ATE359513T1 - Hochdurchsatzscreening von verbindungen für biologische wirksamkeit - Google Patents
Hochdurchsatzscreening von verbindungen für biologische wirksamkeitInfo
- Publication number
- ATE359513T1 ATE359513T1 AT01944494T AT01944494T ATE359513T1 AT E359513 T1 ATE359513 T1 AT E359513T1 AT 01944494 T AT01944494 T AT 01944494T AT 01944494 T AT01944494 T AT 01944494T AT E359513 T1 ATE359513 T1 AT E359513T1
- Authority
- AT
- Austria
- Prior art keywords
- target
- compounds
- candidate compound
- substrate
- candidate
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21126800P | 2000-06-13 | 2000-06-13 | |
| US29453101P | 2001-05-30 | 2001-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE359513T1 true ATE359513T1 (de) | 2007-05-15 |
Family
ID=26906001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01944494T ATE359513T1 (de) | 2000-06-13 | 2001-06-13 | Hochdurchsatzscreening von verbindungen für biologische wirksamkeit |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20030219825A1 (de) |
| EP (1) | EP1360495B1 (de) |
| JP (1) | JP2004503249A (de) |
| AT (1) | ATE359513T1 (de) |
| AU (1) | AU2001266902A1 (de) |
| DE (1) | DE60127867T2 (de) |
| ES (1) | ES2284655T3 (de) |
| WO (1) | WO2001096597A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004092903A2 (en) * | 2003-04-09 | 2004-10-28 | Discovery Partners International | Spot finding algorithm using image recognition software |
| DOP2006000008A (es) * | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1 |
| WO2007100618A2 (en) * | 2006-02-23 | 2007-09-07 | Atto Bioscience | Novel cell-based phosphodiesterase assays |
| EP2146210A1 (de) | 2008-04-07 | 2010-01-20 | Arena Pharmaceuticals, Inc. | Verfahren zur Verwendung eines AG-Protein-gekoppelten Rezeptors zur Identifikation von Peptid-YY (PPY)-Sekretagogen sowie Verbindungen zur Behandlung durch PYY modulierter Leiden |
| CN101949819B (zh) * | 2010-09-16 | 2013-05-01 | 北京优纳科技有限公司 | 一种基于图像识别的细胞计数方法 |
| KR20180117529A (ko) | 2017-04-19 | 2018-10-29 | 주식회사 프로티나 | 단백질-단백질 상호작용 분석에 의한 약물 반응성 예측 방법 |
| WO2018194406A1 (ko) * | 2017-04-19 | 2018-10-25 | 주식회사 프로티나 | 단백질-단백질 상호작용 분석 방법 및 장치 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4138621A1 (de) * | 1991-11-25 | 1993-06-17 | Boehringer Ingelheim Int | Verfahren zum screenen von substanzen mit modulierender wirkung auf einen rezeptorabhaengigen zellulaeren signaluebertragungsweg |
| US5670113A (en) * | 1991-12-20 | 1997-09-23 | Sibia Neurosciences, Inc. | Automated analysis equipment and assay method for detecting cell surface protein and/or cytoplasmic receptor function using same |
| AU2953295A (en) * | 1994-07-01 | 1996-01-25 | W.R. Grace & Co.-Conn. | Hepatocyte test kit |
| JPH11504507A (ja) * | 1995-03-31 | 1999-04-27 | ノボ ノルディスク アクティーゼルスカブ | 生物学的に活性な基質を、生きている細胞に関するこれらの影響によって同定するための方法 |
| US5780258A (en) * | 1996-09-04 | 1998-07-14 | Tularik, Inc | Drug screens for regulators of the expression of the obese gene |
| EP1036324B1 (de) * | 1997-11-27 | 2004-06-23 | Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. | Identifizierung und charakterisierung von interagierenden molekülen mittels automatisierter interagierender paarung |
| US5976813A (en) * | 1997-12-12 | 1999-11-02 | Abbott Laboratories | Continuous format high throughput screening |
| WO2000017643A2 (en) * | 1998-09-18 | 2000-03-30 | Cellomics, Inc. | A system for cell-based screening |
| AU2001265092A1 (en) * | 2000-06-02 | 2001-12-17 | Regents Of The University Of California | Profiling of protease specificity using combinatorial fluorogenic substrate libraries |
-
2001
- 2001-06-13 ES ES01944494T patent/ES2284655T3/es not_active Expired - Lifetime
- 2001-06-13 AT AT01944494T patent/ATE359513T1/de not_active IP Right Cessation
- 2001-06-13 AU AU2001266902A patent/AU2001266902A1/en not_active Abandoned
- 2001-06-13 US US10/297,976 patent/US20030219825A1/en not_active Abandoned
- 2001-06-13 DE DE60127867T patent/DE60127867T2/de not_active Expired - Lifetime
- 2001-06-13 EP EP01944494A patent/EP1360495B1/de not_active Expired - Lifetime
- 2001-06-13 WO PCT/US2001/019033 patent/WO2001096597A2/en active Search and Examination
- 2001-06-13 JP JP2002510710A patent/JP2004503249A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001096597A2 (en) | 2001-12-20 |
| US20030219825A1 (en) | 2003-11-27 |
| JP2004503249A (ja) | 2004-02-05 |
| DE60127867D1 (de) | 2007-05-24 |
| ES2284655T3 (es) | 2007-11-16 |
| DE60127867T2 (de) | 2008-01-17 |
| AU2001266902A1 (en) | 2001-12-24 |
| EP1360495B1 (de) | 2007-04-11 |
| EP1360495A2 (de) | 2003-11-12 |
| WO2001096597A3 (en) | 2003-09-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |