ATE375806T1 - Verbesserungen in oder bezüglich zu kontrastmittel - Google Patents

Verbesserungen in oder bezüglich zu kontrastmittel

Info

Publication number: ATE375806T1
Authority: AT; Austria
Prior art keywords: dispersed; gas; preparations; perfusion; material present
Prior art date: 1998-04-22

Application number

AT99918133T

Other languages

English (en)

Inventor

Morten Eriksen

Helge Tolleshaug

Roald Skurtveit

Alan Cuthbertson

Jonny Ostensen

Sigmund Frigstad

Pal Rongved

Original Assignee

Ge Healthcare As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-04-22

Filing date

1999-04-22

Publication date

2007-11-15

1999-04-22 Application filed by Ge Healthcare As filed Critical Ge Healthcare As

2007-11-15 Application granted granted Critical

2007-11-15 Publication of ATE375806T1 publication Critical patent/ATE375806T1/de

Links

239000002872 contrast media Substances 0.000 title abstract 2
230000010412 perfusion Effects 0.000 abstract 3
238000002360 preparation method Methods 0.000 abstract 3
OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 abstract 2
238000001727 in vivo Methods 0.000 abstract 2
239000000463 material Substances 0.000 abstract 2
239000002126 C01EB10 - Adenosine Substances 0.000 abstract 1
229960005305 adenosine Drugs 0.000 abstract 1
239000012736 aqueous medium Substances 0.000 abstract 1
230000000747 cardiac effect Effects 0.000 abstract 1
238000009792 diffusion process Methods 0.000 abstract 1
238000003384 imaging method Methods 0.000 abstract 1
230000002107 myocardial effect Effects 0.000 abstract 1
210000004165 myocardium Anatomy 0.000 abstract 1
239000007764 o/w emulsion Substances 0.000 abstract 1
239000003071 vasodilator agent Substances 0.000 abstract 1
238000012800 visualization Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Physics & Mathematics (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Acoustics & Sound (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Radiology & Medical Imaging (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)
Light Receiving Elements (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Magnetic Resonance Imaging Apparatus (AREA)

AT99918133T 1998-04-22 1999-04-22 Verbesserungen in oder bezüglich zu kontrastmittel ATE375806T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9808599.6A GB9808599D0 (en)	1998-04-22	1998-04-22	Improvements in or realting to contrast agents

Publications (1)

Publication Number	Publication Date
ATE375806T1 true ATE375806T1 (de)	2007-11-15

Family

ID=10830802

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99918133T ATE375806T1 (de)	1998-04-22	1999-04-22	Verbesserungen in oder bezüglich zu kontrastmittel

Country Status (17)

Country	Link
US (1)	US20040146462A1 (de)
EP (1)	EP1073473B1 (de)
JP (1)	JP2002512206A (de)
KR (1)	KR20010042915A (de)
CN (1)	CN1306442A (de)
AT (1)	ATE375806T1 (de)
AU (1)	AU3617299A (de)
BR (1)	BR9909822A (de)
CA (1)	CA2329175A1 (de)
DE (1)	DE69937341D1 (de)
GB (1)	GB9808599D0 (de)
HU (1)	HUP0102878A3 (de)
IL (1)	IL139147A0 (de)
NO (1)	NO20005250L (de)
PL (1)	PL343464A1 (de)
WO (1)	WO1999053963A1 (de)
ZA (1)	ZA200005789B (de)

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US5804162A (en) *	1995-06-07	1998-09-08	Alliance Pharmaceutical Corp.	Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
DE10119522A1 (de) *	2001-04-20	2002-12-05	Innovacell Biotechnologie Gmbh	Herstellung und Anwendung einer Suspensionszusammensetzung mit einem Ultraschall-Kontrastmittel
EP1572001A1 (de)	2002-11-29	2005-09-14	Amersham Health AS	Ultraschallauflösende methode
KR101076053B1 (ko)	2003-02-04	2011-10-21	브라코 인터내셔날 비.브이.	초음파 조영제 및 그것의 제조방법
US20070128117A1 (en) *	2003-02-04	2007-06-07	Bracco International B.V.	Ultrasound contrast agents and process for the preparation thereof
AU2004308756B2 (en) *	2003-12-22	2010-06-24	Bracco Suisse S.A.	Gas-filled microvesicle assembly for contrast imaging
EP1696965B1 (de) *	2003-12-22	2014-12-10	Bracco Suisse SA	Anordnung aus gasgefüllten mikrovesikeln mit wirkstoff für die kontrastdarstellung
JP4837663B2 (ja)	2004-08-18	2011-12-14	ブラッコ・シュイス・ソシエテ・アノニム	造影画像化のためのガス充填微小胞組成物
US8153435B1 (en)	2005-03-30	2012-04-10	Tracer Detection Technology Corp.	Methods and articles for identifying objects using encapsulated perfluorocarbon tracers
CN100453050C (zh) *	2005-09-21	2009-01-21	北京市肿瘤防治研究所	提高超声造影图像分辨力的方法和超声造影成像仪
US20080255266A1 (en) *	2007-04-10	2008-10-16	Gc Corporation	Dental paste composition having x-ray imaging property
JP4279328B2 (ja) *	2007-05-07	2009-06-17	株式会社日立製作所	超音波撮像システム
US20110158909A1 (en) *	2008-02-01	2011-06-30	Trustees Of Boston University	Cationic Contrast Agents and Methods of Use Thereof
US20110110863A1 (en) *	2008-05-02	2011-05-12	Celsense, Inc.	Compositions and methods for producing emulsions for nuclear magnetic resonance techniques and other applications
EP2470287A4 (de)	2009-08-28	2015-01-21	Univ Columbia	Systeme, verfahren und vorrichtungen zur herstellung gasgefüllter mikroblasen
DE102011005444A1 (de) *	2011-03-11	2012-09-13	Innora Gmbh	Festes, negatives Röntgenkontrastmittel zur Darstellung des Gastrointestinaltraktes
ES2951663T3 (es)	2013-09-27	2023-10-24	Exact Therapeutics As	Administración de fármacos
JOP20200052A1 (ar)	2013-12-19	2017-06-16	Bayer Pharma AG	بيبريدينيل تتراهيدرو كوينولينات مستبدلة واستخدامها كمعضدات مستقبل أدريني ألفا- 2c
WO2019014070A1 (en) *	2017-07-09	2019-01-17	The Board Of Trustees Of The Leland Stanford Junior University	ULTRASOUND IMAGING COMPRISING A SPECTRAL COMPOSITION FOR TAVELURE REDUCTION
WO2019046955A1 (en) *	2017-09-07	2019-03-14	Imbiotechnologies Ltd.	EMBOLIC AGENTS SENSITIVE TO SONO
CN108586300B (zh) *	2018-03-28	2020-03-17	成都福柯斯医药技术有限公司	一种s-碘化丁酰硫代胆碱的合成方法
EP4048231A1 (de)	2019-10-25	2022-08-31	Exact Therapeutics As	Behandlung von bauchspeicheldrüsenkrebs
GB2595513B (en)	2020-05-29	2023-03-29	Act Therapeutics Ltd	Treatment of infections
US11801058B2 (en) *	2021-03-04	2023-10-31	Accumedical Beijing Ltd.	Liquid embolic compositions
GB2605422A (en)	2021-03-31	2022-10-05	Act Therapeutics Ltd	Treatment of the central nervous system
GB2605996A (en)	2021-04-21	2022-10-26	Act Therapeutics Ltd	Enhancement of treatment with immunotherapeutic agents
EP4261786A1 (de) *	2022-03-28	2023-10-18	Tata Consultancy Services Limited	Verfahren und system zur perfusionsbildgebung mit niedrigdosierter röntgencomputertomographie

Family Cites Families (11)

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Publication number	Priority date	Publication date	Assignee	Title
US5580575A (en) *	1989-12-22	1996-12-03	Imarx Pharmaceutical Corp.	Therapeutic drug delivery systems
US5228446A (en) *	1989-12-22	1993-07-20	Unger Evan C	Gas filled liposomes and their use as ultrasonic contrast agents
US5776429A (en) *	1989-12-22	1998-07-07	Imarx Pharmaceutical Corp.	Method of preparing gas-filled microspheres using a lyophilized lipids
US5716597A (en) *	1993-06-04	1998-02-10	Molecular Biosystems, Inc.	Emulsions as contrast agents and method of use
WO1995003835A1 (en) *	1993-07-30	1995-02-09	Alliance Pharmaceutical Corp.	Stabilized microbubble compositions for ultrasound
NO940711D0 (no) *	1994-03-01	1994-03-01	Nycomed Imaging As	Preparation of gas-filled microcapsules and contrasts agents for diagnostic imaging
US5846517A (en) *	1996-09-11	1998-12-08	Imarx Pharmaceutical Corp.	Methods for diagnostic imaging using a renal contrast agent and a vasodilator
NZ335265A (en) *	1996-10-21	2000-07-28	Nycomed Imaging As	Gas containing contrast agents that may be co-administered with vasodilator drugs to enhance differences in return signal intensity from normal and hypoperfused myocardial tissue contrast agents
EP0946202B1 (de) *	1996-10-28	2003-09-10	Amersham Health AS	Kontrastmittel
WO1998018495A2 (en) *	1996-10-28	1998-05-07	Marsden, John, Christopher	Improvements in or relating to diagnostic/therapeutic agents
EP0963209A2 (de) *	1996-10-28	1999-12-15	Marsden, John Christopher	Verbesserungen in oder an diagnostischen/ therapeutischen mitteln

1998
- 1998-04-22 GB GBGB9808599.6A patent/GB9808599D0/en not_active Ceased
1999
- 1999-04-22 JP JP2000544366A patent/JP2002512206A/ja not_active Abandoned
- 1999-04-22 AU AU36172/99A patent/AU3617299A/en not_active Abandoned
- 1999-04-22 KR KR1020007011727A patent/KR20010042915A/ko not_active Application Discontinuation
- 1999-04-22 CA CA002329175A patent/CA2329175A1/en not_active Abandoned
- 1999-04-22 HU HU0102878A patent/HUP0102878A3/hu unknown
- 1999-04-22 DE DE69937341T patent/DE69937341D1/de not_active Expired - Lifetime
- 1999-04-22 AT AT99918133T patent/ATE375806T1/de not_active IP Right Cessation
- 1999-04-22 WO PCT/GB1999/001221 patent/WO1999053963A1/en active IP Right Grant
- 1999-04-22 IL IL13914799A patent/IL139147A0/xx unknown
- 1999-04-22 PL PL99343464A patent/PL343464A1/xx unknown
- 1999-04-22 BR BR9909822-9A patent/BR9909822A/pt not_active IP Right Cessation
- 1999-04-22 EP EP99918133A patent/EP1073473B1/de not_active Expired - Lifetime
- 1999-04-22 CN CN99807622A patent/CN1306442A/zh active Pending
2000
- 2000-10-18 ZA ZA200005789A patent/ZA200005789B/xx unknown
- 2000-10-19 NO NO20005250A patent/NO20005250L/no not_active Application Discontinuation
2003
- 2003-11-19 US US10/717,196 patent/US20040146462A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20040146462A1 (en)	2004-07-29
NO20005250L (no)	2000-12-18
ZA200005789B (en)	2001-07-30
HUP0102878A3 (en)	2002-12-28
WO1999053963A1 (en)	1999-10-28
IL139147A0 (en)	2001-11-25
CN1306442A (zh)	2001-08-01
HUP0102878A2 (hu)	2002-03-28
PL343464A1 (en)	2001-08-13
EP1073473A1 (de)	2001-02-07
EP1073473B1 (de)	2007-10-17
NO20005250D0 (no)	2000-10-19
JP2002512206A (ja)	2002-04-23
AU3617299A (en)	1999-11-08
DE69937341D1 (de)	2007-11-29
CA2329175A1 (en)	1999-10-28
BR9909822A (pt)	2000-12-19
KR20010042915A (ko)	2001-05-25
GB9808599D0 (en)	1998-06-24

Legal Events

Date	Code	Title	Description
2008-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE375806T1 (de)	2007-11-15	Verbesserungen in oder bezüglich zu kontrastmittel
WO1998017324A3 (en)	1998-06-25	Improvements in or relating to contrast agents
EE03235B1 (et)	1999-12-15	Emulsioonvorm, selle valmistamise protsess ja kasutamine
NO20031249D0 (no)	2003-03-18	Emulsjonspreparater samt konsentrater derav
BR9610089A (pt)	1999-01-05	Microemulsão não tóxica de óleo em água ou bicontínua processo para sua preparação e uso da mesma
IT1246350B (it)	1994-11-17	Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili
NO308448B1 (no)	2000-09-18	Mikrosfærer samt fremstilling, preparater og anvendelse derav
BRPI0414128A (pt)	2006-10-31	sistema e método para aumento de mamas
EA200400242A1 (ru)	2004-12-30	Фармацевтические композиции, содержащие бета-лапахон или его производные или аналоги, и способы их применения
IT1174474B (it)	1987-07-01	Procedimento per la preparazione di formulazione galeniche particolarmente per uso farmaceutico, dietetico, cosmetico e diagnostico
CA2383600A1 (en)	2001-03-29	Method for determining viability of a myocardial segment
Sugiyama et al.	1985	Histamine-release induced by 7S nervegrowth factor of mouse submandibular salivary glands
JP2001515053A (ja)	2001-09-18	造影剤におけるまたは造影剤に関する改良
GB9808582D0 (en)	1998-06-24	Improvements in or relating to contrast agents
Møller et al.	1998	Neurohumoral fluid regulation in chronic liver disease
Flynn et al.	1995	Sarafotoxin S6c elicits a non-ETA or non-ETB-mediated pressor response in the pithed rat
DK1058544T3 (da)	2005-03-14	Inhibition af TNF-aktivitet med præparater, der omfatter heparin og oplöselige TNF-receptorer
WO2003072606A3 (en)	2003-12-18	Galectin-8and functional derivatives as binding agents for cd44 glycoproteins and methods of use
RU2000100373A (ru)	2002-01-10	Природные противоопухолевые или противовирусные вещества и их применение
Allison et al.	1986	Effects of enprostil on platelets, endothelial cells, and other cell types, and second messenger systems by which these effects are mediated
Kayigil et al.	1996	Electromyographic changes of corpus cavernosum due to papaverine and nitroprusside in veno-occlusive dysfunction
KR900017599A (ko)	1990-12-19	종양 치료용 약학 조성물
Coats	1995	ACE inhibitors after myocardial infarction: selection and treatment for all.
Evans et al.	1987	Effects of chronic delta-9-THC treatment on cardiac beta-adrenoceptors in rats
GR890100737A (el)	1990-12-31	Μέ?οδος παρασκευής μιας φαρμακευτικής συν?έσεως δι'οφ?αλμική χρήσιν η οποία περιλαμβάνει ένα υδατοδιαλυτό άλας δια προσ?ήκης οξέος ιμποπαμίνης.