ATE289508T1 - Butyrate derivaten zur behandlung von fibromyalgia und chronische müdigkeit-syndrom - Google Patents
Butyrate derivaten zur behandlung von fibromyalgia und chronische müdigkeit-syndromInfo
- Publication number
- ATE289508T1 ATE289508T1 AT98941094T AT98941094T ATE289508T1 AT E289508 T1 ATE289508 T1 AT E289508T1 AT 98941094 T AT98941094 T AT 98941094T AT 98941094 T AT98941094 T AT 98941094T AT E289508 T1 ATE289508 T1 AT E289508T1
- Authority
- AT
- Austria
- Prior art keywords
- fibromyalgia
- chronic fatigue
- treatment
- fatigue syndrome
- butyrate derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/920,979 US5990162A (en) | 1997-08-29 | 1997-08-29 | Method for treatment of fibromyalgia and chronic fatigue syndrome |
PCT/US1998/017818 WO1999009972A1 (en) | 1997-08-29 | 1998-08-27 | Butyrate derivatives in the treatment of fibromyalgia and chronic fatigue syndrome |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE289508T1 true ATE289508T1 (de) | 2005-03-15 |
Family
ID=25444733
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98941094T ATE289508T1 (de) | 1997-08-29 | 1998-08-27 | Butyrate derivaten zur behandlung von fibromyalgia und chronische müdigkeit-syndrom |
Country Status (15)
Country | Link |
---|---|
US (1) | US5990162A (de) |
EP (1) | EP1017381B1 (de) |
JP (1) | JP3660587B2 (de) |
AT (1) | ATE289508T1 (de) |
AU (1) | AU737086B2 (de) |
CA (1) | CA2301723C (de) |
CZ (1) | CZ295248B6 (de) |
DE (1) | DE69829112T2 (de) |
ES (1) | ES2235355T3 (de) |
HK (1) | HK1029278A1 (de) |
IL (2) | IL134669A0 (de) |
NO (1) | NO326479B1 (de) |
NZ (1) | NZ502983A (de) |
PT (1) | PT1017381E (de) |
WO (1) | WO1999009972A1 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1316309A1 (de) * | 1998-12-23 | 2003-06-04 | Orphan Medical Inc. | Mikrobenbeständige und stabilisierte Lösungen die gamma-Hydroxybuttersäuresalze zur Behandlung von Narkolepsie enthalten |
WO2000038672A2 (en) | 1998-12-23 | 2000-07-06 | Orphan Medical, Inc. | Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy |
US6610324B2 (en) * | 1999-04-07 | 2003-08-26 | The Mclean Hospital Corporation | Flupirtine in the treatment of fibromyalgia and related conditions |
ATE292965T1 (de) * | 1999-09-14 | 2005-04-15 | Tepha Inc | Therapeutische anwendung von polymere die gamma- hydroxybutyrat enthalten |
ES2383673T3 (es) | 2000-09-22 | 2012-06-25 | Jpi Commercial, Llc | Composiciones de gamma-hidroxibutirato que contienen portadores de hidrato de carbonos |
US7553829B2 (en) * | 2000-11-30 | 2009-06-30 | Humanetics Corporation | Treatment of chronic fatigue syndrome and fibromyalgia syndrome |
US20040259909A1 (en) * | 2001-10-16 | 2004-12-23 | Mccarthy Dennis | Treatment of fibromyalgia syndrome |
US20100324441A1 (en) * | 2002-02-04 | 2010-12-23 | Hargrove Jeffrey B | Brain-Related Chronic Pain Disorder Treatment Method and Apparatus |
US6703216B2 (en) | 2002-03-14 | 2004-03-09 | The Regents Of The University Of California | Methods, compositions and apparatuses for detection of gamma-hydroxybutyric acid (GHB) |
EP1638615B1 (de) | 2003-05-08 | 2014-10-29 | Tepha, Inc. | Medizinische polyhydroxyalkanoat-textilien und fasern |
DK1778305T3 (da) | 2004-08-03 | 2010-10-18 | Tepha Inc | Ikke-krøllende polyhydroxyalkanoatsuturer |
KR20070100686A (ko) * | 2004-09-07 | 2007-10-11 | 오르펀 메디칼, 인크. | 개선된 ghb 조성물 |
JP2008519847A (ja) * | 2004-11-10 | 2008-06-12 | ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク | 運動障害の治療方法 |
DE112006001234T5 (de) * | 2005-05-16 | 2008-04-10 | Johnson, Joseph, Knoxville | Verfahren und Zusammensetzung zur Behandlung von ARG |
US7838556B2 (en) * | 2006-02-21 | 2010-11-23 | University Of Maryland, Baltimore | Ethers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands |
US7943683B2 (en) | 2006-12-01 | 2011-05-17 | Tepha, Inc. | Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers |
CA2740029C (en) * | 2008-05-16 | 2016-12-20 | Axis, Inc. | Pharmaceutical composition for treatment of fibromyalgia |
US8771735B2 (en) * | 2008-11-04 | 2014-07-08 | Jazz Pharmaceuticals, Inc. | Immediate release dosage forms of sodium oxybate |
US8778398B2 (en) | 2008-11-04 | 2014-07-15 | Jazz Pharmaceuticals, Inc. | Immediate release formulations and dosage forms of gamma-hydroxybutyrate |
DK2421808T3 (da) | 2009-04-23 | 2013-11-04 | Concert Pharmaceuticals Inc | 4-Hydroxysmørsyreanaloger |
WO2011119839A1 (en) | 2010-03-24 | 2011-09-29 | Jazz Pharmaceuticals, Inc. | Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances |
CN103370289B (zh) | 2011-02-14 | 2015-09-09 | 康塞特医药品有限公司 | 4-羟基丁酸氘化类似物 |
CA2732479A1 (en) * | 2011-02-14 | 2012-08-14 | Concert Pharmaceuticals, Inc. | 4-hydroxybutyric acid analogs |
EP2961738B1 (de) | 2012-11-14 | 2019-12-25 | CJ CheilJedang Corporation | Herstellung von salzen von 4-hydroxybutyrate mittels biobasierter rohstoffe |
US8591922B1 (en) | 2012-12-14 | 2013-11-26 | Jazz Pharmacuticals, Inc. | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders |
US9050302B2 (en) | 2013-03-01 | 2015-06-09 | Jazz Pharmaceuticals Ireland Limited | Method of administration of gamma hydroxybutyrate with monocarboxylate transporters |
WO2016025329A1 (en) | 2014-08-15 | 2016-02-18 | Tepha, Inc. | Self-retaining sutures of poly-4-hydroxybutyrate and copolymers thereof |
EP3230500A1 (de) | 2014-12-11 | 2017-10-18 | Tepha, Inc. | Verfahren zur ausrichtung von multifilamentgarn und monofilamenten aus poly-4-hydroxybutyrat und copolymere davon |
US10626521B2 (en) | 2014-12-11 | 2020-04-21 | Tepha, Inc. | Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof |
DK3237044T3 (da) | 2014-12-22 | 2019-12-09 | Sanofi Aventis Deutschland | Automatisk injektionsanordning med elektromagnetisk drivenhed |
US10398662B1 (en) | 2015-02-18 | 2019-09-03 | Jazz Pharma Ireland Limited | GHB formulation and method for its manufacture |
FR3049463B1 (fr) | 2016-04-01 | 2019-07-05 | Debregeas Et Associes Pharma | Doses unitaires a liberation immediate de ghb ou de l'un de ses sels therapeutiquement acceptables administrees par voie orale et leur utilisation pour maintenir l'abstinence alcoolique |
US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US20180263936A1 (en) | 2017-03-17 | 2018-09-20 | Jazz Pharmaceuticals Ireland Limited | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders |
CN112004520A (zh) | 2017-12-18 | 2020-11-27 | 特瑞斯制药公司 | 包括具有触发脉冲药物释放的胃内滞留筏形成***的调节释放药物粉末组合物 |
US11337920B2 (en) | 2017-12-18 | 2022-05-24 | Tris Pharma, Inc. | Pharmaceutical composition comprising GHB gastro-retentive raft forming systems having trigger pulse drug release |
US11666546B2 (en) | 2017-12-18 | 2023-06-06 | Tris Pharma, Inc | GHB pharmaceutical compositions comprising a floating interpenetrating polymer network forming system |
KR20210094513A (ko) | 2018-11-19 | 2021-07-29 | 재즈 파마슈티칼즈 아일랜드 리미티드 | 알코올-내성 약물 제형 |
BR112021013766A2 (pt) | 2019-03-01 | 2021-09-21 | Flamel Ireland Limited | Composições de gama-hidroxibutirato com farmacocinética melhorada no estado alimentado |
AU2021362222A1 (en) | 2020-10-16 | 2023-06-01 | Jazz Pharmaceuticals Ireland Limited | Treatment methods using ghb |
US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60168044A (ja) * | 1984-02-10 | 1985-08-31 | Sharp Corp | 感湿素子 |
US4738985A (en) * | 1986-03-19 | 1988-04-19 | The University Of Toronto Innovations Foundations | Pharmaceutical composition and treatment |
JPH05262654A (ja) * | 1992-03-18 | 1993-10-12 | Kaken Pharmaceut Co Ltd | 慢性疲労症候群治療剤 |
ITTO930510A1 (it) * | 1993-07-09 | 1993-10-07 | Walter Tarello | Farmaci attivi contro la chronic fatigue syndrome (c.f.s.) |
IT1266565B1 (it) * | 1993-07-22 | 1997-01-09 | Ct Lab Farm Srl | Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico. |
US5840331A (en) * | 1995-06-07 | 1998-11-24 | Arch Development Corporation | Use of γ-hydroxybutyrate for the stimulation of sleep-related secretion growth hormone and prolactin |
-
1997
- 1997-08-29 US US08/920,979 patent/US5990162A/en not_active Expired - Lifetime
-
1998
- 1998-08-27 PT PT98941094T patent/PT1017381E/pt unknown
- 1998-08-27 NZ NZ502983A patent/NZ502983A/en not_active IP Right Cessation
- 1998-08-27 IL IL13466998A patent/IL134669A0/xx active IP Right Grant
- 1998-08-27 CA CA002301723A patent/CA2301723C/en not_active Expired - Fee Related
- 1998-08-27 WO PCT/US1998/017818 patent/WO1999009972A1/en active IP Right Grant
- 1998-08-27 ES ES98941094T patent/ES2235355T3/es not_active Expired - Lifetime
- 1998-08-27 DE DE69829112T patent/DE69829112T2/de not_active Expired - Fee Related
- 1998-08-27 CZ CZ2000741A patent/CZ295248B6/cs not_active IP Right Cessation
- 1998-08-27 AT AT98941094T patent/ATE289508T1/de active
- 1998-08-27 AU AU89237/98A patent/AU737086B2/en not_active Ceased
- 1998-08-27 EP EP98941094A patent/EP1017381B1/de not_active Expired - Lifetime
- 1998-08-27 JP JP2000507362A patent/JP3660587B2/ja not_active Expired - Fee Related
-
2000
- 2000-02-22 IL IL134669A patent/IL134669A/en not_active IP Right Cessation
- 2000-02-28 NO NO20000989A patent/NO326479B1/no not_active IP Right Cessation
- 2000-12-30 HK HK00108578A patent/HK1029278A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL134669A0 (en) | 2001-04-30 |
US5990162A (en) | 1999-11-23 |
JP2001513552A (ja) | 2001-09-04 |
NO20000989L (no) | 2000-04-03 |
WO1999009972A1 (en) | 1999-03-04 |
JP3660587B2 (ja) | 2005-06-15 |
PT1017381E (pt) | 2005-06-30 |
EP1017381B1 (de) | 2005-02-23 |
DE69829112T2 (de) | 2005-08-25 |
AU737086B2 (en) | 2001-08-09 |
ES2235355T3 (es) | 2005-07-01 |
AU8923798A (en) | 1999-03-16 |
CZ295248B6 (cs) | 2005-06-15 |
HK1029278A1 (en) | 2001-03-30 |
NO20000989D0 (no) | 2000-02-28 |
CA2301723C (en) | 2008-02-19 |
CZ2000741A3 (cs) | 2000-09-13 |
NO326479B1 (no) | 2008-12-15 |
IL134669A (en) | 2006-08-20 |
DE69829112D1 (de) | 2005-03-31 |
NZ502983A (en) | 2001-08-31 |
EP1017381A1 (de) | 2000-07-12 |
CA2301723A1 (en) | 1999-03-04 |
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