ATE343597T1 - Diagnostisches assay für typ-2-heparin induzierte thrombocytopenie - Google Patents
Diagnostisches assay für typ-2-heparin induzierte thrombocytopenieInfo
- Publication number
- ATE343597T1 ATE343597T1 AT00961409T AT00961409T ATE343597T1 AT E343597 T1 ATE343597 T1 AT E343597T1 AT 00961409 T AT00961409 T AT 00961409T AT 00961409 T AT00961409 T AT 00961409T AT E343597 T1 ATE343597 T1 AT E343597T1
- Authority
- AT
- Austria
- Prior art keywords
- type
- induced thrombocytopenia
- diagnostic assay
- heparin induced
- heparin
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
- G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/22—Haematology
- G01N2800/222—Platelet disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15131499P | 1999-08-30 | 1999-08-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE343597T1 true ATE343597T1 (de) | 2006-11-15 |
Family
ID=22538197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00961409T ATE343597T1 (de) | 1999-08-30 | 2000-08-29 | Diagnostisches assay für typ-2-heparin induzierte thrombocytopenie |
Country Status (7)
Country | Link |
---|---|
US (1) | US7011953B2 (de) |
EP (1) | EP1254181B1 (de) |
AT (1) | ATE343597T1 (de) |
AU (1) | AU7336400A (de) |
CA (1) | CA2401411A1 (de) |
DE (1) | DE60031576D1 (de) |
WO (1) | WO2001016184A2 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7732213B2 (en) * | 1999-02-22 | 2010-06-08 | Coramed Healthcare, Inc. | Method of evaluating patient hemostasis |
US7179652B2 (en) * | 1999-02-22 | 2007-02-20 | Haemoscope Corporation | Protocol for monitoring platelet inhibition |
US8008086B2 (en) * | 1999-02-22 | 2011-08-30 | Cora Healthcare, Inc. | Protocol for monitoring direct thrombin inhibition |
US7655411B2 (en) * | 2002-08-23 | 2010-02-02 | W2 Holdings, Inc. | Thrombospondin fragments and binding agents in the detection, diagnosis and evaluation of cancer |
US7524670B2 (en) * | 2003-08-05 | 2009-04-28 | Haemoscope Corporation | Protocol and apparatus for determining heparin-induced thrombocytopenia |
US20060074049A1 (en) * | 2004-10-05 | 2006-04-06 | Mitchell Krathwohl | Use of heparinoids for treatment and prevention of dementia |
FR2902884B1 (fr) * | 2006-06-23 | 2008-12-26 | Hyphen Biomed Soc Par Actions | Procede pour la detection des anticorps heparine-dependants et le diagnostic des pathologies immunes ou auto-immnues potentialisees par l'heparine telle que la thrombopenie induite par l'heparine |
US8940495B2 (en) | 2008-02-29 | 2015-01-27 | BioMedomics, Inc | Rapid and sensitive method for quantitative determination of the level of heparin—PF4 complex induced immunoglobulin antibodies |
ES2561984T3 (es) * | 2008-08-27 | 2016-03-01 | Lsi Medience Corporation | Anticuerpo anticomplejo heparina/FP4 modificado y patrón de anticuerpo TIH |
WO2013042111A2 (en) * | 2011-01-20 | 2013-03-28 | Aaron Tomer | Platelet analysis system |
US9599623B2 (en) | 2011-06-09 | 2017-03-21 | Immucor Gti Diagnostics, Inc. | Diagnostic devices, methods and systems for detecting platelet factor 4 (PF4)/heparin antibodies |
EP2828658B1 (de) * | 2012-03-23 | 2017-06-14 | The Trustees Of The University Of Pennsylvania | Verfahren zur identifikation von hit-antikörpern und pf4-antikörpern sowie zelllinien zur verwendung darin |
WO2013165969A2 (en) * | 2012-05-01 | 2013-11-07 | The Trustees Of The University Of Pennsylvania | Methods and kits for diagnosing heparin-induced thrombocytopenia |
ES2924187T3 (es) * | 2017-03-29 | 2022-10-05 | Emosis | Un ensayo funcional de trombocitopenia inducida por heparina, rápido y bajo demanda |
CN108956998A (zh) * | 2018-04-11 | 2018-12-07 | 中翰盛泰生物技术股份有限公司 | 一种应用免疫荧光干式定量法的肝素结合蛋白测定试剂盒及测定方法 |
CN112255416A (zh) * | 2020-09-29 | 2021-01-22 | 北京利德曼生化股份有限公司 | 使用磁微粒化学发光定量检测hbp的试剂盒及其制备、检测方法 |
CN115490766A (zh) * | 2022-09-16 | 2022-12-20 | 山东大学 | 一种人pf4的特征多肽及其应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
US4444879A (en) * | 1981-01-29 | 1984-04-24 | Science Research Center, Inc. | Immunoassay with article having support film and immunological counterpart of analyte |
US5466582A (en) * | 1990-08-09 | 1995-11-14 | Serbio | Thrombocytopenia determination |
US5585243A (en) | 1993-09-15 | 1996-12-17 | The Blood Center Of Southeastern Wisconsin, Inc. | Method of detecting cytopenia that is mediated by drug-dependent antibody binding to blood cells |
US5763201A (en) * | 1996-02-05 | 1998-06-09 | Emory University | Flow cytometry assay for heparin-induced thrombocytopenia |
US5972718A (en) * | 1996-02-28 | 1999-10-26 | The Blood Center Research Foundation | Method of detecting heparin-induced thrombocytopenia |
WO2000002587A1 (en) * | 1998-07-13 | 2000-01-20 | Board Of Regents, The University Of Texas System | Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids |
-
2000
- 2000-08-29 WO PCT/US2000/023707 patent/WO2001016184A2/en active IP Right Grant
- 2000-08-29 EP EP00961409A patent/EP1254181B1/de not_active Expired - Lifetime
- 2000-08-29 AT AT00961409T patent/ATE343597T1/de not_active IP Right Cessation
- 2000-08-29 AU AU73364/00A patent/AU7336400A/en not_active Abandoned
- 2000-08-29 DE DE60031576T patent/DE60031576D1/de not_active Expired - Lifetime
- 2000-08-29 CA CA002401411A patent/CA2401411A1/en not_active Abandoned
-
2002
- 2002-02-27 US US10/084,832 patent/US7011953B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2001016184A3 (en) | 2001-06-21 |
AU7336400A (en) | 2001-03-26 |
EP1254181A2 (de) | 2002-11-06 |
WO2001016184A2 (en) | 2001-03-08 |
DE60031576D1 (en) | 2006-12-07 |
US20020197697A1 (en) | 2002-12-26 |
EP1254181B1 (de) | 2006-10-25 |
US7011953B2 (en) | 2006-03-14 |
CA2401411A1 (en) | 2001-03-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |