ATE429440T1 - Formen prostataspezifischer antigene und verfahren zu deren nachweis - Google Patents

Formen prostataspezifischer antigene und verfahren zu deren nachweis

Info

Publication number
ATE429440T1
ATE429440T1 AT02750561T AT02750561T ATE429440T1 AT E429440 T1 ATE429440 T1 AT E429440T1 AT 02750561 T AT02750561 T AT 02750561T AT 02750561 T AT02750561 T AT 02750561T AT E429440 T1 ATE429440 T1 AT E429440T1
Authority
AT
Austria
Prior art keywords
prostate
forms
detection
specific antigens
ppsa
Prior art date
Application number
AT02750561T
Other languages
English (en)
Inventor
Stephen Mikolajczyk
Mohammad Saedi
Harry Rittenhouse
Abhay Kumar
Robert Wolfert
Original Assignee
Hybritech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybritech Inc filed Critical Hybritech Inc
Application granted granted Critical
Publication of ATE429440T1 publication Critical patent/ATE429440T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21077—Semenogelase (3.4.21.77), i.e. prostate specific antigen or PSA or kallikrein 3
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT02750561T 2001-02-23 2002-02-22 Formen prostataspezifischer antigene und verfahren zu deren nachweis ATE429440T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/792,692 US7288636B2 (en) 1997-04-30 2001-02-23 Forms of prostate specific antigens and methods for their detection
PCT/US2002/005424 WO2002072752A2 (en) 2001-02-23 2002-02-22 Forms of prostate specific antigens and methods for their detection

Publications (1)

Publication Number Publication Date
ATE429440T1 true ATE429440T1 (de) 2009-05-15

Family

ID=25157751

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02750561T ATE429440T1 (de) 2001-02-23 2002-02-22 Formen prostataspezifischer antigene und verfahren zu deren nachweis

Country Status (7)

Country Link
US (1) US7288636B2 (de)
EP (1) EP1392719B1 (de)
AT (1) ATE429440T1 (de)
AU (1) AU2002306568A1 (de)
DE (1) DE60232069D1 (de)
ES (1) ES2324601T3 (de)
WO (1) WO2002072752A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7659073B2 (en) 1997-04-30 2010-02-09 Hybritech Incorporated Forms of prostate specific antigens and methods for their detection
US20090087860A1 (en) * 2007-08-24 2009-04-02 Todd John A Highly sensitive system and methods for analysis of prostate specific antigen (psa)
WO2012006634A2 (en) * 2010-07-09 2012-01-12 The Board Of Trustees Of The University Of Illiniois Prostate specific antigen (psa) peptide therapy
US8557777B2 (en) 2010-07-09 2013-10-15 The Board Of Trustees Of The University Of Illinois Methods for treating cancer using prostate specific antigen and tumor endothelial marker peptides
EP2619588B1 (de) * 2010-09-23 2019-08-07 Biocept, Inc. Verfahren und reagenzien zur verstärkung von signalen
KR20200075023A (ko) 2012-05-04 2020-06-25 화이자 인코포레이티드 전립선 관련된 항원 및 백신 기재 면역치료 요법
CN105929151A (zh) * 2016-06-30 2016-09-07 深圳市亚辉龙生物科技股份有限公司 ***特异性抗原同源异构体化学发光免疫检测试剂盒及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9002480D0 (sv) * 1990-07-23 1990-07-23 Hans Lilja Assay of free and complexed prostate-specific antigen
JPH08502889A (ja) 1992-10-29 1996-04-02 トーマス・ジェファーソン・ユニバーシティ 前立腺癌の微小転移を検出する方法
US6103237A (en) 1993-07-22 2000-08-15 Hybritech Incorporated Stable variant hK2 polypeptide
US5599677A (en) * 1993-12-29 1997-02-04 Abbott Laboratories Immunoassays for prostate specific antigen
EP0725139A3 (de) 1995-02-03 1997-11-26 Bayer Corporation Rekombinantes prostat-spezifisches Antigen und seiner Verwendung als Immunoassay-Kalibrator
ATE404676T1 (de) 1997-04-30 2008-08-15 Hybritech Inc Prostat-spezifisches-antigenformen und verfahren zu ihrer bestimmung
US7674275B2 (en) 2006-10-05 2010-03-09 Ethicon Endo-Surgery, Inc. Suture anchor

Also Published As

Publication number Publication date
EP1392719A4 (de) 2005-10-19
ES2324601T3 (es) 2009-08-11
DE60232069D1 (de) 2009-06-04
AU2002306568A1 (en) 2002-09-24
EP1392719A2 (de) 2004-03-03
US7288636B2 (en) 2007-10-30
EP1392719B1 (de) 2009-04-22
WO2002072752A3 (en) 2003-02-27
WO2002072752A2 (en) 2002-09-19
US20020058291A1 (en) 2002-05-16

Similar Documents

Publication Publication Date Title
HK1077602A1 (en) Use of nucleic acids in preparation of a diagnostic agent for evaluating a disease condition in a patient
WO2005010213A3 (en) Markers for detection of gastric cancer
HUP9701717A2 (hu) Eljárás cPSA-meghatározására
PT1157041E (pt) Anticorpos para terapia e diagnostico de cancro
WO2002031507A3 (en) Non-invasive enzyme screen for tissue remodelling-associated conditions
WO2006039405A3 (en) Drug screening and molecular diagnostic test for early detection of colorectal cancer: reagents, methods and kits thereof
AU5502101A (en) Cancer diagnosis method
BRPI0411200A (pt) método de tratamento de cáncer, métodos de tratamento de paciente humano, artigo industrializado e kit de tratamento de cáncer
EP1855719A4 (de) Neutralisierende monoklonale antikörper gegen coronaviren in zusammenhang mit schwerem akutem atemwegssyndrom
SI1535068T1 (sl) Naprave in postopki za odkrivanje amnijske tekočine v vaginalnih izločkih
DE60129151D1 (de) Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6)
WO2011082345A3 (en) Compositions and methods for cancer management using antibodies binding to nucleotide salvage pathway enzymes and complexes thereof
WO2005040421A3 (en) Prognostic and diagnostic markers for cell proliferative disorders of the breast tissues
ATE429440T1 (de) Formen prostataspezifischer antigene und verfahren zu deren nachweis
AU2002315411A1 (en) Detection and treatment of prostate cancer
ATE404676T1 (de) Prostat-spezifisches-antigenformen und verfahren zu ihrer bestimmung
WO2005069935A3 (en) METHODS FOR MEASURING TRANSFORMING GROWTH FACTOR BETA (TGF-β) RECEPTOR SIGNALING ACTIVITY AND USES THEREOF
ATE445839T1 (de) Latentes tuberkulose-diagnostisches antigen und verwendungsmethode
CA2366514A1 (en) Diagnostic and therapeutic use of antibodies against the urokinase receptor
EP1572225A4 (de) Thrombospondinfragmente und deren verwendung bei klinischen krebs-tests und der erzeugung von antikörpern und sonstigen bindungsmitteln
Gu et al. An evaluation of direct PCR assays for the detection and quantification of Porphyromonas gingivalis
DE60144027D1 (de) 5t4 rna in plasma und serum als marker für neoplastische erkrankungen
NO20054142D0 (no) In vitro diagnostisk test for enterovirale infeksjoner
DE60309879D1 (de) Verfahren zur Diagnose von Krebs
WO2003056341A3 (de) Verfahren zur diagnose von brustkrebserkrankungen, zugehörige peptide und deren verwendungen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties