ATE307803T1 - Herstellung von 3-amino-2-chlor-4-methylpyridin aus aceton und ethylcyanoacetat - Google Patents
Herstellung von 3-amino-2-chlor-4-methylpyridin aus aceton und ethylcyanoacetatInfo
- Publication number
- ATE307803T1 ATE307803T1 AT00903131T AT00903131T ATE307803T1 AT E307803 T1 ATE307803 T1 AT E307803T1 AT 00903131 T AT00903131 T AT 00903131T AT 00903131 T AT00903131 T AT 00903131T AT E307803 T1 ATE307803 T1 AT E307803T1
- Authority
- AT
- Austria
- Prior art keywords
- methylpyridine
- acetone
- amino
- ethylcyanoacetate
- chlorine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11670399P | 1999-01-22 | 1999-01-22 | |
PCT/US2000/000261 WO2000043364A1 (en) | 1999-01-22 | 2000-01-06 | Synthesis of 3-amino-2-chloro-4-methylpyridine from acetone and ethyl cyanoacetate |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE307803T1 true ATE307803T1 (de) | 2005-11-15 |
Family
ID=22368723
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00903131T ATE307803T1 (de) | 1999-01-22 | 2000-01-06 | Herstellung von 3-amino-2-chlor-4-methylpyridin aus aceton und ethylcyanoacetat |
Country Status (8)
Country | Link |
---|---|
US (1) | US6136982A (de) |
EP (1) | EP1070053B1 (de) |
JP (1) | JP2002535310A (de) |
AT (1) | ATE307803T1 (de) |
CA (1) | CA2318412A1 (de) |
DE (1) | DE60023402T2 (de) |
ES (1) | ES2251964T3 (de) |
WO (1) | WO2000043364A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6399781B1 (en) | 2000-10-10 | 2002-06-04 | Boehringer Ingelheim Chemicals, Inc. | Process for making 3-amino-2-chloro-4-methylpyridine |
CN100358871C (zh) * | 2005-08-02 | 2008-01-02 | 江阴暨阳医药化工有限公司 | 氰乙酰胺和丙酮合成2-氯-3-氨基-4-甲基吡啶法 |
CA2802831C (en) | 2010-06-16 | 2018-11-20 | Teijin Pharma Limited | Controlled release coat-core tablet |
WO2016118586A1 (en) * | 2015-01-20 | 2016-07-28 | Virginia Commonwealth University | Lowcost, high yield synthesis of nevirapine |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2082801C (en) * | 1991-06-11 | 2003-07-08 | Karl G. Grozinger | Method for the preparation of 3-amino-2-chloro-4-alkylpyridines |
US5654429A (en) * | 1992-11-18 | 1997-08-05 | Boehringer Ingelheim Pharma | Method for the preparation of 3-amino-2-chloro-4-alkylpyridines |
DE59409324D1 (de) * | 1993-12-02 | 2000-06-08 | Boehringer Ingelheim Pharma | Verfahren zur herstellung von 3-amino-2-chlor-4-alkyl- bzw. 4-cycloalkyl-pyridine |
-
2000
- 2000-01-06 CA CA002318412A patent/CA2318412A1/en not_active Abandoned
- 2000-01-06 ES ES00903131T patent/ES2251964T3/es not_active Expired - Lifetime
- 2000-01-06 US US09/478,588 patent/US6136982A/en not_active Expired - Lifetime
- 2000-01-06 DE DE60023402T patent/DE60023402T2/de not_active Expired - Fee Related
- 2000-01-06 AT AT00903131T patent/ATE307803T1/de not_active IP Right Cessation
- 2000-01-06 JP JP2000594780A patent/JP2002535310A/ja not_active Ceased
- 2000-01-06 WO PCT/US2000/000261 patent/WO2000043364A1/en active IP Right Grant
- 2000-01-06 EP EP00903131A patent/EP1070053B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE60023402D1 (de) | 2005-12-01 |
CA2318412A1 (en) | 2000-07-27 |
EP1070053A1 (de) | 2001-01-24 |
WO2000043364A1 (en) | 2000-07-27 |
EP1070053A4 (de) | 2001-04-18 |
US6136982A (en) | 2000-10-24 |
DE60023402T2 (de) | 2006-04-27 |
ES2251964T3 (es) | 2006-05-16 |
JP2002535310A (ja) | 2002-10-22 |
EP1070053B1 (de) | 2005-10-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1070053 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |