ATE316530T1 - Verfahren zur herstellung von 2-(7-chloro-1,8- - Google Patents

Verfahren zur herstellung von 2-(7-chloro-1,8-

Info

Publication number: ATE316530T1
Authority: AT; Austria
Prior art keywords: chloro; producing
Prior art date: 2002-03-29

Application number

AT03708410T

Other languages

English (en)

Inventor

T L Stuk

S M Jennings

Original Assignee

Indevus Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-29

Filing date

2003-03-17

Publication date

2006-02-15

2003-03-17 Application filed by Indevus Pharmaceuticals Inc filed Critical Indevus Pharmaceuticals Inc

2006-02-15 Application granted granted Critical

2006-02-15 Publication of ATE316530T1 publication Critical patent/ATE316530T1/de

Links

238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Anesthesiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT03708410T 2002-03-29 2003-03-17 Verfahren zur herstellung von 2-(7-chloro-1,8- ATE316530T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US36860902P	2002-03-29	2002-03-29

Publications (1)

Publication Number	Publication Date
ATE316530T1 true ATE316530T1 (de)	2006-02-15

Family

ID=28675512

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03708410T ATE316530T1 (de)	2002-03-29	2003-03-17	Verfahren zur herstellung von 2-(7-chloro-1,8-

Country Status (17)

Country	Link
US (3)	US6949653B2 (de)
EP (1)	EP1490363B1 (de)
JP (1)	JP4471664B2 (de)
AR (1)	AR039169A1 (de)
AT (1)	ATE316530T1 (de)
AU (1)	AU2003212585B2 (de)
CA (1)	CA2480776C (de)
CY (1)	CY1105785T1 (de)
DE (1)	DE60303363T2 (de)
DK (1)	DK1490363T3 (de)
ES (1)	ES2256723T3 (de)
IL (2)	IL164377A0 (de)
NZ (1)	NZ535685A (de)
PT (1)	PT1490363E (de)
RU (1)	RU2318823C2 (de)
TW (1)	TWI237639B (de)
WO (1)	WO2003082870A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK1490363T3 (da) *	2002-03-29	2006-05-15	Indevus Pharmaceuticals Inc	Fremgangsmåder til fremstilling af 2-7-chlor-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxo-hexyl)1-isoindolinon
CN109988164B (zh) *	2017-12-31	2021-12-07	中国医学科学院药物研究所	盐酸小檗碱与苹果酸共晶物及制备方法和其组合物与用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR208414A1 (es)	1974-11-07	1976-12-27	Rhone Poulenc Ind	Procedimiento para obtener nuevos derivados de la((acil-4piperazinil-1)carboniloxi-5 pirrolinona-2)
FR2607503B1 (fr)	1986-12-02	1989-02-24	Rhone Poulenc Sante	Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
US5532228A (en) *	1990-02-06	1996-07-02	Schering Aktiengesellschaft	Side-chain homologous vitamin D derivatives, process for their production, pharmaceutical preparations containing these derivatives and their use as pharmaceutical agents
FR2678934B1 (fr)	1991-07-12	1995-01-13	Rhone Poulenc Rorer Sa	Procede de preparation de l'isomere dextrogyre d'un derive de l'isoindolinone.
FR2678932B1 (fr)	1991-07-12	1993-09-24	Rhone Poulenc Rorer Sa	Procede de preparation des isomeres optiques d'un derive de l'amino-2 naphtyridine.
FR2678933B1 (fr)	1991-07-12	1993-09-24	Rhone Poulenc Rorer Sa	Procede de preparation des isomeres optiques d'un derive de l'amino-2 naphtyridine.
FR2681068B1 (fr)	1991-09-09	1993-11-19	Rhone Poulenc Rorer Sa	Procede de preparation de l'isomere dextrogyre d'un derive de l'isoindolinone.
FR2684673B1 (fr)	1991-12-04	1994-01-21	Rhone Poulenc Rorer Sa	Procede de preparation d'un derive de l'amino-2 naphtyridine racemique.
FR2685330B1 (fr)	1991-12-20	1994-02-04	Rhone Poulenc Rorer Sa	Procede de preparation des enantiomeres d'un derive de l'isoindolinone.
FR2687154B1 (fr)	1992-02-07	1995-05-12	Rhone Poulenc Rorer Sa	Nouveau derive de l'isoindolinone, sa preparation et les compositions pharmaceutiques qui le contiennent.
FR2695389B1 (fr)	1992-09-08	1994-11-04	Rhone Poulenc Rorer Sa	Nouveau dérivé de l'isoindolinone, sa préparation et les compositions pharmaceutiques qui le contiennent.
US5498716A (en)	1994-01-12	1996-03-12	Rhone-Poulenc Rorer S.A.	2-amino naphthyridine derivative, its preparation and its use
DK1490363T3 (da) *	2002-03-29	2006-05-15	Indevus Pharmaceuticals Inc	Fremgangsmåder til fremstilling af 2-7-chlor-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxo-hexyl)1-isoindolinon

2003
- 2003-03-17 DK DK03708410T patent/DK1490363T3/da active
- 2003-03-17 PT PT03708410T patent/PT1490363E/pt unknown
- 2003-03-17 EP EP03708410A patent/EP1490363B1/de not_active Expired - Lifetime
- 2003-03-17 DE DE60303363T patent/DE60303363T2/de not_active Expired - Lifetime
- 2003-03-17 AU AU2003212585A patent/AU2003212585B2/en not_active Ceased
- 2003-03-17 RU RU2004131835/04A patent/RU2318823C2/ru not_active IP Right Cessation
- 2003-03-17 NZ NZ535685A patent/NZ535685A/en not_active IP Right Cessation
- 2003-03-17 IL IL16437703A patent/IL164377A0/xx unknown
- 2003-03-17 WO PCT/IB2003/001141 patent/WO2003082870A1/en active IP Right Grant
- 2003-03-17 JP JP2003580335A patent/JP4471664B2/ja not_active Expired - Fee Related
- 2003-03-17 ES ES03708410T patent/ES2256723T3/es not_active Expired - Lifetime
- 2003-03-17 CA CA2480776A patent/CA2480776C/en not_active Expired - Fee Related
- 2003-03-17 AT AT03708410T patent/ATE316530T1/de active
- 2003-03-24 TW TW092106529A patent/TWI237639B/zh not_active IP Right Cessation
- 2003-03-27 AR ARP030101080A patent/AR039169A1/es not_active Application Discontinuation
- 2003-03-27 US US10/400,780 patent/US6949653B2/en not_active Expired - Lifetime
2004
- 2004-10-03 IL IL164377A patent/IL164377A/en not_active IP Right Cessation
2005
- 2005-08-18 US US11/206,144 patent/US7057047B2/en not_active Expired - Lifetime
2006
- 2006-04-13 CY CY20061100511T patent/CY1105785T1/el unknown
- 2006-04-27 US US11/411,952 patent/US7304158B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IL164377A (en)	2011-07-31
EP1490363A1 (de)	2004-12-29
WO2003082870A1 (en)	2003-10-09
DE60303363T2 (de)	2006-10-12
US20060194830A1 (en)	2006-08-31
TW200305406A (en)	2003-11-01
US7304158B2 (en)	2007-12-04
AU2003212585B2 (en)	2009-02-26
CA2480776C (en)	2010-11-23
JP4471664B2 (ja)	2010-06-02
US20030191315A1 (en)	2003-10-09
US6949653B2 (en)	2005-09-27
RU2004131835A (ru)	2005-07-10
EP1490363B1 (de)	2006-01-25
AR039169A1 (es)	2005-02-09
DK1490363T3 (da)	2006-05-15
IL164377A0 (en)	2005-12-18
AU2003212585A1 (en)	2003-10-13
DE60303363D1 (de)	2006-04-13
RU2318823C2 (ru)	2008-03-10
NZ535685A (en)	2007-04-27
ES2256723T3 (es)	2006-07-16
CY1105785T1 (el)	2011-02-02
PT1490363E (pt)	2006-06-30
TWI237639B (en)	2005-08-11
US7057047B2 (en)	2006-06-06
CA2480776A1 (en)	2003-10-09
US20050288322A1 (en)	2005-12-29
JP2005528369A (ja)	2005-09-22

Legal Events

Date

Code

Title

Description

2006-12-15

UEP

Publication of translation of european patent specification

Ref document number: 1490363

Country of ref document: EP

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