ATE346914T1 - Udp-n-acetylglucosamin: galaktose-beta 1,3-n- acetylgalaktosamin-alpha-r/(glcnac -galnac) beta 1,6-n-acetylglucosaminyltransferase, c2gnt3 - Google Patents

Udp-n-acetylglucosamin: galaktose-beta 1,3-n- acetylgalaktosamin-alpha-r/(glcnac -galnac) beta 1,6-n-acetylglucosaminyltransferase, c2gnt3

Info

Publication number
ATE346914T1
ATE346914T1 AT00954402T AT00954402T ATE346914T1 AT E346914 T1 ATE346914 T1 AT E346914T1 AT 00954402 T AT00954402 T AT 00954402T AT 00954402 T AT00954402 T AT 00954402T AT E346914 T1 ATE346914 T1 AT E346914T1
Authority
AT
Austria
Prior art keywords
c2gnt3
disclosed
dna
methods
beta
Prior art date
Application number
AT00954402T
Other languages
English (en)
Inventor
Tilo Schwientek
Henrik Clausen
Original Assignee
Glycozym Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycozym Aps filed Critical Glycozym Aps
Application granted granted Critical
Publication of ATE346914T1 publication Critical patent/ATE346914T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • AIDS & HIV (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT00954402T 1999-08-24 2000-08-24 Udp-n-acetylglucosamin: galaktose-beta 1,3-n- acetylgalaktosamin-alpha-r/(glcnac -galnac) beta 1,6-n-acetylglucosaminyltransferase, c2gnt3 ATE346914T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15048899P 1999-08-24 1999-08-24

Publications (1)

Publication Number Publication Date
ATE346914T1 true ATE346914T1 (de) 2006-12-15

Family

ID=22534762

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00954402T ATE346914T1 (de) 1999-08-24 2000-08-24 Udp-n-acetylglucosamin: galaktose-beta 1,3-n- acetylgalaktosamin-alpha-r/(glcnac -galnac) beta 1,6-n-acetylglucosaminyltransferase, c2gnt3

Country Status (11)

Country Link
US (5) US6635461B1 (de)
EP (1) EP1206529B1 (de)
JP (1) JP4642301B2 (de)
AT (1) ATE346914T1 (de)
AU (1) AU775990B2 (de)
CA (1) CA2384978C (de)
DE (1) DE60032150T2 (de)
MX (1) MXPA02001977A (de)
NO (1) NO20020813L (de)
NZ (1) NZ517219A (de)
WO (1) WO2001014535A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6593119B2 (en) 2000-02-29 2003-07-15 Glycodesign, Inc. Core 2 β-1,6-N-acetylglycosaminyltransferase gene
JP4300267B2 (ja) * 2001-12-28 2009-07-22 独立行政法人産業技術総合研究所 新規ｎ−アセチルグルコサミン転移酵素及びそれをコードする核酸
GB0329667D0 (en) * 2003-12-22 2004-01-28 King S College London Core 2 GlcNAc-T inhibitor
GB0513881D0 (en) * 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors III
US20080182801A1 (en) * 2003-12-22 2008-07-31 Btg International Limited Core 2 glcnac-t inhibitors
US20060216273A1 (en) * 2005-03-25 2006-09-28 Min-Chuan Huang Gene therapy for colorectal cancer
GB0512726D0 (en) * 2005-06-22 2005-07-27 Btg Int Ltd Multiple sclerosis therapy and diagnosis
GB0513883D0 (en) * 2005-07-06 2005-08-10 Btg Int Ltd Diagnosis of Atherosclerosis
GB0513888D0 (en) * 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors II
JP2009511082A (ja) * 2005-10-17 2009-03-19 ヘルス リサーチ インコーポレイテッド 糖類のためのトランスフェラーゼに特異的な受容体並びにその入手及び使用方法
WO2013015363A1 (ja) * 2011-07-26 2013-01-31 独立行政法人産業技術総合研究所 上皮性卵巣癌マーカー検出用抗体及び上皮性卵巣癌判定方法
US9726668B2 (en) 2012-02-09 2017-08-08 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
US10303846B2 (en) 2014-08-14 2019-05-28 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
EP3423590A4 (de) 2016-03-03 2020-02-26 Memed Diagnostics Ltd. Rna-determinanten zur unterscheidung zwischen bakteriellen und viralen infektionen
IL287757B (en) * 2016-03-03 2022-07-01 Memed Diagnostics Ltd An RNA test to diagnose the type of infection
CA3027341A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
US11340223B2 (en) 2016-07-10 2022-05-24 Memed Diagnostics Ltd. Early diagnosis of infections
US11385241B2 (en) 2016-09-29 2022-07-12 Memed Diagnostics Ltd. Methods of prognosis and treatment
WO2018060999A1 (en) 2016-09-29 2018-04-05 Memed Diagnostics Ltd. Methods of risk assessment and disease classification
CN108192978B (zh) * 2018-03-29 2020-10-27 青岛泱深生物医药有限公司 一种肿瘤相关生物标志物及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60234574A (ja) * 1984-05-08 1985-11-21 日本たばこ産業株式会社 シガレツト製造機における中味たばこ量制御装置
AU4751990A (en) 1988-12-13 1990-07-10 La Jolla Cancer Research Foundation Nucleotides encoding human b1, 4-galactosyltransferase and uses thereof
US5360733A (en) 1992-10-01 1994-11-01 La Jolla Cancer Research Foundation Human β1-6 n-acetylglucosaminyl transferase
WO1995007020A1 (en) * 1993-09-09 1995-03-16 La Jolla Cancer Research Foundation EXPRESSION OF THE DEVELOPMENTAL I ANTIGEN BY A CLONED HUMAN cDNA ENCODING A BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE
US5484590A (en) * 1993-09-09 1996-01-16 La Jolla Cancer Research Foundation Expression of the developmental I antigen by a cloned human cDNA encoding a member of a β-1,6-N-acetylglucosaminyltransferase gene family
US6136580A (en) 1999-01-19 2000-10-24 The Burnham Institute β-1-6-N-acetylglucosaminyltransferase that forms core 2, core 4 and I branches
US6593119B2 (en) * 2000-02-29 2003-07-15 Glycodesign, Inc. Core 2 β-1,6-N-acetylglycosaminyltransferase gene

Also Published As

Publication number Publication date
DE60032150T2 (de) 2007-09-27
US7078206B2 (en) 2006-07-18
JP4642301B2 (ja) 2011-03-02
US7094887B2 (en) 2006-08-22
MXPA02001977A (es) 2002-09-18
EP1206529A2 (de) 2002-05-22
NZ517219A (en) 2004-06-25
US6794169B2 (en) 2004-09-21
NO20020813L (no) 2002-04-19
JP2003507061A (ja) 2003-02-25
US6635461B1 (en) 2003-10-21
US20040203092A1 (en) 2004-10-14
AU775990B2 (en) 2004-08-19
AU6686800A (en) 2001-03-19
CA2384978C (en) 2012-10-23
US20030054525A1 (en) 2003-03-20
US7097994B2 (en) 2006-08-29
EP1206529B1 (de) 2006-11-29
WO2001014535A3 (en) 2001-06-21
NO20020813D0 (no) 2002-02-19
US20040203111A1 (en) 2004-10-14
WO2001014535A2 (en) 2001-03-01
US20030180778A1 (en) 2003-09-25
CA2384978A1 (en) 2001-03-01
DE60032150D1 (de) 2007-01-11

Similar Documents

Publication Publication Date Title
ATE346914T1 (de) Udp-n-acetylglucosamin: galaktose-beta 1,3-n- acetylgalaktosamin-alpha-r/(glcnac -galnac) beta 1,6-n-acetylglucosaminyltransferase, c2gnt3
EP1129179A4 (de) UDP-Galaktose: BETA-I(N)-Acetyl-Glukosamin BETA1,3 Galaktosyltransferasen, BETA3Gal-T5
Kytzia et al. Evidence for two different active sites on human beta-hexosaminidase A. Interaction of GM2 activator protein with beta-hexosaminidase A.
Herscovics Processing glycosidases of Saccharomyces cerevisiae
Viladot et al. Probing the mechanism of Bacillus 1, 3-1, 4-β-D-glucan 4-glucanohydrolases by chemical rescue of inactive mutants at catalytically essential residues
Telkov et al. Proteins of the Rpf (resuscitation promoting factor) family are peptidoglycan hydrolases
Finnis et al. Thymidine phosphorylase activity of platelet‐derived endothelial cell growth factor is responsible for endothelial cell mitogenicity
DK0470145T3 (da) Kartoffel-alfa-amylasegen
ATE302853T1 (de) Pflanzliche (gnti)-sequenzen und verwendung derselben zur gewinnung von pflanzen mit verminderter oder fehlender n- acetylglucosaminyltransferase i (gnti)-aktivität
NO20021931L (no) L-pantolacton-hydrolase og en fremgangsmåte for fremstilling av D-pantolacton
Horsburgh et al. LytG of Bacillus subtilis is a novel peptidoglycan hydrolase: the major active glucosaminidase
Bakke et al. Identification, characterization, and molecular cloning of a novel hyaluronidase, a member of glycosyl hydrolase family 16, from Penicillium spp.
Hartl et al. Second naturally occurring β-galactosidase in E. coli
TWI245800B (en) Endo-beta-N-acetylglucosaminidase gene
Chen et al. A tetrad of ionizable amino acids is important for catalysis in barley β-glucanases
Filipowicz et al. Cyclization of RNA 3'-terminal phosphate by cyclase from HeLa cells proceeds via formation of N (3') pp (5') A activated intermediate.
JP2005516594A (ja) 可溶性ＧｌｃＮＡｃホスフォトランスフェラーゼ
WO2003102194A1 (fr) Chondroitine synthetase et codage de l'adn pour l'enzyme
Belaz et al. Identification, biochemical characterization, and in-vivo expression of the intracellular invertase BfrA from the pathogenic parasite Leishmania major
Oshima et al. Isolation and sequence of a novel amphibian pancreatic chitinase
Sakakibara et al. Construction and expression of human aldolase A and B expression plasmids in Escherichia coli host
Suresh et al. Evidence that the putative α-glucosidase of Thermotoga maritima MSB8 is a pNP α-D-glucuronopyranoside hydrolyzing α-glucuronidase
US20030129723A1 (en) Thermophilic endoglucanase
ATE346913T1 (de) Udp-n-acetyl glucosamin: galaktose-batel, 3-n- acetyl galaktosamin-alpha-r/ n-acetyl glucosamin- betal, 3-n-acetyl galaktosamin-alpha-r (glcnac to galnac) betal, 6-n-acetyl glucosaminyl transferase, c2/4gnt
Nakaya et al. Changes of DNA ligase in developing rat brain

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties