ATE431333T1 - Amino-propanolderivate - Google Patents
Amino-propanolderivateInfo
- Publication number
- ATE431333T1 ATE431333T1 AT05752742T AT05752742T ATE431333T1 AT E431333 T1 ATE431333 T1 AT E431333T1 AT 05752742 T AT05752742 T AT 05752742T AT 05752742 T AT05752742 T AT 05752742T AT E431333 T1 ATE431333 T1 AT E431333T1
- Authority
- AT
- Austria
- Prior art keywords
- amino propane
- propane derivatives
- derivatives
- amino
- transplantation
- Prior art date
Links
- WGYKZJWCGVVSQN-UHFFFAOYSA-N propylamine Chemical class CCCN WGYKZJWCGVVSQN-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/094—Esters of phosphoric acids with arylalkanols
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0411929.3A GB0411929D0 (en) | 2004-05-27 | 2004-05-27 | Organic compounds |
| PCT/EP2005/005685 WO2005118523A1 (en) | 2004-05-27 | 2005-05-25 | Amino-propanol derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE431333T1 true ATE431333T1 (de) | 2009-05-15 |
Family
ID=32671206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05752742T ATE431333T1 (de) | 2004-05-27 | 2005-05-25 | Amino-propanolderivate |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7928093B2 (de) |
| EP (1) | EP1753712B1 (de) |
| JP (1) | JP4490482B2 (de) |
| KR (1) | KR100837897B1 (de) |
| CN (1) | CN100575335C (de) |
| AT (1) | ATE431333T1 (de) |
| AU (1) | AU2005250112B2 (de) |
| BR (1) | BRPI0511610A (de) |
| CA (1) | CA2562332A1 (de) |
| DE (1) | DE602005014473D1 (de) |
| ES (1) | ES2327250T3 (de) |
| GB (1) | GB0411929D0 (de) |
| MX (1) | MXPA06013624A (de) |
| PL (1) | PL1753712T3 (de) |
| PT (1) | PT1753712E (de) |
| RU (1) | RU2006146215A (de) |
| WO (1) | WO2005118523A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1622866B1 (de) * | 2003-04-30 | 2012-07-25 | Novartis AG | Aminopropanol-derivate als modulatoren des sphingosin-1-phosphat-rezeptors |
| WO2005041899A2 (en) | 2003-11-03 | 2005-05-12 | University Of Virginia Patent Foundation | Orally available sphingosine 1-phosphate receptor agonists and antagonists |
| WO2006009092A1 (ja) * | 2004-07-16 | 2006-01-26 | Kyorin Pharmaceutical Co., Ltd. | 効果的な医薬の使用法及び副作用発現の防御に関する方法 |
| CA2576388A1 (en) | 2004-08-13 | 2006-02-23 | Praecis Pharmaceuticals, Inc. | Methods and compositions for modulating sphingosine-1-phosphate (s1p) receptor activity |
| EP1806338B1 (de) * | 2004-10-12 | 2016-01-20 | Kyorin Pharmaceutical Co., Ltd. | Verfahren zur herstellung von 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorphenyl[ethyl]-1,3-propandiolhydrochlorid und hydraten davon, und zwischenprodukte in deren herstellung |
| EP1827606A2 (de) | 2004-12-06 | 2007-09-05 | University Of Virginia Patent Foundation | Arylamid-sphingosin-1-phosphat-analoga |
| CN101277687B (zh) * | 2005-10-07 | 2012-07-18 | 杏林制药株式会社 | 以2-氨基-1,3-丙二醇衍生物作为有效成分的肝脏疾病治疗剂及肝脏疾病治疗方法 |
| MX2008009579A (es) | 2006-01-27 | 2008-09-25 | Univ Virginia | Metodo para el tratamiento de dolor neuropatico. |
| TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
| CA2641718A1 (en) * | 2006-02-09 | 2007-08-16 | University Of Virginia Patent Foundation | Bicyclic sphingosine 1-phosphate analogs |
| MX2009001457A (es) * | 2006-08-08 | 2009-02-19 | Kyorin Seiyaku Kk | Derivados de aminoalcohol e inmunosupresores que contienen lo mismo como ingrediente activo. |
| SG174028A1 (en) | 2006-08-08 | 2011-09-29 | Kyorin Seiyaku Kk | Aminophosphoric acid ester derivative and s1p receptor modulator containing the same as active ingredient |
| CA2669102A1 (en) | 2006-11-21 | 2008-05-29 | University Of Virginia Patent Foundation | Tetralin analogs having sphingosine 1-phosphate agonist activity |
| JP2010510250A (ja) | 2006-11-21 | 2010-04-02 | ユニバーシティ オブ バージニア パテント ファンデーション | スフィンゴシン＝１−燐酸受容体アゴニスト活性を有するヒドリンダンアナログ |
| JP2010510251A (ja) | 2006-11-21 | 2010-04-02 | ユニバーシティ オブ バージニア パテント ファンデーション | スフィンゴシン＝１−燐酸受容体活性を有するベンゾシクロヘプチルアナログ |
| WO2008124210A1 (en) * | 2007-02-14 | 2008-10-16 | Emory University | Methods and compositions for treating or preventing infection using leukocyte sequestration agents |
| TW200946105A (en) | 2008-02-07 | 2009-11-16 | Kyorin Seiyaku Kk | Therapeutic agent or preventive agent for inflammatory bowel disease containing amino alcohol derivative as active ingredient |
| AR074062A1 (es) * | 2008-10-31 | 2010-12-22 | Lexicon Pharmaceuticals Inc | Agonistas del receptor s1p para el tratamiento de la malaria cerebral y forma farmaceutica |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5948820A (en) * | 1994-08-22 | 1999-09-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzene compound and pharmaceutical use thereof |
| WO1996006068A1 (fr) | 1994-08-22 | 1996-02-29 | Yoshitomi Pharmaceutical Industries, Ltd. | Compose benzenique et son utilisation medicale |
| JP4045364B2 (ja) * | 1997-04-04 | 2008-02-13 | 田辺三菱製薬株式会社 | ２−アミノプロパン−１，３−ジオール化合物、その医薬としての用途およびその合成中間体 |
| PL367348A1 (en) | 2001-03-26 | 2005-02-21 | Novartis Ag | 2-amino-propanol derivatives |
| EP1539674A1 (de) * | 2002-09-13 | 2005-06-15 | Novartis AG | Aminopropanol-derivate |
| EP1622866B1 (de) * | 2003-04-30 | 2012-07-25 | Novartis AG | Aminopropanol-derivate als modulatoren des sphingosin-1-phosphat-rezeptors |
-
2004
- 2004-05-27 GB GBGB0411929.3A patent/GB0411929D0/en not_active Ceased
-
2005
- 2005-05-25 US US11/568,645 patent/US7928093B2/en not_active Expired - Fee Related
- 2005-05-25 AU AU2005250112A patent/AU2005250112B2/en not_active Ceased
- 2005-05-25 ES ES05752742T patent/ES2327250T3/es active Active
- 2005-05-25 EP EP05752742A patent/EP1753712B1/de not_active Not-in-force
- 2005-05-25 WO PCT/EP2005/005685 patent/WO2005118523A1/en active Application Filing
- 2005-05-25 KR KR1020067024709A patent/KR100837897B1/ko not_active IP Right Cessation
- 2005-05-25 RU RU2006146215/04A patent/RU2006146215A/ru not_active Application Discontinuation
- 2005-05-25 JP JP2007513805A patent/JP4490482B2/ja not_active Expired - Fee Related
- 2005-05-25 PT PT05752742T patent/PT1753712E/pt unknown
- 2005-05-25 CA CA002562332A patent/CA2562332A1/en not_active Abandoned
- 2005-05-25 PL PL05752742T patent/PL1753712T3/pl unknown
- 2005-05-25 AT AT05752742T patent/ATE431333T1/de active
- 2005-05-25 BR BRPI0511610-4A patent/BRPI0511610A/pt not_active IP Right Cessation
- 2005-05-25 CN CN200580012823A patent/CN100575335C/zh not_active Expired - Fee Related
- 2005-05-25 MX MXPA06013624A patent/MXPA06013624A/es active IP Right Grant
- 2005-05-25 DE DE602005014473T patent/DE602005014473D1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| PL1753712T3 (pl) | 2009-10-30 |
| JP2008500302A (ja) | 2008-01-10 |
| MXPA06013624A (es) | 2007-02-28 |
| RU2006146215A (ru) | 2008-07-10 |
| BRPI0511610A (pt) | 2008-01-02 |
| AU2005250112A1 (en) | 2005-12-15 |
| EP1753712B1 (de) | 2009-05-13 |
| JP4490482B2 (ja) | 2010-06-23 |
| KR20070015439A (ko) | 2007-02-02 |
| US20070225260A1 (en) | 2007-09-27 |
| AU2005250112B2 (en) | 2009-01-08 |
| PT1753712E (pt) | 2009-08-06 |
| US7928093B2 (en) | 2011-04-19 |
| EP1753712A1 (de) | 2007-02-21 |
| CA2562332A1 (en) | 2005-12-15 |
| GB0411929D0 (en) | 2004-06-30 |
| DE602005014473D1 (en) | 2009-06-25 |
| CN1946679A (zh) | 2007-04-11 |
| CN100575335C (zh) | 2009-12-30 |
| KR100837897B1 (ko) | 2008-06-13 |
| WO2005118523A1 (en) | 2005-12-15 |
| ES2327250T3 (es) | 2009-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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