ATE426605T1 - Inhibitoren von mitotischem kinesin - Google Patents

Inhibitoren von mitotischem kinesin

Info

Publication number: ATE426605T1
Authority: AT; Austria
Prior art keywords: inhibitors; mitotic kinesin; compounds; ksp kinesin; treating
Prior art date: 2003-06-12

Application number

AT04776354T

Other languages

English (en)

Inventor

Paul Coleman

Lou Anne Neilson

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-12

Filing date

2004-06-08

Publication date

2009-04-15

2004-06-08 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

2009-04-15 Application granted granted Critical

2009-04-15 Publication of ATE426605T1 publication Critical patent/ATE426605T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered

AT04776354T 2003-06-12 2004-06-08 Inhibitoren von mitotischem kinesin ATE426605T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US47797503P	2003-06-12	2003-06-12

Publications (1)

Publication Number	Publication Date
ATE426605T1 true ATE426605T1 (de)	2009-04-15

Family

ID=33539075

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04776354T ATE426605T1 (de)	2003-06-12	2004-06-08	Inhibitoren von mitotischem kinesin

Country Status (9)

Country	Link
US (1)	US7427637B2 (de)
EP (1)	EP1635641B1 (de)
JP (1)	JP2007501863A (de)
CN (1)	CN100403900C (de)
AT (1)	ATE426605T1 (de)
AU (1)	AU2004249138B2 (de)
CA (1)	CA2527533A1 (de)
DE (1)	DE602004020221D1 (de)
WO (1)	WO2004112699A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060234984A1 (en) *	2003-08-15	2006-10-19	Coleman Paul J	Mitotic kinesin inhibitors
CA2702922C (en) *	2007-10-19	2018-01-16	Schering Corporation	Spiro-condensed 1,3,4-thiadiazole derivatives for inhibiting ksp kinesin activity
WO2011064376A1 (en)	2009-11-30	2011-06-03	Novartis Ag	Imidazole derivatives as aldosterone synthase inhibitors
CA2805265A1 (en)	2010-08-02	2012-02-09	Merck Sharp & Dohme Corp.	Rna interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (ctnnb1) gene expression using short interfering nucleic acid (sina)
JO3210B1 (ar) *	2011-10-28	2018-03-08	Merck Sharp & Dohme	مثبط منصهر لبروتين نقل الكوليسترليستير اوكسازوليدينون ثمائي الحلقة
MX363243B (es)	2012-11-28	2019-03-14	Merck Sharp & Dohme	Composiciones para tratar cáncer y usos de dichas composiciones.
CA2990398A1 (en) *	2015-06-23	2016-12-29	Bayer Pharma Aktiengesellschaft	Antibody drug conjugates of kinesin spindel protein (ksp) inhibitors with anti-cd123-antibodies
AU2018252546A1 (en)	2017-04-13	2019-10-10	Sairopa B.V.	Anti-SIRPα antibodies

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW224974B (de) *	1991-07-02	1994-06-11	Hoffmann La Roche
DE10004157A1 (de) *	2000-02-01	2001-08-02	Merckle Gmbh Chem Pharm Fabrik	4-Pyridyl-und 2,4-Pyrimidinyl-substituierte Pyrrolderivate und ihre Anwendung in der Pharmazie
BR0311784A (pt)	2002-06-14	2005-03-08	Merck & Co Inc	Composto, composição farmacêutica, métodos de tratar ou prevenir o câncer, de modular a formação do fuso mitótico e de inibir a cinesina mitótica e processo para fabricar uma composição farmacêutica

2004
- 2004-06-08 CA CA002527533A patent/CA2527533A1/en not_active Abandoned
- 2004-06-08 AT AT04776354T patent/ATE426605T1/de not_active IP Right Cessation
- 2004-06-08 JP JP2006533604A patent/JP2007501863A/ja active Pending
- 2004-06-08 CN CNB2004800164453A patent/CN100403900C/zh not_active Expired - Fee Related
- 2004-06-08 US US10/559,855 patent/US7427637B2/en not_active Expired - Fee Related
- 2004-06-08 EP EP04776354A patent/EP1635641B1/de active Active
- 2004-06-08 WO PCT/US2004/018137 patent/WO2004112699A2/en active Application Filing
- 2004-06-08 AU AU2004249138A patent/AU2004249138B2/en not_active Ceased
- 2004-06-08 DE DE602004020221T patent/DE602004020221D1/de active Active

Also Published As

Publication number	Publication date
CN1805686A (zh)	2006-07-19
CA2527533A1 (en)	2004-12-29
US20060142278A1 (en)	2006-06-29
EP1635641B1 (de)	2009-03-25
WO2004112699A3 (en)	2005-04-14
EP1635641A2 (de)	2006-03-22
AU2004249138B2 (en)	2008-07-17
EP1635641A4 (de)	2006-12-20
US7427637B2 (en)	2008-09-23
DE602004020221D1 (de)	2009-05-07
CN100403900C (zh)	2008-07-23
JP2007501863A (ja)	2007-02-01
AU2004249138A1 (en)	2004-12-29
WO2004112699A2 (en)	2004-12-29

Legal Events

Date	Code	Title	Description
2009-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE446094T1 (de)	2009-11-15	Mitotische kinesin-hemmer
ATE421512T1 (de)	2009-02-15	Inhibitoren von mitotischem kinesin
ATE356804T1 (de)	2007-04-15	Inhibitoren von mitotischem kinesin
DE60222302D1 (de)	2007-10-18	Inhibitoren von mitotischem kinesin
ATE424388T1 (de)	2009-03-15	Mitotische kinesinhemmer
ATE447577T1 (de)	2009-11-15	Mitotische kinesin-hemmer
ATE448207T1 (de)	2009-11-15	Mitotische kinesin-hemmer
WO2004039774A3 (en)	2004-07-01	Mitotic kinesin inhibitors
WO2003099211A3 (en)	2004-02-26	Mitotic kinesin inhibitors
WO2004037171A3 (en)	2004-07-08	Mitotic kinesin inhibitors
WO2005017190A3 (en)	2005-12-15	Mitotic kinesin inhibitors
WO2005018547A3 (en)	2005-09-15	Mitotic kinesin inhibitors
WO2004058148A3 (en)	2004-09-16	Mitotic kinesin inhibitors
WO2004058700A3 (en)	2004-10-14	Mitotic kinesin inhibitors
WO2005065183A3 (en)	2005-09-29	Mitotic kinesin inhibitors
WO2006007496A3 (en)	2006-10-05	Mitotic kinesin inhibitors
NO20070589L (no)	2007-03-22	Mitotiske kinesin-inhibitorer.
ATE426605T1 (de)	2009-04-15	Inhibitoren von mitotischem kinesin
WO2006023440A3 (en)	2007-03-15	Mitotic kinesin inhibitors
WO2005060654A3 (en)	2005-12-08	Mitotic kinesin inhibitors
WO2004087050A3 (en)	2005-03-24	Mitotic kinesin inhibitors