ATE292175T1 - Dna kodierend für den menschlichen 5-ht 1e- rezeptor und seine verwendungen - Google Patents

Dna kodierend für den menschlichen 5-ht 1e- rezeptor und seine verwendungen

Info

Publication number
ATE292175T1
ATE292175T1 AT93900769T AT93900769T ATE292175T1 AT E292175 T1 ATE292175 T1 AT E292175T1 AT 93900769 T AT93900769 T AT 93900769T AT 93900769 T AT93900769 T AT 93900769T AT E292175 T1 ATE292175 T1 AT E292175T1
Authority
AT
Austria
Prior art keywords
human
ht1e
receptor
nucleic acid
receptors
Prior art date
Application number
AT93900769T
Other languages
English (en)
Inventor
Richard L Weinshank
Theresa Branchek
Paul R Hartig
Original Assignee
Synaptic Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synaptic Pharma Corp filed Critical Synaptic Pharma Corp
Application granted granted Critical
Publication of ATE292175T1 publication Critical patent/ATE292175T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6425Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
AT93900769T 1991-12-02 1992-12-02 Dna kodierend für den menschlichen 5-ht 1e- rezeptor und seine verwendungen ATE292175T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80362691A 1991-12-02 1991-12-02
PCT/US1992/010377 WO1993011147A1 (en) 1991-12-02 1992-12-02 Dna encoding a human 5-ht1e receptor and uses thereof

Publications (1)

Publication Number Publication Date
ATE292175T1 true ATE292175T1 (de) 2005-04-15

Family

ID=25187041

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93900769T ATE292175T1 (de) 1991-12-02 1992-12-02 Dna kodierend für den menschlichen 5-ht 1e- rezeptor und seine verwendungen

Country Status (10)

Country Link
US (3) US5476782A (de)
EP (1) EP0585415B1 (de)
JP (1) JPH06508764A (de)
AT (1) ATE292175T1 (de)
AU (1) AU672768B2 (de)
CA (1) CA2101162A1 (de)
DE (2) DE585415T1 (de)
ES (1) ES2085246T1 (de)
GR (1) GR960300015T1 (de)
WO (1) WO1993011147A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5661024A (en) * 1989-10-31 1997-08-26 Synaptic Pharmaceutical Corporation DNA encoding a human serotonic (5-HT2) receptor and uses thereof
US5935925A (en) * 1990-05-08 1999-08-10 Synaptic Pharmaceutical Corporation Methods of treating migraine and compounds useful for such methods
US5155218A (en) 1990-05-08 1992-10-13 Neurogenetic Corporation Dna encoding human 5-ht1d receptors
ATE292175T1 (de) * 1991-12-02 2005-04-15 Synaptic Pharma Corp Dna kodierend für den menschlichen 5-ht 1e- rezeptor und seine verwendungen
US6406859B1 (en) 1992-01-08 2002-06-18 Synaptic Pharmaceutical Corporation DNA encoding a 5-HT 1F receptor and uses thereof
US5360735A (en) * 1992-01-08 1994-11-01 Synaptic Pharmaceutical Corporation DNA encoding a human 5-HT1F receptor, vectors, and host cells
US6300087B1 (en) 1992-11-03 2001-10-09 Synaptic Pharmaceutical Corporation DNA encoding a human serotonin receptor (5-HT4B) and uses thereof
WO1994009828A1 (en) * 1992-11-03 1994-05-11 Synaptic Pharmaceutical Corporation Dna encoding a human serotonin receptor (5-ht4b) and uses thereof
US5472866A (en) 1992-12-24 1995-12-05 Synaptic Pharmaceutical Corporation DNA encoding 5-HT4A serotonin receptors
US20020115149A1 (en) * 1993-01-08 2002-08-22 Synaptic Pharmaceutical Corporation DNA encoding human 5-HT1D receptors and uses thereof
EP0665887B1 (de) * 1993-08-20 1998-10-14 Smithkline Beecham Plc Humane 5-ht2 rezeptor
US5698766A (en) * 1995-04-05 1997-12-16 The Regents Of The University Of California Transgenic animal model for testing drugs for treating eating disorders and epilepsy
US6221660B1 (en) 1999-02-22 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding SNORF25 receptor
US20070042433A1 (en) * 2003-03-26 2007-02-22 Jianxin Bao Neuregulin protein regulation of synaptic proteins
US20070270339A1 (en) * 2004-04-23 2007-11-22 Serono, Inc. Use of GPCR54 Ligands for the Treatment of Infertility
DE102004026744A1 (de) * 2004-05-28 2005-12-29 Philipps-Universität Marburg Erfindung betreffend cDNA-Herstellung aus Zellen nach Laser-Mikrodissektion
EP1765083A4 (de) * 2004-05-28 2008-08-20 Serono Lab Verwendung von il-17 bei der behandlung von fruchtbarkeitsstörungen
JP4286877B2 (ja) * 2007-03-13 2009-07-01 Okiセミコンダクタ株式会社 炭化珪素半導体装置およびその製造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675285A (en) * 1984-09-19 1987-06-23 Genetics Institute, Inc. Method for identification and isolation of DNA encoding a desired protein
US4904582A (en) * 1987-06-11 1990-02-27 Synthetic Genetics Novel amphiphilic nucleic acid conjugates
US4985352A (en) * 1988-02-29 1991-01-15 The Trustees Of Columbia University In The City Of New York DNA encoding serotonin 1C (5HT1c) receptor, isolated 5HT1c receptor, mammalian cells expressing same and uses thereof
FR2628750B1 (fr) * 1988-03-21 1991-11-08 Pasteur Institut Vecteur modifie par une sequence codant pour une sequence d'acides amines contenue dans une proteine de mammifere ayant une activite biologique de recepteur membranaire
US5155218A (en) * 1990-05-08 1992-10-13 Neurogenetic Corporation Dna encoding human 5-ht1d receptors
ATE292175T1 (de) * 1991-12-02 2005-04-15 Synaptic Pharma Corp Dna kodierend für den menschlichen 5-ht 1e- rezeptor und seine verwendungen
US5360735A (en) * 1992-01-08 1994-11-01 Synaptic Pharmaceutical Corporation DNA encoding a human 5-HT1F receptor, vectors, and host cells
GB2267906A (en) * 1992-06-11 1993-12-22 Merck Sharp & Dohme Human brain serotonin receptor
US5472866A (en) * 1992-12-24 1995-12-05 Synaptic Pharmaceutical Corporation DNA encoding 5-HT4A serotonin receptors

Also Published As

Publication number Publication date
JPH06508764A (ja) 1994-10-06
GR960300015T1 (de) 1996-03-31
AU3233893A (en) 1993-06-28
AU672768B2 (en) 1996-10-17
US5786155A (en) 1998-07-28
US5476782A (en) 1995-12-19
CA2101162A1 (en) 1993-06-03
US6096507A (en) 2000-08-01
EP0585415A1 (de) 1994-03-09
DE69233496D1 (de) 2005-05-04
EP0585415A4 (de) 1994-04-13
WO1993011147A1 (en) 1993-06-10
EP0585415B1 (de) 2005-03-30
DE585415T1 (de) 1996-10-10
ES2085246T1 (es) 1996-06-01

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties