ATE253061T1 - Zur behandlung von krebs nützliche thiophen- und furan-2,5-dicarboxamide - Google Patents
Zur behandlung von krebs nützliche thiophen- und furan-2,5-dicarboxamideInfo
- Publication number
- ATE253061T1 ATE253061T1 AT99926680T AT99926680T ATE253061T1 AT E253061 T1 ATE253061 T1 AT E253061T1 AT 99926680 T AT99926680 T AT 99926680T AT 99926680 T AT99926680 T AT 99926680T AT E253061 T1 ATE253061 T1 AT E253061T1
- Authority
- AT
- Austria
- Prior art keywords
- cancer
- dicarboxamide
- furan
- thiophene
- useful
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 2
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 2
- YVORDIMCXSWNQQ-UHFFFAOYSA-N furan-2,5-dicarboxamide Chemical compound NC(=O)C1=CC=C(C(N)=O)O1 YVORDIMCXSWNQQ-UHFFFAOYSA-N 0.000 title 1
- 229930192474 thiophene Natural products 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 102000006495 integrins Human genes 0.000 abstract 2
- 108010044426 integrins Proteins 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9106398P | 1998-06-29 | 1998-06-29 | |
| PCT/IB1999/001221 WO2000000486A1 (en) | 1998-06-29 | 1999-06-29 | Thiophene and furan 2,5-dicarboxamides useful in the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE253061T1 true ATE253061T1 (de) | 2003-11-15 |
Family
ID=22225790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99926680T ATE253061T1 (de) | 1998-06-29 | 1999-06-29 | Zur behandlung von krebs nützliche thiophen- und furan-2,5-dicarboxamide |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6960594B2 (de) |
| EP (1) | EP1091952B1 (de) |
| AT (1) | ATE253061T1 (de) |
| AU (1) | AU4385399A (de) |
| DE (1) | DE69912432D1 (de) |
| WO (1) | WO2000000486A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9805655D0 (en) | 1998-03-16 | 1998-05-13 | Celltech Therapeutics Ltd | Chemical compounds |
| US6521626B1 (en) | 1998-03-24 | 2003-02-18 | Celltech R&D Limited | Thiocarboxamide derivatives |
| GB9814414D0 (en) | 1998-07-03 | 1998-09-02 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9826174D0 (en) | 1998-11-30 | 1999-01-20 | Celltech Therapeutics Ltd | Chemical compounds |
| AU5379900A (en) | 1999-06-07 | 2000-12-28 | Shire Biochem Inc. | Thiophene integrin inhibitors |
| EP1332132B1 (de) | 2000-04-17 | 2007-10-10 | UCB Pharma, S.A. | Enamin-derivate als zell-adhäsionsmoleküle |
| FR2808798A1 (fr) * | 2000-05-09 | 2001-11-16 | Hoechst Marion Roussel Inc | Nouveaux derives antagonistes du recepteur de la vitronectine |
| SK288015B6 (sk) * | 2001-06-11 | 2012-11-05 | Virochem Pharma Inc. | Thiophene derivatives as antiviral agents for flavivirus infection |
| US6924276B2 (en) | 2001-09-10 | 2005-08-02 | Warner-Lambert Company | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors |
| CN100413861C (zh) | 2002-12-10 | 2008-08-27 | 维勒凯姆制药股份有限公司 | 用于治疗或预防黄病毒感染的化合物 |
| UA87854C2 (en) | 2004-06-07 | 2009-08-25 | Мерк Энд Ко., Инк. | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators |
| AP2007004245A0 (en) | 2005-05-13 | 2007-12-31 | Virochem Pharma Inc | Compounds and methods for the treatment or prevention of flavivirus infections |
| NZ576780A (en) | 2006-11-15 | 2011-12-22 | Virochem Pharma Inc | Thiophene analogues for the treatment or prevention of flavivirus infections |
| WO2011025706A2 (en) * | 2009-08-26 | 2011-03-03 | Schering Corporation | Heterocyclic amide compounds as protein kinase inhibitors |
| US8337334B2 (en) * | 2009-09-14 | 2012-12-25 | Nike, Inc. | Golf balls with clusters of dimples having non-uniform dimple profiles |
| CN105209037A (zh) | 2013-03-29 | 2015-12-30 | 雅沃科学有限责任公司 | 用于治疗癌症、神经障碍和纤维化病症的脂类呋喃、吡咯和噻吩化合物 |
| KR20160147007A (ko) | 2014-05-30 | 2016-12-21 | 화이자 인코포레이티드 | 선택적인 안드로겐 수용체 조절제로서의 카보니트릴 유도체 |
| US20170312246A1 (en) | 2016-04-27 | 2017-11-02 | Avoscience, Llc | Lipidic furan, pyrrole, and thiophene compounds for use in the treatment of atrophic vaginitis |
| WO2023275715A1 (en) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Metabolites of selective androgen receptor modulators |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU674553B2 (en) * | 1992-10-14 | 1997-01-02 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| ES2185009T3 (es) * | 1996-04-10 | 2003-04-16 | Merck & Co Inc | Antagonistas de alfa y beta 3'. |
-
1999
- 1999-06-29 WO PCT/IB1999/001221 patent/WO2000000486A1/en active IP Right Grant
- 1999-06-29 EP EP99926680A patent/EP1091952B1/de not_active Expired - Lifetime
- 1999-06-29 DE DE69912432T patent/DE69912432D1/de not_active Expired - Lifetime
- 1999-06-29 AU AU43853/99A patent/AU4385399A/en not_active Abandoned
- 1999-06-29 AT AT99926680T patent/ATE253061T1/de not_active IP Right Cessation
-
2002
- 2002-01-16 US US10/046,396 patent/US6960594B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000000486A1 (en) | 2000-01-06 |
| AU4385399A (en) | 2000-01-17 |
| DE69912432D1 (de) | 2003-12-04 |
| EP1091952A1 (de) | 2001-04-18 |
| US6960594B2 (en) | 2005-11-01 |
| EP1091952B1 (de) | 2003-10-29 |
| US20020137947A1 (en) | 2002-09-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |