ATE293494T1 - Verfahren zum konzentrieren von analyten in proben - Google Patents

Verfahren zum konzentrieren von analyten in proben

Info

Publication number
ATE293494T1
ATE293494T1 AT01998402T AT01998402T ATE293494T1 AT E293494 T1 ATE293494 T1 AT E293494T1 AT 01998402 T AT01998402 T AT 01998402T AT 01998402 T AT01998402 T AT 01998402T AT E293494 T1 ATE293494 T1 AT E293494T1
Authority
AT
Austria
Prior art keywords
container
analyte
sample
present
solution
Prior art date
Application number
AT01998402T
Other languages
English (en)
Inventor
Pierre Puget
Patrick Pouteau
Frederic Ginot
Patrice Caillat
Original Assignee
Commissariat Energie Atomique
Biomerieux Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique, Biomerieux Sa filed Critical Commissariat Energie Atomique
Application granted granted Critical
Publication of ATE293494T1 publication Critical patent/ATE293494T1/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/005Pretreatment specially adapted for magnetic separation
    • B03C1/01Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/025High gradient magnetic separators
    • B03C1/031Component parts; Auxiliary operations
    • B03C1/033Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0332Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/28Magnetic plugs and dipsticks
    • B03C1/288Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/18Magnetic separation whereby the particles are suspended in a liquid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/26Details of magnetic or electrostatic separation for use in medical applications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Fluid Mechanics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
AT01998402T 2000-11-29 2001-11-27 Verfahren zum konzentrieren von analyten in proben ATE293494T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0015417A FR2817343B1 (fr) 2000-11-29 2000-11-29 Procede et dispositifs de transport et de concentration d'un analyte present dans un echantillon
PCT/FR2001/003743 WO2002043865A1 (fr) 2000-11-29 2001-11-27 Procedes et dispositifs de transport et de concentration d'un analyte present dans un echantillon

Publications (1)

Publication Number Publication Date
ATE293494T1 true ATE293494T1 (de) 2005-05-15

Family

ID=8857009

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01998402T ATE293494T1 (de) 2000-11-29 2001-11-27 Verfahren zum konzentrieren von analyten in proben

Country Status (7)

Country Link
US (1) US7569398B2 (de)
EP (1) EP1343586B1 (de)
AT (1) ATE293494T1 (de)
AU (1) AU2002222057A1 (de)
DE (1) DE60110256T2 (de)
FR (1) FR2817343B1 (de)
WO (1) WO2002043865A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078224B1 (en) * 1999-05-14 2006-07-18 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
JP4633627B2 (ja) * 2003-07-16 2011-02-16 東洋紡績株式会社 生体成分分離用デバイス、およびそれを用いた生体成分の分離方法
DE10354351B3 (de) * 2003-11-20 2005-06-16 november Aktiengesellschaft Gesellschaft für Molekulare Medizin Verfahren und Vorrichtung zur verbesserten Reinigung einer an paramagnetische Mikropartikel gebundenen Substanz
FR2863626B1 (fr) * 2003-12-15 2006-08-04 Commissariat Energie Atomique Procede et dispositif de division d'un echantillon biologique par effet magnetique
DE102004005193B4 (de) * 2004-02-02 2006-08-24 Medion Diagnostics Gmbh Vorrichtung zur Separation einzelner Partikel von Partikel-Agglutinationen
JP2006053090A (ja) * 2004-08-13 2006-02-23 Alps Electric Co Ltd 検査用プレートと、前記検査用プレートを用いた検査方法
US8623668B2 (en) * 2004-11-05 2014-01-07 Imec Method for transport of magnetic particles and devices therefor
US7502625B2 (en) * 2005-01-20 2009-03-10 Skyworks Solutions, Inc. Integrated multi-band transceiver for use in mobile communication device
JP2009500019A (ja) * 2005-07-01 2009-01-08 プロメガ・コーポレーション 生体分子の精製のための浮遊性粒子のネットワーク、及び生体分子の精製のための浮遊性粒子又は浮遊性粒子のネットワークの使用
DE102005039175A1 (de) * 2005-08-18 2007-02-22 Qiagen Gmbh Vorrichtung und Verfahren zum Abtrennen von magnetischen Partikeln aus einer Flüssigkeit
EP1963526A4 (de) * 2005-12-09 2009-11-18 Promega Corp Nukleinsäurereinigung mittels bindungsmatrix
EP1979751A1 (de) 2006-01-25 2008-10-15 Koninklijke Philips Electronics N.V. Vorrichtung zur analyse von fluiden
CN101495868A (zh) * 2006-07-28 2009-07-29 博适公司 利用磁性颗粒进行受体结合试验的装置和方法
EP1939629A3 (de) * 2006-08-11 2011-03-09 Samsung Electronics Co., Ltd. Vorrichtung zur zentrifugalkraftbasierten Magnetpositionssteuerung sowie scheibenförmiges Mikrofluidiksystem
EP2384432B1 (de) 2007-06-21 2016-12-28 Gen-Probe Incorporated Instrument und behälter zur durchführung von verfahren
MX2010002079A (es) * 2007-08-24 2010-08-09 Advanced Liquid Logic Inc Manipulacion de esferas en un inyector de gotas.
WO2009038536A1 (en) * 2007-09-19 2009-03-26 Agency For Science, Technology And Research A device, system and method for washing and isolating magnetic particles in a continous fluid flow
EP2072133A1 (de) * 2007-12-20 2009-06-24 Koninklijke Philips Electronics N.V. Mehrkammervorrichtung mit magnetischen Partikeln
WO2009091320A1 (en) * 2008-01-17 2009-07-23 Ge Healthcare Bio-Sciences Ab Method for sample application
US8222397B2 (en) * 2009-08-28 2012-07-17 Promega Corporation Methods of optimal purification of nucleic acids and kit for use in performing such methods
US8039613B2 (en) 2009-08-28 2011-10-18 Promega Corporation Methods of purifying a nucleic acid and formulation and kit for use in performing such methods
CN106771219B (zh) 2010-06-17 2020-04-07 皇家飞利浦电子股份有限公司 多表位测定
JP6382699B2 (ja) * 2014-11-28 2018-08-29 株式会社東芝 マイクロ分析チップ
CN105424922B (zh) * 2015-12-09 2018-01-19 北京乐普医疗科技有限责任公司 基于磁珠包被抗体的微流控芯片及捕获心肌标志物的方法
EP3501658B1 (de) * 2019-03-19 2021-04-21 Ace Medical Technology Co., Ltd. Vorrichtung zum sortieren von biopartikeln unter verwendung einer mittels lichtinduzierter dielektrophorese erzeugten kraft und verfahren dafür

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498392A (en) * 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
WO1994026414A1 (en) 1993-05-17 1994-11-24 Syntex (U.S.A.) Inc. Reaction container for specific binding assays and method for its use
US5603760A (en) * 1995-09-18 1997-02-18 W. R. Grace & Co.-Conn. Cement admixture capable of inhibiting drying shrinkage and method of using same
US5863502A (en) * 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
US6074827A (en) * 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
DK0925494T3 (da) * 1996-09-04 2002-07-01 Scandinavian Micro Biodevices Mikrostrømningssystem til partikelseparation og analyse
FR2758884B1 (fr) * 1997-01-30 1999-04-02 Bio Merieux Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu
ATE469699T1 (de) * 1999-02-23 2010-06-15 Caliper Life Sciences Inc Manipulation von mikroteilchen in mikrofluiden systemen

Also Published As

Publication number Publication date
EP1343586B1 (de) 2005-04-20
EP1343586A1 (de) 2003-09-17
US7569398B2 (en) 2009-08-04
US20040023273A1 (en) 2004-02-05
FR2817343B1 (fr) 2003-05-09
FR2817343A1 (fr) 2002-05-31
DE60110256T2 (de) 2006-03-09
WO2002043865A1 (fr) 2002-06-06
DE60110256D1 (de) 2005-05-25
AU2002222057A1 (en) 2002-06-11

Similar Documents

Publication Publication Date Title
ATE293494T1 (de) Verfahren zum konzentrieren von analyten in proben
ATE321891T1 (de) Vorrichtung und verfahren zur durchführung und überprüfung von biologischen prozessen
ATE539816T1 (de) Verfahren zum diagnostischen testen
ATE137024T1 (de) Verfahren und magnetische vorrichtung zur immunologischen analyse von festphasen
ATE181517T1 (de) Vorrichtung und verfahren zur dosierung von flüssigkeitsproben
ATE431553T1 (de) Verfahren zum nachweis von analyten durch magnetischen teilchen
DE69902676D1 (de) Assay unter verwendung von porositätsverminderung zur verhinderung von migration
DE69918135D1 (de) Verfahren zum durchführen von tests
DK1093393T3 (da) Fremgangsmåde og apparat til magnetisk separering af udvalgte partikler, navnlig biologiske celler
DE19882221T1 (de) Verfahren und Vorrichtung zum automatischen Impfen von Kulturmedien mit bakteriellen Proben aus klinischen Probenbehältern
TW348216B (en) Method for the determination of urinary protein and creatinine
ATE337855T1 (de) Verfahren und vorrichtung zur vorbehandlung von proben durch zentrifugieren
WO2004011607A3 (en) Reagent and method for determination of a substance using an immunoaggregator
GB9709821D0 (en) Allergy assay
ATE339687T1 (de) Immunologische verfahren, vorrichtungen und reagenzien
DE68923605T2 (de) Immunodiagnostisches Verfahren zum Nachweis und zur Bestimmung von Euterentzündung.
DE60028976D1 (de) Analytisches verfahren und vorrichtung
FR2764703B1 (fr) Procede pour l'analyse automatique en continu ou en discontinu d'echantillons contenus dans des recipients
DE59606129D1 (de) Verfahren und verbindungen zur detektion von analyten mittels remanenzmessung und deren verwendung
EP0399464A3 (de) Testverfahren für eine Substanz mit einer spezifischen Zuckerkette
SE9502024D0 (sv) Pathogen assay method
DE60143531D1 (de) Vorrichtung, verfahren und verwendung zur behandlung von proben
CA2520438A1 (en) Latex reagent for adiponectin analysis and method of adiponectin analysis
SE8801011L (sv) Foerfarande foer bestaemning av koncentrationen av en luminiscerande
DE69428998T2 (de) Reagenzien und verfahren zur detektion und quantitativen bestimmung von testosteron in flüssigen proben

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties