ATE428688T1 - Funktionelle monomere zur molekularen erkennung und katalyse - Google Patents

Funktionelle monomere zur molekularen erkennung und katalyse

Info

Publication number
ATE428688T1
ATE428688T1 AT01902904T AT01902904T ATE428688T1 AT E428688 T1 ATE428688 T1 AT E428688T1 AT 01902904 T AT01902904 T AT 01902904T AT 01902904 T AT01902904 T AT 01902904T AT E428688 T1 ATE428688 T1 AT E428688T1
Authority
AT
Austria
Prior art keywords
template molecule
catalysis
functional monomers
molecular recognition
monomers
Prior art date
Application number
AT01902904T
Other languages
English (en)
Inventor
Boerje Sellergren
Andrew Hall
Karine Chenon
Rohini Karmalkar
Original Assignee
Mip Technologies Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0000295A external-priority patent/SE0000295D0/xx
Priority claimed from SE0000389A external-priority patent/SE0000389D0/xx
Application filed by Mip Technologies Ab filed Critical Mip Technologies Ab
Application granted granted Critical
Publication of ATE428688T1 publication Critical patent/ATE428688T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/12—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/224—Phosphorus triamides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F267/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated polycarboxylic acids or derivatives thereof as defined in group C08F22/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F273/00—Macromolecular compounds obtained by polymerising monomers on to polymers of sulfur-containing monomers as defined in group C08F28/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F275/00—Macromolecular compounds obtained by polymerising monomers on to polymers of monomers containing phosphorus, selenium, tellurium or a metal as defined in group C08F30/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F289/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds not provided for in groups C08F251/00 - C08F287/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pyridine Compounds (AREA)
AT01902904T 2000-01-28 2001-01-25 Funktionelle monomere zur molekularen erkennung und katalyse ATE428688T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0000295A SE0000295D0 (sv) 2000-01-28 2000-01-28 Functional monomers for molecular recognition and catalysis
SE0000389A SE0000389D0 (sv) 2000-01-28 2000-01-28 Functional monomers for molecular recognition and catalysis
PCT/SE2001/000137 WO2001055095A1 (en) 2000-01-28 2001-01-25 Functional monomers for molecular recognition and catalysis

Publications (1)

Publication Number Publication Date
ATE428688T1 true ATE428688T1 (de) 2009-05-15

Family

ID=26654975

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01902904T ATE428688T1 (de) 2000-01-28 2001-01-25 Funktionelle monomere zur molekularen erkennung und katalyse

Country Status (7)

Country Link
US (3) US6870021B2 (de)
EP (3) EP1927604A1 (de)
JP (1) JP2003520843A (de)
AT (1) ATE428688T1 (de)
AU (1) AU2001230668A1 (de)
DE (1) DE60123575D1 (de)
WO (1) WO2001055095A1 (de)

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EP1927604A1 (de) * 2000-01-28 2008-06-04 MIP Technologies AB Funktionelle Monomere zur molekularen Erkennung und Katalyse
JP3917052B2 (ja) * 2002-10-16 2007-05-23 信和化工株式会社 コポリマー、これを用いた吸着剤又は濃縮媒体、固相マイクロ抽出用注射針
SE0300244D0 (sv) * 2003-01-30 2003-01-30 Mip Technologies Ab Forsknings Molecularly imprinted polymers for extraction of components from foodstuffs
US9035025B2 (en) * 2004-01-30 2015-05-19 Mip Technologies Ab Molecularly imprinted surfaces using surface-bound peptides
DE102004049805A1 (de) * 2004-10-12 2006-04-13 Universität Dortmund Verfahren zur Herstellung von molekulargeprägten Polymeren zur Erkennung von Zielmolekülen
CN100427446C (zh) * 2004-10-20 2008-10-22 天津科技大学 用于富集、分离、纯化香兰素的分子印迹材料
CN100344682C (zh) * 2005-01-05 2007-10-24 中国科学院大连化学物理研究所 一种苯脲类除草剂的分子印迹聚合物的制备方法
CN100374860C (zh) * 2006-02-16 2008-03-12 上海交通大学 氯霉素分子印迹固相萃取小柱的制备方法
JP4802335B2 (ja) * 2007-03-26 2011-10-26 国立大学法人名古屋大学 エステル合成用触媒及びエステルの製造方法
DK2212020T3 (en) * 2007-11-12 2018-10-01 Surecapture Tech Ab EMBROIDERED POLYMERS WITH AFFINITY FOR PHOSHORIORED PEPTIDES AND PROTEINS
EP3708682B1 (de) 2008-02-01 2022-11-23 The General Hospital Corporation Verwendung von mikrovesikeln bei der diagnose und prognose von medizinischen krankheiten und leiden
US11266736B2 (en) 2008-04-17 2022-03-08 Vin De Bona Trading Company Pte Ltd Method of painting micro vesicles
US8835078B2 (en) * 2009-02-11 2014-09-16 Yanxiu Zhou Proton selective membrane for solid polymer fuel cells
SG2014014617A (en) 2009-07-16 2014-05-29 Gen Hospital Corp Nucleic acid analysis
US20120225962A1 (en) * 2009-08-05 2012-09-06 Monash University Molecularly imprinted polymers, methods for their production and uses thereof
WO2011031877A1 (en) 2009-09-09 2011-03-17 The General Hospital Corporation Use of microvesicles in analyzing nucleic acid profiles
EP2475989A4 (de) 2009-09-09 2013-02-27 Gen Hospital Corp Verwendung von mikrovesikeln bei der analyse von kras-mutationen
US20140045915A1 (en) 2010-08-31 2014-02-13 The General Hospital Corporation Cancer-related biological materials in microvesicles
JP6219721B2 (ja) 2010-11-10 2017-10-25 エキソソーム ダイアグノスティックス インコーポレイテッド 核酸含有粒子の単離および該粒子からの核酸の抽出のための方法
CA2835641C (en) 2011-05-11 2019-05-28 Exosome Diagnostics, Inc. Nucleic acid extraction from heterogeneous biological materials
US9192193B2 (en) 2011-05-19 2015-11-24 R.J. Reynolds Tobacco Company Molecularly imprinted polymers for treating tobacco material and filtering smoke from smoking articles
EP3564393A1 (de) 2011-06-21 2019-11-06 Alnylam Pharmaceuticals, Inc. Assays und verfahren zur bestimmung der aktivität eines therapeutikums bei einem patienten
EP2748335B1 (de) 2011-08-22 2018-10-03 Exosome Diagnostics, Inc. Urinbiomarker
WO2013170914A1 (en) * 2012-05-16 2013-11-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. Polymer matrix with target binding site for creatinine and derivatives thereof, its preparation and uses
JP6008177B2 (ja) * 2012-08-15 2016-10-19 株式会社伏見製薬所 分子認識ポリマーの製造方法
WO2014055775A1 (en) 2012-10-03 2014-04-10 Exosome Diagnostics, Inc. Use of microvesicles in diagnosis, prognosis, and treatment of medical diseases and conditions
US20150233800A1 (en) 2012-10-11 2015-08-20 Vin-De-Bona Trading Company Pte Ltd Method of painting microvesicles
US10301681B2 (en) 2013-08-06 2019-05-28 Exosome Diagnostics, Inc. Methods of treating a subject with a high gleason score prostate cancer
WO2015021145A1 (en) * 2013-08-06 2015-02-12 Board Of Regents, The University Of Texas System Molecular imprinted colored silica beads
US10837961B2 (en) 2013-08-06 2020-11-17 Board Of Regents, The University Of Texas System Molecular imprinted colored silica beads
US10703805B2 (en) 2013-10-18 2020-07-07 Board Of Regents, The University Of Texas System Molecular imprinting of West Nile antibodies with physiological pH matching
DE102014101663A1 (de) 2014-02-11 2015-08-13 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Synthetische artifizielle Peptide mit antimikrobieller Wirkung
EP3125907A4 (de) 2014-04-01 2017-11-29 Cornell University Verwendung von doppelsträngiger dna in exosomen: neuartiger biomarker zur krebsdetektion
EP3808756A1 (de) 2014-07-17 2021-04-21 The Trustees of The University of Pennsylvania Verfahren zur verwendung von exosomen zur überwachung des zustands eines transplantierten organs
CN106179261A (zh) * 2016-07-07 2016-12-07 江苏大学 一种金纳米粒子表面荧光分子印迹聚合物的制备方法
GB201621400D0 (en) * 2016-12-15 2017-02-01 Univ Of Reading The Repairable polymer compositions
US11899024B2 (en) 2017-07-12 2024-02-13 Exosome Diagnostics, Inc. Treatment and diagnosis of parkinson's disease using isolated and enriched populations of biofluid-derived extracellular vesicles
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EP1927604A1 (de) * 2000-01-28 2008-06-04 MIP Technologies AB Funktionelle Monomere zur molekularen Erkennung und Katalyse

Also Published As

Publication number Publication date
DE60123575T2 (de) 2007-06-21
US7332553B2 (en) 2008-02-19
US20030166798A1 (en) 2003-09-04
US6870021B2 (en) 2005-03-22
EP1250315B1 (de) 2009-04-15
EP1927604A1 (de) 2008-06-04
US20050159570A1 (en) 2005-07-21
EP1250315A1 (de) 2002-10-23
DE60123575D1 (de) 2009-10-01
EP2065365A3 (de) 2009-06-24
EP2065365A2 (de) 2009-06-03
US7208557B2 (en) 2007-04-24
JP2003520843A (ja) 2003-07-08
AU2001230668A1 (en) 2001-08-07
US20070106041A1 (en) 2007-05-10
WO2001055095A1 (en) 2001-08-02

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