ATE338139T1 - Herstellung von 3-hydroxypropionsäure in rekombinanten organismen - Google Patents

Herstellung von 3-hydroxypropionsäure in rekombinanten organismen

Info

Publication number
ATE338139T1
ATE338139T1 AT00959652T AT00959652T ATE338139T1 AT E338139 T1 ATE338139 T1 AT E338139T1 AT 00959652 T AT00959652 T AT 00959652T AT 00959652 T AT00959652 T AT 00959652T AT E338139 T1 ATE338139 T1 AT E338139T1
Authority
AT
Austria
Prior art keywords
production
hydroxypropionic acid
recombinant organisms
bacterial host
glycerol
Prior art date
Application number
AT00959652T
Other languages
English (en)
Inventor
Patrick F Suthers
Douglas C Cameron
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Application granted granted Critical
Publication of ATE338139T1 publication Critical patent/ATE338139T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/0103—Glycerol dehydratase (4.2.1.30)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT00959652T 1999-08-30 2000-08-30 Herstellung von 3-hydroxypropionsäure in rekombinanten organismen ATE338139T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15144099P 1999-08-30 1999-08-30

Publications (1)

Publication Number Publication Date
ATE338139T1 true ATE338139T1 (de) 2006-09-15

Family

ID=22538777

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00959652T ATE338139T1 (de) 1999-08-30 2000-08-30 Herstellung von 3-hydroxypropionsäure in rekombinanten organismen

Country Status (6)

Country Link
EP (1) EP1124979B1 (de)
AT (1) ATE338139T1 (de)
AU (1) AU7093600A (de)
BR (1) BR0008355A (de)
DE (1) DE60030403D1 (de)
WO (1) WO2001016346A1 (de)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2429039A1 (en) 2000-11-20 2002-05-30 Cargill, Incorporated 3-hydroxypropionic acid and other organic compounds
EP1575881B1 (de) 2002-01-18 2009-05-27 Novozymes A/S Alanin-2,3-aminomutase
EP1432724A4 (de) * 2002-02-20 2006-02-01 Sirna Therapeutics Inc Durch rna-interferenz vermittelte inhibierung von map-kinase-genen
EP1483388B1 (de) * 2002-03-13 2008-11-05 Evonik Degussa GmbH Verfahren zur herstellung von l-aminosäuren unter verwendung von stämmen der familie enterobacteriaceae
DE10210960A1 (de) * 2002-03-13 2003-09-25 Degussa Verfahren zur fermentativen Hestellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
CN100577628C (zh) * 2002-03-25 2010-01-06 嘉吉有限公司 制造β-羟基羧酸衍生物的方法
DK1706457T3 (da) 2003-12-04 2012-05-21 Novozymes As Fremstilling af 3-hydroxypropionsyre ved anvendelse af beta-alanin/pyruvataminotransferase
JP2008507970A (ja) 2004-07-30 2008-03-21 カーギル インコーポレイテッド アラニン２，３アミノムターゼ
CN101068923A (zh) 2004-10-25 2007-11-07 科德克希思公司 改良的丙氨酸2,3－氨基变位酶和相关多核苷酸
TWI529181B (zh) * 2005-02-28 2016-04-11 贏創德固賽有限責任公司 以可更新原料為基之吸水聚合物結構及其生產的方法
JP2007082476A (ja) * 2005-09-22 2007-04-05 Nippon Shokubai Co Ltd グリセリンから３−ヒドロキシプロピオン酸を製造する方法
DE102005048818A1 (de) 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
WO2007047773A2 (en) 2005-10-14 2007-04-26 Codexis, Inc. Alanine 2,3-aminomutases and related polynucleotides
DE102006039203B4 (de) 2006-08-22 2014-06-18 Evonik Degussa Gmbh Verfahren zur Herstellung von durch Kristallisation gereinigter Acrylsäure aus Hydroxypropionsäure sowie Vorrichtung dazu
DE102007015583A1 (de) 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
US7803589B2 (en) 2008-01-22 2010-09-28 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
CA3081506A1 (en) 2008-03-05 2009-09-11 Genomatica, Inc. Long chain alcohol-producing organisms
JP2011519561A (ja) 2008-05-01 2011-07-14 ジェノマティカ， インコーポレイテッド メタクリル酸の産生のための微生物
KR101204125B1 (ko) 2008-07-30 2012-11-22 미쓰이 가가쿠 가부시키가이샤 폴리에스터 폴리올, 폴리우레탄용 조성물, 폴리우레탄 폼용 조성물, 폴리우레탄 수지 및 폴리우레탄 폼
EP3686272A1 (de) 2009-04-30 2020-07-29 Genomatica, Inc. Organismen zur herstellung von 1,3-butandiol
US8993285B2 (en) 2009-04-30 2015-03-31 Genomatica, Inc. Organisms for the production of isopropanol, n-butanol, and isobutanol
WO2010131604A1 (ja) 2009-05-15 2010-11-18 株式会社日本触媒 (メタ)アクリル酸の製造方法
US8637701B2 (en) 2009-05-15 2014-01-28 Nippon Shokubai Co., Ltd. Method for producing (meth) acrylic acid
CN102414160B (zh) 2009-05-15 2014-06-04 株式会社日本触媒 制备(甲基)丙烯酸的方法和结晶***
DK2462221T3 (en) 2009-08-05 2017-05-22 Genomatica Inc SEMISYNTHETIC TEREPHTHALIC ACID BY MICRO-ORGANISMS PRODUCING MUCONIC ACID
CA2775390C (en) 2009-09-27 2021-06-29 Opx Biotechnologies, Inc. Method for producing 3-hydroxypropionic acid and other products
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
EP2491125A4 (de) 2009-10-23 2014-04-23 Genomatica Inc Mikroorganismen zur herstellung von anilin
EP2495328B1 (de) * 2009-10-29 2016-03-30 Korea Research Institute of Bioscience and Biotechnology Neues verfahren zur herstellung von 3-hydroxypropionsäure aus glycerin
KR20120123742A (ko) 2010-01-29 2012-11-09 게노마티카 인코포레이티드 Ｐ-톨루에이트 및 테레프탈레이트 생합성 미생물 및 생합성 방법
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
WO2012001003A1 (en) 2010-07-02 2012-01-05 Metabolic Explorer Method for the preparation of hydroxy acids
EP3312284A3 (de) 2010-07-26 2018-05-30 Genomatica, Inc. Mikroorganismen und verfahren zur biosynthese von aromaten, 2,4-pentadienoat und 1,3-butadien
WO2012019175A2 (en) 2010-08-06 2012-02-09 Mascoma Corporation Production of malonyl-coa drived products via anaerobic pathways
CN107828671B (zh) 2010-11-22 2022-03-08 卡吉尔公司 用于生产3-羟基丙酸的组合物和方法
US9029596B2 (en) 2010-12-28 2015-05-12 Nippon Shokubai Co., Ltd. Methods for producing acrylic acid and/or ester thereof and polymer of the acrylic acid and/or ester thereof
EP2751261B1 (de) 2011-09-30 2018-08-29 Novozymes, Inc. Dehydrogenasevarianten und dafür kodierende polynukleotide
KR101494386B1 (ko) * 2011-12-07 2015-02-23 삼성전자주식회사 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산을 생산하는 재조합 미생물 및 이를 이용한 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산의 생산방법
WO2013085321A1 (ko) * 2011-12-07 2013-06-13 삼성전자주식회사 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산을 생산하는 재조합 미생물 및 이를 이용한 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산의 생산방법
US9522867B2 (en) 2012-06-27 2016-12-20 Nippon Shokubai Co., Ltd. (meth)acrylic acid production method, and, hydrophilic resin production method
WO2014026162A1 (en) 2012-08-10 2014-02-13 Opx Biotechnologies, Inc. Microorganisms and methods for the production of fatty acids and fatty acid derived products
BR112015012409A2 (pt) 2012-11-30 2017-09-12 Novozymes Inc célula recombinante de levedura, e, método de produção de 3-hp
BR112015015585B1 (pt) * 2013-01-08 2020-11-17 Shell Internationale Research Maatschappij B.V. processo para produzir ácido acrílico
US9512057B2 (en) 2013-03-15 2016-12-06 Cargill, Incorporated 3-hydroxypropionic acid compositions
US10047383B2 (en) 2013-03-15 2018-08-14 Cargill, Incorporated Bioproduction of chemicals
EP3008179A1 (de) 2013-06-14 2016-04-20 Technical University of Denmark 3hp-toleranz
EP3022310B1 (de) 2013-07-19 2019-10-16 Cargill, Incorporated Mikroorganismen und verfahren zur herstellung von fettsäuren und aus fettsäuren gewonnenen produkten
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US9938224B2 (en) 2013-10-17 2018-04-10 Cargill, Incorporated Methods for producing alkyl hydroxyalkanoates
EP2993228B1 (de) 2014-09-02 2019-10-09 Cargill, Incorporated Herstellung von fettsäureestern
US10239819B2 (en) 2014-10-17 2019-03-26 Cargill, Incorporated Methods for producing an ester of an alpha, beta-unsaturated carboxylic acid
EP3262161B1 (de) 2015-02-27 2021-06-30 Novozymes A/S Mutante wirtszellen zur herstellung von 3-hydroxypropionsäure
US20200262778A1 (en) 2016-09-27 2020-08-20 Shell Oil Company Process for production of allyl alcohol
CN110494566A (zh) 2017-02-02 2019-11-22 嘉吉公司 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞
AU2019209324A1 (en) * 2018-01-16 2020-07-09 Dicerna Pharmaceuticals, Inc. Compositions and methods for inhibiting ALDH2 expression
EP4190907A4 (de) * 2020-07-31 2023-12-06 LG Chem, Ltd. Verfahren zur herstellung von 3-hydroxypropionsäure durch zwei stufen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100509310B1 (ko) * 1996-11-13 2005-08-22 이 아이 듀폰 디 네모아 앤드 캄파니 재조합 유기체에 의한 1,3-프로판디올의 생산 방법
ATE385521T1 (de) * 1998-08-04 2008-02-15 Metabolix Inc Herstellung von polyhydroxyalkanoaten aus polyolen

Also Published As

Publication number Publication date
EP1124979A1 (de) 2001-08-22
EP1124979A4 (de) 2002-08-28
AU7093600A (en) 2001-03-26
EP1124979B1 (de) 2006-08-30
BR0008355A (pt) 2002-07-16
DE60030403D1 (de) 2006-10-12
WO2001016346A1 (en) 2001-03-08

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