ATE352312T1 - Kombinierte verwendung einer glp-1-verbindung und eines aldose reduktase inhibitors - Google Patents
Kombinierte verwendung einer glp-1-verbindung und eines aldose reduktase inhibitorsInfo
- Publication number
- ATE352312T1 ATE352312T1 AT02787467T AT02787467T ATE352312T1 AT E352312 T1 ATE352312 T1 AT E352312T1 AT 02787467 T AT02787467 T AT 02787467T AT 02787467 T AT02787467 T AT 02787467T AT E352312 T1 ATE352312 T1 AT E352312T1
- Authority
- AT
- Austria
- Prior art keywords
- glp
- compound
- combined use
- reductase inhibitor
- aldose reductase
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200101969 | 2001-12-29 | ||
DKPA200200760 | 2002-05-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE352312T1 true ATE352312T1 (de) | 2007-02-15 |
Family
ID=26069120
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02787467T ATE352312T1 (de) | 2001-12-29 | 2002-12-20 | Kombinierte verwendung einer glp-1-verbindung und eines aldose reduktase inhibitors |
Country Status (8)
Country | Link |
---|---|
US (3) | US20030144206A1 (de) |
EP (2) | EP1790353A1 (de) |
JP (1) | JP2005516968A (de) |
AT (1) | ATE352312T1 (de) |
AU (1) | AU2002351753A1 (de) |
DE (1) | DE60217918T2 (de) |
ES (1) | ES2280596T3 (de) |
WO (1) | WO2003059372A2 (de) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7790681B2 (en) | 2002-12-17 | 2010-09-07 | Amylin Pharmaceuticals, Inc. | Treatment of cardiac arrhythmias with GLP-1 receptor ligands |
US20040209803A1 (en) * | 2002-12-19 | 2004-10-21 | Alain Baron | Compositions for the treatment and prevention of nephropathy |
US20040242568A1 (en) * | 2003-03-25 | 2004-12-02 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
US7678909B1 (en) | 2003-08-13 | 2010-03-16 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US7790736B2 (en) | 2003-08-13 | 2010-09-07 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US7169926B1 (en) | 2003-08-13 | 2007-01-30 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US7790734B2 (en) | 2003-09-08 | 2010-09-07 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
JP2006514649A (ja) * | 2003-12-17 | 2006-05-11 | アミリン・ファーマシューティカルズ,インコーポレイテッド | 腎症の治療および予防のための組成物 |
EP1581246B1 (de) | 2003-12-17 | 2013-01-16 | Amylin Pharmaceuticals, LLC | Zusammensetzungen zur behandlung und prevention von nephropathie |
US7732446B1 (en) | 2004-03-11 | 2010-06-08 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
CN102134229B (zh) | 2004-03-15 | 2020-08-04 | 武田药品工业株式会社 | 二肽基肽酶抑制剂 |
WO2005118555A1 (en) | 2004-06-04 | 2005-12-15 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
EP1750862B1 (de) | 2004-06-04 | 2011-01-05 | Teva Pharmaceutical Industries Ltd. | Irbesartan enthaltende pharmazeutische zusammensetzung |
WO2006019965A2 (en) | 2004-07-16 | 2006-02-23 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
WO2006019851A1 (en) * | 2004-07-23 | 2006-02-23 | Eli Lilly And Company | Methods for diagnosing and treating diabetic microvascular complications |
WO2006068978A2 (en) | 2004-12-21 | 2006-06-29 | Takeda Pharmaceutial Company Limited | Dipeptidyl peptidase inhibitors |
US20080096915A1 (en) * | 2005-01-13 | 2008-04-24 | Greenberg Traurig LLP | Compositions for the treatment of metabolic disorders |
US7905868B2 (en) | 2006-08-23 | 2011-03-15 | Medtronic Minimed, Inc. | Infusion medium delivery device and method with drive device for driving plunger in reservoir |
US8512288B2 (en) | 2006-08-23 | 2013-08-20 | Medtronic Minimed, Inc. | Infusion medium delivery device and method with drive device for driving plunger in reservoir |
US8277415B2 (en) | 2006-08-23 | 2012-10-02 | Medtronic Minimed, Inc. | Infusion medium delivery device and method with drive device for driving plunger in reservoir |
US7955305B2 (en) | 2005-05-06 | 2011-06-07 | Medtronic Minimed, Inc. | Needle inserter and method for infusion device |
US8840586B2 (en) | 2006-08-23 | 2014-09-23 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir filling and infusion medium delivery |
US20080097291A1 (en) | 2006-08-23 | 2008-04-24 | Hanson Ian B | Infusion pumps and methods and delivery devices and methods with same |
US8137314B2 (en) | 2006-08-23 | 2012-03-20 | Medtronic Minimed, Inc. | Infusion medium delivery device and method with compressible or curved reservoir or conduit |
PL1942898T5 (pl) | 2005-09-14 | 2014-10-31 | Takeda Pharmaceuticals Co | Inhibitory peptydazy dipeptydylowej do leczenia cukrzycy |
CN102675221A (zh) | 2005-09-16 | 2012-09-19 | 武田药品工业株式会社 | 用于制备嘧啶二酮衍生物的方法中的中间体 |
ES2336575T3 (es) * | 2005-09-22 | 2010-04-14 | Biocompatibles Uk Limited | Polipeptidos de fusion glp-1 (peptido-1 similar al glucagon) con resistencia aumentada a la peptidasa. |
EP1968644B1 (de) | 2005-12-16 | 2012-06-27 | Nektar Therapeutics | Polymerkonjugate von glp-1 |
US11027058B2 (en) | 2006-02-09 | 2021-06-08 | Deka Products Limited Partnership | Infusion pump assembly |
US11497846B2 (en) | 2006-02-09 | 2022-11-15 | Deka Products Limited Partnership | Patch-sized fluid delivery systems and methods |
US11364335B2 (en) | 2006-02-09 | 2022-06-21 | Deka Products Limited Partnership | Apparatus, system and method for fluid delivery |
ATE504325T1 (de) | 2006-02-09 | 2011-04-15 | Deka Products Lp | Systeme zur abgabe von flüssigkeiten in patch- grösse |
US11478623B2 (en) | 2006-02-09 | 2022-10-25 | Deka Products Limited Partnership | Infusion pump assembly |
WO2007112347A1 (en) | 2006-03-28 | 2007-10-04 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
ATE444741T1 (de) * | 2006-05-10 | 2009-10-15 | Biocompatibles Uk Ltd | Glp-1 peptide enthaltende kugelförmige mikrokapseln, deren produktion und deren verwendung |
US7794434B2 (en) | 2006-08-23 | 2010-09-14 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir filling and infusion medium delivery |
US7736338B2 (en) | 2006-08-23 | 2010-06-15 | Medtronic Minimed, Inc. | Infusion medium delivery system, device and method with needle inserter and needle inserter device and method |
US7828764B2 (en) | 2006-08-23 | 2010-11-09 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir filling and infusion medium delivery |
US7811262B2 (en) | 2006-08-23 | 2010-10-12 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir filling and infusion medium delivery |
GEP20125701B (en) * | 2006-09-13 | 2012-12-10 | Takeda Pharmaceuticals Co | Application of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2h-pyrimidin-1-ylmethyl]-4-fluoro-benzonitrile |
US8324383B2 (en) | 2006-09-13 | 2012-12-04 | Takeda Pharmaceutical Company Limited | Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile |
TW200838536A (en) | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
US8686051B2 (en) * | 2007-01-29 | 2014-04-01 | Vlife Sciences Technologies Pvt. Ltd. | Pharmaceutical composition for treatment of diabetic complications |
US8093236B2 (en) | 2007-03-13 | 2012-01-10 | Takeda Pharmaceuticals Company Limited | Weekly administration of dipeptidyl peptidase inhibitors |
EP1972349A1 (de) * | 2007-03-21 | 2008-09-24 | Biocompatibles UK Limited | Mit Polymer(en) konjugierte GLP-1-Fusionspeptide, ihre Herstellung und Verwendung |
EP1975176A1 (de) * | 2007-03-27 | 2008-10-01 | Biocompatibles UK Limited | Neue GLP-1-Fusionspeptide, ihre Herstellung und Verwendung |
US7963954B2 (en) | 2007-04-30 | 2011-06-21 | Medtronic Minimed, Inc. | Automated filling systems and methods |
US8434528B2 (en) | 2007-04-30 | 2013-05-07 | Medtronic Minimed, Inc. | Systems and methods for reservoir filling |
US7959715B2 (en) | 2007-04-30 | 2011-06-14 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
EP2146760B1 (de) | 2007-04-30 | 2018-10-10 | Medtronic MiniMed, Inc. | Reservoir-füllung, blasenkontrolle und infusionsmedium-abgabesysteme und verfahren dafür |
US8597243B2 (en) | 2007-04-30 | 2013-12-03 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
US8613725B2 (en) | 2007-04-30 | 2013-12-24 | Medtronic Minimed, Inc. | Reservoir systems and methods |
US8323250B2 (en) | 2007-04-30 | 2012-12-04 | Medtronic Minimed, Inc. | Adhesive patch systems and methods |
CN110251769B (zh) | 2007-12-31 | 2022-04-01 | 德卡产品有限公司 | 输注泵组件 |
EP2244765B1 (de) | 2007-12-31 | 2019-08-14 | DEKA Products Limited Partnership | Infusionspumpenanordnung |
US10080704B2 (en) | 2007-12-31 | 2018-09-25 | Deka Products Limited Partnership | Apparatus, system and method for fluid delivery |
US9456955B2 (en) | 2007-12-31 | 2016-10-04 | Deka Products Limited Partnership | Apparatus, system and method for fluid delivery |
US8881774B2 (en) | 2007-12-31 | 2014-11-11 | Deka Research & Development Corp. | Apparatus, system and method for fluid delivery |
US10188787B2 (en) | 2007-12-31 | 2019-01-29 | Deka Products Limited Partnership | Apparatus, system and method for fluid delivery |
US8900188B2 (en) | 2007-12-31 | 2014-12-02 | Deka Products Limited Partnership | Split ring resonator antenna adapted for use in wirelessly controlled medical device |
EP2163243A1 (de) * | 2008-09-12 | 2010-03-17 | Biocompatibles UK Limited | Behandlung akuter Herzinfarkte mithilfe eingekapselter Zellen, welche GLP-1-Peptide oder deren Analoga kodieren und absondern |
WO2010031059A2 (en) | 2008-09-15 | 2010-03-18 | Deka Products Limited Partnership | Systems and methods for fluid delivery |
EP2251028A1 (de) * | 2009-05-12 | 2010-11-17 | Biocompatibles Uk Ltd. | Behandlung von Augenerkrankungen unter Verwendung eingekapselter Zellen, die einen antiangiogenetischen Faktor und/oder einen neuroprotektiven Faktor codieren und sekretieren |
JP5961111B2 (ja) | 2009-07-15 | 2016-08-02 | デカ・プロダクツ・リミテッド・パートナーシップ | 注入ポンプアセンブリのための装置、システム、および方法 |
EP2525848B1 (de) | 2010-01-22 | 2016-08-03 | DEKA Products Limited Partnership | System für steuerung eines drahtes aus einer formgedächtnislegierung |
US11524151B2 (en) | 2012-03-07 | 2022-12-13 | Deka Products Limited Partnership | Apparatus, system and method for fluid delivery |
CA2914977C (en) | 2013-07-03 | 2021-11-02 | Deka Products Limited Partnership | Apparatus, system and method for fluid delivery |
CA3098372A1 (en) | 2018-04-24 | 2019-10-31 | Deka Products Limited Partnership | Apparatus and system for fluid delivery |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3769066D1 (de) * | 1986-08-28 | 1991-05-08 | Sanwa Kagaku Kenkyusho Co | Hydantoin-derivate zur behandlung von komplikationen bei diabetes. |
US5624949A (en) * | 1993-12-07 | 1997-04-29 | Eli Lilly And Company | Protein kinase C inhibitors |
AU687909B2 (en) * | 1993-12-07 | 1998-03-05 | Eli Lilly And Company | Protein kinase C inhibitors |
WO1999058510A1 (en) * | 1998-05-11 | 1999-11-18 | Takeda Chemical Industries, Ltd. | Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity |
BR9911752A (pt) * | 1998-07-01 | 2001-04-03 | Takeda Chemical Industries Ltd | Agente de regulagem da função do receptor relacionado com a retinóide, derivados de oxazol, de imidazol e de tiazol, composto, processo para regular uma função de receptor relacionado com a retinóide, e, uso de um derivado |
TWI249401B (en) * | 1999-04-14 | 2006-02-21 | Takeda Chemical Industries Ltd | Agent for improving ketosis |
CN1348555A (zh) * | 1999-06-29 | 2002-05-08 | 精工电子有限公司 | 具有轮系工作控制机构的机械时计 |
US6414002B1 (en) * | 1999-09-22 | 2002-07-02 | Bristol-Myers Squibb Company | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method |
EP1088824B1 (de) * | 1999-09-30 | 2004-01-07 | Pfizer Products Inc. | Bicyclische Pyrrolylamide als Glycogenphosphorylase-Inhibitoren |
AU1269501A (en) * | 1999-11-12 | 2001-05-30 | Novo Nordisk A/S | Use of glp-1 agonists for the inhibition of beta cell degeneration |
US20020068740A1 (en) * | 1999-12-07 | 2002-06-06 | Mylari Banavara L. | Combination of aldose reductase inhibitors and antihypertensive agents for the treatment of diabetic complications |
EP1263458B1 (de) * | 2000-03-08 | 2005-11-16 | Novo Nordisk A/S | Senkung des serum cholesterols |
ATE424413T1 (de) * | 2000-06-16 | 2009-03-15 | Lilly Co Eli | Analoge des glucagon-ähnlichen peptids-1 |
US20030158090A1 (en) * | 2001-07-23 | 2003-08-21 | Ulrik Pedersen-Bjergaard | Renin-angiotensin system in diabetes mellitus |
KR20040053210A (ko) * | 2001-11-02 | 2004-06-23 | 화이자 프로덕츠 인크. | Pde9 억제제를 사용한 인슐린 저항 증후군 및 2형당뇨병의 치료 |
-
2002
- 2002-12-20 ES ES02787467T patent/ES2280596T3/es not_active Expired - Lifetime
- 2002-12-20 WO PCT/DK2002/000888 patent/WO2003059372A2/en active IP Right Grant
- 2002-12-20 EP EP07100818A patent/EP1790353A1/de not_active Ceased
- 2002-12-20 DE DE60217918T patent/DE60217918T2/de not_active Expired - Lifetime
- 2002-12-20 JP JP2003559533A patent/JP2005516968A/ja not_active Withdrawn
- 2002-12-20 AT AT02787467T patent/ATE352312T1/de not_active IP Right Cessation
- 2002-12-20 EP EP02787467A patent/EP1461070B1/de not_active Expired - Lifetime
- 2002-12-20 AU AU2002351753A patent/AU2002351753A1/en not_active Abandoned
- 2002-12-23 US US10/328,282 patent/US20030144206A1/en not_active Abandoned
-
2007
- 2007-03-22 US US11/726,690 patent/US20070167373A1/en not_active Abandoned
-
2010
- 2010-03-29 US US12/748,869 patent/US20100184690A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1461070A2 (de) | 2004-09-29 |
US20030144206A1 (en) | 2003-07-31 |
US20070167373A1 (en) | 2007-07-19 |
DE60217918T2 (de) | 2007-11-15 |
DE60217918D1 (de) | 2007-03-15 |
AU2002351753A8 (en) | 2003-07-30 |
ES2280596T3 (es) | 2007-09-16 |
US20100184690A1 (en) | 2010-07-22 |
WO2003059372A3 (en) | 2004-03-25 |
EP1461070B1 (de) | 2007-01-24 |
AU2002351753A1 (en) | 2003-07-30 |
WO2003059372A2 (en) | 2003-07-24 |
JP2005516968A (ja) | 2005-06-09 |
EP1790353A1 (de) | 2007-05-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE352312T1 (de) | Kombinierte verwendung einer glp-1-verbindung und eines aldose reduktase inhibitors | |
PT1296959E (pt) | Metodos e composicoes que utilizam quinazolinonas | |
EA200300906A1 (ru) | Новые спиротрициклические производные и их применение в качестве ингибиторов фосфодиэстеразы-7 | |
DE59910084D1 (de) | Organische Salze von Isoleucyl-Thiazolidin und -Pyrrolidin und ihre Verwendung als Dipeptidylpeptidase-Inhibitoren | |
DE60224189D1 (de) | Dipeptidylpeptidase-hemmer zur behandlung von diabetes | |
SG153851A1 (en) | N-(1-(1-benzyl -4-phenyl-1h-imidazol-2-yl)-2,2-dymethylpropyl)benzamide derivatives and related compounds as kinesin spindle protein (ksp) inhibitors for the treatment of cancer | |
WO2003024391A3 (en) | Treatment and prevention of mucositis in cancer patients | |
NO20026038D0 (no) | Kombinasjoner av dipeptidylpeptidase IV inhibitorer og andre antidiabetiskemidler for behandlingen av diabetes mellitus | |
SE0301888D0 (sv) | New use VII | |
WO2002072545A3 (en) | 9-aminoacyl tetracycline compounds and methods of use thereof | |
ATE318139T1 (de) | Dipeptidylpeptidase-hemmer zur behandlung von diabetes | |
SE0301886D0 (sv) | New use V | |
SE0301882D0 (sv) | New use I | |
WO2003030819A3 (en) | Tetracycline derivatives and methods of use thereof | |
TR200100773T2 (tr) | Bir aP2 önleyicisinin ve kombinasyonunun kullanıldığı diyabet tedavi yöntemi | |
DE60127537D1 (de) | VERWENDUNG VON 2-(4-ETHOXY-PHENYL)-3-(4-METHANESULFONYL-PHENYL)-PYRAZOLOÄ1,5-bÜPYRIDAZINE ZUR BEHANDLUNG VON NICHTULZERATIVER DYSPEPSIE | |
WO2003024386A8 (en) | Use of potent, selective and non toxic c-kit inhibitors for treating interstitial cystitis | |
MXPA02012713A (es) | Combinacion de inhibidores de fructosabisfosfatasas y agentes antidiabeticos, util para el tratamiento de la diabetes. | |
NO20071098L (no) | Quinazolinderivater som er nyttige ved behandling av perifer arteriesykdom og som fosfodiesterase-inhibitorer | |
WO2006002763A3 (de) | Substituierte tetrahydroisochinoline als mmp-inhibitoren, verfahren zu ihrer herstellung und ihre verwendung als medikament | |
PT1378246E (pt) | Inibidores da spla2 para a arteriosclerose | |
HUP9801022A2 (hu) | Eljárás aldóz reduktáz inhibítor alkalmazása diabetikus szívizom-betegség megelőzésére vagy megfordítására | |
ATE297902T1 (de) | Sulfonyl-pyridazinon-derivate zur verwendung als aldose-reduktase-inhibitoren | |
WO2001087281A3 (en) | Method for enhancing cognitive function | |
ECSP034684A (es) | Uso de 2-amino-1-(4-hidroxi-2-metanosulfonamidofenil)etanol para tratar la incontinencia urinaria |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |