ATE426611T1 - Verfahren zur reinigung eines kalziumionen- bindenden proteins - Google Patents
Verfahren zur reinigung eines kalziumionen- bindenden proteinsInfo
- Publication number
- ATE426611T1 ATE426611T1 AT01951897T AT01951897T ATE426611T1 AT E426611 T1 ATE426611 T1 AT E426611T1 AT 01951897 T AT01951897 T AT 01951897T AT 01951897 T AT01951897 T AT 01951897T AT E426611 T1 ATE426611 T1 AT E426611T1
- Authority
- AT
- Austria
- Prior art keywords
- calcium ion
- binding protein
- purifying
- protein
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6432—Coagulation factor Xa (3.4.21.6)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4721—Lipocortins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4728—Calcium binding proteins, e.g. calmodulin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21006—Coagulation factor Xa (3.4.21.6)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Removal Of Specific Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000220600 | 2000-07-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE426611T1 true ATE426611T1 (de) | 2009-04-15 |
Family
ID=18715177
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01951897T ATE426611T1 (de) | 2000-07-21 | 2001-07-18 | Verfahren zur reinigung eines kalziumionen- bindenden proteins |
Country Status (9)
Country | Link |
---|---|
US (2) | US6869934B2 (de) |
EP (1) | EP1306383B1 (de) |
KR (1) | KR100841599B1 (de) |
CN (1) | CN1250567C (de) |
AT (1) | ATE426611T1 (de) |
AU (1) | AU2001272736A1 (de) |
CA (1) | CA2385371A1 (de) |
DE (1) | DE60138111D1 (de) |
WO (1) | WO2002008249A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103025757A (zh) | 2010-04-29 | 2013-04-03 | 巴克斯特国际有限公司 | 二价阳离子结合蛋白在阴离子交换树脂上的纯化方法 |
CN102382168A (zh) * | 2010-09-03 | 2012-03-21 | 中国科学院过程工程研究所 | 一种高效纯化金属离子结合蛋白的离子交换层析分离纯化方法 |
WO2013053888A1 (en) | 2011-10-14 | 2013-04-18 | Baxter International Inc. | Protein purification by anion exchange chromatography |
JP6236008B2 (ja) | 2011-10-14 | 2017-11-22 | バクスアルタ ゲーエムベーハー | アニオン交換クロマトグラフィーによるタンパク質の精製 |
SI2970376T1 (sl) | 2013-03-15 | 2018-09-28 | Baxalta Incorporated | Metoda čiščenja za vitamin k odvisne proteine z anionsko izmenjevalno kromatografijo |
CN109562352B (zh) * | 2016-08-01 | 2021-12-28 | 株式会社钟化 | 钙蛋白粒子的吸附材料以及吸附除去***及其利用方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1265446A (en) | 1985-09-30 | 1990-02-06 | Masahiro Maki | Anticoagulating substance, process for preparing same and anticoagulant comprising same as an effective component |
JP2660514B2 (ja) | 1987-02-20 | 1997-10-08 | 興和株式会社 | 抗血液凝固作用を有するポリペプチド |
US4981952A (en) | 1988-10-04 | 1991-01-01 | Eli Lilly And Company | Method for the purification of vitamin K-dependent proteins |
DE59002895D1 (de) * | 1989-07-15 | 1993-11-04 | Boehringer Ingelheim Int | Verfahren zur reinigung von annexinen. |
JP2743207B2 (ja) | 1990-01-25 | 1998-04-22 | 財団法人化学及血清療法研究所 | Cpb―iの製造方法並びにこれに用いる組換えプラスミドおよび形質転換酵母 |
DE4406515C1 (de) | 1994-02-28 | 1995-10-19 | Immuno Ag | Verfahren zur Isolierung und Reinigung Vitamin K-abhängiger Proteine |
EP0772778B1 (de) * | 1994-07-23 | 1999-10-27 | Roche Diagnostics GmbH | Verfahren zur bestimmung des präthrombotischen status |
EP0731166A3 (de) | 1995-03-06 | 1997-12-29 | Tonen Corporation | Neue Calcium-bindende Proteine |
US5976832A (en) * | 1995-03-06 | 1999-11-02 | Tonen Corporation | DNA encoding novel calcium-binding proteins |
US5658877A (en) * | 1995-05-18 | 1997-08-19 | Wisconsin Alumni Research Foundation | Method to treat endotoxin effects by administration of 33 kilodalton phospholipid binding protein |
US6645465B2 (en) * | 1999-08-06 | 2003-11-11 | Michigan, University Of The Regents | Annexin proteins and autoantibodies as serum markers for cancer |
-
2001
- 2001-07-18 AT AT01951897T patent/ATE426611T1/de not_active IP Right Cessation
- 2001-07-18 US US10/088,588 patent/US6869934B2/en not_active Expired - Fee Related
- 2001-07-18 DE DE60138111T patent/DE60138111D1/de not_active Expired - Lifetime
- 2001-07-18 EP EP01951897A patent/EP1306383B1/de not_active Expired - Lifetime
- 2001-07-18 AU AU2001272736A patent/AU2001272736A1/en not_active Abandoned
- 2001-07-18 CN CNB01802811XA patent/CN1250567C/zh not_active Expired - Fee Related
- 2001-07-18 CA CA002385371A patent/CA2385371A1/en not_active Abandoned
- 2001-07-18 WO PCT/JP2001/006209 patent/WO2002008249A1/ja active Application Filing
- 2001-07-18 KR KR1020027003471A patent/KR100841599B1/ko not_active IP Right Cessation
-
2004
- 2004-09-21 US US10/944,810 patent/US20050059805A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR100841599B1 (ko) | 2008-06-26 |
CN1250567C (zh) | 2006-04-12 |
WO2002008249A1 (fr) | 2002-01-31 |
KR20020057960A (ko) | 2002-07-12 |
EP1306383A4 (de) | 2005-01-26 |
EP1306383A1 (de) | 2003-05-02 |
DE60138111D1 (de) | 2009-05-07 |
CN1392878A (zh) | 2003-01-22 |
EP1306383B1 (de) | 2009-03-25 |
US6869934B2 (en) | 2005-03-22 |
US20050059805A1 (en) | 2005-03-17 |
US20020169294A1 (en) | 2002-11-14 |
AU2001272736A1 (en) | 2002-02-05 |
CA2385371A1 (en) | 2002-01-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |