ATE246692T1 - Verfahren zur reinigung von phosphatidylserin - Google Patents
Verfahren zur reinigung von phosphatidylserinInfo
- Publication number
- ATE246692T1 ATE246692T1 AT01124577T AT01124577T ATE246692T1 AT E246692 T1 ATE246692 T1 AT E246692T1 AT 01124577 T AT01124577 T AT 01124577T AT 01124577 T AT01124577 T AT 01124577T AT E246692 T1 ATE246692 T1 AT E246692T1
- Authority
- AT
- Austria
- Prior art keywords
- phosphatidylserine
- purifying
- purifying phosphatidylserine
- phosphatidylation
- phospholipase
- Prior art date
Links
- TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 title abstract 2
- ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 title abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- 150000002433 hydrophilic molecules Chemical class 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
- C07F9/103—Extraction or purification by physical or chemical treatment of natural phosphatides; Preparation of compositions containing phosphatides of unknown structure
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2000MI002631A IT1319679B1 (it) | 2000-12-05 | 2000-12-05 | Processo di purificazione di fosfatidilserina. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE246692T1 true ATE246692T1 (de) | 2003-08-15 |
Family
ID=11446181
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01124577T ATE246692T1 (de) | 2000-12-05 | 2001-10-15 | Verfahren zur reinigung von phosphatidylserin |
Country Status (10)
Country | Link |
---|---|
US (2) | US6645742B2 (de) |
EP (1) | EP1213294B2 (de) |
JP (1) | JP4156228B2 (de) |
AT (1) | ATE246692T1 (de) |
DE (1) | DE60100565T3 (de) |
DK (1) | DK1213294T3 (de) |
ES (1) | ES2203572T5 (de) |
IT (1) | IT1319679B1 (de) |
PT (1) | PT1213294E (de) |
SI (1) | SI1213294T1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1319679B1 (it) | 2000-12-05 | 2003-10-23 | Chemi Spa | Processo di purificazione di fosfatidilserina. |
US6878532B1 (en) | 2003-04-28 | 2005-04-12 | Sioux Biochemical, Inc. | Method of producing phosphatidylserine |
IL158139A0 (en) | 2003-09-25 | 2004-09-27 | Enzymotec Ltd | Stabilized formulations of phosphatidyl serine |
US7935365B2 (en) * | 2003-10-22 | 2011-05-03 | Enzymotec, Ltd. | Glycerophospholipids for the improvement of cognitive functions |
US20050130937A1 (en) | 2003-10-22 | 2005-06-16 | Enzymotec Ltd. | Lipids containing omega-3 and omega-6 fatty acids |
US8052992B2 (en) | 2003-10-22 | 2011-11-08 | Enzymotec Ltd. | Glycerophospholipids containing omega-3 and omega-6 fatty acids and their use in the treatment and improvement of cognitive functions |
WO2005090587A1 (ja) * | 2004-03-18 | 2005-09-29 | Nagase Chemtex Corporation | 酵素の除去方法および該方法を用いるリン脂質の塩基転移または加水分解方法 |
US7465717B2 (en) * | 2004-09-27 | 2008-12-16 | Soymor | Process for releasing and extracting phosphatides from a phosphatide-containing matrix |
ITPD20050164A1 (it) | 2005-05-30 | 2006-11-30 | Fidia Farmaceutici | Processo per la preparazione e l'isolamento di fosfatidi |
JP4887674B2 (ja) * | 2005-07-07 | 2012-02-29 | ナガセケムテックス株式会社 | リン脂質組成物の製造方法 |
JP4931527B2 (ja) * | 2006-09-20 | 2012-05-16 | 富士フイルム株式会社 | フッ素化ホスファチジルセリン化合物 |
JP5894377B2 (ja) * | 2011-06-03 | 2016-03-30 | 株式会社カネカ | リン脂質の製造方法 |
CN103074390A (zh) * | 2011-11-02 | 2013-05-01 | 江南大学 | 一种酶法制备不含溶血磷脂和磷脂酸的磷脂酰丙醇的方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1504125A (en) | 1974-03-22 | 1978-03-15 | Unilever Ltd | Process for purifying phosphatides |
US5084215A (en) * | 1984-02-13 | 1992-01-28 | The Liposome Company, Inc. | Process for purification of phospholipids |
JPS6336790A (ja) | 1986-08-01 | 1988-02-17 | Nippon Oil & Fats Co Ltd | リン脂質の塩基交換反応法 |
JP2987682B2 (ja) | 1995-06-19 | 1999-12-06 | 花王株式会社 | 酸性リン脂質の濃縮法 |
US5700668A (en) * | 1995-12-08 | 1997-12-23 | Italfarmaco Sud S.P.A. | Process for the industrial preparation of phosphatidylserine |
DE19917249C2 (de) * | 1999-02-26 | 2001-09-27 | Meyer Lucas Gmbh & Co | Verfahren zur Herstellung von Phosphatidylserin-Produkten |
IT1311929B1 (it) * | 1999-04-28 | 2002-03-20 | Chemi Spa | Procedimento per la preparazione di fosfatidilserine. |
IT1319679B1 (it) | 2000-12-05 | 2003-10-23 | Chemi Spa | Processo di purificazione di fosfatidilserina. |
-
2000
- 2000-12-05 IT IT2000MI002631A patent/IT1319679B1/it active
-
2001
- 2001-10-15 DK DK01124577T patent/DK1213294T3/da active
- 2001-10-15 AT AT01124577T patent/ATE246692T1/de not_active IP Right Cessation
- 2001-10-15 PT PT01124577T patent/PT1213294E/pt unknown
- 2001-10-15 ES ES01124577T patent/ES2203572T5/es not_active Expired - Lifetime
- 2001-10-15 EP EP01124577A patent/EP1213294B2/de not_active Expired - Lifetime
- 2001-10-15 DE DE60100565T patent/DE60100565T3/de not_active Expired - Lifetime
- 2001-10-15 SI SI200130023T patent/SI1213294T1/xx unknown
- 2001-10-18 US US09/982,468 patent/US6645742B2/en not_active Ceased
- 2001-11-08 JP JP2001342776A patent/JP4156228B2/ja not_active Expired - Lifetime
-
2011
- 2011-06-24 US US13/167,785 patent/USRE43764E1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES2203572T5 (es) | 2009-03-01 |
US20020103393A1 (en) | 2002-08-01 |
DK1213294T3 (da) | 2003-11-17 |
EP1213294A1 (de) | 2002-06-12 |
IT1319679B1 (it) | 2003-10-23 |
JP2002193982A (ja) | 2002-07-10 |
ES2203572T3 (es) | 2004-04-16 |
PT1213294E (pt) | 2003-12-31 |
EP1213294B2 (de) | 2008-10-22 |
USRE43764E1 (en) | 2012-10-23 |
ITMI20002631A1 (it) | 2002-06-05 |
EP1213294B1 (de) | 2003-08-06 |
DE60100565T3 (de) | 2009-04-23 |
US6645742B2 (en) | 2003-11-11 |
DE60100565D1 (de) | 2003-09-11 |
DE60100565T2 (de) | 2004-03-25 |
JP4156228B2 (ja) | 2008-09-24 |
SI1213294T1 (en) | 2003-12-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1213294 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |