ATE251886T1 - Verwendunf von apoe zum binden von tau und map2c proteinen und zur behandlung von alzheimer's krankheit - Google Patents
Verwendunf von apoe zum binden von tau und map2c proteinen und zur behandlung von alzheimer's krankheitInfo
- Publication number
- ATE251886T1 ATE251886T1 AT94925756T AT94925756T ATE251886T1 AT E251886 T1 ATE251886 T1 AT E251886T1 AT 94925756 T AT94925756 T AT 94925756T AT 94925756 T AT94925756 T AT 94925756T AT E251886 T1 ATE251886 T1 AT E251886T1
- Authority
- AT
- Austria
- Prior art keywords
- apoe
- map2c
- disease
- subject
- binding
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Marine Sciences & Fisheries (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11491093A | 1993-08-31 | 1993-08-31 | |
PCT/US1994/008881 WO1995006456A1 (en) | 1993-08-31 | 1994-08-05 | METHODS AND COMPOSITIONS FOR BINDING TAU AND MAP2c PROTEINS |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE251886T1 true ATE251886T1 (de) | 2003-11-15 |
Family
ID=22358180
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94925756T ATE251886T1 (de) | 1993-08-31 | 1994-08-05 | Verwendunf von apoe zum binden von tau und map2c proteinen und zur behandlung von alzheimer's krankheit |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0716591B1 (de) |
AT (1) | ATE251886T1 (de) |
AU (1) | AU681434B2 (de) |
CA (1) | CA2170727A1 (de) |
DE (1) | DE69433243T2 (de) |
WO (1) | WO1995006456A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9414624D0 (en) * | 1994-07-20 | 1994-09-07 | Smithkline Beecham Plc | Novel method |
US5767337A (en) * | 1995-07-31 | 1998-06-16 | Duke University | Creation of human apolipoprotein E isoform specific transgenic mice in apolipoprotein deficient "knockout" mice |
US7964598B2 (en) | 1995-10-17 | 2011-06-21 | The J. David Gladstone Institutes | ApoE4 domain interaction inhibitors and methods of use thereof |
WO1997016194A1 (en) * | 1995-11-02 | 1997-05-09 | Warner-Lambert Company | Naphthylazo inhibition of amyloidosis |
US6313089B1 (en) | 1997-08-20 | 2001-11-06 | Duke University | Complexes of apolipoprotein E and ciliary neurotrophic factor (CNTF) and methods of use |
US7205280B2 (en) | 1998-03-11 | 2007-04-17 | Cognosci, Inc. | Methods of suppressing microglial activation |
US20030077641A1 (en) | 1998-03-11 | 2003-04-24 | Laskowitz Daniel T. | Methods of suppressing microglial activation and systemic inflammatory responses |
US6046381A (en) * | 1998-04-30 | 2000-04-04 | The Regents Of The University Of California | Apolipoprotein E transgenic mice and assay methods |
JP2002530122A (ja) * | 1998-11-25 | 2002-09-17 | サイオス インコーポレイテッド | アミロイド関連疾患の予防及び治療 |
US6017913A (en) * | 1999-05-03 | 2000-01-25 | Warner-Lambert Company | Naphthylazo inhibition of amyloidosis |
WO2001056579A1 (en) * | 2000-02-04 | 2001-08-09 | Esperion Therapeutics Inc. | Methods for treating alzheimer's disease |
US8034762B2 (en) | 2004-09-02 | 2011-10-11 | Cognosci, Inc. | Treatment of subarachnoid hemorrhage with Apo E analogs |
WO2006029028A2 (en) | 2004-09-02 | 2006-03-16 | Cognosci, Inc. | Improved apo e analogs and methods for their use |
CN109942714B (zh) * | 2019-04-02 | 2022-07-08 | 中国药科大学 | 一种功能多肽及应用 |
-
1994
- 1994-08-05 CA CA002170727A patent/CA2170727A1/en not_active Abandoned
- 1994-08-05 WO PCT/US1994/008881 patent/WO1995006456A1/en active IP Right Grant
- 1994-08-05 DE DE69433243T patent/DE69433243T2/de not_active Expired - Fee Related
- 1994-08-05 EP EP94925756A patent/EP0716591B1/de not_active Expired - Lifetime
- 1994-08-05 AT AT94925756T patent/ATE251886T1/de not_active IP Right Cessation
- 1994-08-05 AU AU75561/94A patent/AU681434B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP0716591A1 (de) | 1996-06-19 |
DE69433243D1 (de) | 2003-11-20 |
CA2170727A1 (en) | 1995-03-09 |
AU7556194A (en) | 1995-03-22 |
AU681434B2 (en) | 1997-08-28 |
EP0716591B1 (de) | 2003-10-15 |
WO1995006456A1 (en) | 1995-03-09 |
DE69433243T2 (de) | 2004-07-29 |
EP0716591A4 (de) | 1998-02-04 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |