ATE293160T1 - Nicht-embryonale ependymale neuronale stammzellen und methoden zu ihrer isolierung - Google Patents
Nicht-embryonale ependymale neuronale stammzellen und methoden zu ihrer isolierungInfo
- Publication number
- ATE293160T1 ATE293160T1 AT99933396T AT99933396T ATE293160T1 AT E293160 T1 ATE293160 T1 AT E293160T1 AT 99933396 T AT99933396 T AT 99933396T AT 99933396 T AT99933396 T AT 99933396T AT E293160 T1 ATE293160 T1 AT E293160T1
- Authority
- AT
- Austria
- Prior art keywords
- ependymal
- stem cells
- notch
- embryonal
- isolation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Developmental Biology & Embryology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9802264A SE9802264D0 (sv) | 1998-06-25 | 1998-06-25 | A method of isolating cells |
PCT/SE1999/001157 WO1999067363A1 (en) | 1998-06-25 | 1999-06-24 | Ependymal neural stem cells and method for their isolation |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE293160T1 true ATE293160T1 (de) | 2005-04-15 |
Family
ID=20411839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99933396T ATE293160T1 (de) | 1998-06-25 | 1999-06-24 | Nicht-embryonale ependymale neuronale stammzellen und methoden zu ihrer isolierung |
Country Status (14)
Country | Link |
---|---|
US (1) | US7320872B2 (de) |
EP (1) | EP1090105B1 (de) |
JP (1) | JP2002518043A (de) |
KR (1) | KR20010071601A (de) |
CN (1) | CN1325637C (de) |
AT (1) | ATE293160T1 (de) |
AU (1) | AU770501B2 (de) |
BR (1) | BR9911509A (de) |
CA (1) | CA2330175A1 (de) |
DE (1) | DE69924728T2 (de) |
ES (1) | ES2241297T3 (de) |
MX (1) | MXPA00012078A (de) |
SE (1) | SE9802264D0 (de) |
WO (1) | WO1999067363A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6541247B1 (en) * | 1998-06-25 | 2003-04-01 | Neuronova Ab | Method of isolating ependymal neural stem cells |
WO2001078752A2 (en) * | 2000-04-13 | 2001-10-25 | Board Of Regents, The University Of Texas System | Treatment of disorders by implanting stem cells and/or progeny thereof into gastrointestinal organs |
GB0013260D0 (en) * | 2000-05-31 | 2000-07-19 | Neuronova Ab | Method |
US20030036195A1 (en) * | 2001-04-20 | 2003-02-20 | Lorenz Studer | Generation of differentiated tissue from nuclear transfer embryonic stem cells and methods of use |
US20060128014A1 (en) * | 2002-08-26 | 2006-06-15 | Johan Haggblad | Compositions and methods for culturing stem cells |
US20090191173A1 (en) * | 2004-11-29 | 2009-07-30 | Michal Eisenbach-Schwartz | Induction Of Neurogenesis And Stem Cell Therapy In Combination With Copolymer 1 |
US20100015615A1 (en) * | 2008-04-30 | 2010-01-21 | Sloan-Kettering Institute For Cancer Research | Identification and Isolation of Adult Stem Cells and Related Methods of Use |
US8962314B2 (en) | 2008-11-26 | 2015-02-24 | The Regents Of The University Of California | Lateral ventricle cell compositions and use for treating neural degenerative diseases |
BR112012001329B1 (pt) * | 2009-07-21 | 2021-04-13 | Abt Holding Company | Uso de células progenitoras adultas multipotentes (mapcs), e, métodos para obter células progenitoras adultas multipotentes (mapcs) com uma potência desejada e para aumentar a potência de células progenitoras adultas multipotentes (mapcs) |
ES2402308B2 (es) * | 2011-09-27 | 2013-12-27 | Universidad De Málaga | Procedimiento de obtención de un cultivo puro de células ependimarias multiciliadas. |
US11730767B2 (en) * | 2018-02-23 | 2023-08-22 | Regeneration Biomedical, Inc. | Methods, apparatuses and systems for instilling stem cells and pharmaceuticals into the human ventricular system |
CN111440768B (zh) * | 2020-04-23 | 2022-09-02 | 青岛海尔生物科技有限公司 | 重组人Notch1蛋白在制备神经干细胞及皮层神经元中的应用 |
CN113777296A (zh) * | 2021-09-16 | 2021-12-10 | 复旦大学附属中山医院 | 一种全量组织免疫荧光方法和应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5851832A (en) * | 1991-07-08 | 1998-12-22 | Neurospheres, Ltd. | In vitro growth and proliferation of multipotent neural stem cells and their progeny |
CA2140884A1 (en) * | 1992-07-27 | 1994-02-03 | David J. Anderson | Mammalian multipotent neural stem cells |
AU697894B2 (en) * | 1993-11-09 | 1998-10-22 | Neurospheres Holdings Ltd | (In situ) modification and manipulation of stem cells of the central nervous system |
CN1161744A (zh) * | 1994-09-23 | 1997-10-08 | 纽罗斯菲里斯控股有限公司 | 中枢神经***(cns)功能和机能障碍的体外模型 |
US5753505A (en) * | 1995-07-06 | 1998-05-19 | Emory University | Neuronal progenitor cells and uses thereof |
US5800812A (en) | 1995-09-15 | 1998-09-01 | Yeda Research And Development Co. Ltd. | Methods of use of mononuclear phagocytes to promote axonal regeneration |
US5780300A (en) * | 1995-09-29 | 1998-07-14 | Yale University | Manipulation of non-terminally differentiated cells using the notch pathway |
US5753506A (en) * | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
US6093531A (en) * | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
US6541247B1 (en) * | 1998-06-25 | 2003-04-01 | Neuronova Ab | Method of isolating ependymal neural stem cells |
-
1998
- 1998-06-25 SE SE9802264A patent/SE9802264D0/xx unknown
-
1999
- 1999-06-24 KR KR1020007014792A patent/KR20010071601A/ko not_active Application Discontinuation
- 1999-06-24 EP EP99933396A patent/EP1090105B1/de not_active Expired - Lifetime
- 1999-06-24 ES ES99933396T patent/ES2241297T3/es not_active Expired - Lifetime
- 1999-06-24 BR BR9911509-3A patent/BR9911509A/pt not_active IP Right Cessation
- 1999-06-24 DE DE69924728T patent/DE69924728T2/de not_active Expired - Lifetime
- 1999-06-24 JP JP2000556008A patent/JP2002518043A/ja active Pending
- 1999-06-24 MX MXPA00012078A patent/MXPA00012078A/es not_active IP Right Cessation
- 1999-06-24 CA CA002330175A patent/CA2330175A1/en not_active Abandoned
- 1999-06-24 WO PCT/SE1999/001157 patent/WO1999067363A1/en active IP Right Grant
- 1999-06-24 CN CNB998078697A patent/CN1325637C/zh not_active Expired - Fee Related
- 1999-06-24 AU AU49459/99A patent/AU770501B2/en not_active Ceased
- 1999-06-24 AT AT99933396T patent/ATE293160T1/de active
-
2002
- 2002-06-27 US US10/183,728 patent/US7320872B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69924728D1 (de) | 2005-05-19 |
CA2330175A1 (en) | 1999-12-29 |
MXPA00012078A (es) | 2005-06-20 |
WO1999067363A9 (en) | 2000-03-16 |
KR20010071601A (ko) | 2001-07-28 |
CN1325637C (zh) | 2007-07-11 |
AU4945999A (en) | 2000-01-10 |
EP1090105B1 (de) | 2005-04-13 |
EP1090105A1 (de) | 2001-04-11 |
AU770501B2 (en) | 2004-02-26 |
ES2241297T3 (es) | 2005-10-16 |
WO1999067363A1 (en) | 1999-12-29 |
BR9911509A (pt) | 2001-03-20 |
DE69924728T2 (de) | 2006-03-09 |
JP2002518043A (ja) | 2002-06-25 |
US20030092176A1 (en) | 2003-05-15 |
CN1307632A (zh) | 2001-08-08 |
US7320872B2 (en) | 2008-01-22 |
SE9802264D0 (sv) | 1998-06-25 |
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