ATE408398T1 - Nanopartikele für dna verabreichung zu einem zielorgan - Google Patents

Nanopartikele für dna verabreichung zu einem zielorgan

Info

Publication number
ATE408398T1
ATE408398T1 AT02767270T AT02767270T ATE408398T1 AT E408398 T1 ATE408398 T1 AT E408398T1 AT 02767270 T AT02767270 T AT 02767270T AT 02767270 T AT02767270 T AT 02767270T AT E408398 T1 ATE408398 T1 AT E408398T1
Authority
AT
Austria
Prior art keywords
nanoparticles
target organ
dna administration
dna
administration
Prior art date
Application number
AT02767270T
Other languages
English (en)
Inventor
Bernhard A Sabel
Christian Walz
Kerstin Ringe
Original Assignee
Nanodel Technologies Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanodel Technologies Gmbh filed Critical Nanodel Technologies Gmbh
Application granted granted Critical
Publication of ATE408398T1 publication Critical patent/ATE408398T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Wood Science & Technology (AREA)
  • Nanotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT02767270T 2002-07-29 2002-07-29 Nanopartikele für dna verabreichung zu einem zielorgan ATE408398T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2002/008434 WO2004017945A1 (en) 2002-07-29 2002-07-29 Nanoparticles for dna administration to a target organ

Publications (1)

Publication Number Publication Date
ATE408398T1 true ATE408398T1 (de) 2008-10-15

Family

ID=31896790

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02767270T ATE408398T1 (de) 2002-07-29 2002-07-29 Nanopartikele für dna verabreichung zu einem zielorgan

Country Status (10)

Country Link
US (1) US7402573B2 (de)
EP (1) EP1526840B1 (de)
JP (1) JP2006500015A (de)
AT (1) ATE408398T1 (de)
AU (1) AU2002331356A1 (de)
CA (1) CA2492807A1 (de)
DE (1) DE60229003D1 (de)
DK (1) DK1526840T3 (de)
ES (1) ES2314097T3 (de)
WO (1) WO2004017945A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60229003D1 (de) 2002-07-29 2008-10-30 Nanodel Technologies Gmbh Nanopartikele für dna verabreichung zu einem zielorgan
EP1661559A1 (de) * 2004-11-25 2006-05-31 NanoDel Technologies GmbH Verabreichungssystem hergestellt durch ein Miniemulsionsverfahren
PL1796650T3 (pl) * 2004-09-14 2009-06-30 Nanodel Tech Gmbh Nanocząstki zawierające dostarczające podłoże
WO2006056362A2 (en) * 2004-11-25 2006-06-01 Nanodel Technologies Gmbh Delivery vehicle manufactured by the miniemulsion method
WO2006130943A1 (en) * 2005-06-10 2006-12-14 The Governors Of The University Of Alberta Respirable dried powder formulation comprising drug loaded nanoparticles
EP1815851A1 (de) * 2006-02-03 2007-08-08 NanoDel Technologies GmbH Nanopartikel zur Arzneistoffverabreichung
CA2654593A1 (en) * 2006-06-08 2007-12-13 Bayer Schering Pharma Aktiengesellschaft Functionalized, solid polymer nanoparticles for diagnostic and therapeutic applications
JP4963221B2 (ja) * 2006-11-24 2012-06-27 公立大学法人横浜市立大学 シアノアクリレート系ポリマー粒子及びその製造方法
JP5224313B2 (ja) * 2007-02-27 2013-07-03 公立大学法人横浜市立大学 プラスミド送達用粒子
RU2617059C2 (ru) * 2014-11-11 2017-04-19 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова" (ФГБНУ НИИВС им. И.И. Мечникова) Способ получения амфифильных блок-сополимеров N,N-диметиламиноэтилметакрилата для доставки нуклеиновых кислот в живые клетки
JP2020517638A (ja) 2017-04-20 2020-06-18 エータイアー ファーマ， インコーポレイテッド 肺の炎症を治療するための組成物および方法
CN110913851B (zh) 2017-04-25 2023-08-25 伊斯切米克斯公司 治疗外伤性脑损伤的组合物和方法
CR20200653A (es) 2018-07-03 2021-02-11 Gilead Sciences Inc Anticuerpos que se dirigen al gp120 de vih y métodos de uso
EP3990476A1 (de) 2019-06-25 2022-05-04 Gilead Sciences, Inc. Flt3l-fc-fusionsproteine und verfahren zur verwendung
EP3999107A1 (de) 2019-07-16 2022-05-25 Gilead Sciences, Inc. Hiv-impfstoffe und verfahren zur herstellung und verwendung
CA3149557A1 (en) 2019-09-30 2021-04-08 Scott J. Balsitis Hbv vaccines and methods treating hbv
CA3128035A1 (en) 2020-08-13 2022-02-13 Bioasis Technologies, Inc. Combination therapies for delivery across the blood brain barrier
TW202406932A (zh) 2020-10-22 2024-02-16 美商基利科學股份有限公司 介白素2-Fc融合蛋白及使用方法
WO2024015741A1 (en) 2022-07-12 2024-01-18 Gilead Sciences, Inc. Hiv immunogenic polypeptides and vaccines and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69529054T2 (de) * 1994-02-28 2003-08-21 Nanopharm Ag System zur gezielten wirkstoffzufuhr, verfahren zu seiner herstellung und verwendung
WO1997003702A1 (en) * 1995-07-21 1997-02-06 Brown University Research Foundation A method for gene therapy using nucleic acid loaded polymeric microparticles
US6248720B1 (en) * 1996-07-03 2001-06-19 Brown University Research Foundation Method for gene therapy using nucleic acid loaded polymeric microparticles
WO1998056361A1 (en) * 1997-06-13 1998-12-17 Medinova Medical Consulting Gmbh Drug targeting system, method of its preparation and its use
US6265546B1 (en) * 1997-12-22 2001-07-24 Genset Prostate cancer gene
AU4373499A (en) * 1999-06-02 2000-12-28 Medinova Medical Consulting Gmbh Use of drug-loaded nanoparticles for the treatment of cancers
DE60229003D1 (de) 2002-07-29 2008-10-30 Nanodel Technologies Gmbh Nanopartikele für dna verabreichung zu einem zielorgan

Also Published As

Publication number Publication date
CA2492807A1 (en) 2004-03-04
EP1526840A1 (de) 2005-05-04
WO2004017945A1 (en) 2004-03-04
JP2006500015A (ja) 2006-01-05
DE60229003D1 (de) 2008-10-30
ES2314097T3 (es) 2009-03-16
AU2002331356A1 (en) 2004-03-11
US20050175710A1 (en) 2005-08-11
EP1526840B1 (de) 2008-09-17
US7402573B2 (en) 2008-07-22
DK1526840T3 (da) 2008-11-03

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties
REN Ceased due to non-payment of the annual fee