ATE322972T1 - System und verfahren zum uniaxialen pressen eines gegenstandes wie eine drei-dimensional gedruckte dosierungsform - Google Patents

System und verfahren zum uniaxialen pressen eines gegenstandes wie eine drei-dimensional gedruckte dosierungsform

Info

Publication number
ATE322972T1
ATE322972T1 AT02776381T AT02776381T ATE322972T1 AT E322972 T1 ATE322972 T1 AT E322972T1 AT 02776381 T AT02776381 T AT 02776381T AT 02776381 T AT02776381 T AT 02776381T AT E322972 T1 ATE322972 T1 AT E322972T1
Authority
AT
Austria
Prior art keywords
dosage form
pressing
compression
surface finish
result
Prior art date
Application number
AT02776381T
Other languages
English (en)
Inventor
Lewis Wendy E Pryce
Charles William Rowe
Michael J Cima
Peter A Materna
Original Assignee
Therics Inc
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therics Inc, Massachusetts Inst Technology filed Critical Therics Inc
Application granted granted Critical
Publication of ATE322972T1 publication Critical patent/ATE322972T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10—Processes of additive manufacturing
    • B29C64/165—Processes of additive manufacturing using a combination of solid and fluid materials, e.g. a powder selectively bound by a liquid binder, catalyst, inhibitor or energy absorber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y70/00—Materials specially adapted for additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
AT02776381T 2001-10-29 2002-10-29 System und verfahren zum uniaxialen pressen eines gegenstandes wie eine drei-dimensional gedruckte dosierungsform ATE322972T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33992001P 2001-10-29 2001-10-29

Publications (1)

Publication Number Publication Date
ATE322972T1 true ATE322972T1 (de) 2006-04-15

Family

ID=23331181

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02776381T ATE322972T1 (de) 2001-10-29 2002-10-29 System und verfahren zum uniaxialen pressen eines gegenstandes wie eine drei-dimensional gedruckte dosierungsform

Country Status (8)

Country Link
US (2) US7931914B2 (de)
EP (1) EP1439945B1 (de)
JP (2) JP4845340B2 (de)
AT (1) ATE322972T1 (de)
CA (1) CA2464478C (de)
DE (1) DE60210650T2 (de)
ES (1) ES2262851T3 (de)
WO (1) WO2003037607A1 (de)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001034371A2 (en) 1999-11-05 2001-05-17 Z Corporation Material systems and methods of three-dimensional printing
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US8313775B2 (en) 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
JP2006528185A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8313776B2 (en) 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
WO2005016311A1 (en) 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Robust pellet
JP2007502294A (ja) 2003-08-12 2007-02-08 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
EP1658034A4 (de) 2003-08-29 2011-06-22 Middlebrook Pharmaceuticals Inc Antibiotisches produkt, seine verwendung und formulierung
JP2007513869A (ja) 2003-09-15 2007-05-31 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8080097B2 (en) * 2003-11-06 2011-12-20 Hewlett-Packard Development Company, L.P. System and a method for the creation of edible, optically invisible images
JP2008505124A (ja) 2004-07-02 2008-02-21 アドバンシス ファーマスーティカル コーポレイション パルス送達用錠剤
US8609198B2 (en) * 2004-07-21 2013-12-17 Hewlett-Packard Development Company, L.P. Pharmaceutical dose form with a patterned coating and method of making the same
ES2555152T3 (es) * 2004-11-26 2015-12-29 Aprecia Pharmaceuticals Co. Formas de dosificación impresas en tres dimensiones
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
EP2664442B1 (de) 2006-12-08 2018-02-14 3D Systems Incorporated Dreidimensionales Druckmaterialsystem
JP5129267B2 (ja) 2007-01-10 2013-01-30 スリーディー システムズ インコーポレーテッド 改良された色、物品性能及び使用の容易さ、を持つ３次元印刷材料システム
US7968626B2 (en) 2007-02-22 2011-06-28 Z Corporation Three dimensional printing material system and method using plasticizer-assisted sintering
CN102470237A (zh) 2009-06-26 2012-05-23 塔里斯生物医药公司 用于可植入药物递送装置的固体药物片剂
JP2011074015A (ja) * 2009-09-30 2011-04-14 Tomita Pharmaceutical Co Ltd 固形製剤及びその製造方法
US9381154B2 (en) 2011-06-09 2016-07-05 Xerox Corporation Direct inkjet fabrication of drug delivery devices
US8414654B1 (en) * 2011-11-23 2013-04-09 Amendia, Inc. Bone implants and method of manufacture
JP6509117B2 (ja) 2012-08-31 2019-05-08 ボルケーノ コーポレイション 血管内装置のコンポーネントの取り付け構造
EP2892708B1 (de) 2012-09-05 2018-10-10 Aprecia Pharmaceuticals LLC Dreidimensionales drucksystem und vorrichtungsanordnung
US8888480B2 (en) 2012-09-05 2014-11-18 Aprecia Pharmaceuticals Company Three-dimensional printing system and equipment assembly
JP6466399B2 (ja) * 2013-03-15 2019-02-06 アプレシア・ファーマスーティカルズ・カンパニー トピラマートの急速分散性の剤形
WO2014144512A1 (en) * 2013-03-15 2014-09-18 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
US10471497B2 (en) 2013-08-16 2019-11-12 The Exone Company Three-dimensional printed metal-casting molds and methods for making the same
US9289917B2 (en) * 2013-10-01 2016-03-22 General Electric Company Method for 3-D printing a pattern for the surface of a turbine shroud
WO2015057761A1 (en) 2013-10-17 2015-04-23 The Exone Company Three-dimensional printed hot isostatic pressing containers and processes for making same
EP2884259A1 (de) * 2013-12-11 2015-06-17 Rockwool International A/S Verfahren zur Erkennung der Aushärtung des Bindemittels in einem Mineralfaserprodukt
US20160332373A1 (en) 2013-12-23 2016-11-17 The Exone Company Methods and Systems for Three-Dimensional Printing Utilizing Multiple Binder Fluids
WO2015100084A1 (en) 2013-12-23 2015-07-02 The Exone Company Method of three-dimensional printing using a multi-component build powder
US9415546B2 (en) * 2014-01-29 2016-08-16 Xerox Corporation System and method for controlling material drop volume in three dimensional object printing
WO2015183796A1 (en) 2014-05-29 2015-12-03 The Exone Company Process for making nickel-based superalloy articles by three-dimensional printing
US9738032B2 (en) 2014-06-06 2017-08-22 Xerox Corporation System for controlling operation of a printer during three-dimensional object printing with reference to a distance from the surface of object
US9446556B2 (en) 2014-06-06 2016-09-20 Xerox Corporation System for compensating for drop volume variation during three-dimensional printing of an object
US9327537B2 (en) 2014-06-06 2016-05-03 Xerox Corporation System for adjusting operation of a printer during three-dimensional object printing using an optical sensor
US20170203514A1 (en) 2014-07-17 2017-07-20 The Exone Company Methods and Apparatuses for Curing Three-Dimensional Printed Articles
US9857784B2 (en) * 2014-11-12 2018-01-02 International Business Machines Corporation Method for repairing with 3D printing
EP3227109B1 (de) 2014-12-03 2020-08-19 The Exone Company Verfahren zur herstellung von verdichteten kohlenstoffartikeln durch dreidimensionales drucken
CN206120770U (zh) * 2015-06-03 2017-04-26 南京三迭纪医药科技有限公司 药品剂型
AU2016272089B2 (en) 2015-06-03 2021-02-18 Triastek, Inc. Dosage forms and use thereof
BR112018001609A2 (pt) 2015-08-21 2018-09-18 Aprecia Pharmaceuticals LLC sistema e montagem de equipamento de impressão tridimensional
CN105196550B (zh) * 2015-10-30 2018-01-23 兰红波 一种单喷头多材料多尺度3d打印装置及其工作方法
CN107019676B (zh) * 2016-01-29 2020-08-04 南京三迭纪医药科技有限公司 一种抗凝血药物的制备方法
JP2019512468A (ja) * 2016-03-18 2019-05-16 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 浮遊性の薬学的剤形
CN105687151A (zh) * 2016-03-22 2016-06-22 西北工业大学 一种基于喷墨3d打印技术制备片剂药物的方法
EP3452003A4 (de) 2016-05-05 2019-06-26 Triastek, Inc. Dosierungsform mit kontrollierter freisetzung
US10765658B2 (en) 2016-06-22 2020-09-08 Mastix LLC Oral compositions delivering therapeutically effective amounts of cannabinoids
WO2018028972A1 (en) 2016-08-08 2018-02-15 Ratiopharm Gmbh Method for manufacturing a dosage form by additive manufacturing, a dosage form and a device for manufacturing a dosage form
JP6592800B2 (ja) * 2016-08-17 2019-10-23 株式会社マイクロジェット 成型物を成型するシステム
WO2018151725A1 (en) * 2017-02-15 2018-08-23 Hewlett-Packard Development Company, L.P. Printed support structure
WO2018156141A1 (en) * 2017-02-24 2018-08-30 Hewlett-Packard Development Company, L.P. Three-dimensional (3d) printing a pharmaceutical tablet
WO2018218203A1 (en) 2017-05-26 2018-11-29 Philip Brunner Water soluble polymer compositions
EP3701038A1 (de) * 2017-10-26 2020-09-02 Merck Patent GmbH Verfahren zur durchführung einer zellkultur
KR20230079242A (ko) 2017-12-29 2023-06-05 락손 메디칼 아게 약물 전달 시스템을 제조하기 위한 방법
KR20200111705A (ko) * 2017-12-29 2020-09-29 락손 메디칼 아게 약물 전달 시스템
CN116270513A (zh) 2018-01-09 2023-06-23 南京三迭纪医药科技有限公司 一种包含固定剂量adhd非***和adhd***的复方口服药物剂型
US10350822B1 (en) 2018-01-09 2019-07-16 Triastek Inc. Dosage forms with desired release profiles and methods of designing and making thereof
WO2019139594A1 (en) 2018-01-11 2019-07-18 Hewlett-Packard Development Company, L.P. Build material spreaders
JP2022533213A (ja) * 2019-05-21 2022-07-21 ディーエフイー ファーマ ゲーエムベーハー ウント コー カーゲー ラクトース粉末床３次元印刷
US11583501B1 (en) * 2020-01-02 2023-02-21 Robert Edwin Douglas Method and apparatus for 3D printing a precision pharmacologic dosing regimen
WO2021176360A1 (en) * 2020-03-02 2021-09-10 Craft Health Pte Ltd Oral dosage forms for extended drug release
US20230390193A1 (en) 2020-10-30 2023-12-07 Triastek, Inc. Gastroretentive pharmaceutical dosage form
WO2023235372A1 (en) * 2022-06-01 2023-12-07 Cyrus Scientific, Llc Pharmaceutical apparatus and method of manufacturing a patient-tailored pharmaceutical tablet

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4865789A (en) * 1983-11-14 1989-09-12 Akzo Nv Method for making porous structures
US5204055A (en) 1989-12-08 1993-04-20 Massachusetts Institute Of Technology Three-dimensional printing techniques
US5490962A (en) * 1993-10-18 1996-02-13 Massachusetts Institute Of Technology Preparation of medical devices by solid free-form fabrication methods
US6280771B1 (en) 1997-02-20 2001-08-28 Therics, Inc. Dosage forms exhibiting multi-phasic release kinetics and methods of manufacture thereof
DE4439782B4 (de) * 1993-11-05 2005-07-28 Sanyo Electric Co., Ltd., Moriguchi Behälter, der mit einer Anzahl von Pulvern von wasserstoffabsorbierenden Legierungen gepackt ist, und Formkörper
US5587203A (en) * 1993-11-29 1996-12-24 Nippon Oil Co. Method for preparing a carbon/carbon composite material
ES2318869T3 (es) * 1997-02-20 2009-05-01 Massachusetts Institute Of Technology Forma de dosificacion que presenta propiedades de dispersion rapida, metodos de uso y procedimiento para su fabricacion.
EP1014950B1 (de) * 1997-02-20 2013-10-30 Massachusetts Institute of Technology Dosierungsformen mit mehrphasigen freisetzungskinetiken und methoden zu ihrer herstellung
JP2002527144A (ja) * 1998-10-12 2002-08-27 セリックス， インコーポレイテッド 組織再生のための複合体およびその製造方法
JP3756017B2 (ja) * 1999-08-12 2006-03-15 株式会社リコー 定着装置
ATE315930T1 (de) * 2000-05-18 2006-02-15 Therics Inc Einkapselung eines toxischen kerns in einen nicht-toxischen bereich in einer oralen darreichungsform

Also Published As

Publication number Publication date
DE60210650D1 (de) 2006-05-24
ES2262851T3 (es) 2006-12-01
US8758658B2 (en) 2014-06-24
US20030143268A1 (en) 2003-07-31
CA2464478A1 (en) 2003-05-08
JP4845340B2 (ja) 2011-12-28
WO2003037607A1 (en) 2003-05-08
JP2010227590A (ja) 2010-10-14
DE60210650T2 (de) 2007-01-25
US20110187015A1 (en) 2011-08-04
EP1439945A1 (de) 2004-07-28
US7931914B2 (en) 2011-04-26
JP2005507723A (ja) 2005-03-24
EP1439945B1 (de) 2006-04-12
CA2464478C (en) 2012-03-20

Similar Documents

Publication Publication Date Title
ATE322972T1 (de) System und verfahren zum uniaxialen pressen eines gegenstandes wie eine drei-dimensional gedruckte dosierungsform
CN104807685B (zh) 利用3d打印制作含特定几何特征结构面的节理试样方法
WO2009066572A1 (ja) プレス成形方法およびプレス成形装置
DE602005012951D1 (de) Mittels verfahren aus einachsiger verdichtung, sinterung und oberflächenverdichtung hergestellte zahnräder auf eisenbasis
Reiterer et al. Finite element simulation of cold isostatic pressing and sintering of SiC components
CN110388201A (zh) 一种模拟水力压裂裂缝真实形态的人造岩样制作方法
CA2450427A1 (en) Method of preparation of high density soft magnetic products
Koerner Triaxial stress state compaction of powders
Frykholm et al. Press and sintering of titanium
BR0314079B1 (pt) processo para preparação de compactos não sinterizados de alta densidade.
Cante et al. On numerical simulation of powder compaction process: powder transfer modelling and characterisation
Shinohara et al. Effect of heat treatment of alumina granules on the compaction behavior and properties of green and sintered bodies
CN204718854U (zh) 一种压制人工岩心样品的模具
Eckert et al. Application of compaction equations for powdered pharmaceutical materials
CN104496456B (zh) 一种钴铁氧体磁致伸缩材料的制备方法
CN206733670U (zh) 一种高效粉尘压片模具
Fu et al. Effect of cyclic pressure consolidation on the uniformity of metal matrix composites
CN204085976U (zh) 一种便携式土遗址土样试块制备的装置
Dias Theoretical and experimental analysis of plasticity equations for porous metals
CN107246989A (zh) 一种实验室注浆水泥土的制备方法
ATE145640T1 (de) Verfahren zur herstellung eines implantates
Hirose et al. Prediction for sintering deformation of fine powder compact
CN112255059A (zh) 一种3d打印光敏树脂岩体试样的增脆方法
Okor Brittle fracture during tableting-a problem for the pharmaceutical industry
CN103934455B (zh) 一种碱金属蒸发器用蒸发粉体的成型模具及成型方法

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties