ATE333323T1 - Verfahren und vorrichtung zur trennung von partikeln in einer flüssigkeitsströmung - Google Patents

Verfahren und vorrichtung zur trennung von partikeln in einer flüssigkeitsströmung

Info

Publication number
ATE333323T1
ATE333323T1 AT04721159T AT04721159T ATE333323T1 AT E333323 T1 ATE333323 T1 AT E333323T1 AT 04721159 T AT04721159 T AT 04721159T AT 04721159 T AT04721159 T AT 04721159T AT E333323 T1 ATE333323 T1 AT E333323T1
Authority
AT
Austria
Prior art keywords
particles
liquid
liquid flow
compartment
deflection
Prior art date
Application number
AT04721159T
Other languages
English (en)
Inventor
Torsten Mueller
Thomas Schnelle
Rolf Hagedorn
Original Assignee
Evotec Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evotec Ag filed Critical Evotec Ag
Application granted granted Critical
Publication of ATE333323T1 publication Critical patent/ATE333323T1/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00Separating dispersed particles from liquids by electrostatic effect
    • B03C5/005Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Electrostatic Separation (AREA)
  • Cyclones (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
AT04721159T 2003-03-17 2004-03-17 Verfahren und vorrichtung zur trennung von partikeln in einer flüssigkeitsströmung ATE333323T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10311716A DE10311716A1 (de) 2003-03-17 2003-03-17 Verfahren und Vorrichtung zur Trennung von Partikeln in einer Flüssigkeitsströmung

Publications (1)

Publication Number Publication Date
ATE333323T1 true ATE333323T1 (de) 2006-08-15

Family

ID=32980607

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04721159T ATE333323T1 (de) 2003-03-17 2004-03-17 Verfahren und vorrichtung zur trennung von partikeln in einer flüssigkeitsströmung

Country Status (5)

Country Link
US (2) US8262883B2 (de)
EP (1) EP1603678B1 (de)
AT (1) ATE333323T1 (de)
DE (2) DE10311716A1 (de)
WO (1) WO2004082840A1 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004100175A1 (en) 2003-05-08 2004-11-18 The University Court Of The University Of St Andrews Fractionation of particles
US7704362B2 (en) * 2005-03-04 2010-04-27 Wisconsin Alumni Research Foundation Apparatus for transport and analysis of particles using dielectrophoresis
DE102005012128A1 (de) * 2005-03-16 2006-09-21 Evotec Technologies Gmbh Mikrofluidisches System und zugehöriges Ansteuerverfahren
DE102005046657B4 (de) * 2005-09-29 2008-10-09 Bruker Daltonik Gmbh Stationäres Trennsystem für Gemischkomponenten
US20070105206A1 (en) * 2005-10-19 2007-05-10 Chang Lu Fluidic device
CN100457239C (zh) * 2005-12-30 2009-02-04 财团法人工业技术研究院 多样品微流体介电泳分离装置
GB0618605D0 (en) * 2006-09-21 2006-11-01 Univ St Andrews Optical sorting
GB0618606D0 (en) 2006-09-21 2006-11-01 Univ St Andrews Optical sorting
DE102006052925A1 (de) * 2006-11-09 2008-05-15 Evotec Technologies Gmbh Feldkäfig und zugehöriges Betriebsverfahren
US7935906B2 (en) * 2007-04-17 2011-05-03 Dynamic Connections, Llc Separation and manipulation of a chiral object
US8698031B2 (en) * 2007-04-17 2014-04-15 Dynamic Connections, Llc Separation and manipulation of a chiral object
US20090050482A1 (en) * 2007-08-20 2009-02-26 Olympus Corporation Cell separation device and cell separation method
US8740600B1 (en) * 2007-10-09 2014-06-03 Isopur Technologies, Inc. Apparatus for agglomerating particles in a non-conductive liquid
KR101338349B1 (ko) * 2007-11-30 2013-12-06 연세대학교 산학협력단 미세입자 분리 장치 및 이의 제작 방법
ES2699679T3 (es) 2008-04-03 2019-02-12 Univ California Sistema multidimensional ex-vivo para la separación y el aislamiento de células, vesículas, nanopartículas y biomarcadores
KR101023040B1 (ko) * 2008-11-13 2011-03-24 한국항공대학교산학협력단 고속 입자분리 장치 및 그 방법
DE102011050254A1 (de) * 2011-05-10 2012-11-15 Technische Universität Dortmund Verfahren zur Separation polarisierbarer Biopartikel
JP2014531199A (ja) * 2011-08-19 2014-11-27 ウー アラン ヤンWU, Allan, Yang 並行光線療法を伴う傾斜アレイ誘電泳動分離(GrADS)
SG11201400151RA (en) * 2011-09-07 2014-07-30 Panasonic Healthcare Co Ltd Microorganism quantity measurement cell and microorganism quantity measurement device comprising same
JP5924276B2 (ja) * 2012-04-03 2016-05-25 ソニー株式会社 流路デバイス、粒子分取装置及び粒子分取方法
US8932815B2 (en) 2012-04-16 2015-01-13 Biological Dynamics, Inc. Nucleic acid sample preparation
US8603791B2 (en) 2012-04-16 2013-12-10 Biological Dynamics, Inc. Nucleic acid sample preparation
US9192944B2 (en) * 2012-09-30 2015-11-24 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University Methods, systems and apparatus for size-based particle separation
US9731293B2 (en) * 2012-10-03 2017-08-15 The United States Of America, As Represented By The Secretary Of The Navy Paired laser and electrokinetic separation, manipulation, and analysis device
EP2980558B1 (de) * 2013-03-26 2019-11-06 Sony Corporation Messvorrichtung und messverfahren
KR101501983B1 (ko) * 2013-06-05 2015-03-13 한국항공대학교산학협력단 음의 유전 영동력 기반의 고효율 다단 세포 분리장치
EP3049531B8 (de) * 2013-09-24 2019-08-14 AIT Austrian Institute of Technology GmbH Verfahren zur pathogendiagnose mittels eines elektrischen feldes
AU2015222978B2 (en) 2014-02-26 2021-05-13 Beth Israel Deaconess Medical Center System and method for cell levitation and monitoring
US20150273231A1 (en) * 2014-03-31 2015-10-01 Electronics And Telecommunications Research Institute Plasma system
CN106459966A (zh) 2014-04-08 2017-02-22 生物动力学公司 用于生物材料的分离的改进的装置
US10657869B2 (en) 2014-09-10 2020-05-19 E Ink Corporation Methods for driving color electrophoretic displays
KR102061435B1 (ko) 2014-09-10 2019-12-31 이 잉크 코포레이션 착색 전기영동 디스플레이들
EP3291916B1 (de) * 2015-05-04 2020-09-09 Biological Dynamics, Inc. Partikelbasierter immunoassay mit wechselstromelektrokinetik
US10232369B2 (en) 2016-03-24 2019-03-19 Biological Dynamics, Inc. Disposable fluidic cartridge and components
CN106323727B (zh) * 2016-11-21 2023-07-14 大连海事大学 一种基于微通道内液体拉力效应的颗粒分离装置及方法
US10629833B2 (en) * 2016-11-21 2020-04-21 Northwestern University Flashing ratchets
US10596567B2 (en) * 2017-03-27 2020-03-24 International Business Machines Corporation Microfluidic ratchets for displacing particles
WO2018208820A1 (en) 2017-05-08 2018-11-15 Biological Dynamics, Inc. Methods and systems for analyte information processing
CN107442285B (zh) * 2017-07-27 2023-03-24 重庆科技学院 静电式滤清装置
CN107262288B (zh) * 2017-07-27 2023-03-21 重庆科技学院 带有金属颗粒的静电式净化装置
AU2018388641B2 (en) 2017-12-19 2023-09-07 Biological Dynamics, Inc. Methods and devices for detection of multiple analytes from a biological sample
CN117065932A (zh) 2018-04-02 2023-11-17 生物动力学公司 介电材料
EP3842147A1 (de) * 2019-12-27 2021-06-30 Imec VZW Feld-array-freifliessfraktionierung
US11454583B2 (en) 2019-12-27 2022-09-27 Imec Vzw Field-array free flow fractionation
EP4214574A1 (de) 2020-09-15 2023-07-26 E Ink Corporation Elektrophoretisches vierpartikelmedium mit schneller kontrastreicher optischer zustandsumschaltung
CN116113873A (zh) 2020-09-15 2023-05-12 伊英克公司 用于先进彩色电泳显示器的改进驱动电压和具有改进驱动电压的显示器
US11846863B2 (en) 2020-09-15 2023-12-19 E Ink Corporation Coordinated top electrode—drive electrode voltages for switching optical state of electrophoretic displays using positive and negative voltages of different magnitudes

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE339122B (de) * 1968-05-10 1971-09-27 Lkb Produkter Ab
DE4143573C2 (de) * 1991-08-19 1996-07-04 Fraunhofer Ges Forschung Vorrichtung zur Trennung von Gemischen mikroskopisch kleiner, in einer Flüssigkeit oder einem Gel suspendierter, dielektrischer Teilchen
DE19500683B4 (de) * 1994-12-10 2007-03-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Trapping von Molekülen und Mikropartikeln in Feldkäfigen
DE19540683A1 (de) 1995-11-01 1997-05-07 Behr Gmbh & Co Wärmeüberträger zum Kühlen von Abgas
US5993630A (en) * 1996-01-31 1999-11-30 Board Of Regents The University Of Texas System Method and apparatus for fractionation using conventional dielectrophoresis and field flow fractionation
AU4113297A (en) 1996-09-04 1998-03-26 Technical University Of Denmark A micro flow system for particle separation and analysis
US6749736B1 (en) 1998-06-26 2004-06-15 Evotec Technologies Gmbh Electrode arrangement for the dielectrophoretic diversion of particles
JP2000061472A (ja) * 1998-08-18 2000-02-29 Kurita Water Ind Ltd 水中微粒子の除去方法および装置
DE19859459A1 (de) 1998-12-22 2000-06-29 Evotec Biosystems Ag Mikrosysteme zur Zellpermeation und Zellfusion
WO2000073780A1 (en) * 1999-05-28 2000-12-07 Proteologics, Inc. Methods and apparatus for nonlinear mobility electrophoresis separation
DE19952322C2 (de) 1999-10-29 2002-06-13 Evotec Ag Verfahren und Vorrichtung zur Partikeltrennung
DE60130052T2 (de) * 2000-04-13 2008-05-15 Wako Pure Chemical Industries, Ltd. Elektroden-Bau für dielektrophoretische Anordnung und dielektrophoretische Trennung
US7033473B2 (en) * 2000-06-14 2006-04-25 Board Of Regents, University Of Texas Method and apparatus for combined magnetophoretic and dielectrophoretic manipulation of analyte mixtures
US20020121443A1 (en) * 2000-11-13 2002-09-05 Genoptix Methods for the combined electrical and optical identification, characterization and/or sorting of particles
DE10136275C1 (de) 2001-07-25 2002-12-12 Fraunhofer Ges Forschung Verfahren und Vorrichtung zur Probentrennung
US6783647B2 (en) * 2001-10-19 2004-08-31 Ut-Battelle, Llc Microfluidic systems and methods of transport and lysis of cells and analysis of cell lysate
US7156970B2 (en) * 2003-06-12 2007-01-02 Palo Alto Research Center Incorporated Distributed multi-segmented reconfigurable traveling wave grids for separation of proteins in gel electrophoresis
WO2007102839A2 (en) * 2005-10-27 2007-09-13 Applera Corporation Optoelectronic separation of biomolecules

Also Published As

Publication number Publication date
US8262883B2 (en) 2012-09-11
DE10311716A1 (de) 2004-10-14
EP1603678A1 (de) 2005-12-14
US20060289341A1 (en) 2006-12-28
WO2004082840A1 (de) 2004-09-30
EP1603678B1 (de) 2006-07-19
DE502004000991D1 (de) 2006-08-31
US9149813B2 (en) 2015-10-06
US20120305398A1 (en) 2012-12-06

Similar Documents

Publication Publication Date Title
ATE333323T1 (de) Verfahren und vorrichtung zur trennung von partikeln in einer flüssigkeitsströmung
Holmes et al. Microdevices for dielectrophoretic flow-through cell separation
DE60207412D1 (de) Verfahren, vorrichtung und einrichtung zur nasstrennung von magnetischen mikroteilchen
DE59903402D1 (de) Verfahren und vorrichtung zur manipulierung von mikropartikeln in fluidströmungen
ATE342512T1 (de) Vorrichtung und verfahren zum behandeln von magnetpartikeln
ATE472372T1 (de) Handhabung von magnetischen oder magnetisierbaren objekten unter verwendung von kombinierter magnetophorese und dielektrophorese
Cheng et al. Three-dimensional and analytical modeling of microfluidic particle transport in magnetic fluids
ATE535305T1 (de) Vorrichtung und verfahren zum abtrennen von magnetischen oder magnetisierbaren partikeln aus einer flüssigkeit
Lee et al. The potential of a dielectrophoresis activated cell sorter (DACS) as a next generation cell sorter
ATE520467T1 (de) Vorrichtung zur dielektrophoretischen trennung von partikeln in einer flüssigkeit
ATE471761T1 (de) Verfahren zum suspendieren oder resuspendieren von partikeln in einer lösung sowie daran angepasste vorrichtung
Honegger et al. Moving pulsed dielectrophoresis
ATE473809T1 (de) Verfahren und vorrichtung zur trennung von teilchen
US9968943B2 (en) Magnetic particle separator
ATE488301T1 (de) Verfahren und vorrichtung zur sammlung von suspendierten partikeln
US6866759B2 (en) Stepped electrophoresis for movement and concentration of DNA
US20040114458A1 (en) Device for mixing fluids
CN105772123A (zh) 一种基于微流控通道的磁分离方法及装置
Yousuff et al. Numerical modelling and simulation of dielectrophoretic based WBC sorting using sidewall electrodes
Zahangir et al. Single particle movement analysis in a continuous flow fluid with magnetophoresis effect
Guduru et al. Optimization of an Electrokinetic Orthogonal Electrode Pattern for Multifunctional System
Corral et al. Bioparticle Manipulation by an Orthogonal Electrode Preconcentrator
Aissa et al. Simulation of an hybrid blood cells micro-separator
Ji et al. Dielectrophoretic microfluidic chip with 3D vertical side-wall electrodes
Bai et al. Microparticle and Nanoparticle Manipulation

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee