ATE415966T1 - Substituierte 3-amino-thieno(2,3-b)pyridine-2- amide und herstellungsverfahren sowie deren verwendung - Google Patents

Substituierte 3-amino-thieno(2,3-b)pyridine-2- amide und herstellungsverfahren sowie deren verwendung

Info

Publication number: ATE415966T1
Authority: AT; Austria
Prior art keywords: thieno; amides; pyridine; amino; substituted
Prior art date: 2002-06-06

Application number

AT03736796T

Other languages

German (de)

English (en)

Inventor

Ch L Cywin

Z Chen

Jonathan Emeigh

R W Fleck

M Hao

E Hickey

W Liu

D R Marshall

Tina M Morwick

P Nemoto

R J Sorcek

S Sun

J Wu

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-06-06

Filing date

2003-06-03

Publication date

2008-12-15

2003-06-03 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2008-12-15 Application granted granted Critical

2008-12-15 Publication of ATE415966T1 publication Critical patent/ATE415966T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
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- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/68—Polyesters containing atoms other than carbon, hydrogen and oxygen
- C08G63/695—Polyesters containing atoms other than carbon, hydrogen and oxygen containing silicon
- C08G63/6954—Polyesters containing atoms other than carbon, hydrogen and oxygen containing silicon derived from polxycarboxylic acids and polyhydroxy compounds
- C08G63/6956—Dicarboxylic acids and dihydroxy compounds
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/91—Polymers modified by chemical after-treatment
- C08G63/914—Polymers modified by chemical after-treatment derived from polycarboxylic acids and polyhydroxy compounds
- C08G63/916—Dicarboxylic acids and dihydroxy compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Pulmonology (AREA)
Neurology (AREA)
Polymers & Plastics (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Dermatology (AREA)
Toxicology (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Oncology (AREA)
Transplantation (AREA)
Vascular Medicine (AREA)
Obesity (AREA)
Endocrinology (AREA)

AT03736796T 2002-06-06 2003-06-03 Substituierte 3-amino-thieno(2,3-b)pyridine-2- amide und herstellungsverfahren sowie deren verwendung ATE415966T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US38631202P	2002-06-06	2002-06-06
US45786703P	2003-03-26	2003-03-26

Publications (1)

Publication Number	Publication Date
ATE415966T1 true ATE415966T1 (de)	2008-12-15

Family

ID=29739900

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03736796T ATE415966T1 (de)	2002-06-06	2003-06-03	Substituierte 3-amino-thieno(2,3-b)pyridine-2- amide und herstellungsverfahren sowie deren verwendung

Country Status (27)

Country	Link
US (2)	US6964956B2 (no)
EP (2)	EP1513516B1 (no)
JP (2)	JP4364120B2 (no)
KR (1)	KR20050005548A (no)
CN (1)	CN100386329C (no)
AR (1)	AR040250A1 (no)
AT (1)	ATE415966T1 (no)
AU (1)	AU2003237330A1 (no)
BR (1)	BR0311605A (no)
CA (1)	CA2483890C (no)
DE (1)	DE60325051D1 (no)
DK (1)	DK1513516T3 (no)
EA (1)	EA008706B1 (no)
ES (1)	ES2318141T3 (no)
HK (1)	HK1080737A1 (no)
HR (1)	HRP20041154A2 (no)
IL (1)	IL164597A0 (no)
ME (2)	MEP53508A (no)
MX (1)	MXPA04011246A (no)
NO (1)	NO20044599L (no)
NZ (1)	NZ537394A (no)
PE (1)	PE20040539A1 (no)
PL (1)	PL373424A1 (no)
RS (1)	RS105204A (no)
TW (1)	TWI296927B (no)
UY (1)	UY27834A1 (no)
WO (1)	WO2003103661A1 (no)

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EP1681292A1 (de) *	2005-01-12	2006-07-19	IBFB Pharma GmbH	3-Amino-6-aryl(bzw.6-heteroaryl)-thieno¬2,3-b\|pyridin-2-carbonsäureamide, diese enthaltende pharmazeutische Zubereitungen und ihre Verwendung als Inhibitoren der TNFalpha-Freisetzung
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CN1884262B (zh) *	2005-06-24	2014-06-25	中国人民解放军军事医学科学院毒物药物研究所	4-氨基哌啶类化合物及其医药用途
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US20080032409A1 (en) *	2006-08-07	2008-02-07	California Institute Of Technology	Fluorescent biomolecule labeling reagents
WO2008020622A1 (fr) *	2006-08-17	2008-02-21	Kyorin Pharmaceutical Co., Ltd.	NOUVEAU COMPOSÉ DE THIÉNO[2,3-d]PYRIMIDINE
AR065804A1 (es)	2007-03-23	2009-07-01	Smithkline Beecham Corp	Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
CN101684123B (zh) *	2008-09-27	2013-12-11	四川大学	2-甲酰胺基噻吩并吡啶衍生物制备方法及医药用途
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US8481547B2 (en) *	2009-12-18	2013-07-09	Janssen Pharmaceutica Nv	Substituted benzothiazole and benzoxazole derivatives useful as inhibitors of DPP-1
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PE20040539A1 (es)	2004-10-21
MXPA04011246A (es)	2005-06-03
AR040250A1 (es)	2005-03-23
NO20044599L (no)	2005-02-16
EA008706B1 (ru)	2007-06-29
EP1513516A1 (en)	2005-03-16
EP2008654A1 (en)	2008-12-31
EA200401541A1 (ru)	2005-06-30
DE60325051D1 (de)	2009-01-15
KR20050005548A (ko)	2005-01-13
AU2003237330A1 (en)	2003-12-22
BR0311605A (pt)	2005-02-22
DK1513516T3 (da)	2009-10-19
PL373424A1 (en)	2005-08-22
TWI296927B (en)	2008-05-21
CA2483890C (en)	2012-12-11
ES2318141T3 (es)	2009-05-01
HRP20041154A2 (en)	2005-06-30
RS105204A (en)	2006-12-15
EP1513516B1 (en)	2008-12-03
JP2005530816A (ja)	2005-10-13
US6964956B2 (en)	2005-11-15
CA2483890A1 (en)	2003-12-18
TW200401640A (en)	2004-02-01
US20050288285A1 (en)	2005-12-29
UY27834A1 (es)	2003-12-31
CN1649581A (zh)	2005-08-03
US20040053957A1 (en)	2004-03-18
CN100386329C (zh)	2008-05-07
US7405225B2 (en)	2008-07-29
WO2003103661A1 (en)	2003-12-18
JP4364120B2 (ja)	2009-11-11
ME00355B (me)	2010-06-30
JP2009102447A (ja)	2009-05-14
HK1080737A1 (en)	2006-05-04
MEP53508A (en)	2011-05-10
NZ537394A (en)	2006-12-22
IL164597A0 (en)	2005-12-18

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