ATE321784T1 - Pthrp analogen - Google Patents

Pthrp analogen

Info

Publication number
ATE321784T1
ATE321784T1 AT97951595T AT97951595T ATE321784T1 AT E321784 T1 ATE321784 T1 AT E321784T1 AT 97951595 T AT97951595 T AT 97951595T AT 97951595 T AT97951595 T AT 97951595T AT E321784 T1 ATE321784 T1 AT E321784T1
Authority
AT
Austria
Prior art keywords
pthrp analogue
pthrp
analogue
Prior art date
Application number
AT97951595T
Other languages
English (en)
Inventor
Zheng Xin Dong
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/779,768 external-priority patent/US5969095A/en
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of ATE321784T1 publication Critical patent/ATE321784T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT97951595T 1997-01-07 1997-12-08 Pthrp analogen ATE321784T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/779,768 US5969095A (en) 1995-07-13 1997-01-07 Analogs of parathyroid hormone
US08/813,534 US5955574A (en) 1995-07-13 1997-03-07 Analogs of parathyroid hormone

Publications (1)

Publication Number Publication Date
ATE321784T1 true ATE321784T1 (de) 2006-04-15

Family

ID=27119618

Family Applications (2)

Application Number Title Priority Date Filing Date
AT97951595T ATE321784T1 (de) 1997-01-07 1997-12-08 Pthrp analogen
AT05026436T ATE471342T1 (de) 1997-01-07 1997-12-08 Parathyroidhormon analoge

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT05026436T ATE471342T1 (de) 1997-01-07 1997-12-08 Parathyroidhormon analoge

Country Status (24)

Country Link
US (1) US5955574A (de)
EP (3) EP0948541B1 (de)
JP (1) JP3963482B2 (de)
KR (2) KR100699422B1 (de)
CN (1) CN1137898C (de)
AR (3) AR011517A1 (de)
AT (2) ATE321784T1 (de)
AU (1) AU741584B2 (de)
BR (1) BR9714200A (de)
CA (1) CA2276614C (de)
CZ (2) CZ298937B6 (de)
DE (2) DE69735603T2 (de)
DK (2) DK0948541T3 (de)
ES (2) ES2347154T3 (de)
HK (1) HK1026215A1 (de)
HU (1) HUP9904596A3 (de)
IL (1) IL130794A0 (de)
NO (1) NO993341L (de)
NZ (1) NZ336610A (de)
PL (1) PL191898B1 (de)
PT (2) PT1645566E (de)
RU (1) RU2198182C2 (de)
SI (2) SI0948541T1 (de)
WO (1) WO1998030590A2 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7410948B2 (en) * 1995-07-13 2008-08-12 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Analogs of parathyroid hormone
US6544949B1 (en) * 1995-07-13 2003-04-08 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Analogs of parathyroid hormone
RS49707B (sr) * 1997-09-09 2007-12-31 F.Hoffmann-La Roche Ag., Primena polipeptidnog analoga peptida srodnog paratireoidnom hormonu i njegovih soli za proizvodnju medikamenata za lečenje preloma kostiju
AU3673699A (en) * 1998-05-05 1999-11-23 Beth Israel Deaconess Medical Center Pth2 receptor selective compounds
PL345583A1 (en) * 1998-07-20 2001-12-17 Sod Conseils Rech Applic Peptide analogues of pacap
US6660843B1 (en) † 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
WO2001060862A1 (en) * 2000-02-18 2001-08-23 Dabur Research Foundation Vasoactive intestinal peptide analogs
US6756480B2 (en) * 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US20050124537A1 (en) * 2000-04-27 2005-06-09 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
BRPI0209748B1 (pt) 2001-06-01 2015-11-24 Novartis Ag composição farmacêutica para administração oral compreendendo hormonio paratireoide(pth), e seu uso
US7572765B2 (en) 2001-07-23 2009-08-11 The General Hospital Corporation Conformationally constrained parathyroid hormone (PTH) analogs
MXPA06001428A (es) * 2003-08-06 2006-05-15 Rhodia Metodo para promover el crecimiento del hueso.
CN101355959B (zh) 2005-11-10 2013-02-27 密歇根理工大学管理委员会 黑熊甲状旁腺素和使用黑熊甲状旁腺素的方法
US7803770B2 (en) 2006-10-03 2010-09-28 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
PT2957278T (pt) * 2006-10-03 2017-08-23 Ipsen Pharma Sas Uma composição estável compreendendo pthrp e utilizações da mesma
USRE49444E1 (en) 2006-10-03 2023-03-07 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
WO2008048784A1 (en) * 2006-10-13 2008-04-24 Eli Lilly And Company Pegylated pth as pth receptor modulators and uses thereof
BRPI0814962B8 (pt) 2007-08-01 2021-05-25 Chugai Pharmaceutical Co Ltd métodos in vitro para determinar se um composto candidato é um agonista de longa duração ou de curta duração de um receptor acoplado à proteína g, polipeptídeo, seu uso e composição farmacêutica
CN102448482A (zh) 2009-03-27 2012-05-09 范安德尔研究所 甲状旁腺素肽和甲状旁腺素相关蛋白肽及使用方法
CA2782640A1 (en) 2009-12-07 2011-06-16 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
ME02474B (de) 2010-05-12 2017-02-20 Radius Health Inc Therapiepläne
JP5941040B2 (ja) 2010-05-13 2016-06-29 ザ ジェネラル ホスピタル コーポレイション 副甲状腺ホルモン類似体およびその使用
BR112013007685B1 (pt) 2010-09-28 2021-11-09 Radius Pharmaceuticals, Inc Compostos moduladores de receptor andrógeno seletivos, composição farmacêutica compreendendo os referidos compostos, método de identificação de um composto capaz de modular um receptor andrógeno, usos de um composto ou da composição e processo para a preparação de um composto
IL297369B1 (en) 2015-04-29 2024-02-01 Radius Pharmaceuticals Inc RAD for use in a method to treat mutant estrogen receptor positive breast cancer or mutant estrogen receptor positive ovarian cancer
US20180161401A1 (en) * 2015-07-06 2018-06-14 Zheng Xin Dong Novel Formulations of PTHrP Analogue
RU2769527C2 (ru) 2016-06-22 2022-04-01 Эллипсес Фарма Лтд Способы лечения ar+ рака молочной железы
KR102322802B1 (ko) 2017-01-05 2021-11-04 래디어스 파마슈티컬스, 인코포레이티드 Rad1901-2hcl의 다형 형태
US10996208B2 (en) 2017-04-28 2021-05-04 Radius Health, Inc. Abaloparatide formulations and methods of testing, storing, modifying, and using same
US11643385B2 (en) 2018-07-04 2023-05-09 Radius Pharmaceuticals, Inc. Polymorphic forms of RAD1901-2HCl

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
FR2550204B1 (fr) * 1983-08-05 1987-11-13 Toyo Jozo Kk Derives peptidiques de (nle8,nle1b, tyr34)-h-pth
EP0293158A3 (de) * 1987-05-26 1990-05-09 Merck & Co. Inc. Parathyroide Hormon-Antagonisten
WO1990010067A1 (de) * 1989-02-23 1990-09-07 GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) Pth-varianten kodierende dna-sequenzen, pth-varianten, expressionsvektor, bakterieller wirt, verwendung und therapeutische zusammensetzung
CA2040264A1 (en) * 1990-04-12 1991-10-13 Tatsuhiko Kanmera Parathyroid hormone antagonists
JPH0532696A (ja) * 1990-09-28 1993-02-09 Takeda Chem Ind Ltd 副甲状腺ホルモン誘導体
AU2807892A (en) * 1991-10-10 1993-05-03 Peter K.T. Pang Parathyroid hormone analogues and use in osteoporosis treatment
US5434246A (en) * 1992-03-19 1995-07-18 Takeda Chemical Industries, Ltd. Parathyroid hormone derivatives
CA2098639A1 (en) * 1992-06-19 1993-12-20 K. Anne Kronis Bone stimulating, non-vasoactive parathyroid hormone variants
US5821225A (en) * 1992-07-14 1998-10-13 Syntex (U.S.A.) Inc. Method for the treatment of corticosteroid induced osteopenia comprising administration of modified PTH or PTHrp
US5589452A (en) * 1992-07-14 1996-12-31 Syntex (U.S.A.) Inc. Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
AU672790B2 (en) * 1992-07-15 1996-10-17 Novartis Ag Variants of parathyroid hormone and its fragments
HU220137B (hu) 1993-01-06 2001-11-28 Kinerton Ltd. Biológiailag lebontható poliészterek és biológiailag aktív polipeptidek ionos molekuláris konjugátumai, eljárás ezek előállítására és eljárás mikrorészecskék előállítására
CN1070500C (zh) * 1993-07-13 2001-09-05 森德克斯(美国)股份有限公司 甲状旁腺激素类似物和甲状旁腺激素相关肽：合成和治疗骨质疏松症的用途
EP0800405A4 (de) * 1994-12-19 1998-11-11 Beth Israel Hospital Kontinuierliche niedrigdosierte verabreichung von parathyroidhormon oder deren agonist
CA2178894A1 (en) * 1995-06-15 1996-12-16 Tsunehiko Fukuda Parathyroid hormone derivatives and their use
US5723577A (en) * 1995-07-13 1998-03-03 Biomeasure Inc. Analogs of parathyroid hormone

Also Published As

Publication number Publication date
CZ298937B6 (cs) 2008-03-19
ES2347154T3 (es) 2010-10-26
AU5519998A (en) 1998-08-03
NO993341L (no) 1999-09-06
CZ239899A3 (cs) 2000-01-12
SI1645566T1 (sl) 2010-11-30
PT948541E (pt) 2006-07-31
DE69735603T2 (de) 2006-11-30
EP1645566B1 (de) 2010-06-16
NZ336610A (en) 2001-07-27
KR100699422B1 (ko) 2007-03-28
PL334438A1 (en) 2000-02-28
WO1998030590A3 (en) 1998-12-10
CN1137898C (zh) 2004-02-11
WO1998030590A9 (en) 1999-08-19
AR051906A2 (es) 2007-02-14
HUP9904596A1 (hu) 2000-06-28
KR100497709B1 (ko) 2005-06-23
DE69739912D1 (de) 2010-07-29
DK1645566T3 (da) 2010-09-27
AU741584B2 (en) 2001-12-06
DK0948541T3 (da) 2006-07-17
KR20060030006A (ko) 2006-04-07
HK1026215A1 (en) 2000-12-08
NO993341D0 (no) 1999-07-06
PL191898B1 (pl) 2006-07-31
ATE471342T1 (de) 2010-07-15
EP0948541A2 (de) 1999-10-13
RU2198182C2 (ru) 2003-02-10
PT1645566E (pt) 2010-08-31
EP1645566A3 (de) 2006-10-11
CA2276614A1 (en) 1998-07-16
DE69735603D1 (de) 2006-05-18
JP2001508439A (ja) 2001-06-26
HUP9904596A3 (en) 2000-07-28
US5955574A (en) 1999-09-21
EP0948541B1 (de) 2006-03-29
CA2276614C (en) 2002-06-11
EP1645566A2 (de) 2006-04-12
ES2258286T3 (es) 2006-08-16
AR011517A1 (es) 2000-08-30
JP3963482B2 (ja) 2007-08-22
WO1998030590A2 (en) 1998-07-16
BR9714200A (pt) 2000-03-28
AR038552A2 (es) 2005-01-19
KR20000069952A (ko) 2000-11-25
CZ301497B6 (cs) 2010-03-24
EP2206725A1 (de) 2010-07-14
IL130794A0 (en) 2001-01-28
CN1254347A (zh) 2000-05-24
SI0948541T1 (sl) 2006-06-30

Similar Documents

Publication Publication Date Title
ATE321784T1 (de) Pthrp analogen
ATA93198A (de) Fluoxetinpellets
DE59807164D1 (de) Sägerät
ID20285A (id) Katrol tangan
ATA111897A (de) Kimme
DK0862850T3 (da) Mejetærsker
NO20002555D0 (no) Skjøt
ATA112597A (de) Snowboard - bindung
DE69801242T2 (de) Düngerstreuer
DE29722394U1 (de) Arbeitsgerät
DE29713277U1 (de) Bohnenstangen-Set
FI972138A0 (fi) Returtraog i bestrykningsanordning
ATA86797A (de) Verschleissschuh
BR9701194A (pt) Hidrociclo
ATA46498A (de) Kunststoffgleitbahn
FR2771676B1 (fr) Livre
KR970019330U (ko) 상표
ITDP970013A1 (it) Ruota singola - attrezzo sportivo - cicloidi
FI970361A (fi) Kukkamaljakko
BR7702215U (pt) Conjunto pia-fogão
BR9700328A (pt) Conjunto tampa-recipiente
ATE421585T1 (de) Motlinhomologe
FI974373A0 (fi) Avgasutlopp i utombordsmotorer
FI974354A0 (fi) Kvaevereducering i avloppsvatten
FI974635A0 (fi) I vaermebatteri integrerbar ventilkonstruktion

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0948541

Country of ref document: EP

EEIH Change in the person of patent owner