ATE39927T1 - -9-fluoro-6,7-dihydro-5-methyl-1-oxo-8 substituierte-1h,5h-benzo (ij>-chinolizin-2carboxyl-s|ure; ihre derivate und verfahren zu ihrer herstellung. - Google Patents
-9-fluoro-6,7-dihydro-5-methyl-1-oxo-8 substituierte-1h,5h-benzo (ij>-chinolizin-2carboxyl-s|ure; ihre derivate und verfahren zu ihrer herstellung.Info
- Publication number
- ATE39927T1 ATE39927T1 AT85305125T AT85305125T ATE39927T1 AT E39927 T1 ATE39927 T1 AT E39927T1 AT 85305125 T AT85305125 T AT 85305125T AT 85305125 T AT85305125 T AT 85305125T AT E39927 T1 ATE39927 T1 AT E39927T1
- Authority
- AT
- Austria
- Prior art keywords
- fluoro
- benzo
- dihydro
- oxo
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/632,999 US4550103A (en) | 1984-07-20 | 1984-07-20 | Antibacterial 1-oxo-benzoquinolizine-2-carboxylic acids |
EP85305125A EP0174077B1 (de) | 1984-07-20 | 1985-07-18 | -9-fluoro-6,7-dihydro-5-methyl-1-oxo-8 substituierte-1H,5H-benzo [ij]-chinolizin-2-carboxyl-Säure; ihre Derivate und Verfahren zu ihrer Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE39927T1 true ATE39927T1 (de) | 1989-01-15 |
Family
ID=24537866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT85305125T ATE39927T1 (de) | 1984-07-20 | 1985-07-18 | -9-fluoro-6,7-dihydro-5-methyl-1-oxo-8 substituierte-1h,5h-benzo (ij>-chinolizin-2carboxyl-s|ure; ihre derivate und verfahren zu ihrer herstellung. |
Country Status (5)
Country | Link |
---|---|
US (1) | US4550103A (de) |
EP (1) | EP0174077B1 (de) |
JP (1) | JPS6163677A (de) |
AT (1) | ATE39927T1 (de) |
DE (1) | DE3567462D1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4638067A (en) * | 1982-09-09 | 1987-01-20 | Warner-Lambert Co. | Antibacterial agents |
US4617308A (en) * | 1985-01-25 | 1986-10-14 | Warner-Lambert Company | 7-substituted amino-1-aryl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and derivatives thereof as antibacterial agents |
JP2837953B2 (ja) * | 1991-03-22 | 1998-12-16 | フイリツプス ピトローリアム カンパニー | ガラス繊維強化グラフト化枝分れ高級α―オレフィン |
US5347017A (en) * | 1993-07-07 | 1994-09-13 | Warner-Lambert Company | Process for chiral 3-(1-amino-1,1-bisalkylmethyl)-1-substituted-pyrrolidines |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5630964A (en) * | 1979-08-22 | 1981-03-28 | Kyorin Pharmaceut Co Ltd | Novel substituted quinolinecarboxylic acid and its preparation |
JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
NO156828C (no) * | 1980-11-10 | 1987-12-02 | Otsuka Pharma Co Ltd | Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser. |
PH22140A (en) * | 1982-06-29 | 1988-06-01 | Daiichi Seiyaku Co | Tricyclic compounds |
US4472406A (en) * | 1982-11-12 | 1984-09-18 | Riker Laboratories, Inc. | Antimicrobial 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H-benzo [ij]quinolizine-2-carboxylic acids and derivatives |
-
1984
- 1984-07-20 US US06/632,999 patent/US4550103A/en not_active Expired - Fee Related
-
1985
- 1985-07-18 EP EP85305125A patent/EP0174077B1/de not_active Expired
- 1985-07-18 DE DE8585305125T patent/DE3567462D1/de not_active Expired
- 1985-07-18 AT AT85305125T patent/ATE39927T1/de not_active IP Right Cessation
- 1985-07-19 JP JP60158485A patent/JPS6163677A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US4550103A (en) | 1985-10-29 |
DE3567462D1 (en) | 1989-02-16 |
EP0174077A1 (de) | 1986-03-12 |
EP0174077B1 (de) | 1989-01-11 |
JPS6163677A (ja) | 1986-04-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK140996A (da) | Fremgangsmåde til fremstilling af 2,3,4,5-tetraflour-6-alkyl-benzoesyreforbindelser | |
TW289020B (de) | ||
ATE44954T1 (de) | Carbostyrilderivat und verfahren zu seiner herstellung. | |
ATE25245T1 (de) | Chinoloncarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel. | |
IE863104L (en) | Quinolone derivatives | |
EP0266576A3 (de) | 1-Tert-alkyl-substituierte Naphthyridin- und Chinolincarbonsäure als antibakterielle Mittel | |
EP0181588A3 (de) | Alkyl-l-cyclopropyl-l,4-dihydro-4-oxo-3-chinolincarbonsäuren, Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel | |
ATE136298T1 (de) | Chinoloncarbonsäurederivate, verfahren zu ihrer herstellung sowie ihre verwendung als antivirale mittel | |
YU1396A (sh) | 2,9-disupstituisani purin-6-oni, postupak za njihovo pripremanje i njihova primena u lekovima | |
ES8800160A1 (es) | Procedimiento de obtencion de acidos quinolincarboxilicos con propiedades antibacteriales. | |
DE2967701D1 (de) | A-21978 genannte antibiotische mischung, verfahren zu ihrer herstellung, ihre pharmazeutischen zusammensetzungen und produzierender mikroorganismus. | |
ES8500931A1 (es) | Procedimiento para la obtencion de acidos quinoloncarboxilicos | |
EP0230053A3 (de) | 7-(Substituierte)Piperazinyl-1-äthyl-6-fluor-1,4-dihydro-4-oxo-3-chinolinkarbonsäure | |
DE59009705D1 (de) | Verfahren zur Herstellung von 2,7-Diazabicyclo(3.3.0)octanen. | |
FR2484418B1 (fr) | Nouveaux derives d'acide isocyanurique, utiles notamment comme agents cytostatiques, et leur procede de preparation | |
ES476917A1 (es) | Un procedimiento para la preparacion de derivados de acido -4-piridon-3-carboxilico. | |
ATE1609T1 (de) | Sisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. | |
ATE39927T1 (de) | -9-fluoro-6,7-dihydro-5-methyl-1-oxo-8 substituierte-1h,5h-benzo (ij>-chinolizin-2carboxyl-s|ure; ihre derivate und verfahren zu ihrer herstellung. | |
ATE55603T1 (de) | N-alkyl-2,6-dimethylmorpholinio-carbonsaeureamid salze, verfahren zu ihrer herstellung und ihre verwendung als fungizide. | |
BE887752A (fr) | Derives de l'acide 7-oxo-1-azabicyclo (3,2,0) hept-2-ene-2-carboxylique, leur procede de preparation et leur application notamment comme antibiotiques | |
ES8301244A1 (es) | Procedimiento para la obtencion de derivados de sisomicina. | |
ATE66610T1 (de) | Primycin enthaltendes kolloidales grundgel, verfahren zu dessen herstellung, dieses grundgel enthaltende pharmazeutische und pharmako- kosmetische kompositionen. | |
ATE32897T1 (de) | Pyrazolo(3,4,5-kl)acridinderivate, pharmazeutische zubereitungen die sie enthalten und verfahren zu ihrer herstellung. | |
ATE77621T1 (de) | 3-perfluoroalkyl-isoxazol-5-yl-oxycarbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als herbizide. | |
ATE236131T1 (de) | Optisch aktives 2-nitroimidazolderivat, verfahren zu seiner herstellung und ein intermediat zu seiner herstellung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |