ATE302747T1 - Verfahren zur herstellung von amphetaminen aus phenylpropanolaminen - Google Patents

Verfahren zur herstellung von amphetaminen aus phenylpropanolaminen

Info

Publication number
ATE302747T1
ATE302747T1 AT02802245T AT02802245T ATE302747T1 AT E302747 T1 ATE302747 T1 AT E302747T1 AT 02802245 T AT02802245 T AT 02802245T AT 02802245 T AT02802245 T AT 02802245T AT E302747 T1 ATE302747 T1 AT E302747T1
Authority
AT
Austria
Prior art keywords
formula
alkyl group
group
lower alkyl
phenylpropanolamine salt
Prior art date
Application number
AT02802245T
Other languages
English (en)
Inventor
Robert F Boswell
Young S Lo
Original Assignee
Boehringer Ingelheim Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Chemicals filed Critical Boehringer Ingelheim Chemicals
Application granted granted Critical
Publication of ATE302747T1 publication Critical patent/ATE302747T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT02802245T 2001-10-29 2002-10-28 Verfahren zur herstellung von amphetaminen aus phenylpropanolaminen ATE302747T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/020,488 US6399828B1 (en) 2001-10-29 2001-10-29 Preparation of amphetamines from phenylpropanolamines
PCT/US2002/034400 WO2003037843A2 (en) 2001-10-29 2002-10-28 Preparation of amphetamines from phenylpropanolamines

Publications (1)

Publication Number Publication Date
ATE302747T1 true ATE302747T1 (de) 2005-09-15

Family

ID=21798883

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02802245T ATE302747T1 (de) 2001-10-29 2002-10-28 Verfahren zur herstellung von amphetaminen aus phenylpropanolaminen

Country Status (11)

Country Link
US (1) US6399828B1 (de)
EP (1) EP1442006B1 (de)
JP (1) JP2005507936A (de)
AT (1) ATE302747T1 (de)
AU (1) AU2002356860A1 (de)
CA (1) CA2462916A1 (de)
DE (1) DE60205769T2 (de)
DK (1) DK1442006T3 (de)
ES (1) ES2248640T3 (de)
PT (1) PT1442006E (de)
WO (1) WO2003037843A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1644019T4 (en) * 2003-05-29 2018-04-23 Shire Llc AMPHETAMINE COMPOUNDS RESISTANT TO ABUSE
ATE407112T1 (de) * 2004-12-22 2008-09-15 Emmellen Biotech Pharmaceutica Verfahren zur herstellung von r-(-)-n, alpha- dimethylphenethylamin (levmetamphetamin) oder s- (+)-n, alpha-dimethylphenethylamin (metamphetamin) aus d-ephedrin bzw. l-ephedrin
EP1838658A1 (de) * 2005-01-06 2007-10-03 Mallinckrodt, Inc. Verfahren zur herstellung benzylierter amine
TWI401237B (zh) * 2006-07-24 2013-07-11 ３-〔（１ｒ，２ｒ）-３-（二甲基氨基）-１-乙基-２-甲基丙基〕酚之製備
US7705184B2 (en) * 2008-05-20 2010-04-27 Cambrex Charles City, Inc. Method of making amphetamine
US20100125146A1 (en) * 2008-11-19 2010-05-20 Johnson Matthey Public Limited Company Method for making pharmaceutical compounds
WO2010148305A1 (en) * 2009-06-19 2010-12-23 Cambrex Charles City, Inc. Methods and compositions for preparation of amphetamine conjugates and salts thereof
JP5094832B2 (ja) * 2009-12-25 2012-12-12 日東電工株式会社 粘着剤組成物および粘着シート
JP5657913B2 (ja) * 2010-05-10 2015-01-21 中部電力株式会社 ナノコンポジット半導体光触媒材料とメタノール水溶液を用いた水素製造手法
US8779191B2 (en) 2010-12-20 2014-07-15 Cambrex Charles City, Inc. Methods and compositions for preparing lisdexamfetamine and salts thereof
US11123310B2 (en) 2017-02-24 2021-09-21 Pharmapotheca, Llc Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms
US9321794B2 (en) 2013-12-31 2016-04-26 Chemapotheca, Llc Synthesis of racemic amphetamine derivatives by cuprate addition reaction with aziridine phosphoramidate compounds
US9278904B2 (en) 2013-12-31 2016-03-08 Chemapotheca, Llc Synthesis of chiral amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds
US10544434B2 (en) 2015-06-29 2020-01-28 Noramco, Inc. Process for the preparation of lisdexamfetamine and related derivatives
IL288554B2 (en) 2016-02-24 2024-02-01 Chemapotheca LLC Controlled release of amphetamine, drug meters and dosage forms with abuse deterrence
US11590081B1 (en) 2017-09-24 2023-02-28 Tris Pharma, Inc Extended release amphetamine tablets
CA3131403A1 (en) 2019-03-02 2020-09-10 Chemapotheca, Llc Process for making levoamphetamine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2802828A (en) * 1957-08-13 New derivatives of hydroxylated
DE2817494A1 (de) * 1977-05-03 1978-11-09 Continental Pharma Aminoalkohol-derivat
DE19859684A1 (de) * 1998-12-23 2000-06-29 Bayer Ag Verfahren zur Herstellung von Fluor enthaltenden Phenethylaminen sowie neue, Fluor enthalende beta-Iminovinyl- und beta-Iminoethylbenzole

Also Published As

Publication number Publication date
DE60205769D1 (de) 2005-09-29
ES2248640T3 (es) 2006-03-16
WO2003037843A2 (en) 2003-05-08
US6399828B1 (en) 2002-06-04
EP1442006B1 (de) 2005-08-24
WO2003037843A3 (en) 2003-10-30
JP2005507936A (ja) 2005-03-24
PT1442006E (pt) 2005-11-30
DE60205769T2 (de) 2006-06-08
EP1442006A2 (de) 2004-08-04
CA2462916A1 (en) 2003-05-08
AU2002356860A1 (en) 2003-05-12
DK1442006T3 (da) 2005-12-12

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