ATE327976T1 - Vorbeugung des verlustes und wiederherstellung von knochenmasse unter verwendung von prostaglandin-analogen - Google Patents

Vorbeugung des verlustes und wiederherstellung von knochenmasse unter verwendung von prostaglandin-analogen

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Publication number
ATE327976T1
ATE327976T1 AT97909544T AT97909544T ATE327976T1 AT E327976 T1 ATE327976 T1 AT E327976T1 AT 97909544 T AT97909544 T AT 97909544T AT 97909544 T AT97909544 T AT 97909544T AT E327976 T1 ATE327976 T1 AT E327976T1
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Austria
Prior art keywords
bone mass
preventing loss
prostaglandin analogues
recovering bone
recovering
Prior art date
Application number
AT97909544T
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English (en)
Inventor
Kimberly O'keefe Cameron
Hua Zhu Ke
Bruce Allen Lefker
Robert Louis Rosati
David Duane Thompson
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Pfizer
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Publication of ATE327976T1 publication Critical patent/ATE327976T1/de

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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
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    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C311/06—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by carboxyl groups
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