ATE245454T1 - Polyen-makrolidderivate, verwendung zur vektorisierung von molekülen - Google Patents

Polyen-makrolidderivate, verwendung zur vektorisierung von molekülen

Info

Publication number
ATE245454T1
ATE245454T1 AT99913358T AT99913358T ATE245454T1 AT E245454 T1 ATE245454 T1 AT E245454T1 AT 99913358 T AT99913358 T AT 99913358T AT 99913358 T AT99913358 T AT 99913358T AT E245454 T1 ATE245454 T1 AT E245454T1
Authority
AT
Austria
Prior art keywords
molecules
vectorization
polyene macrolide
macrolide derivatives
negatively charged
Prior art date
Application number
AT99913358T
Other languages
English (en)
Inventor
Jacques Bolard
Christine Garcia
Olivier Seksek
Edward Borowski
Jolanta Grzybowska
Original Assignee
Univ Paris Curie
Technical University Of Gdansk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Paris Curie, Technical University Of Gdansk filed Critical Univ Paris Curie
Application granted granted Critical
Publication of ATE245454T1 publication Critical patent/ATE245454T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Carbon And Carbon Compounds (AREA)
AT99913358T 1998-04-07 1999-04-07 Polyen-makrolidderivate, verwendung zur vektorisierung von molekülen ATE245454T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9804317A FR2776927B1 (fr) 1998-04-07 1998-04-07 Compositions pour la vectorisation de molecules
PCT/FR1999/000808 WO1999051274A1 (fr) 1998-04-07 1999-04-07 Derives de macrolide polyenique, utilisation pour la vectorisation de molecules

Publications (1)

Publication Number Publication Date
ATE245454T1 true ATE245454T1 (de) 2003-08-15

Family

ID=9524954

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99913358T ATE245454T1 (de) 1998-04-07 1999-04-07 Polyen-makrolidderivate, verwendung zur vektorisierung von molekülen

Country Status (9)

Country Link
US (1) US20040002465A1 (de)
EP (1) EP1067969B1 (de)
AT (1) ATE245454T1 (de)
CA (1) CA2327737A1 (de)
DE (1) DE69909766T2 (de)
ES (1) ES2204114T3 (de)
FR (1) FR2776927B1 (de)
PL (1) PL199213B1 (de)
WO (1) WO1999051274A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20010018A2 (en) * 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
US9447136B2 (en) 2012-03-09 2016-09-20 Blirt S.A. Semisynthetic derivatives of Nystatin A1
KR20150027217A (ko) * 2012-06-15 2015-03-11 블러트 에스.에이. 항진균성 항생 암포테리신 b의 n-치환된 제2 세대 유도체, 및 이의 제조 및 응용 방법
WO2015190587A1 (ja) 2014-06-12 2015-12-17 塩野義製薬株式会社 ポリエンマクロライド誘導体
US20230016424A1 (en) * 2019-08-08 2023-01-19 The Board Of Trustees Of The University Of Illinois Hybrid amide derivatives of amphotericin b
CN115536716A (zh) * 2021-06-29 2022-12-30 中国科学院上海药物研究所 两性霉素b半合成衍生物及其制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272525A (en) * 1978-10-23 1981-06-09 Schering Corporation Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them
US4950652A (en) * 1987-03-23 1990-08-21 Hem Research, Inc. dsRNAs for combination therapy in the treatment of viral diseases
GB9203476D0 (en) * 1992-02-19 1992-04-08 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
DE69909766T2 (de) 2004-06-03
ES2204114T3 (es) 2004-04-16
PL199213B1 (pl) 2008-08-29
DE69909766D1 (de) 2003-08-28
EP1067969A1 (de) 2001-01-17
WO1999051274A1 (fr) 1999-10-14
US20040002465A1 (en) 2004-01-01
FR2776927B1 (fr) 2002-07-05
FR2776927A1 (fr) 1999-10-08
EP1067969B1 (de) 2003-07-23
PL343365A1 (en) 2001-08-13
CA2327737A1 (fr) 1999-10-14

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties