ATE245153T1 - Heteroaryl-diazacycloalkane, ihre herstellung und verwendung - Google Patents
Heteroaryl-diazacycloalkane, ihre herstellung und verwendungInfo
- Publication number
- ATE245153T1 ATE245153T1 AT00920421T AT00920421T ATE245153T1 AT E245153 T1 ATE245153 T1 AT E245153T1 AT 00920421 T AT00920421 T AT 00920421T AT 00920421 T AT00920421 T AT 00920421T AT E245153 T1 ATE245153 T1 AT E245153T1
- Authority
- AT
- Austria
- Prior art keywords
- diseases
- disorders
- disorders related
- cholinergic
- diazacycloalkanes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA199900571 | 1999-04-26 | ||
DKPA199901504 | 1999-10-20 | ||
PCT/DK2000/000202 WO2000064885A1 (en) | 1999-04-26 | 2000-04-19 | Heteroaryl diazacycloalkanes, their preparation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE245153T1 true ATE245153T1 (de) | 2003-08-15 |
Family
ID=26064237
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00920421T ATE245153T1 (de) | 1999-04-26 | 2000-04-19 | Heteroaryl-diazacycloalkane, ihre herstellung und verwendung |
Country Status (10)
Country | Link |
---|---|
US (2) | US7064118B2 (de) |
EP (1) | EP1175416B1 (de) |
JP (1) | JP2002543070A (de) |
CN (1) | CN1348449A (de) |
AT (1) | ATE245153T1 (de) |
AU (1) | AU773830B2 (de) |
CA (1) | CA2367695A1 (de) |
DE (1) | DE60003911T2 (de) |
NZ (1) | NZ514021A (de) |
WO (1) | WO2000064885A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1757600A2 (de) * | 2000-10-13 | 2007-02-28 | NeuroSearch A/S | Behandlung affektiver Störungen durch kombinierte Wirkung eines nikotinischen Rezeptoragonisten und einer monoaminergischen Substanz |
DK1406900T3 (da) | 2001-07-06 | 2007-01-29 | Neurosearch As | Hidtil ukendte forbindelser, fremstilling og anvendelse deraf |
US20040242641A1 (en) * | 2003-05-27 | 2004-12-02 | Buckley Michael J. | (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane is an effective analgesic agent |
WO2005014655A2 (en) * | 2003-08-08 | 2005-02-17 | Fresenius Kabi Deutschland Gmbh | Conjugates of hydroxyalkyl starch and a protein |
US20070191815A1 (en) | 2004-09-13 | 2007-08-16 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery |
CA2603701A1 (en) * | 2005-04-06 | 2006-10-19 | Banyu Pharmaceutical Co., Ltd. | 1,4-substituted piperazine derivative |
CN103977003A (zh) | 2007-04-02 | 2014-08-13 | 帕金森氏病研究院 | 用于降低治疗的副作用的方法和组合物 |
ES2325049B2 (es) * | 2008-02-21 | 2010-03-16 | Universidade De Santiago De Compostela | Deteccion y cuantificacion de iminas ciclicas basada en la union competitiva a receptores nicotinicos de acetilcolina. |
WO2010045212A2 (en) * | 2008-10-14 | 2010-04-22 | Psychogenics, Incstatuts | Nicotinic acetylcholine receptor ligands and the uses thereof |
ES2357934B2 (es) * | 2009-10-19 | 2011-09-08 | Universidad De Santiago De Compostela | Uso de un espirolido analogos y derivados para el tratamiento y/o la prevencion de patologias relacionadas con las proteinas tau y b-amiloide. |
JP5972367B2 (ja) * | 2011-07-01 | 2016-08-17 | リマインド・ナムローゼ・フエンノートシャップRemynd Nv | 神経変性疾患の治療に有用な1,2,4−チアジアゾール−5−イルピペラジン誘導体 |
AU2016211330A1 (en) | 2015-01-28 | 2017-08-03 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
JP2020503950A (ja) | 2017-01-06 | 2020-02-06 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | 経皮薬剤送達の装置及び方法 |
JP7420797B2 (ja) | 2018-05-29 | 2024-01-23 | モーニングサイド ベンチャー インベストメンツ リミテッド | 薬剤送達の方法及びシステム |
CN111808907B (zh) * | 2019-10-09 | 2021-07-09 | 北京原基华毅生物科技有限公司 | 调整觉醒的物质及方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4025617A (en) * | 1974-10-03 | 1977-05-24 | Millmaster Onyx Corporation | Anti-microbial quaternary ammonium co-polymers |
DK143899C (da) * | 1975-04-21 | 1982-04-13 | Merck & Co Inc | Analogifremgangsmaade til fremstilling af piperazinylpyrazinderivater |
US4163849A (en) * | 1978-03-17 | 1979-08-07 | Merck & Co., Inc. | Piperazinylpyrazines |
US4179563A (en) * | 1978-05-19 | 1979-12-18 | Warner-Lambert Company | 3-Aryloxy-substituted-aminopyridines and methods for their production |
US5001125A (en) * | 1984-03-26 | 1991-03-19 | Janssen Pharmaceutica N.V. | Anti-virally active pyridazinamines |
US4639415A (en) * | 1984-09-17 | 1987-01-27 | Konishiroku Photo Industry Co., Ltd. | Silver halide color photographic material containing a magenta color image-forming coupler |
ES8802151A1 (es) * | 1985-07-31 | 1988-04-01 | Janssen Pharmaceutica Nv | Un procedimiento para la preparacion de nuevos piridazinaminas. |
GB8603120D0 (en) * | 1986-02-07 | 1986-03-12 | Pfizer Ltd | Anti-dysrhythmia agents |
EP0361489A3 (de) * | 1988-09-30 | 1991-06-12 | Chugai Seiyaku Kabushiki Kaisha | 3,4-Diaminochinolin- und Pyridinverbindungen |
US4994456A (en) * | 1989-03-01 | 1991-02-19 | Nisshin Flour Milling Co., Ltd. | Pyridinecarboxylic acid amide derivatives and pharmaceutical compositions comprising same |
US5080754A (en) | 1990-07-20 | 1992-01-14 | The Research Foundation Of State University Of Ny | Method for reducing brightness reversion in lignin-containing pulps and article of manufacture thereof |
US5607936A (en) * | 1994-09-30 | 1997-03-04 | Merck & Co., Inc. | Substituted aryl piperazines as neurokinin antagonists |
US5929281A (en) | 1996-04-19 | 1999-07-27 | Tosoh Corporation | Process for producing heterocyclic aromatic amine or arylamine |
EP1491532B1 (de) * | 1997-10-27 | 2010-12-15 | NeuroSearch A/S | Heteroaryl Diazacycloalkane als cholinergische Ligande für Nikotin-Acetylcholin-Rezeptoren |
JP4388228B2 (ja) * | 1998-02-19 | 2009-12-24 | 興和株式会社 | 環状アミド化合物 |
EP1757600A2 (de) * | 2000-10-13 | 2007-02-28 | NeuroSearch A/S | Behandlung affektiver Störungen durch kombinierte Wirkung eines nikotinischen Rezeptoragonisten und einer monoaminergischen Substanz |
-
2000
- 2000-04-19 WO PCT/DK2000/000202 patent/WO2000064885A1/en active IP Right Grant
- 2000-04-19 EP EP00920421A patent/EP1175416B1/de not_active Expired - Lifetime
- 2000-04-19 CA CA002367695A patent/CA2367695A1/en not_active Abandoned
- 2000-04-19 JP JP2000614237A patent/JP2002543070A/ja not_active Withdrawn
- 2000-04-19 DE DE60003911T patent/DE60003911T2/de not_active Expired - Fee Related
- 2000-04-19 CN CN00806739A patent/CN1348449A/zh active Pending
- 2000-04-19 AU AU41006/00A patent/AU773830B2/en not_active Ceased
- 2000-04-19 NZ NZ514021A patent/NZ514021A/en unknown
- 2000-04-19 AT AT00920421T patent/ATE245153T1/de not_active IP Right Cessation
-
2001
- 2001-08-23 US US09/934,531 patent/US7064118B2/en not_active Expired - Fee Related
-
2005
- 2005-12-21 US US11/312,574 patent/US7282494B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US7282494B2 (en) | 2007-10-16 |
AU773830B2 (en) | 2004-06-10 |
WO2000064885A1 (en) | 2000-11-02 |
AU4100600A (en) | 2000-11-10 |
US20060100192A1 (en) | 2006-05-11 |
DE60003911T2 (de) | 2004-05-27 |
EP1175416B1 (de) | 2003-07-16 |
NZ514021A (en) | 2001-09-28 |
CA2367695A1 (en) | 2000-11-02 |
US7064118B2 (en) | 2006-06-20 |
JP2002543070A (ja) | 2002-12-17 |
DE60003911D1 (de) | 2003-08-21 |
EP1175416A1 (de) | 2002-01-30 |
CN1348449A (zh) | 2002-05-08 |
US20020045618A1 (en) | 2002-04-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |