ATE320417T1 - Naphthimidobenzamid-derivate - Google Patents

Naphthimidobenzamid-derivate

Info

Publication number
ATE320417T1
ATE320417T1 AT99926895T AT99926895T ATE320417T1 AT E320417 T1 ATE320417 T1 AT E320417T1 AT 99926895 T AT99926895 T AT 99926895T AT 99926895 T AT99926895 T AT 99926895T AT E320417 T1 ATE320417 T1 AT E320417T1
Authority
AT
Austria
Prior art keywords
hydrogen atom
different
same
independently represents
naphthimidobenzamide
Prior art date
Application number
AT99926895T
Other languages
English (en)
Inventor
Kazuharu Noguchi
Motoji Wakida
Kenji Suzuki
Yuji Yamada
Tetsuji Asao
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE320417T1 publication Critical patent/ATE320417T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT99926895T 1998-07-03 1999-07-02 Naphthimidobenzamid-derivate ATE320417T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18907898 1998-07-03

Publications (1)

Publication Number Publication Date
ATE320417T1 true ATE320417T1 (de) 2006-04-15

Family

ID=16234950

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99926895T ATE320417T1 (de) 1998-07-03 1999-07-02 Naphthimidobenzamid-derivate

Country Status (9)

Country Link
US (1) US6300331B1 (de)
EP (1) EP1020446B1 (de)
JP (1) JP3357662B2 (de)
KR (1) KR100364205B1 (de)
AT (1) ATE320417T1 (de)
AU (1) AU727591B2 (de)
CA (1) CA2300069C (de)
DE (1) DE69930383T2 (de)
WO (1) WO2000001672A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998017278A1 (en) * 1996-10-21 1998-04-30 Allelix Biopharmaceuticals Inc. Neurotrophin antagonist compositions
US6468990B1 (en) * 1999-05-17 2002-10-22 Queen's University At Kingston Method of inhibiting binding of nerve growth factor to p75 NTR receptor
US6492380B1 (en) * 1999-05-17 2002-12-10 Queen's University At Kingston Method of inhibiting neurotrophin-receptor binding
AU2005201951C1 (en) * 1999-05-17 2009-07-16 Queen's University Method of inhibiting neurotrophin-receptor binding
BRPI0615930A2 (pt) 2005-09-15 2016-08-23 Painceptor Pharma Corp métodos de modular a interação de uma neurotrofina e um receptor de neurotrofina, de tratar dor em um indivíduo, de tratar distúrbio inflamatório em um indivíduo, de tratar um distúrbio neurológico em um indivíduo, e de tratar uma doença ou distúrbio associado aos sistemas geniturinário e/ou gastrointestinal de um indivíduo, e, composto
EP2050747A1 (de) * 2007-10-12 2009-04-22 BioAlliance Pharma Harmol- bzw. Harmolderivat-Dimere und deren Verwendung
US8420665B2 (en) 2008-01-11 2013-04-16 Northwestern University Anti-cancer compounds
GB2469980B (en) * 2008-03-05 2012-02-22 Council Scient Ind Res Naphthalimide-benzimidazole hybrids as potential antitumour agents and process for the preparation thereof
JP2012077045A (ja) * 2010-10-05 2012-04-19 Toray Fine Chemicals Co Ltd 高純度ジアシル誘導体
JP5834390B2 (ja) * 2010-10-05 2015-12-24 東レ・ファインケミカル株式会社 ジアシル誘導体の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0125439B1 (de) 1983-04-01 1990-01-24 Warner-Lambert Company 3,6-Disubstituierte-1,8-Naphthalimide, Verfahren zu ihrer Herstellung und ihre Verwendung
DE3942280A1 (de) * 1989-12-21 1991-06-27 Knoll Ag N-substituierte naphthalimide, ihre herstellung und verwendung
US5086059A (en) * 1990-06-07 1992-02-04 Du Pont Merck Pharmaceutical Company Bis-naphthalimides as anticancer agents
US5206249A (en) 1991-03-27 1993-04-27 Du Pont Merck Pharmaceutical Company Bis-naphthalimides containing amino-acid derived linkers as anticancer agents
WO1993012092A1 (en) * 1991-12-11 1993-06-24 The Du Pont Merck Pharmaceutical Company Highly water soluble bis-naphthalimides useful as anticancer agents

Also Published As

Publication number Publication date
KR20010023464A (ko) 2001-03-26
CA2300069A1 (en) 2000-01-13
AU727591B2 (en) 2000-12-14
KR100364205B1 (ko) 2002-12-11
CA2300069C (en) 2006-01-17
DE69930383D1 (de) 2006-05-11
DE69930383T2 (de) 2006-10-05
JP3357662B2 (ja) 2002-12-16
AU4396399A (en) 2000-01-24
US6300331B1 (en) 2001-10-09
EP1020446A4 (de) 2001-11-07
EP1020446A1 (de) 2000-07-19
WO2000001672A1 (fr) 2000-01-13
EP1020446B1 (de) 2006-03-15

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties