ATE43604T1 - Pharmazeutisch aktives salzderivat von 3-hydroxy- 5-(hydroxymethyl)-2methylisonicotinaldehydphosphat. - Google Patents

Pharmazeutisch aktives salzderivat von 3-hydroxy- 5-(hydroxymethyl)-2methylisonicotinaldehydphosphat.

Info

Publication number: ATE43604T1
Authority: AT; Austria
Prior art keywords: salt derivative; hydroxymethyl; hydroxy; active salt; pharmaceutically active
Prior art date: 1984-10-26

Application number

AT85112179T

Other languages

English (en)

Inventor

Giorgio Zagnoli

Ubaldo Conte

Paolo Colombo

Original Assignee

Lisapharma Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-26

Filing date

1985-09-25

Publication date

1989-06-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11206268&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE43604(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1985-09-25 Application filed by Lisapharma Spa filed Critical Lisapharma Spa

1989-06-15 Application granted granted Critical

1989-06-15 Publication of ATE43604T1 publication Critical patent/ATE43604T1/de

Links

150000003839 salts Chemical class 0.000 title abstract 4
ZQUJIOBCBGSBKS-UHFFFAOYSA-N 1-pyrrolidin-1-yl-4-(2,4,6-trimethoxyphenyl)butan-2-one Chemical compound COC1=CC(OC)=CC(OC)=C1CCC(=O)CN1CCCC1 ZQUJIOBCBGSBKS-UHFFFAOYSA-N 0.000 abstract 1
OWYLAEYXIQKAOL-UHFFFAOYSA-N 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone Chemical compound COC1=CC(OC)=CC(OC)=C1C(=O)CCCN1CCCC1 OWYLAEYXIQKAOL-UHFFFAOYSA-N 0.000 abstract 1
229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
239000007795 chemical reaction product Substances 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
NBIIXXVUZAFLBC-UHFFFAOYSA-N phosphoric acid Substances OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 1
NGVDGCNFYWLIFO-UHFFFAOYSA-N pyridoxal 5'-phosphate Chemical compound CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O NGVDGCNFYWLIFO-UHFFFAOYSA-N 0.000 abstract 1
208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
230000000304 vasodilatating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT85112179T 1984-10-26 1985-09-25 Pharmazeutisch aktives salzderivat von 3-hydroxy- 5-(hydroxymethyl)-2methylisonicotinaldehydphosphat. ATE43604T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT23344/84A IT1177061B (it)	1984-10-26	1984-10-26	Derivato salino farmacologicamente attivo del 3-idrossi-5-(idrossimetil)-2-metilisonicotinaldeide fosfato
EP85112179A EP0183002B2 (de)	1984-10-26	1985-09-25	Pharmazeutisch aktives Salzderivat von 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehydphosphat

Publications (1)

Publication Number	Publication Date
ATE43604T1 true ATE43604T1 (de)	1989-06-15

Family

ID=11206268

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85112179T ATE43604T1 (de)	1984-10-26	1985-09-25	Pharmazeutisch aktives salzderivat von 3-hydroxy- 5-(hydroxymethyl)-2methylisonicotinaldehydphosphat.

Country Status (4)

Country	Link
EP (1)	EP0183002B2 (de)
AT (1)	ATE43604T1 (de)
DE (1)	DE3570674D1 (de)
IT (1)	IT1177061B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1241515B (it) *	1990-07-30	1994-01-17	Bromley Limited	Sali dell'acido nicotinico con composti aminobenzilici e loro impiego farmaceutico".

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1236531A (en) *	1969-02-12	1971-06-23	Soc D Etudes Prod Chimique	Adenin derivative
BE759608A (fr) *	1970-01-08	1971-06-01	Soc D Etudes Prod Chimique	Mono pyridoxal phosphate de papaverine, son procede de preparation ainsi que son utilisation therapeutique
FR2134218A1 (en) *	1971-04-27	1972-12-08	Penciolelli Madeleine	Phloroglucinol aminoketones - vasodilators and antispasmodics
BE863754A (fr) *	1978-02-08	1978-05-29	Dechamps Pierre	Nouveaux derives de la vincamine utilisables comme regulateurs de la circulation cerebrale

1984
- 1984-10-26 IT IT23344/84A patent/IT1177061B/it active
1985
- 1985-09-25 EP EP85112179A patent/EP0183002B2/de not_active Expired - Lifetime
- 1985-09-25 AT AT85112179T patent/ATE43604T1/de not_active IP Right Cessation
- 1985-09-25 DE DE8585112179T patent/DE3570674D1/de not_active Expired

Also Published As

Publication number	Publication date
EP0183002B2 (de)	1994-11-30
DE3570674D1 (en)	1989-07-06
IT8423344A0 (it)	1984-10-26
EP0183002A1 (de)	1986-06-04
EP0183002B1 (de)	1989-05-31
IT1177061B (it)	1987-08-26

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Legal Events

Date	Code	Title
1989-11-15	UEP	Publication of translation of european patent specification
1995-07-15	UEP	Publication of translation of european patent specification
2001-06-15	REN	Ceased due to non-payment of the annual fee