205T3 (da) Farmaceutisk præparat med RNA som cofaktor ved hæmostase
CA2019872C (en) Method and kit for determining the functional activity of protein s in human plasma
Nomura et al. Frequency of protein S deficiency in general Japanese population
Howes et al. Effects of three novel metalloproteinases from the venom of the West African saw-scaled viper, Echis ocellatus on blood coagulation and platelets
Brien et al. Discrepant results in INR testing
Kraus The anticoagulant potential of the protein C system in hereditary and acquired thrombophilia: pathomechanisms and new tools for assessing its clinical relevance
CA2162432A1 (en) Calibrator for use in test methods for detecting a defective coagulation factor v
Butenas et al. The influence of von Willebrand factor on factor VIII activity measurements
ES2217739T3 (es) Prueba de coagulacion de sangre mejorada.
BR0200269A (pt) Processo de purificação de proteìnas solúveis das cerdas da l. oblìqua com atividade ativadora de protrombina; processo para determinação parcial da sequência de aminoácidos do ativador de protrombina; processo de determinação da atividade ativadora de protrombina da fração ii, sequência n-terminal e sequência de fragmentos internos da fração ativadora de protrombina, ativador de protrombina e uso do ativador de protrombina
Di Micco et al. Inhibition of antithrombin by protein SV-IV normalizes the coagulation of hemophilic blood
CA2037434A1 (en) Functional assay for determining the protein s activity
WO2000050904A8 (de) Testkit zur analytik der faktor-viii-spaltenden protease
Van den Besselaar et al. Tissue factor-induced coagulation can be inhibited by aprotinin (Trasylol)

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties