ATE331735T1 - Verfahren zur monomerisierung von humanen serumalbumin-polymeren - Google Patents

Verfahren zur monomerisierung von humanen serumalbumin-polymeren

Info

Publication number
ATE331735T1
ATE331735T1 AT01978881T AT01978881T ATE331735T1 AT E331735 T1 ATE331735 T1 AT E331735T1 AT 01978881 T AT01978881 T AT 01978881T AT 01978881 T AT01978881 T AT 01978881T AT E331735 T1 ATE331735 T1 AT E331735T1
Authority
AT
Austria
Prior art keywords
human serum
serum albumin
multimer
uncorrected
monomers
Prior art date
Application number
AT01978881T
Other languages
English (en)
Inventor
Toshinobu Nouchi
Kikuchi-Shi
Hiroshi Mizokami
Yoshitaka Tajima
Hiroyuki Yokote
Satoshi Adachi
Yoshinobu Miyatsu
Tetsuro Tanabe
Yoshitaka Ushio
Shinichi Shibata
Original Assignee
Chemo Sero Therapeut Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2000324028A external-priority patent/JP4798831B2/ja
Priority claimed from JP2000324027A external-priority patent/JP4798830B2/ja
Application filed by Chemo Sero Therapeut Res Inst filed Critical Chemo Sero Therapeut Res Inst
Application granted granted Critical
Publication of ATE331735T1 publication Critical patent/ATE331735T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT01978881T 2000-10-24 2001-10-24 Verfahren zur monomerisierung von humanen serumalbumin-polymeren ATE331735T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000324028A JP4798831B2 (ja) 2000-10-24 2000-10-24 ヒト血清アルブミンのミスホールディングを抑制する方法
JP2000324027A JP4798830B2 (ja) 2000-10-24 2000-10-24 ヒト血清アルブミン多量体の単量体化方法

Publications (1)

Publication Number Publication Date
ATE331735T1 true ATE331735T1 (de) 2006-07-15

Family

ID=26602656

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01978881T ATE331735T1 (de) 2000-10-24 2001-10-24 Verfahren zur monomerisierung von humanen serumalbumin-polymeren

Country Status (11)

Country Link
US (1) US20030027991A1 (de)
EP (1) EP1329460B1 (de)
KR (1) KR100827750B1 (de)
CN (2) CN1275981C (de)
AT (1) ATE331735T1 (de)
AU (1) AU783571B2 (de)
CA (1) CA2395587C (de)
DE (1) DE60121196T2 (de)
DK (1) DK1329460T3 (de)
ES (1) ES2261487T3 (de)
WO (1) WO2002034785A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2866890B1 (fr) * 2004-02-27 2008-04-04 Lab Francais Du Fractionnement Procede de purification d'albumine comprenant une etape de nanofiltration, solution et composition a usage therapeutique la contenant
JP2005245269A (ja) * 2004-03-03 2005-09-15 Nipro Corp 血清アルブミン多量体を含む遺伝子組換え型蛋白質
US20130231287A1 (en) * 2010-02-25 2013-09-05 Parimala Nacharaju Pegylated albumin polymers and uses thereof
CN102241767B (zh) * 2011-06-22 2013-07-10 河南省医药科学研究院 一种牛血清白蛋白提取方法
KR101595151B1 (ko) * 2012-01-31 2016-02-18 이화여자대학교 산학협력단 일산화질소에 의해 형성되는 알부민 다량체 및 알부민 구조변형체
JP6928084B2 (ja) 2016-10-04 2021-09-01 アルブミディクス リミティド 組換え酵母由来血清アルブミンの使用
WO2020043087A1 (en) * 2018-08-27 2020-03-05 The Hong Kong University Of Science And Technology Method of detecting human serum albumin in biological fluids
CN109111498A (zh) * 2018-09-12 2019-01-01 山东省生物制品研究所 一种减少蛋白在protein L凝胶层析中形成多聚体的方法
US20230000774A1 (en) 2019-12-04 2023-01-05 Albumedix Limited Methods and compositions produced thereby

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169829A (en) * 1972-07-05 1979-10-02 Institut Merieux Process for the preparation of purified albumin and albumin obtained by said process
US4705848A (en) * 1986-06-02 1987-11-10 International Minerals & Chemical Corp. Isolation of bioactive, monomeric growth hormone
IL88326A (en) * 1987-11-18 1993-03-15 Gist Brocades Nv Purification of serum albumin
JPH0671434B2 (ja) * 1989-09-18 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法
US5440018A (en) * 1992-05-20 1995-08-08 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5521287A (en) * 1992-05-20 1996-05-28 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
EP0658569B2 (de) * 1993-12-17 2008-11-26 Mitsubishi Pharma Corporation Verfahren zum Entfärben von menschlichen Serum-Albumin
JP4798833B2 (ja) * 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 加熱処理工程を含むヒト血清アルブミンの製造方法
JP4798832B2 (ja) * 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 ヒト血清アルブミン多量体の除去方法

Also Published As

Publication number Publication date
DK1329460T3 (da) 2006-07-31
EP1329460A4 (de) 2004-08-11
EP1329460A1 (de) 2003-07-23
US20030027991A1 (en) 2003-02-06
WO2002034785A1 (fr) 2002-05-02
EP1329460B1 (de) 2006-06-28
AU1093402A (en) 2002-05-06
CN1651462A (zh) 2005-08-10
CA2395587A1 (en) 2002-05-02
DE60121196D1 (de) 2006-08-10
CN1406247A (zh) 2003-03-26
CA2395587C (en) 2012-09-18
KR20020065607A (ko) 2002-08-13
ES2261487T3 (es) 2006-11-16
CN1275981C (zh) 2006-09-20
KR100827750B1 (ko) 2008-05-07
AU783571B2 (en) 2005-11-10
DE60121196T2 (de) 2007-07-12

Similar Documents

Publication Publication Date Title
JP2005527470A5 (de)
WO2004043339A3 (en) Substituted cycloalkyl p1' hepatitis c virus inhibitors
ATE540054T1 (de) Antimikrobielle theta defensine und verfahren zu deren verwendung
WO2004032827A3 (en) Hepatitis c virus inhibitors
DE60334205D1 (en) Heterocyclische sulfonamid-hepatitis-c-virus-hemmer
HK1043543A1 (en) Modified factor VIII.
ATE331735T1 (de) Verfahren zur monomerisierung von humanen serumalbumin-polymeren
MXPA03004299A (es) Inhibidores de tripeptido de hepatitis c.
DE60234444D1 (de) Verfahren zur herstellung von l-aminosäuren mit stämmen der familie enterobacteriaceae
DE69739035D1 (de) Zusammensetzungen und Methoden zur Behandlung von Infektionen unter Verwendung von Indolicidinanalogen
ATE521357T1 (de) Verfahren zur behandlung von hepatitis
WO2002060468A3 (en) Antiviral activities of primate theta defensins and mammalian cathelicidins
DE60114002D1 (de) VERFAHREN ZUR HERSTELLUNG KRISTALLINEr PARTIKEL ZUR INHALATION
HK1048050A1 (en) Pharmaceutical composition for muscular anabolism
NZ592705A (en) 4-amino-4-oxobutanoyl peptide cyclic analogues, inhibitors of viral replication
EP1548107A4 (de) Chromoprotein und fluoroproteine
WO2008070347A3 (en) Betulin-peptide conjugates
UA94231C2 (ru) Олигонуклеотиды или их функциональные гомологи, композиция, которая содержит их, и способ лечения в-клеточной опухоли
ATE411812T1 (de) Peptide zur behandlung von infektionen mit dem herpes-virus
WO2006109174A3 (en) Hiv vaccine comprising a glycoprotein 120 signal sequence with no more than one positively charged amino acid
DE60330501D1 (de) Verfahren zur behandlung von verletzungen des nervensystems in verbindung mit einer blutung
MY142040A (en) Nitrosophenols and c-nitrosoanilines as polymerization inhibitors
DE60304603D1 (de) Plasma-albumin fraktion mit vermindertem prekallikrein
DE69917809D1 (de) Verwendung von bernsteisäure oder deren salze zur behandlung von insulinresistenz
WO2003064446A3 (en) Plasma protein-binding peptides from bacterial curli

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties