ATE28639T1 - Derivate von 4-(3-alkynyloxy-2-hydroxy-propyl)piperazin-1-yl-n-phenylacetamid, ihre herstellung und ihre therapeutische verwendung. - Google Patents
Derivate von 4-(3-alkynyloxy-2-hydroxy-propyl)piperazin-1-yl-n-phenylacetamid, ihre herstellung und ihre therapeutische verwendung.Info
- Publication number
- ATE28639T1 ATE28639T1 AT84401824T AT84401824T ATE28639T1 AT E28639 T1 ATE28639 T1 AT E28639T1 AT 84401824 T AT84401824 T AT 84401824T AT 84401824 T AT84401824 T AT 84401824T AT E28639 T1 ATE28639 T1 AT E28639T1
- Authority
- AT
- Austria
- Prior art keywords
- atoms
- branched
- phenylacetamide
- alkynyloxy
- piperazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8314720A FR2552083B1 (fr) | 1983-09-15 | 1983-09-15 | Derives de (alkynyloxy-3 hydroxy-2-propyl)-4 piperazinyl-1 n-phenyl acetamide, leur preparation et leur application en therapeutique |
EP84401824A EP0143016B1 (de) | 1983-09-15 | 1984-09-14 | Derivate von 4-(3-Alkynyloxy-2-hydroxy-propyl)-piperazin-1-yl-N-phenylacetamid, ihre Herstellung und ihre therapeutische Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE28639T1 true ATE28639T1 (de) | 1987-08-15 |
Family
ID=9292262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT84401824T ATE28639T1 (de) | 1983-09-15 | 1984-09-14 | Derivate von 4-(3-alkynyloxy-2-hydroxy-propyl)piperazin-1-yl-n-phenylacetamid, ihre herstellung und ihre therapeutische verwendung. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0143016B1 (de) |
JP (1) | JPS60142972A (de) |
KR (1) | KR850002477A (de) |
AT (1) | ATE28639T1 (de) |
AU (1) | AU572888B2 (de) |
DE (1) | DE3465085D1 (de) |
DK (1) | DK439384A (de) |
ES (2) | ES8602724A1 (de) |
FI (1) | FI77243C (de) |
FR (1) | FR2552083B1 (de) |
GR (1) | GR80359B (de) |
HU (1) | HU192994B (de) |
PT (1) | PT79214B (de) |
ZA (1) | ZA846937B (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6552023B2 (en) | 2000-02-22 | 2003-04-22 | Cv Therapeutics, Inc. | Aralkyl substituted piperazine compounds |
US6677336B2 (en) | 2000-02-22 | 2004-01-13 | Cv Therapeutics, Inc. | Substituted piperazine compounds |
WO2001062744A2 (en) * | 2000-02-22 | 2001-08-30 | Cv Therapeutics, Inc. | Substituted piperazine compounds |
US6451798B2 (en) | 2000-02-22 | 2002-09-17 | Cv Therapeutics, Inc. | Substituted alkyl piperazine derivatives |
US6693099B2 (en) * | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
EP2142506B1 (de) * | 2007-03-30 | 2013-10-16 | Council of Scientific & Industrial Research | Neue benzophenonhybride als potentielle antikrebsmittel und verfahren zu deren herstellung |
JP6077344B2 (ja) * | 2013-03-12 | 2017-02-08 | 花王株式会社 | ピペラジン誘導体を含む漂白剤組成物 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2173869B1 (de) * | 1972-04-13 | 1975-12-26 | Cerm Cent Europ Rech Mauvernay | |
US3951979A (en) * | 1972-04-13 | 1976-04-20 | Roland Yves Mauvernary | New amino propanediol derivatives |
FR2403330A1 (fr) * | 1977-06-16 | 1979-04-13 | Fabre Sa Pierre | Nouveaux derives de benzoyl-2-chloro-4-glycinanilides substitues, leur procede de preparation et leur application en tant que medicaments |
-
1983
- 1983-09-15 FR FR8314720A patent/FR2552083B1/fr not_active Expired
-
1984
- 1984-09-04 ZA ZA846937A patent/ZA846937B/xx unknown
- 1984-09-10 AU AU32861/84A patent/AU572888B2/en not_active Ceased
- 1984-09-13 JP JP59192411A patent/JPS60142972A/ja active Pending
- 1984-09-13 GR GR80359A patent/GR80359B/el unknown
- 1984-09-13 ES ES535899A patent/ES8602724A1/es not_active Expired
- 1984-09-14 HU HU843473A patent/HU192994B/hu not_active IP Right Cessation
- 1984-09-14 DE DE8484401824T patent/DE3465085D1/de not_active Expired
- 1984-09-14 EP EP84401824A patent/EP0143016B1/de not_active Expired
- 1984-09-14 FI FI843617A patent/FI77243C/fi not_active IP Right Cessation
- 1984-09-14 DK DK439384A patent/DK439384A/da not_active Application Discontinuation
- 1984-09-14 PT PT79214A patent/PT79214B/pt unknown
- 1984-09-14 AT AT84401824T patent/ATE28639T1/de not_active IP Right Cessation
- 1984-09-14 KR KR1019840005613A patent/KR850002477A/ko not_active Application Discontinuation
-
1985
- 1985-07-05 ES ES544919A patent/ES8607265A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0143016B1 (de) | 1987-07-29 |
ZA846937B (en) | 1985-04-24 |
DK439384D0 (da) | 1984-09-14 |
EP0143016A1 (de) | 1985-05-29 |
FI77243C (fi) | 1989-02-10 |
DE3465085D1 (en) | 1987-09-03 |
PT79214A (en) | 1984-10-01 |
FI843617A0 (fi) | 1984-09-14 |
PT79214B (en) | 1986-08-22 |
ES544919A0 (es) | 1986-05-16 |
AU3286184A (en) | 1985-03-21 |
JPS60142972A (ja) | 1985-07-29 |
FI843617L (fi) | 1985-03-16 |
ES8607265A1 (es) | 1986-05-16 |
HU192994B (en) | 1987-08-28 |
GR80359B (en) | 1985-01-11 |
ES535899A0 (es) | 1985-12-01 |
FR2552083A1 (fr) | 1985-03-22 |
HUT35253A (en) | 1985-06-28 |
KR850002477A (ko) | 1985-05-13 |
FR2552083B1 (fr) | 1986-05-09 |
FI77243B (fi) | 1988-10-31 |
DK439384A (da) | 1985-03-16 |
AU572888B2 (en) | 1988-05-19 |
ES8602724A1 (es) | 1985-12-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |