ATE418563T1 - Nik proteine, nukleinsäure sowie verfahren - Google Patents

Nik proteine, nukleinsäure sowie verfahren

Info

Publication number
ATE418563T1
ATE418563T1 AT98934252T AT98934252T ATE418563T1 AT E418563 T1 ATE418563 T1 AT E418563T1 AT 98934252 T AT98934252 T AT 98934252T AT 98934252 T AT98934252 T AT 98934252T AT E418563 T1 ATE418563 T1 AT E418563T1
Authority
AT
Austria
Prior art keywords
nik
methods
disclosed
nucleic acid
nik proteins
Prior art date
Application number
AT98934252T
Other languages
English (en)
Inventor
Mike Rothe
Lin Wu
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE418563T1 publication Critical patent/ATE418563T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT98934252T 1997-07-03 1998-07-02 Nik proteine, nukleinsäure sowie verfahren ATE418563T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/887,518 US5843721A (en) 1997-07-03 1997-07-03 Nucleic acids encoding human NIK protein

Publications (1)

Publication Number Publication Date
ATE418563T1 true ATE418563T1 (de) 2009-01-15

Family

ID=25391324

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98934252T ATE418563T1 (de) 1997-07-03 1998-07-02 Nik proteine, nukleinsäure sowie verfahren

Country Status (9)

Country Link
US (3) US5843721A (de)
EP (1) EP1012174B1 (de)
JP (1) JP2001510348A (de)
AT (1) ATE418563T1 (de)
AU (1) AU724178B2 (de)
CA (1) CA2295999C (de)
DE (1) DE69840387D1 (de)
ES (1) ES2319938T3 (de)
WO (1) WO1999001471A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA71889C2 (uk) * 1996-04-02 2005-01-17 Йєда Рісерч Енд Дівелопмент Ко. Лтд. Модулятори зв'язаного з рецептором tnf фактора (traf), їх одержання та застосування
AU726383B2 (en) * 1996-08-26 2000-11-02 Signal Pharmaceuticals, Inc. Stimulus-inducible I (KAPPA)B kinase (IKK) signalsome
US5851812A (en) * 1997-07-01 1998-12-22 Tularik Inc. IKK-β proteins, nucleic acids and methods
US6235512B1 (en) * 1997-07-01 2001-05-22 Tularik Inc. IKK-α proteins, nucleic acids and methods
US6087169A (en) * 1997-08-04 2000-07-11 Smithkline Beecham Plc HKABY60: polynucleotide encoding a helix-loop-helix ubiquitous kinase family polypeptide
US6242253B1 (en) * 1997-10-09 2001-06-05 Regents Of The University Of California IkB kinase, subunits thereof, and methods of using same
WO1999043704A1 (en) * 1998-02-27 1999-09-02 The Regents Of The University Of California A NOVEL INHIBITOR OF THE INFLAMMATORY RESPONSE INDUCED BY TNFα AND IL-1
US6830884B1 (en) * 1998-12-15 2004-12-14 Molecular Staging Inc. Method of amplification
US6468755B1 (en) 1999-08-10 2002-10-22 Joslin Diabetes Center, Inc. Method for identifying compounds for treatment of insulin resistance
US6630312B2 (en) 1999-08-10 2003-10-07 Joslin Diabetes Center, Inc. Method for identifying compounds for treatment of insulin resistance
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
US6649654B1 (en) * 1999-11-23 2003-11-18 The Regents Of The University Of California Methods for identifying and using IKK inhibitors
WO2001068648A1 (en) * 2000-03-15 2001-09-20 Aventis Pharma Deutschland Gmbh Substituted beta-carbolines with ikb-kinase inhibiting activity
CN100509810C (zh) 2000-03-15 2009-07-08 萨诺费－阿文蒂斯德国有限公司 取代的β-咔啉
EP1209158A1 (de) * 2000-11-18 2002-05-29 Aventis Pharma Deutschland GmbH Substitutierte beta-Carboline
US20030044852A1 (en) * 2000-08-10 2003-03-06 Joslin Diabetes Center, Inc., A Massachusetts Corporation Methods for treatment of insulin resistance
WO2002027321A2 (en) 2000-09-26 2002-04-04 Health Research Incorporated Analysis of hiv-1 coreceptor use in the clinical care of hiv-1-infected patients
CA2427284A1 (en) * 2000-10-26 2002-05-30 Tularik Inc. Antiinflammation agents
US20050227228A1 (en) * 2001-06-05 2005-10-13 Lori Friedman Map3ks as modifiers of the p53 pathway and methods of use
SG2011076551A (en) 2001-06-26 2015-08-28 Amgen Inc Antibodies to opgl
JP4435574B2 (ja) * 2002-04-18 2010-03-17 イエダ リサーチ アンド ディベロップメント カンパニー リミテッド ＩＬ−２レセプターγ鎖の誘導体、その製法および使用
US7459273B2 (en) * 2002-10-04 2008-12-02 Affymetrix, Inc. Methods for genotyping selected polymorphism
CA2511823A1 (en) 2002-12-30 2004-07-22 Amgen Inc. Combination therapy with co-stimulatory factors
IL158287A0 (en) * 2003-10-07 2004-05-12 Yeda Res & Dev Antibodies to nik, their preparation and use
WO2005033145A1 (en) * 2003-10-07 2005-04-14 Yeda Research And Development Co. Ltd. Antibodies to nik, their preparation and use
EP1689786B1 (de) * 2003-11-30 2014-05-14 Yeda Research And Development Co., Ltd. Verfahren und mittel zur immunmodulierung und verfahren zur identifizierung von immunmodulatoren
US7824857B2 (en) * 2003-12-02 2010-11-02 Musc Foundation For Research Development Methods and compositions for diagnosing epithelial cell cancer
US7981616B2 (en) * 2004-02-27 2011-07-19 Musc Foundation For Research Development Enhanced detection of RNA using a panel of truncated gene-specific primers for reverse transcription
EP2468889A3 (de) * 2004-07-09 2012-07-11 University of Pittsburgh of the Commonwealth System of Higher Education Identifizierung von Markern für Lungen- und Brustkrebs
IL166006A0 (en) * 2004-12-27 2006-01-15 Yeda Res & Dev Pharmaceutical compositions for treating diseases associated with nf-kb activity
IL173104A0 (en) * 2006-01-12 2006-06-11 Yeda Res & Dev Siva and ubiquintination

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07502164A (ja) * 1991-09-20 1995-03-09 フレッド ハッチンソン キャンサー リサーチ センター ヒトサイクリンｅ
UA71889C2 (uk) * 1996-04-02 2005-01-17 Йєда Рісерч Енд Дівелопмент Ко. Лтд. Модулятори зв'язаного з рецептором tnf фактора (traf), їх одержання та застосування

Also Published As

Publication number Publication date
ES2319938T3 (es) 2009-05-14
CA2295999A1 (en) 1999-01-14
EP1012174B1 (de) 2008-12-24
EP1012174A1 (de) 2000-06-28
AU724178B2 (en) 2000-09-14
US5843721A (en) 1998-12-01
JP2001510348A (ja) 2001-07-31
US5854003A (en) 1998-12-29
EP1012174A4 (de) 2002-07-03
WO1999001471A1 (en) 1999-01-14
WO1999001471A9 (en) 2008-04-17
CA2295999C (en) 2004-04-27
DE69840387D1 (de) 2009-02-05
AU8382098A (en) 1999-01-25
US5844073A (en) 1998-12-01

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